Basic Information

Gene Symbol
-
Assembly
GCA_035044985.1
Location
JAWNNO010002742.1:399331-402269[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 2.3e-07 1.5e-05 25.6 1.4 1 23 206 228 206 228 0.98
2 16 0.023 1.4 9.8 0.1 2 23 260 281 259 281 0.97
3 16 0.0028 0.18 12.7 0.7 1 23 359 382 359 382 0.96
4 16 0.021 1.4 9.9 0.7 1 19 389 407 389 410 0.92
5 16 0.011 0.7 10.8 2.1 1 23 419 441 419 441 0.97
6 16 0.0013 0.085 13.7 5.1 1 23 448 471 448 471 0.93
7 16 6.7e-05 0.0043 17.8 1.4 2 23 479 500 478 500 0.96
8 16 0.0048 0.31 11.9 0.1 2 21 527 546 526 547 0.94
9 16 0.0021 0.13 13.1 2.3 1 23 603 626 603 626 0.98
10 16 0.17 11 7.1 2.7 1 23 663 686 663 686 0.95
11 16 0.00018 0.011 16.5 1.6 2 23 716 738 715 738 0.95
12 16 0.00076 0.048 14.5 2.0 1 23 752 774 752 774 0.95
13 16 0.00023 0.015 16.1 0.8 1 23 780 802 780 802 0.99
14 16 6.5e-07 4.2e-05 24.1 1.8 1 23 808 830 808 830 0.98
15 16 8.4e-05 0.0054 17.5 2.3 1 23 836 858 836 858 0.96
16 16 0.00013 0.0086 16.8 0.5 1 23 864 888 864 888 0.90

Sequence Information

Coding Sequence
ATGGACATGAAACTAAAATTACCCGGAGTGTGTCGCACTTGCGATGCAAGTGCCAGGGGGGCGAGAAAGCTGCTCAATCTGGACACGCCCAGCAAGGAGTTCCCAGACAAATCGCTGGCGACTATTCTCAGCGAACTGACCCATATCGATCTGCAAGTACCCTTTGCTGAGAAATTGCCGCAATGCCTGTGCACCAGTTGCTCCAAAAGACTTGTGTCGGCCTTTGAATTTGTGAAACAGGCTTTGGCTGCCAATGATTTGTTGATGGAGCATCTTAAAAAGTCAACGTCCAGCAGTGATTGTTTGCTGGAGACGCCCATGGAGCTATGCGCTGATTTACATCTAGAGCTAAAAATGGAAACGGAAGATGAAGAAGATTCTGTGGTAATCAAAGATATAACCTGCACCGAACTGCCCGAGTTGTCTGTTAAGAATTCGGTAGATCCCTTGATAAAGCTGGTGACCATAAAGCAGGAACCAAACGTTTCAGAGGAAGACCCTGATTACGACACACAAGACTCGGAGACGGATGACGAAGATTCTGTGGACTATCAGCCTAGGGAGAAGCGAGCATCAAATCGAAACCAAAGCGTCATCAAAGAGCAAAAACGCAAATTCCAGTGCGCCGAGTGTCCAAAAAGCTTTAAGCGTGCCGCCCACCTAAAACAGCATCTGAAAGTTCATGCCGATCCCAAGCCACCGGCCAGTGTCAGTGAACACAAAAAGGCCAAAGCCATTGATCTCAATCTGTGCAAGCCTCATGGCTACAAGCTCATCGAGTGTTTGATATGTCAGAATCAATTCAGTAAAATTGCAGATCTTCGCCTTCATCTGGAAACACATCCGGAAGTTGTTACACTGGCAGGGCAGGAGCCGGCAGAGTTGGCCAAACTGTTCTATCCCAATGCCAAGGATGTCAGTGAGGAAGAACTGAGACAACTGATACGCAAAGATTTGTCAAGTGGCCTATATCAAAATTTCTATTCCATAACCAATCAACATGGATATGAGATGGGACTGGACAGCTCGGAGACGGAATGCGAGTCAGAAACTAAGGAGGAACCACAAGTCAAATACAACTGTGAGCTGTGCCGGCAGGGATATGCGAGAAAGTATCAGCTTTACGATCACCAAAATCAAGCACATTCCTGGCTAGATGCTCCCCATGTCTGTGGCCGTTGTGATGCACGATTCGTTAGCCAACAGCTGCTCAGACATCACAATGAGACGCTGTGCCGCAATGTTCAGAAACGTTTCCACTGCCTCAAGTGTCCGCTACGCTTTCGCTGGAAGCAAAATCTCAGGGCTCATGTCCGAGAGCACCGGAAAAATATCCAACTCCATGAGTGCCACCACTGCAAAAGTGTCTTTCGCAATAAAAAATCTCTTACCATTCATCTGCTCGGTGTGCATGCCGAAGACTCCACTGTGCTGCCGTGCCAGTGGTGTAATCGCAAGTTCTTCCGTCAAGACTATCTGGTTAAGCATCTGAAACGTCATGGCTTAAGAGAACAGGACATTCCACTGGCCGAAACCATAATAGCGGCCACCTCCAAACCTAATGGAGTCAAGCGGATTAGCTGCAAAGTCTGTAATCTGCAGTTTGAGCGTATCTACGATCTGCGTGCTCACATACAGCAAGAGCTGATGATATCGAAGTCTTCATTGGCCTGCTCGCTGCATCAAAACTACGACTCGCTACTTAACTATTCCATAACCAATGAATCCGGCTTCGAACTGCAATTGGGAGATTCAGAGACGGAGGATGAAATGTCGGTTAACGGTATGGGACAGGCCCAATTGGCATACATCTGCGAGCTGTGTAGTCTTCAGTGCCGGCGTAAGTACGAAATGATACAGCACCAGCGGACTGTGCATTGCTTTGACAAGATGCCGCATGAGTGCGACAAGTGTATCTTCAAGTGTGTGTCCAAGAGCATCATGGATTATCACCGGCTAGCTCAATGTGGCAGCTTGGAGAAAAAACATTCGTGCAGTCATTGCAGCTATAAATACATGTGGCCCGAGAATCTGGAGCAGCACATAAAACTACAGCATGGTCAGTTAACAACGACAACCACTGGAGAACAGCTGTCAACCAGTGAAAACTTGGCCGGGCAAATCAAGGAAGCGGCGTCTGTACTCCAGTGTCCGCACTGCGATCGCACTTATCAAATGAAATCGAGACTCAACAACCATATACGGGATGTTCATGTTAATGGCGATCGCAAGCGTAAGGATGCCGTCAAGTTGTTTCTCTGCTCGCTGTGTGGTTACAAGACCAATACTTCATACCAATTGCTTACCCATACGCGTCGTCATACAGGCGAAAAACCTTTTAAATGTGATCTGTGCGAAGCTGCCTTTCCCCGGCACTCGGAAATGATATCGCATCGGCGCATGCATACTGGCGAGAAGCCCTTCCATTGCACTGTCTGTGGCAAGGATTTTGCACGAGCAGAGAAGCTGAAGAGGCACATGTTGACGCACAGCGGTTTAAAACCGCATGCCTGTACCTACTGCGAGAAGAGTTATCGTCAGGCCAAGGATCTGAAGCTGCATCTGCAGCAGCACACGGGCGAATGTCCCTTCATCTGTGGCTCTTGCGGGGAAAGATTCATACAGAGCAGCACACTGGAGAAGCATCGCATGATGCGACGCCATTTTGACGAAGTGGAAGTTGCTCAAAATTAG
Protein Sequence
MDMKLKLPGVCRTCDASARGARKLLNLDTPSKEFPDKSLATILSELTHIDLQVPFAEKLPQCLCTSCSKRLVSAFEFVKQALAANDLLMEHLKKSTSSSDCLLETPMELCADLHLELKMETEDEEDSVVIKDITCTELPELSVKNSVDPLIKLVTIKQEPNVSEEDPDYDTQDSETDDEDSVDYQPREKRASNRNQSVIKEQKRKFQCAECPKSFKRAAHLKQHLKVHADPKPPASVSEHKKAKAIDLNLCKPHGYKLIECLICQNQFSKIADLRLHLETHPEVVTLAGQEPAELAKLFYPNAKDVSEEELRQLIRKDLSSGLYQNFYSITNQHGYEMGLDSSETECESETKEEPQVKYNCELCRQGYARKYQLYDHQNQAHSWLDAPHVCGRCDARFVSQQLLRHHNETLCRNVQKRFHCLKCPLRFRWKQNLRAHVREHRKNIQLHECHHCKSVFRNKKSLTIHLLGVHAEDSTVLPCQWCNRKFFRQDYLVKHLKRHGLREQDIPLAETIIAATSKPNGVKRISCKVCNLQFERIYDLRAHIQQELMISKSSLACSLHQNYDSLLNYSITNESGFELQLGDSETEDEMSVNGMGQAQLAYICELCSLQCRRKYEMIQHQRTVHCFDKMPHECDKCIFKCVSKSIMDYHRLAQCGSLEKKHSCSHCSYKYMWPENLEQHIKLQHGQLTTTTTGEQLSTSENLAGQIKEAASVLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKDAVKLFLCSLCGYKTNTSYQLLTHTRRHTGEKPFKCDLCEAAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARAEKLKRHMLTHSGLKPHACTYCEKSYRQAKDLKLHLQQHTGECPFICGSCGERFIQSSTLEKHRMMRRHFDEVEVAQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00915511;
90% Identity
iTF_00916495;
80% Identity
-