Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.013 72 3.9 0.0 19 46 135 162 125 165 0.89

2 6 0.0018 9.8 6.6 0.1 21 46 165 190 161 196 0.87

3 6 8e-05 0.43 11.0 0.5 21 44 193 216 189 220 0.91

4 6 0.0005 2.7 8.4 0.2 21 51 221 251 217 254 0.86

5 6 0.065 3.5e+02 1.7 0.1 21 43 249 271 246 275 0.89

6 6 0.00077 4.1 7.8 1.2 13 48 269 304 264 306 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.013	72	3.9	0.0	19	46	135	162	125	165	0.89
2	6	0.0018	9.8	6.6	0.1	21	46	165	190	161	196	0.87
3	6	8e-05	0.43	11.0	0.5	21	44	193	216	189	220	0.91
4	6	0.0005	2.7	8.4	0.2	21	51	221	251	217	254	0.86
5	6	0.065	3.5e+02	1.7	0.1	21	43	249	271	246	275	0.89
6	6	0.00077	4.1	7.8	1.2	13	48	269	304	264	306	0.92

Coding Sequence: ATGAACCAGGAGCGGGCCTGTCGCGTCTGTTTGGCCAACGGCGTTATGTTGGTGCACATATTCAATGAGCCGGAGCAGCTACAGCGGCAGGAGGAACACTTACCCACTTTGATGGACATGCTGAATGAATTCTGTGAGACAAGGCCAGATGATCCCTTGCCGTCACACATCTGTTTGAGCTGTGCCTTGGCGGCAGAGAATGCTTTTAGATTCAAGCGCAGGTACGAGGAGAGCCAACGTCATTTCTATCAGCTAATGTCCCTGCAAGGTGGCTTACAAAGCGAAGCTCAACCCGAGACACACATCGATGTGAGTTGTGTGAAAATAGAATcggatgagcagcagcagcagcagcctagATACCACATCATTACAGAGGATCCCTTGCTGCAACCCCTGCCCAGCCAGAGTATGATGGGTTTCCAGTGTCCCTATTGTCCACAAATGTTCACTCTCAATCACAATCTCAAAGCTCACATACGCATTCACACGGGTGAACGTCCCTTCAAGTGTCCCGAGTGCGGGCAAACCTTTACCCAAAATCAGCATCTCACCAAGCATCTGCGCTGGCATACAGGAGAGAAGCCCTACAGTTGTCCGCACTGTACGCAATCCTTTGGCCAAAGTCAGCACTTGCAACGACATATACGAACGCATACAGGCGAACGACCCTACAAGTGTCCACACTGCCCATCGGCCTTTCTGGCCAGTGAGAATCTCAAGACCCATATACGTATACACACGGGCGAAAAGCCCTTCAAGTGCAACTACTGTGACAAGGCCTTTGCCGATAATAATAATCTAAAGAAACATCGGCGACGCCATACCGGCGAAAGACCCTTTAATTGTCCACACTGTCCCAAGGATTTCAAGGAACGGCATCACTTAAAAGCCCATGTAGCGGTGAAGCATCGGGATATTGGGGAGCAACAAGTGGAATCACTGCCCACTGCACAGGACCTGTTGGAGTGTGAATATTCTAATGAATTAAGTTTAGTAGAAACTGTGTcgaattaa
Protein Sequence: MNQERACRVCLANGVMLVHIFNEPEQLQRQEEHLPTLMDMLNEFCETRPDDPLPSHICLSCALAAENAFRFKRRYEESQRHFYQLMSLQGGLQSEAQPETHIDVSCVKIESDEQQQQQPRYHIITEDPLLQPLPSQSMMGFQCPYCPQMFTLNHNLKAHIRIHTGERPFKCPECGQTFTQNQHLTKHLRWHTGEKPYSCPHCTQSFGQSQHLQRHIRTHTGERPYKCPHCPSAFLASENLKTHIRIHTGEKPFKCNYCDKAFADNNNLKKHRRRHTGERPFNCPHCPKDFKERHHLKAHVAVKHRDIGEQQVESLPTAQDLLECEYSNELSLVETVSN

Sequence clustering based on sequence similarity using MMseqs2