Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.015 66 4.0 0.5 26 46 168 188 160 190 0.90

2 7 1.6e-07 0.00068 20.0 0.2 22 47 192 217 189 222 0.89

3 7 0.038 1.6e+02 2.7 0.2 23 44 221 242 217 245 0.89

4 7 0.00019 0.82 10.1 0.2 18 47 243 273 239 278 0.84

5 7 0.0066 28 5.2 0.5 21 46 275 300 271 303 0.90

6 7 0.34 1.5e+03 -0.3 0.0 22 45 304 327 300 334 0.85

7 7 0.25 1.1e+03 0.1 0.1 25 44 334 353 323 357 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.015	66	4.0	0.5	26	46	168	188	160	190	0.90
2	7	1.6e-07	0.00068	20.0	0.2	22	47	192	217	189	222	0.89
3	7	0.038	1.6e+02	2.7	0.2	23	44	221	242	217	245	0.89
4	7	0.00019	0.82	10.1	0.2	18	47	243	273	239	278	0.84
5	7	0.0066	28	5.2	0.5	21	46	275	300	271	303	0.90
6	7	0.34	1.5e+03	-0.3	0.0	22	45	304	327	300	334	0.85
7	7	0.25	1.1e+03	0.1	0.1	25	44	334	353	323	357	0.81

Coding Sequence: ATGATGTGCTGTACATCGGAGTGCTCAAGCAGACAACAACAAACTGATGATAATAGTTTGCTGCATGTTAATAGTGATTTCACCGAACAGATAACTGACAATCAGAAACAAAATGGTACAGGAGGAGGCAGTTCAAATCGTCTGCAGGAGTGGGAGGTGTCAGGTGCCCACGATAGTGTGAGGGATCCACTAAGCATTGATGAAGAGGAATGTTCACTTTCAGAAGAATTTCCCTTATCTTCTACAAACAGTATTGTAAAAATAGAGAATATCAAAGATGAGGACATTGAAGAGAGCAATGACTACTCGGAGGAGCTGAAACTGGATGTGGAGTTCACAAATAGTGACAATGAACCAGAAAGCATCACACTGGCTGCGGAGACACACAACAGCATACAATGCTCAACCACACAAGGAACTTCCCATCTTGGGCACAGGTGTGACATCTGCAAAAAGTCGCAGTACCTGAAACAGAATAAGCCCACTGGTAAAGTCTGTCATAGATGTAGTGTTTGCAACATGACATTCATACAACATAATCGCTTGAAGCGCCATTTAATGTTGCACACTGGCGAACTCCCGTATTCCTGTGATATTTGTTACAAGACATTCAGAGCAAGTGAAAACCTGAAGCGACATTATCGTCTACACACTGACGGACGACCCTACACTTGTAACGTTTGCAACAAGACATTCAAGACTAATACTCACTTGAAACAACACATACGGTCACACAGTGGCGAACGACCCTATAGCTGTGACGTATGCAACAAGACATTCACAAAAAAAAGTAATCTGTATCGTCATTTTCGGTTACACACCGGCGAACGTCCCTACAGTTGTCATGTTTGCAACAAGAGATTCAAACAAATTAATAACGTCAAGGAACATATCCGGATACATACTGGCGAATTTCCATACAACTGTAACGTTTGCAACAAGAGATTCGATAAAATTAGTAATGTCAAGGTTCACTTACGGACACATACTGGCGAACATTACTGCTGTAACATTTGCAACAAAACATTCACACAAAAAGAATCACTGAATGAACATATCAGGCAACACACTGGAGGAGACCCTATACCTGTGTGA
Protein Sequence: MAPKFKLLYGAIKGLGEPVRFLLSYGKIEFEDERIDLQQWPSVKESMPFGQVPVLEIDGKKTWQSLAICRYLGNQIGLAGANDWEDLQIDMAVEAVTDLRLKIASFAYENDAAIKENKKAAVVNESLPFLLGRLDNLVKQNRGHLANGKLSWADLYFVALLDYLNFLTGFDLTKDYPNLSALKRTVLEIPAIKEWVTKRPKTDM

Sequence clustering based on sequence similarity using MMseqs2