Basic Information

Gene Symbol
sba
Assembly
GCA_018904265.1
Location
JAEIFV010000015.1:529378-539540[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.4e-11 2.6e-07 30.4 0.1 2 59 43 91 42 113 0.81

Sequence Information

Coding Sequence
ATGGCTGCCGCATCCGCTGGCCAGCAACAGCAACAACATAAATTAAATATTGTTGCTAATAACAATCAGCTTTATGCTAAGAATGTGGCCAAAGTCAACAATCAAGCCAACAACAACATCAACATCAGGCGCAACACTAGCTACAATGGAAATTTGGCTCCAGGCTGGCGTCGTCTAACAAGCAACAATGAAGTGGCCTACATCAGCCCCACGGGTAAAACGCTGCGCACGCAATACCAAATCAAGGACTATTTGCTAACACAGGGTACCTGTAAATGCGGTCTACCCTGTCCGCTGCGACCGGAATATATTTTCGACTTCAATGCACAGGTAAGAAGATAG
Protein Sequence
MAAASAGQQQQQHKLNIVANNNQLYAKNVAKVNNQANNNINIRRNTSYNGNLAPGWRRLTSNNEVAYISPTGKTLRTQYQIKDYLLTQGTCKCGLPCPLRPEYIFDFNAQVRR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-