Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00018 0.64 9.9 0.1 16 50 41 75 32 79 0.85

2 6 0.00023 0.8 9.6 0.2 23 46 76 99 72 105 0.88

3 6 0.0024 8.6 6.2 0.3 20 44 101 125 97 133 0.85

4 6 0.031 1.1e+02 2.7 0.1 21 44 130 153 127 161 0.86

5 6 0.0009 3.2 7.6 0.0 23 45 160 182 154 188 0.91

6 6 2.2 7.6e+03 -3.2 0.0 22 33 213 226 211 230 0.65

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00018	0.64	9.9	0.1	16	50	41	75	32	79	0.85
2	6	0.00023	0.8	9.6	0.2	23	46	76	99	72	105	0.88
3	6	0.0024	8.6	6.2	0.3	20	44	101	125	97	133	0.85
4	6	0.031	1.1e+02	2.7	0.1	21	44	130	153	127	161	0.86
5	6	0.0009	3.2	7.6	0.0	23	45	160	182	154	188	0.91
6	6	2.2	7.6e+03	-3.2	0.0	22	33	213	226	211	230	0.65

Coding Sequence: ATGGCCTCTAGGGAGGAATTTGAGGAAACAATGCCAATAAATGGTGTGGTAGCCATGTATACTTGCAAAAGGTGTAACAAGATATTCCCCTGTAAACGTGACCAACTTTTGCACAAAAAAGAAGTGCATTCCCAAACAAAATCCTCTTACGAATGTAAAATCTGTTCCAAATATTTCTGCAACAGCGGCAATTTAGAACGTCACATGAAGGTTCACAATGATGTGCGACCCTTTGTTTGTCGCATTTGTGGCAAGGCTTTCGCTCAGTCTGTCAACCTAAATCGTCATTATTCTGTACACAATGGCGAACGCCCGTATCCGTGTACGTTTTGTAATAAGACCTTTACCCAACAGTCGAACATGCAACGCCATCAACTAACACATACGGGAGAGAAACCATTTCGTTGTAAACGTTGTGGTCGTTATTTCTCCCAGCGTGTTAACCTTAAAAAGCATATTATGGGTCATTTGAATACCAAACCGTACACGTGCAAAATATGCCAAAAGTCATTTATACAATTGGGcaattttaagaaacatttacaGTCACATCTTAAGGATGGCATAGAGATCGATATGAAAGCGTTGGTGGCCGAGGCGCAGGCAATGGCCAAGCAAAGTTTGGAAATGGCCGATGAGCAACCAGtTGGCTTCGAATGTGCTGTCTGCCGatctattttcaataatttcactGATTTCGAAATGCATGAAAGTGAGTGCAACGACAATGCACAGGCAGCCATGGAACAGAAATACAATCCCGATGAACAACTACATGAAGTCGTTGTCGAAGAGGTTGAGGATCATGTTGAAGAACAGATAATAACGCCTGATGGTGTTGTTGCTGGCAGTCACTTTGGCACTTATGCACCTTTAAAATTTAGTGTCTCACAATTGGATACACatgaaataattattgaaaccagtcgataa
Protein Sequence: MASREEFEETMPINGVVAMYTCKRCNKIFPCKRDQLLHKKEVHSQTKSSYECKICSKYFCNSGNLERHMKVHNDVRPFVCRICGKAFAQSVNLNRHYSVHNGERPYPCTFCNKTFTQQSNMQRHQLTHTGEKPFRCKRCGRYFSQRVNLKKHIMGHLNTKPYTCKICQKSFIQLGNFKKHLQSHLKDGIEIDMKALVAEAQAMAKQSLEMADEQPVGFECAVCRSIFNNFTDFEMHESECNDNAQAAMEQKYNPDEQLHEVVVEEVEDHVEEQIITPDGVVAGSHFGTYAPLKFSVSQLDTHEIIIETSR

Sequence clustering based on sequence similarity using MMseqs2