Basic Information

Gene Symbol
-
Assembly
GCA_018904275.1
Location
JAEIGQ010000144.1:329472-335948[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00054 0.028 15.0 5.6 1 23 171 193 171 193 0.97
2 15 0.0036 0.18 12.4 3.3 1 23 229 252 229 252 0.96
3 15 0.00035 0.018 15.6 2.7 1 23 302 325 302 325 0.96
4 15 0.0038 0.2 12.3 0.4 2 23 381 402 380 402 0.97
5 15 6.1 3.1e+02 2.2 0.7 1 19 517 535 517 537 0.76
6 15 0.023 1.2 9.9 0.7 1 23 547 569 547 569 0.94
7 15 0.00027 0.014 16.0 0.7 1 23 576 599 576 599 0.96
8 15 0.00062 0.032 14.8 0.9 2 23 608 629 607 629 0.96
9 15 0.0084 0.43 11.2 0.6 2 20 656 674 655 679 0.91
10 15 0.0013 0.064 13.8 1.6 1 23 718 741 718 741 0.96
11 15 0.035 1.8 9.3 1.5 1 23 778 801 778 801 0.95
12 15 8.1e-05 0.0041 17.6 0.5 1 23 835 858 835 858 0.96
13 15 0.14 7.1 7.4 0.2 1 23 868 890 868 890 0.94
14 15 0.00032 0.016 15.7 3.6 1 23 896 918 896 918 0.99
15 15 9.6e-06 0.00049 20.5 3.2 1 23 924 946 924 946 0.98

Sequence Information

Coding Sequence
ATGACCAGAACCTGTAGAATCTGCGCTAGCAGTGAGGGGCGGTTTTGGATTGAAACGCCTGTGGAGAAATATGCAGATAAGACCTTCAATCAGCTGCTAATGGAGCTGACACAGTTGGATGTATCGTTGTCGCAGTCAGATAAGCTACCGCCTTGGATATGTCGTAGTTGTGCACAGAAATTGCAGAATTCCTATGACTTTGTGCTGCAAGCCAGGGAGACACACGAAATGTGGCTACAAAAGACACAGTTAGACGACGGGAACGGCGAGAAAGACGAGGACGAGTTTGATATGGACACCTGCCTGCGTGAAACTCCCATTCAACTGTTGGAGATTGAGGGTGTTACCATTAAAATGGAGGAACCAGAACCAGCCGCTACAGCTGTGGGATCTGCTCCTGATCCCCTGGTGCGTGCACGCCTAGCCCATTTTAGTGATACAGAGGATGAGGATGATGTGCCCCTGCAGCAGCGTTGCTCCGCAAAGCCAGTACTTGTCCAACCGAAGCCACACAAATGTAATCTCTGTAACAAATCGTTTAGATATATCACCAATCTGTATAGGCACAAGAAAGAACACAACTTTACCGAGAAGGCGGAACCTTTTCTGCATCGTGTAATCAAAAGTGCGGTGGCTGCCAGAGGCAACACCAAAGCGGATGCCGATGATGGTGAGGATAACTACTATAAATGCGATCAGTGTGACAAATCCTACAAGTACATCATGCTGCTGGTCAAGCACAAGCATAAGGTTCATGGTGGAAGCCAATTGCCTGGGACAGCCAGACTCACACGCCCTGCTCCCGACCAGCGACCGAAGCTGAGCACGGATACCCTAGTGCACAGCCTCATCCAGGCTGTGGAGATATCTGATGAGGATGGCAACTCCAGTTCGGATAATTATTACAAGTGCGATGAATGCGATAAATCCTACAAATACATAGTCAGCCTCATCAAGCACAAGCATAAGGAACATTCCGATTTGGCCAAAGATGCCATGTCAACTGCCCCTGGCCTCGACCATTCTCTGCCCTCGACTTCCGCTTCGGCTGGCATTGCCAATCCAAAGCCCTCGCGCATCAATCGTCGTGTTCAGGGCTTCGATTTGTATCGTTGCCAGCCCAATGGCTCCAAGGAGATTCAGTGTATGATTTGTCTGCGTCGCTTTGCCAAATTGGGCGAATTACGCTCCCATCTCAAGTACCATCCCAAAGATTTTGATTTTCAGGCTCATGGTGAACCCATAGAGCGCATAGCTGAGGGCTTCTTCAAGACGGCCGTGGAGTCCACCGTGGATGGTCTAAAGCGTCGCATTCTTAATGACCTCAGAGAGGGCGTTTATGGACGCTACTATTCCATTACCAATCAGTCACGCTACGAGATGAGTCTGGACAGCTCGGATACGGATAGCGATGGTGATGAAGCCGCCGAAGTGGTGTTGCGTCGTAGCTATGCCTGTGAGCTGTGCGACAAGCCAGAAGCAAAATGGCCACGAAAATATCAGCTCCATGAGCATCACCGACAATGTCATACGTGGATGGAGGCACCGTATGTGTGTCGCCGTTGCGATTCTCGATTTCTGAGTGAACAATTGCTGGAGCATCACACTAGTCAATTATGTCAGAACACACTTAAGCGATTCATGTGCGACAAGTGTCCGCAGCGTTTCTTTTGGCGCAAGAATCTGCGGGCCCACTTGGTGGAGCACAAGGATAAGCAAGAAAACTATCCCTGCGACCAATGCCAGCGCAGTTTTCAGGACAAAAGCGCCGTGACCAAGCATAAATTGATGATGCATTCAGATGGCAATGGTCAACTTCTACCCTGTCGCTGGTGCACTCGTGTGTTTTATCGCCCCGCATTGCTGCACAAGCATGTCCAACGACATGGCTTCAGCGGCCAAGATATACCATTGGCCGAGACACTGCTTGCGGATGCCGCCAAACCCTTGGGACCCAAAACCATTCACTGCAAGCTATGTGACATTCAGTTCATCAGTATAGCAGACTTGCGCCGTCACATGGTCCACATGGGCCATGACCATCGGTCAACCAACTACATGATCAGCACAGAGGCGGGCTTTGAACTACAATTGGAGGACACGGATGACAGCGACGATGGTGGGGAAGATGCTGACCATGTCAGAAGATCCTATACCTGTGATCTCTGTCAGATGAGCTTCCGACGCCGGCGGGACATGAGTGAGCATCAGTATTCTTTGCATACTTTTGATAAATTGCCACATAACTGCGAGCATTGCATTTACAAGAGTGTGGACAGGCTTATGCTGGAACACCATTTGCGATCTCAATGCTGCAACCAGGAAAAGAAATTTATTTGTTCGCATTGTGGCTATAAGTTCATGTGGCAGCAGAATCTCGATCAGCATTTGGTCACTCAGCATCCCCAACCAAATAGCAGCCAGGAGCAACTACAGCAGCAGCTGCTCCTGCAACAACAACAACAACACCAAATACCTATACGTCGTCGACGACGCTTCCGTTACCAATGCCCGCACTGCTGGCGCTCGTTTGTCATCCAGCCCAGTTTAGATAAACATATACGGGACATGCATGTGGCCAAAAAGAATCCGGGCAAGAAATATCTGTGCTCGCTGTGCGGCCTGGAGTCGCTTACACCCAACAAACTGAGCATTCATATGCGTCGTCACAATGGCGAAAAGCCCTTCAAATGTGATCTATGTGAAATGCGATTTACGGTCCATTACGAACTGAAGGTCCATCGTAGAAAACATACCGGCGAGCGTCCATATCAATGCACCTTCTGCGACAAGCATTTCGCTCGACCCGATAAATTGAGACGGCATGTCTATATGCACAGTGTCAAGCACTAG
Protein Sequence
MTRTCRICASSEGRFWIETPVEKYADKTFNQLLMELTQLDVSLSQSDKLPPWICRSCAQKLQNSYDFVLQARETHEMWLQKTQLDDGNGEKDEDEFDMDTCLRETPIQLLEIEGVTIKMEEPEPAATAVGSAPDPLVRARLAHFSDTEDEDDVPLQQRCSAKPVLVQPKPHKCNLCNKSFRYITNLYRHKKEHNFTEKAEPFLHRVIKSAVAARGNTKADADDGEDNYYKCDQCDKSYKYIMLLVKHKHKVHGGSQLPGTARLTRPAPDQRPKLSTDTLVHSLIQAVEISDEDGNSSSDNYYKCDECDKSYKYIVSLIKHKHKEHSDLAKDAMSTAPGLDHSLPSTSASAGIANPKPSRINRRVQGFDLYRCQPNGSKEIQCMICLRRFAKLGELRSHLKYHPKDFDFQAHGEPIERIAEGFFKTAVESTVDGLKRRILNDLREGVYGRYYSITNQSRYEMSLDSSDTDSDGDEAAEVVLRRSYACELCDKPEAKWPRKYQLHEHHRQCHTWMEAPYVCRRCDSRFLSEQLLEHHTSQLCQNTLKRFMCDKCPQRFFWRKNLRAHLVEHKDKQENYPCDQCQRSFQDKSAVTKHKLMMHSDGNGQLLPCRWCTRVFYRPALLHKHVQRHGFSGQDIPLAETLLADAAKPLGPKTIHCKLCDIQFISIADLRRHMVHMGHDHRSTNYMISTEAGFELQLEDTDDSDDGGEDADHVRRSYTCDLCQMSFRRRRDMSEHQYSLHTFDKLPHNCEHCIYKSVDRLMLEHHLRSQCCNQEKKFICSHCGYKFMWQQNLDQHLVTQHPQPNSSQEQLQQQLLLQQQQQHQIPIRRRRRFRYQCPHCWRSFVIQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCEMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSVKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00914715;
90% Identity
iTF_00918420;
80% Identity
-