Basic Information

Gene Symbol
-
Assembly
GCA_018904225.1
Location
JAEIFT010000124.1:211822-214899[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 4.4e-07 2.5e-05 24.5 1.9 1 23 217 240 217 240 0.97
2 17 0.00036 0.02 15.3 0.4 1 23 247 269 247 269 0.98
3 17 0.14 7.8 7.2 0.1 2 23 301 322 300 322 0.95
4 17 0.00081 0.046 14.2 0.7 1 23 406 429 406 429 0.95
5 17 0.081 4.6 7.9 0.5 1 19 436 454 436 457 0.93
6 17 0.092 5.2 7.8 6.2 1 23 466 488 466 488 0.95
7 17 1.2e-05 0.00071 19.9 0.8 1 23 495 518 495 518 0.97
8 17 0.00015 0.0083 16.6 1.4 2 23 526 547 525 547 0.97
9 17 0.005 0.28 11.7 0.1 2 21 574 593 573 594 0.94
10 17 0.0033 0.19 12.3 2.4 1 23 650 673 650 673 0.98
11 17 0.033 1.9 9.1 3.1 1 23 710 733 710 733 0.95
12 17 0.00017 0.0095 16.4 1.6 2 23 767 789 766 789 0.95
13 17 0.00053 0.03 14.8 1.4 1 23 803 825 803 825 0.95
14 17 0.00014 0.0077 16.7 1.2 1 23 831 853 831 853 0.99
15 17 4.3e-07 2.5e-05 24.5 2.6 1 23 859 881 859 881 0.98
16 17 8e-05 0.0046 17.4 2.3 1 23 887 909 887 909 0.96
17 17 4.2e-05 0.0024 18.3 0.6 1 23 915 939 915 939 0.90

Sequence Information

Coding Sequence
ATGAAACTGCCAGTTGTCTGCCGCACTTGCGATGCAAATGCCAGGGACGCGGATAAACTGTTTAATCTGGACACGCCCAGCAAGAAGTATCCAGACAAATCGCTGGCAAATATCCTAAGCGAACTGACCGACATTGATCTCAATGTTTGCTCCGACCAGAACTGGCCACAAAGCCTATGCTTTAGTTGCTCCAAGAAACTGGTGTCAGCCTTTGAATATGTTAAACANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCGGCACCCACTAGCGATTGTTTACTAGAGGCGCCCATGGAACTATGTGCCGAGCAGCATGTAGAAGTTAAAATGGAAACCGAAGATGCAGAAGACTCGGAGGTAGATAATGATATTACCTGCACGGAGTTGCCTGAACTGGCTGCCGAGGAGTATTTAGACAACAAGAGATCCATAGATCCACTGATAATGCTGGAGGCAGTTAAGCAAGAGGTGAAAAATGTGCAGGAGGAGGAGGAAGAACCAGAGGAGGAGACGGCTACACATGATTTTGAAGCGGATTATGAGGATGATGAAGATTCACTGGATAATCTGCCCTTGCAAAGTCGTGTGCAAAAGTGGAAACAAGGCAACAATAAGAATCAGAAACCTAATTTCCAGTGTGGCGATTGCCCTAAAAGCTTTAAACGCGCCGAGCACTTGAAACAACATCAAGCACGCACTCACAGCAGTAACCGCTCCCTGTTCTCCTGTTCGCTTTGCATACGCAAATTTAGTCGCCCAGAGGCACTGCAGTCTCATCTCAAAGTGCATCGTGACTCCAAGCGCTCTACCAATATAAGTGAGCACAAGAAGGCCAAGGCCATAGATGTGAATCTATGCAAACCTCATGGTTATAAGCTCATAGAGTGCATGATCTGTCAGGGACAATACAATAAAATAGCTGATCTACGACGGCATTTGAAGGAGCATCCGGAAATTGTAACACTGGCTGGACGTCCCAATATGGAGCTGCAGGAGCTGGCCGAACTCTTTTATCCCGATGCCAAAAATGCTAGCGAAGAGCAATTAAAGCAATTAATACGCAAGGATTTGTCTAGTGGCAACTATCAACGTTTCTATTCCATAACCAATCAATCGGGCTATGAAATGGATTTGGATAGCTCGGAAACGGAGAGTGAACCAGAAGCGGAAGATGAACAGCTTAGTTCCCCTGTCAAATACAAGTGTGAACTATGCCAGCAGGGATATCCAAGAAAGTATCAACTGTATGAACATCAAAGTCAAGCACATGCCTGGCTAGAGGCTCCTCATGTGTGTGGACGCTGTGATGCGAGATTTGTTAGCCTGCAGCTGTTAAGACATCACAATGAGTCACAGTGTCGCAATGCACAAAAACGTTTCCTGTGCCACAAATGTCCGCTACGTTTTCGTTGGAAACACAATCTCAGGTCGCATTTTCGAGAGCATCGAATTACGAACCAAATCTATGAGTGTACGGATTGCAAGCGTGTATTTGACAAAAAGAAATCCCTAACTGTCCATTTGCTCAGTGTACATGCCGAGGAATCTAATTTAATGCCTTGCCAGTGGTGCAGTCGAAAGTTTTATCGCCGTGACTATTTGGTGAAGCATTTGAAACGTCATGGCTTACGTGAGCAGGATATACCGCTGGCTGAAACCTTAATAGCCGCCACCTCCAAGCCACATGGAGCTAAAAGCATTTATTGTAAGATTTGTAATCTACAATTTGAACGCATTCAGGAGCTACGTGCTCACATTCAAATGGAGTTAAAACTATCGCTGTCATCTTCGTCAACGCTGCATCAGAATTACGATTCGTTGCTTAACTATTCTATAACCAATGAATCAGGTTTTGAGCTACAGCTGGGCGATTCAGAGACTGAGGATGAAATGCCCACAATAATGGGTTCAACAGGTCAACGTTTGATATATATTTGTGAGCTTTGTAGCGTACAATGTAGGCGTAAATATGAAATGATTCAACATCAGCGTACCATGCATCGCTTTGACAAAATGCCGCATGAATGCGACAAGTGCATCTTCAAGTGTGTGACCAAGAGCATTTTGGATCATCATCGTCTGGTGCAATGTGAGAGCCAGGAGAAAAAGTTTTCGTGCAATCATTGCAGCTACAAATTCATGTGGCCCGAGAATCTACAGCAACACATACACCTACTGCATGGCCAGAGTACCAGCGCAAACAGTATGCTACCCTCGACCAGTGAAGACACCAAAGTTCCAGTTAAGCCCACCAGCACAGAGGATGTTGTGGCCATGCTGCAGTGTCCACATTGCGATCGCACTTATCAAATGAAATCGAGGCTTAACAATCATATACGAGATGTTCATGTGAATGGCGATCGTAAGCGCAAAGAGGCCGTTAAACTGTTTCTTTGCTCGCTATGTGGTCGCGAGACCAAATCAGCCGCCTGCCTGGTAACCCATATGCGTCGTCATACCGGCGAGAAGCCATTCAAATGCGATCTTTGTGAAATGGCCTTTCCCCGGCACTCGGAAATGATATCGCATCGTCGCATGCATACGGGCGAGAAGCCCTTCCATTGTACGGTCTGTGGCAAGGATTTTGCTCGCTCCGATAAGCTAAAGAGGCACATGTTGACGCACAGCGGTTTGAAACCGCATGCCTGTACGTATTGTGAGAAGAGTTATCGCCAGGCCAAGGATTTGAAGTTGCATTTGCAGCAGCATACGGGAGAGTGTCCCTTTATATGTGGCACTTGTGGCGAACGTTTCATACAGAGCAGCACACTGGAGAAGCATCGCATGATGCGACGACATTTTGATGAAGTGGAAGTGGCACAAAATTAG
Protein Sequence
MKLPVVCRTCDANARDADKLFNLDTPSKKYPDKSLANILSELTDIDLNVCSDQNWPQSLCFSCSKKLVSAFEYVKXXXXXXXXXXXXXXXXXAPTSDCLLEAPMELCAEQHVEVKMETEDAEDSEVDNDITCTELPELAAEEYLDNKRSIDPLIMLEAVKQEVKNVQEEEEEPEEETATHDFEADYEDDEDSLDNLPLQSRVQKWKQGNNKNQKPNFQCGDCPKSFKRAEHLKQHQARTHSSNRSLFSCSLCIRKFSRPEALQSHLKVHRDSKRSTNISEHKKAKAIDVNLCKPHGYKLIECMICQGQYNKIADLRRHLKEHPEIVTLAGRPNMELQELAELFYPDAKNASEEQLKQLIRKDLSSGNYQRFYSITNQSGYEMDLDSSETESEPEAEDEQLSSPVKYKCELCQQGYPRKYQLYEHQSQAHAWLEAPHVCGRCDARFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLRSHFREHRITNQIYECTDCKRVFDKKKSLTVHLLSVHAEESNLMPCQWCSRKFYRRDYLVKHLKRHGLREQDIPLAETLIAATSKPHGAKSIYCKICNLQFERIQELRAHIQMELKLSLSSSSTLHQNYDSLLNYSITNESGFELQLGDSETEDEMPTIMGSTGQRLIYICELCSVQCRRKYEMIQHQRTMHRFDKMPHECDKCIFKCVTKSILDHHRLVQCESQEKKFSCNHCSYKFMWPENLQQHIHLLHGQSTSANSMLPSTSEDTKVPVKPTSTEDVVAMLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAVKLFLCSLCGRETKSAACLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHACTYCEKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQSSTLEKHRMMRRHFDEVEVAQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00918346;
90% Identity
-
80% Identity
-