Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.013 78 3.9 0.0 19 46 134 161 124 164 0.89

2 6 0.003 17 6.0 0.1 21 45 164 188 159 191 0.91

3 6 9.6e-05 0.56 10.7 0.4 21 44 192 215 190 219 0.92

4 6 0.0005 2.9 8.5 0.2 21 51 220 250 216 253 0.86

5 6 0.067 3.9e+02 1.6 0.1 21 43 248 270 246 274 0.88

6 6 0.00079 4.6 7.8 1.2 13 48 268 303 264 305 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.013	78	3.9	0.0	19	46	134	161	124	164	0.89
2	6	0.003	17	6.0	0.1	21	45	164	188	159	191	0.91
3	6	9.6e-05	0.56	10.7	0.4	21	44	192	215	190	219	0.92
4	6	0.0005	2.9	8.5	0.2	21	51	220	250	216	253	0.86
5	6	0.067	3.9e+02	1.6	0.1	21	43	248	270	246	274	0.88
6	6	0.00079	4.6	7.8	1.2	13	48	268	303	264	305	0.92

Coding Sequence: ATGAACCAGGAGCGGTCCTGTCGCGTCTGTTTGGCCAACGGAGTTATGTTGGTGCACATATTCAATGAGCCGGAGCAGCTGCAGCGGCAGGAGGAACAATTACCCACTTTGATGGACATGCTGAATGAATTCTGTGAGACAAGACCTGATGATCCCTTGCCATCACATATCTGCCTGAGCTGTGGCTTGGCGGCAGAGAATGCTTTTAGGTTCAAGCGCAGGTACGAGGAGAGCCAACGTCATTTCTATCAGTTATTGTCCCTGGACGGTGGCTTACAAAGCGAAGCTCAAAACGAAACGCACATCGATGTGAGTTGTGTGAAAATAGAAacggaggagcagcagcagcagcctagATACCACATCATTACAGAGGATCCCTTGCTACAACCCCTGCCCAGCCAGAGTATGATGGGCTTCCAGTGTCCCTATTGTCCACAAATGTTCACTCTCAATCACAATCTCAAGGCTCACATACGCATTCACACGGGTGAACGTCCCTTCAAGTGTCCAGAGTGCGGGCAAACCTTTACCCAAAATCAGCATCTCACCAAGCATCTGCGCTGGCATACAGGAGAAAAGCCCTACAGTTGTCCGCACTGTGCGCAATCCTTTGGCCAAAGTCAGCACCTGCAACGGCATATACGAACGCATACAGGCGAACGACCCTACAAGTGTCCACACTGCCCATCGGCCTTTCTGGCCAGTGAGAATCTCAAGACCCATATACGCATACACACGGGCGAAAAGCCCTTCAAGTGTAACTACTGTGACAAGGCCTTTGCCGATAATAATAACCTAAAGAAACATCGGCGACGCCATACCGGCGAACGACCCTTTAACTGTCCACACTGTCCCAAGGATTTCAAGGAACGGCATCACTTAAAAGCGCATGTAGCGGTGAAGCATCGGGATATCGGGGAGCAACAAGTGGAAACACTGCCCACTGCACAGGACCTGTTGGAGTGTGAATATGCTAATGATTTAAGTTTAGTAGAAACTGTgttgaattaa
Protein Sequence: MNQERSCRVCLANGVMLVHIFNEPEQLQRQEEQLPTLMDMLNEFCETRPDDPLPSHICLSCGLAAENAFRFKRRYEESQRHFYQLLSLDGGLQSEAQNETHIDVSCVKIETEEQQQQPRYHIITEDPLLQPLPSQSMMGFQCPYCPQMFTLNHNLKAHIRIHTGERPFKCPECGQTFTQNQHLTKHLRWHTGEKPYSCPHCAQSFGQSQHLQRHIRTHTGERPYKCPHCPSAFLASENLKTHIRIHTGEKPFKCNYCDKAFADNNNLKKHRRRHTGERPFNCPHCPKDFKERHHLKAHVAVKHRDIGEQQVETLPTAQDLLECEYANDLSLVETVLN

Sequence clustering based on sequence similarity using MMseqs2