Lcra024761.1
Basic Information
- Insect
- Lochmaea crataegi
- Gene Symbol
- Zfp42
- Assembly
- GCA_947563755.1
- Location
- OX387430.1:7350378-7351798[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.027 6.3 9.0 1.2 2 23 113 135 112 135 0.96 2 11 0.029 6.7 8.9 0.2 1 23 155 178 155 178 0.97 3 11 0.003 0.71 12.0 1.5 1 23 182 204 182 204 0.99 4 11 0.058 14 8.0 2.6 1 23 210 233 210 233 0.97 5 11 0.0014 0.33 13.0 0.4 1 23 239 261 239 261 0.88 6 11 0.0017 0.39 12.8 2.9 1 23 267 290 267 290 0.96 7 11 0.00024 0.057 15.4 1.1 2 23 302 324 301 324 0.96 8 11 9e-06 0.0021 19.9 1.0 3 23 338 358 336 358 0.96 9 11 1.4e-05 0.0034 19.3 1.4 1 23 364 386 364 386 0.97 10 11 5.7e-07 0.00013 23.7 0.7 1 23 392 414 392 414 0.98 11 11 0.014 3.2 9.9 0.0 1 21 420 440 420 441 0.95
Sequence Information
- Coding Sequence
- ATGAAGGTGGAGGACAAGTTTTACCCTTCGGAGGAGGGAGATATGAAAGTGGACGACAAGTTTTTTCCAGCGGTGGAGGTCGAGATGAAAGTGGACGACAAGATATTTGTAGTTGATAATATTACCCCGCCTTCGAGAAAAGCTAAAGAAATAGCCCCGAGGAAAGTAATAATAAAAATAGAAGAAGACGACGAATTTACAGAAGAAGAATTTAGCGATGAAGATTACACCCCGCCAGGGTATAAGAAAAAGAAAAATAAATGTCCCAAAGAAAAGAAACCACCGAAACCAAGATCCTCCAAAGTTAGAGTCAAAAGACAAGAGCACAAAGTTTGGACTTGTCGAAGATGCTTAGAGGAATTTATGTCGAGGCGTGAACTAACTGACCACACGAAAACCTACCACCCCGAAGAAAACAAAGAAATACAACACACTTTTAAATTCGACGAAGAACAAGAAATATACACTTGTTCCACCTGCTCAGCGGAATACCAAAGCCAAAAAGAAGTAGAAGAACACATTTCGAAAATCCACGAAGAATTCTACACCTGTGAGGTATGCCAACACACAGCGACGAAAGCTTACAAGTTCGCCCTTCATATGAAAATCCACAGTGCGGACGATACGTACACGTGTCCTTTATGTAGCTACAACACACTTAGAAGAACCTGTCTACAGACTCACATAAACAGAGTCCATTACCACAAGTTCTATTACACTTGTCCGACTTGCGGGAAAGGATTCAACGATTCCGTTATATTCAAAGAACATAACAACGAACATTTAGGTATAAAACCATTCGTTTGTGTCGTATGTAATAAGTGTTTTGTTTATTCGAGGTACATGCTGATACACCAGACGAGATACCATACGGTTCACATCGAAGGTACCTTACATAAAACCCAATGTAGCATTTGTCTAAAAGTGTTTAGTAAAGTAACGACCTTGTTAAAACATATTACAACAAAACATAGTGCTAatcctgctgaaaaacccgagaagcgccatctatgcgacatgtgcggaaagggcttcggaacttccgataaattgaaaattcattataggatacatactggagataaaccgttcgcttgtagatattgcgagaaacgatttacgaaaaaggattatcttatcatgcacgaacgtgtccatacgggagagaaaccgtatccttgcatgtactgcgggaaatgtttcaaccaagcggcctctctaaggattcacgttcggggacataccggcgaaagaccttatatatgtcagatttgtaatggggggtatatttctaggggatctttgaatttgcatctgaaaatttgcaacggaatagctATATATGTAGATTTTAGGTTATGTGACAAGGTTACAGACTGA
- Protein Sequence
- MKVEDKFYPSEEGDMKVDDKFFPAVEVEMKVDDKIFVVDNITPPSRKAKEIAPRKVIIKIEEDDEFTEEEFSDEDYTPPGYKKKKNKCPKEKKPPKPRSSKVRVKRQEHKVWTCRRCLEEFMSRRELTDHTKTYHPEENKEIQHTFKFDEEQEIYTCSTCSAEYQSQKEVEEHISKIHEEFYTCEVCQHTATKAYKFALHMKIHSADDTYTCPLCSYNTLRRTCLQTHINRVHYHKFYYTCPTCGKGFNDSVIFKEHNNEHLGIKPFVCVVCNKCFVYSRYMLIHQTRYHTVHIEGTLHKTQCSICLKVFSKVTTLLKHITTKHSANPAEKPEKRHLCDMCGKGFGTSDKLKIHYRIHTGDKPFACRYCEKRFTKKDYLIMHERVHTGEKPYPCMYCGKCFNQAASLRIHVRGHTGERPYICQICNGGYISRGSLNLHLKICNGIAIYVDFRLCDKVTD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00911365; iTF_00736089; iTF_01106653; iTF_00387501; iTF_01047696; iTF_00026319;
- 90% Identity
- iTF_00911365;
- 80% Identity
- -