Lcra010825.1
Basic Information
- Insect
- Lochmaea crataegi
- Gene Symbol
- topi
- Assembly
- GCA_947563755.1
- Location
- OX387422.1:121656340-121660483[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.029 6.7 8.9 3.6 2 21 215 234 214 235 0.94 2 14 1.7e-06 0.00039 22.2 0.8 1 23 260 282 260 282 0.98 3 14 0.04 9.4 8.4 0.2 2 20 289 307 289 309 0.92 4 14 0.17 40 6.5 0.2 2 19 329 346 328 349 0.84 5 14 0.0013 0.31 13.1 0.8 2 23 404 425 403 425 0.97 6 14 1.1 2.6e+02 3.9 0.9 1 12 431 442 431 444 0.89 7 14 0.0088 2.1 10.5 3.1 2 22 468 488 467 491 0.88 8 14 0.019 4.4 9.5 0.1 1 23 590 613 590 613 0.97 9 14 0.0017 0.41 12.7 0.1 1 23 617 639 617 639 0.97 10 14 1.3e-06 0.0003 22.6 2.0 1 23 645 667 645 667 0.98 11 14 0.0018 0.43 12.7 1.1 1 23 673 698 673 698 0.96 12 14 0.21 49 6.2 3.5 1 23 704 726 704 726 0.91 13 14 7e-06 0.0016 20.3 0.6 1 23 732 754 732 754 0.98 14 14 0.00072 0.17 13.9 4.2 1 23 760 783 760 783 0.98
Sequence Information
- Coding Sequence
- ATGAACACCCTTGATAATAACACAATTGTAAACGTATATAAAATAGAAGAAAATGGTACGGCGTCTTCAGGAATGTGGTATGGAAAGAATTCAAGCACCGAAGATCCTATATCTACAAAAGTAGATAGACTAAGACAGTTCCGCGACAAGTATAGGGAAAACAGTGTGTTAGAGAGAGAGAGTTATAAGGCAAATAGAGAATCTCAGTTTATCTGGTGGGGAAGAAGAAGTACGACAGGCGTGGAGCAGTCTTACATGCAGACAATTACCACAAATTACTTATCCGTTAAGACGTATTCAACCATGTTCAATAGAACAGAAGAAGATATAAAAAATGAAATCAATAATGTTTTTGCTATGTCATGTGTAATATTAGTATTTGTCTTTGTTTTAATTTTAAAAATTGTGAAACGAAAATTTGAATCTTCATGTAATATAAAAGTTGATGAATATACAGAGTGTTTCAATAAAAAACCCATCTTTGATCCTGATATATTATTATCTAATGAAAACCGATTAACATTGAATTTAAGCCAATTCAAGAACGATGAATATTTTGTTAAGTGTATTAAATTAGAAGATAGATATGACTCACCATCGATATATGTCGGTAAGACCGTTTTGAATCTTCCTACTATGATAAGATGCCAAAATTGTGAGACTATTTTTCCCACTAAATGTCAATATCAAAGGCATCAGTGTGAATTTAATGCAGAAAAAGCTGTTTTAAAATCGGATGTTGATTCTAGTGAAACTGATGGCGGTATTCCCGTTAAATACATTTGCGAAGTTTGCAATAAACAGTTTGTTAATAAAAATAATTTGGTTCGTCACCAGTCTAGCCACGAAAATACACAAGAAAATGTGTGTGAAAATTGCAACAAACAATTTATTAGTGAAAATCGTTTGAGGATACACAAAGAAAACTATTGTAAAAAAGCTGGAGACATTTCTAAATTTTACAGAAGCGATGTGGCTGTTTGGAAATGCAAAAAGTGTTATGAAGTATTTTCTTCACCTCTATCAGCAAATTATCACGTGACATCTTGTGTAGAAATCGTAGAAATCGAAGAAATCGAAGACGATGAAGCAGAAAAAACAACACAATTATCGGACGAAGGTAAAGTTGTCTTGACTAACGAAAATATTCACACCAAAGAAGCAATTGACAAGAAAAGCATAGAAAAAATATCAACCGAGCTTCTACTACAATGTGAATTTTGTAACAGAACTTACGCCGAAAAAAAGGTTCTGCTTATACACCAAAGGAAACACACTACAGCCAGAAATTACGAATGTGTTGATTGCTTTAAAGTTTTCGATTCTTATCCAATAGCCGCCCAACATTGGATGAAAAAGTGTTCGGAATACGTAAATCTGTTTTGCTTGCCAAAATTAACTTACTGTGAATATTGCGACAGAACATACAAATCTCACGAACTACTCTACACGCACAAAATAAAAAAGAAGCACTATACTCACAAGCTCCAAACTGAAGAAACCAACAAAGATGTCGATGTTACAGTTCCCGAAGATAACAAAAATATCCTCAACAAACTAATCGAGGACGTTTTAGAAACTTTAGACGTCCCAGTTAACAAAATCCACTATCAAGGAACAGACGCAAATAAAGAGAATACCGGCGAACAACTTGAAAATTCTGTTGATACAACGGAAAAGAAGAAGAGAGGTAGAAAACGAAAATGGCCGACAAATCTGAGTGCGAGAACGAAAAAACCGAGTCTTCAAGTCGACGACGGTTATAAATATCAATGCGAAAGGTGCATCGAAACTTTTATAAATGTTGACGATCTTGAGGAACATCGGGAGAAGGTACATGCTTCGAATTTCACTTGTGATGAATGTGGACAGGTTTTGCATAACGCCAAAGCTTTGATAGTACACAGTCGTGCTCATAAGAAGTTAAAACCGTATGTTTGTGAAACTTGCGGCCGAAGCTATTCCCAAACTTCTCATCTTTTGATACATATGCGCTTCCATCAAGGGATAAAGCCGTTTGCGTGCCCTCACGAAGGCTGTGAAGCGAGATACACGATACGTTCGCATTTGAAGGATCATATAAGAAGAGCCCACACTAGAGAGAGACCATTCAAATGCAACGTTTGCGATAAATGTTATTTAACTGGTTCTGTTTATTACCAACACCGTTTGACACATACCAATGACAGAAGATATGCATGTGATCTCTGTCCTAAACGGTTTTTTAGAGCCGAAACTCTCAATAATCACCGAAGGATCCATACCGACGAACGCCCTTTCCCTTGCCATGTATGCCGAAGGCAGTTTAGACAGAAAGTAGATCGTAACAAACATCTTAAGACTCAGCATCCTGTTTCAGTTTAA
- Protein Sequence
- MNTLDNNTIVNVYKIEENGTASSGMWYGKNSSTEDPISTKVDRLRQFRDKYRENSVLERESYKANRESQFIWWGRRSTTGVEQSYMQTITTNYLSVKTYSTMFNRTEEDIKNEINNVFAMSCVILVFVFVLILKIVKRKFESSCNIKVDEYTECFNKKPIFDPDILLSNENRLTLNLSQFKNDEYFVKCIKLEDRYDSPSIYVGKTVLNLPTMIRCQNCETIFPTKCQYQRHQCEFNAEKAVLKSDVDSSETDGGIPVKYICEVCNKQFVNKNNLVRHQSSHENTQENVCENCNKQFISENRLRIHKENYCKKAGDISKFYRSDVAVWKCKKCYEVFSSPLSANYHVTSCVEIVEIEEIEDDEAEKTTQLSDEGKVVLTNENIHTKEAIDKKSIEKISTELLLQCEFCNRTYAEKKVLLIHQRKHTTARNYECVDCFKVFDSYPIAAQHWMKKCSEYVNLFCLPKLTYCEYCDRTYKSHELLYTHKIKKKHYTHKLQTEETNKDVDVTVPEDNKNILNKLIEDVLETLDVPVNKIHYQGTDANKENTGEQLENSVDTTEKKKRGRKRKWPTNLSARTKKPSLQVDDGYKYQCERCIETFINVDDLEEHREKVHASNFTCDECGQVLHNAKALIVHSRAHKKLKPYVCETCGRSYSQTSHLLIHMRFHQGIKPFACPHEGCEARYTIRSHLKDHIRRAHTRERPFKCNVCDKCYLTGSVYYQHRLTHTNDRRYACDLCPKRFFRAETLNNHRRIHTDERPFPCHVCRRQFRQKVDRNKHLKTQHPVSV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00736063;
- 90% Identity
- iTF_00912471;
- 80% Identity
- -