Basic Information

Insect: Lucilia cuprina
Gene Symbol: L_1
Assembly: GCA_001187945.1
Location: JRES01001421.1:359100-371548[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 4.8e-06 0.00032 20.7 1.7 1 23 247 269 247 269 0.98

2 19 0.38 25 5.3 5.7 1 23 275 297 275 297 0.98

3 19 2.1e-07 1.4e-05 25.0 3.1 1 23 303 325 303 325 0.99

4 19 9.6e-06 0.00064 19.7 0.3 1 23 331 353 331 353 0.98

5 19 2.3 1.6e+02 2.8 0.8 2 23 418 441 417 441 0.85

6 19 0.0019 0.13 12.5 0.2 2 23 468 490 467 490 0.96

7 19 0.025 1.7 9.0 0.7 1 23 591 613 591 613 0.97

8 19 0.28 18 5.7 2.0 2 23 621 642 620 642 0.95

9 19 0.00044 0.029 14.5 0.4 1 23 650 674 650 674 0.93

10 19 0.2 13 6.2 0.1 1 19 679 697 679 699 0.93

11 19 4.9 3.3e+02 1.8 0.5 3 23 711 732 709 732 0.84

12 19 0.0012 0.083 13.1 2.9 1 23 771 793 771 794 0.96

13 19 2.7 1.8e+02 2.6 0.9 1 23 964 988 964 988 0.89

14 19 0.00072 0.048 13.8 4.8 2 23 997 1019 996 1019 0.97

15 19 0.1 7 7.0 0.1 1 23 1025 1047 1025 1047 0.92

16 19 0.009 0.6 10.4 0.4 2 23 1055 1076 1054 1076 0.96

17 19 0.68 45 4.5 0.5 2 23 1166 1187 1166 1187 0.94

18 19 0.0015 0.1 12.8 0.0 1 23 1197 1219 1197 1219 0.97

19 19 0.039 2.6 8.4 0.6 1 23 1226 1248 1226 1248 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	4.8e-06	0.00032	20.7	1.7	1	23	247	269	247	269	0.98
2	19	0.38	25	5.3	5.7	1	23	275	297	275	297	0.98
3	19	2.1e-07	1.4e-05	25.0	3.1	1	23	303	325	303	325	0.99
4	19	9.6e-06	0.00064	19.7	0.3	1	23	331	353	331	353	0.98
5	19	2.3	1.6e+02	2.8	0.8	2	23	418	441	417	441	0.85
6	19	0.0019	0.13	12.5	0.2	2	23	468	490	467	490	0.96
7	19	0.025	1.7	9.0	0.7	1	23	591	613	591	613	0.97
8	19	0.28	18	5.7	2.0	2	23	621	642	620	642	0.95
9	19	0.00044	0.029	14.5	0.4	1	23	650	674	650	674	0.93
10	19	0.2	13	6.2	0.1	1	19	679	697	679	699	0.93
11	19	4.9	3.3e+02	1.8	0.5	3	23	711	732	709	732	0.84
12	19	0.0012	0.083	13.1	2.9	1	23	771	793	771	794	0.96
13	19	2.7	1.8e+02	2.6	0.9	1	23	964	988	964	988	0.89
14	19	0.00072	0.048	13.8	4.8	2	23	997	1019	996	1019	0.97
15	19	0.1	7	7.0	0.1	1	23	1025	1047	1025	1047	0.92
16	19	0.009	0.6	10.4	0.4	2	23	1055	1076	1054	1076	0.96
17	19	0.68	45	4.5	0.5	2	23	1166	1187	1166	1187	0.94
18	19	0.0015	0.1	12.8	0.0	1	23	1197	1219	1197	1219	0.97
19	19	0.039	2.6	8.4	0.6	1	23	1226	1248	1226	1248	0.95

Sequence Information

Coding Sequence: ATGATggctttaaaaatgttataccGTGGGCCTAGTTCaagattagaaaatttaattgaaaaaattcaagCCACCAAGGAAATTGTTAATGCCgacatGTACTCGACACATACATCGTCAAGTTATTCACCTTCAATATCAGATGGTACTATGACACCAAATTCTttacatcatcatcaacatcaccaTCATCAGCAGCATTTAGTTATACCACCGCATTTACCCTTTCCCAATACGGCTGCTTATGAGGAAGACAACAACACAACATCTTCGTTGGCCCTACAGACACAACGTCTGCACAGACAACAAAAAACCAATGGCACTTTGGATGGCGCTGACTATGAAGACAACGCCAATGACAATGACAACGACCACAACAACGAAAGGATTCACAAAAATGATACAAAATTGTGTGAAGACAACAACGACGATACAATTGTTGCAGACAACAAGTCAACCGCAAATATTCACGAAAGTGTCGATGAacagcatcagcagcagcatcaacatcatcaacTTAAACGTCATGGTCGTCATCATCGTTATGCTGAACATGCCTTAAGAATTCCTTCAAAATTACGTAAAATCGATAGGGATTCAGCGGTTGGTAATGGTGCTACTACTACAACTGCTGGTGGTGGTGTTGTTGGAGGTGTAACAACAAACGCAGTCAAGTTTGATAAGTTGACAGGAGATGGTATTAAAAGTGGTAACAATGCTGCCAGTGCCGACGGATCCTATCAATGTCAATTCTGTGATAAATCATTTCCGCGTCTTGGTTATTTGAAAAAACATGAACAGaGTCATGCTGAACACTTGCCCTTTAAATGTGAATACTGTGCCCGTCTCTTTAAGCACAAACGTTCTCGTGATCGTCATACTAAATTGCATACTGGCGATCGTCGTTATCGTTGTCCTCATTGTGAAGCCGCTTTCTCAAgaagCGATCACTTAAAGATCCATATGAAAACTCATGATAACCAAAAACCATTTCAATGTACCATTTGCAATCGAGGCTACAATACGGCGGCCGCTCTTACATCGCACAtgcaaaatcataaaaaacaagCTGCTCTTCTAGCTGCAGGTGGTAATCCTCAAGCTCTTAATTACAGTCCTCGTTCTACGGGATCGGCTTCTAGCAATGGTAGTTTACAGAAACGGCGTTACGGTTTAGCAACAGCCTCCGAACAAAGTCCAAATCGTCTTGACTATCCAAAACGAGGTCGTTCCTCTTCGTCGAATATGCTTAAATGTACATTCTGCTCAAAGTCCGATTTTACTGCCGTTGAACAGTTAAACAATCATCTCCAAACTCAACATGAAAAAGAATTGGCTCATTCTATGACTCCTCCTTCCACAAACAATAATCAAGCGTTAGACAATCACGCCTTCCAGCTGTCGTGTGAATATTGCACTATGAAGTTTCCCAATATCGCTGCCATGTTTCAGCATATGCGCTCAGCCCATTTGGATCGTTTGACCAGTCCTAATTCATACTTTGAACATTTTAATCGTTTAGCGGCCTCGGGCACCTTTAGTCCACGTTTATTAACAGGACCTCCTTTAAGAAGTGCAGCCAGTGCCGAGGAGAACAGCATTAAAGAAGAACACAATTTGTCAAGTCCTAAATCAGTGGAAGCTGTTACACGTCAAAGTGAGGATGAACCTACCGATCTAAGCCAAAATAATCGCAGATCCATGACACCTACAAATACTCCTCAAAATTCCCCACAAGAAAATTTCTCCACAAACGAAAAACCAGGTTTATTCTTCTGCAATCAATGTAATGCTGGTTTACCCGATTTCGAATCATTTCGCAATCATTTGAAAACCCATATTGCCCAGGGTCTCAATCTAGTGTGTCATCATTGCGGCCTGCTATTGAGAGAACATGCTGAATATGAAAGACATGTTATTTCACATTTCCTAATAACAAATTCTGAGTACAATTGTTCGGGAAACTGCCAAAAGTCTTTTGGAAAGCCGGAGGAATTACAAAAACATCTTTTGGATCAACATGCTATAACAATGTTCAAATGTGGACTTTGCAGTGAAATGTTTGAATCGAAAGTGGCCATACAAGTTCATTTTGCATGCACACACTCCGCGGAAACCAAAATTCTAAGATGCTCTGCCTGCATGGATGTATTTagatcagaaaatgattttaatctGCATGTTAAAACTCGTCATCAAGCGGTAAATAATGCACCAGCTCCAGTAAATTCTTTACAGTGCATGTTTTGTCGTACAGTATGTTCCTCTGATTTGGAAATGCAGTTCCATTTGGCAGCCCATGCTAGACAATTTCGTTGTCCTTCCTGTCCGGAAACTTTCCATGTTGAATTCTTACTCGATCGTCATATGCAAACACATCATGGAGGCTTAGAACGTCCTCCACCACCACCTCCAGCAGCTCAATCTATTTCCGAAGAACACACACCTCCCGTTCCCAATCCTAATGCTATATCTCCCATGAATTCTCTGTATGTGAATGCCCTATTTGGTAAATCACCATTAATGCCGCTGGCaccacaaaataataacaacagtaTATTGGATTATAACATGGCATTTGCCTCACATCTCAATAAGGGTCTATTTCCCAATACCACACCCAACAAGTTTTACAATCCTCTACAAATTGACACAAATGCCATGAAACACTCTGCCCTCATGTACGGTTTGTCACAGAGATATTTCGATACTAACCGCACCGTAATGGAAATgtatcaacaacagcagcagcaacaacaacaacaacatcatcaggaaaataataaaacatcgGGTAACTATTTTATTAGCCCCAAACAACCATCAGTCGGACCTCATGATGTTCATCATCGCACCGAATTGCCTGCTTCGCCCATTAACAATACTGGTTTTAGTTGTGGCATTTGTGAGCGCAACGATTTTCGCACCGAATCAGAAGTTCACTCACATCGCAAGATTGTACACAATCTTAAGACGGGGGTTAGTTTAAAGTGTGCCTACTGCTCGGGCAACTTTAAGTCACGCAGTGAATTGGAGCATCATATGAAAACCTGTCACAATTCTACTGGAAAACACAAATGTTTGATATGTGATGAAATCTTTCCCTCACCAGCCATATTGGCCGAACACAAATTACAACATTCCAAGGTGGGACAATCGGGAAAATGTTCGCACTGCTCCAAGGCATTGGCCGATGTTAGTGCATTTAAGGCTCATCTATCCGAACACAATACAGAAGGTCAAATGCCAGTGCAGTGTATCTGTTGTCGTCAGTCATTACATTCCGAATTTGAGATTGGACTGCATGCCAAatttcatgttaaaaacTCAACTGTTCAGGAAAATGTTTGTGCTCTTTGCCTAGAGCCCATTAGCAATTCACCCACTGAAGCCAAAGTATGTGAAAAATGCTGTCGCAAGCATAATCTCAATACAAAGTTCAAGCAGCGCGAGCATTTTGAACGTCCCGCTGAACTAAGGCAATACATTGAAAACCGTTGCAATCTTTGCAAAATGATTTTACCACATGCTCAAAAACTTCAAGAACACTTGGTTGAACACACCTTTGCCGGTTGCGAGGATCGAGGCTTCAATTGTTACATCTGTTCGGCAGTTTTTACGGCGCCAAGCGGTCTACTTAATCATATGCTTGAGCATGGTGTTAACTCCAAGCCTTATGATTGTAATTTATGCCCAGAGAAATACTATTTCCGTGCTGAATTAGATCATCATCTAATCGATCATGATTTGAGACAATCGCCCACTGCTGTTAAAAACGAGCAAGAGCAAATGACACCTAAAGAAGATACTTTGACTAGCATGAAACAAGAAAAACCTGCCGAAAGACTAAATGATGTTAAACAGGAAGTAATTGAAACTGATCATAATTCTAATGTGGCCGATGAAGATGAGTACATTGAGGTGGAAAAGGTAAATgagaataacaacaataacaatcagTTGGATGATACAGTGTCTAATAAAACTGAAGAGTCCAAAGAGAAATCAAGTGAACATATCAGAGATGAAAAGGCATAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEIVNADMYSTHTSSSYSPSISDGTMTPNSLHHHQHHHHQQHLVIPPHLPFPNTAAYEEDNNTTSSLALQTQRLHRQQKTNGTLDGADYEDNANDNDNDHNNERIHKNDTKLCEDNNDDTIVADNKSTANIHESVDEQHQQQHQHHQLKRHGRHHRYAEHALRIPSKLRKIDRDSAVGNGATTTTAGGGVVGGVTTNAVKFDKLTGDGIKSGNNAASADGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAALLAAGGNPQALNYSPRSTGSASSNGSLQKRRYGLATASEQSPNRLDYPKRGRSSSSNMLKCTFCSKSDFTAVEQLNNHLQTQHEKELAHSMTPPSTNNNQALDNHAFQLSCEYCTMKFPNIAAMFQHMRSAHLDRLTSPNSYFEHFNRLAASGTFSPRLLTGPPLRSAASAEENSIKEEHNLSSPKSVEAVTRQSEDEPTDLSQNNRRSMTPTNTPQNSPQENFSTNEKPGLFFCNQCNAGLPDFESFRNHLKTHIAQGLNLVCHHCGLLLREHAEYERHVISHFLITNSEYNCSGNCQKSFGKPEELQKHLLDQHAITMFKCGLCSEMFESKVAIQVHFACTHSAETKILRCSACMDVFRSENDFNLHVKTRHQAVNNAPAPVNSLQCMFCRTVCSSDLEMQFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHGGLERPPPPPPAAQSISEEHTPPVPNPNAISPMNSLYVNALFGKSPLMPLAPQNNNNSILDYNMAFASHLNKGLFPNTTPNKFYNPLQIDTNAMKHSALMYGLSQRYFDTNRTVMEMYQQQQQQQQQQHHQENNKTSGNYFISPKQPSVGPHDVHHRTELPASPINNTGFSCGICERNDFRTESEVHSHRKIVHNLKTGVSLKCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSKALADVSAFKAHLSEHNTEGQMPVQCICCRQSLHSEFEIGLHAKFHVKNSTVQENVCALCLEPISNSPTEAKVCEKCCRKHNLNTKFKQREHFERPAELRQYIENRCNLCKMILPHAQKLQEHLVEHTFAGCEDRGFNCYICSAVFTAPSGLLNHMLEHGVNSKPYDCNLCPEKYYFRAELDHHLIDHDLRQSPTAVKNEQEQMTPKEDTLTSMKQEKPAERLNDVKQEVIETDHNSNVADEDEYIEVEKVNENNNNNNQLDDTVSNKTEESKEKSSEHIRDEKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01237143;
90% Identity: iTF_00045671;
80% Identity: -