Basic Information

Insect: Lochmaea crataegi
Gene Symbol: Zfy2
Assembly: GCA_947563755.1
Location: OX387423.1:95333369-95335459[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0038 0.88 11.7 1.4 1 23 105 127 105 127 0.98

2 16 2.4 5.6e+02 2.9 0.8 2 23 133 154 133 154 0.90

3 16 0.00074 0.17 13.9 8.3 1 21 160 180 160 182 0.95

4 16 1.7e-06 0.0004 22.2 1.3 1 23 188 210 188 210 0.97

5 16 0.034 7.9 8.7 2.0 1 23 218 240 218 240 0.97

6 16 6.1e-05 0.014 17.3 0.4 2 23 247 268 246 268 0.97

7 16 0.00084 0.2 13.7 0.4 1 23 273 296 273 296 0.97

8 16 0.013 2.9 10.0 7.5 2 23 300 321 299 321 0.96

9 16 2e-05 0.0047 18.8 1.0 1 23 327 350 327 350 0.96

10 16 8.1e-07 0.00019 23.2 0.4 2 23 358 379 358 379 0.98

11 16 8.1e-09 1.9e-06 29.5 1.6 1 23 383 405 383 405 0.99

12 16 2.6e-06 0.00062 21.6 1.5 1 23 411 433 411 433 0.99

13 16 0.00037 0.085 14.9 2.4 1 23 439 461 439 461 0.97

14 16 5.5e-05 0.013 17.5 1.7 1 23 467 489 467 489 0.98

15 16 0.00011 0.027 16.5 5.1 1 23 495 519 495 519 0.92

16 16 0.0024 0.57 12.3 0.5 1 21 526 546 526 549 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0038	0.88	11.7	1.4	1	23	105	127	105	127	0.98
2	16	2.4	5.6e+02	2.9	0.8	2	23	133	154	133	154	0.90
3	16	0.00074	0.17	13.9	8.3	1	21	160	180	160	182	0.95
4	16	1.7e-06	0.0004	22.2	1.3	1	23	188	210	188	210	0.97
5	16	0.034	7.9	8.7	2.0	1	23	218	240	218	240	0.97
6	16	6.1e-05	0.014	17.3	0.4	2	23	247	268	246	268	0.97
7	16	0.00084	0.2	13.7	0.4	1	23	273	296	273	296	0.97
8	16	0.013	2.9	10.0	7.5	2	23	300	321	299	321	0.96
9	16	2e-05	0.0047	18.8	1.0	1	23	327	350	327	350	0.96
10	16	8.1e-07	0.00019	23.2	0.4	2	23	358	379	358	379	0.98
11	16	8.1e-09	1.9e-06	29.5	1.6	1	23	383	405	383	405	0.99
12	16	2.6e-06	0.00062	21.6	1.5	1	23	411	433	411	433	0.99
13	16	0.00037	0.085	14.9	2.4	1	23	439	461	439	461	0.97
14	16	5.5e-05	0.013	17.5	1.7	1	23	467	489	467	489	0.98
15	16	0.00011	0.027	16.5	5.1	1	23	495	519	495	519	0.92
16	16	0.0024	0.57	12.3	0.5	1	21	526	546	526	549	0.87

Sequence Information

Coding Sequence: ATGAAATCGGAATCAAACAATGAACAAGATCAAGTTAACATTAAAAAAGAACCTACCATAGAAAATGAATCCAAACCTGAAGATAATTCTAACGTCGATTTACCTATTCTAAATGTAAAATTAGAACCACCAGAATGTTCTGCAAGCGAGAAAGTTATAAAAATGGAAATAAAACCAGAATTGCCATTGGATTTTGAACCGAACCAGTCTGAGAATATTGTTGATATTCACGAAGAGAATTTAAATATATCTTTTGAAGAACTGAAAGCATTAAACGACGATTTAACTATTATTGATAATGAAACCACCGTTTACAAATGTCAAATATGTGAAGTAGTCTTTATCAAGTATCAGGAATATAGGTTACACAAAAAAAATCATTATATTGAGAAAAGAAGATGTTATATTTGCCATAAAGTTCAGCAGAGTCTTGGTGTATTAGAAGAACATGTAAATAAGCATCTTGGGCTCAAACCTTATAAATGTGAAGAATGCGACAAATGTTTTGCTTCAAAAAACCATCTTAGTTTACATAAAAGATGCCATAATACTAGTGAGATTTATAAATGTGCAAAATGTGGTAAAGAATTTAGGACGAGTGCTTCTTTACGCAGTCATCGCTTTGTACATTATGAAAAAATAGTGGAAGATTTCAAATGCAAAGTGTGTGGTCATAGCTCTGTAGACGAAGCTAAGCACAAAGCTCATATGTCAATACATGCAAAAAAAGCAGAAATTAGATGTGAATTGTGTAAGAAAGCTTTCAATACTGAACGTGGTTTAGAAAGTCATCTAAGTACTCATAATGAATTGAAATTTCCTTGCGAATTTTGTGGTAAAATATATCCTTCAATGTATAGAATAAAAAGGCACATCAAAAGAGCCCATGCACCGTGTAAATGTGAACACTGTGATCAGATTTTTCATGATCGTTTTCTTTATAATAAGCATATAAAAGAACACAGCCAGCAAACCAAATATGAATGCGAATACTGCCAAAAAGTTTTCGAAAAAGCCAAAAACCTTTCTGAACACTTTCGTCTTCAACACAAACAAGACGGAGAAAAAAGAAAGTGTCCCATTTGTAGCAAAGAATTCATCAACAATGCACTGCTAAAGAACCACATCAAAACGCATGACAAATGCTTCAAATGTAAACTTTGTGATAAAGTTTTTTCTTCCAGATACAATCTAGAAATCCACATGAATACTCATTCCGGTGCGAAGAACTTCAAATGCGATATATGCGGTAATCATTTCGCTAGCAAAACTAGTCTTAAAAATCACATTGCTACTCATTCGGATGAAAGGAAATTTCAATGCGAAATTTGTGCTAAGACGTTTAAAACGTCCAGAAGACTTTATACGCACAGTCAAAGTCATGCTACTGAAGAGAAGTATCAGTGTGAGATATGTCTACAGAAATTTAGAGTCAAACAGTATCTCAAAGCTCACATGTACAGACATTCCAAAGTAAAACCGTTTTCTTGTGACATTTGCAAGAAGCGGTTCAAACACAAAAAAACGAAAGAAAAACACATGCGAATAGGAAAACATCAACACGTGTCCGAAGAACACGATTGCGATTTTTGCGACGAAAATTTCTCGACGAGAGATTTGTTGTTGGATCACTTCGCTGCAGTTCATCACAATGAAAATGTTGTTAACGAATGCGAGAAAGATATCGAAGAAGATGAAGATAACAAGGAGTTAGATAATGTTGCAAATGGCGATGAAGTAGCTAAAATGGAAGTAGATAAGAGTAAAAGTGATTTATTATTTGTATGTACAGTGTGTTCCTGA
Protein Sequence: MKSESNNEQDQVNIKKEPTIENESKPEDNSNVDLPILNVKLEPPECSASEKVIKMEIKPELPLDFEPNQSENIVDIHEENLNISFEELKALNDDLTIIDNETTVYKCQICEVVFIKYQEYRLHKKNHYIEKRRCYICHKVQQSLGVLEEHVNKHLGLKPYKCEECDKCFASKNHLSLHKRCHNTSEIYKCAKCGKEFRTSASLRSHRFVHYEKIVEDFKCKVCGHSSVDEAKHKAHMSIHAKKAEIRCELCKKAFNTERGLESHLSTHNELKFPCEFCGKIYPSMYRIKRHIKRAHAPCKCEHCDQIFHDRFLYNKHIKEHSQQTKYECEYCQKVFEKAKNLSEHFRLQHKQDGEKRKCPICSKEFINNALLKNHIKTHDKCFKCKLCDKVFSSRYNLEIHMNTHSGAKNFKCDICGNHFASKTSLKNHIATHSDERKFQCEICAKTFKTSRRLYTHSQSHATEEKYQCEICLQKFRVKQYLKAHMYRHSKVKPFSCDICKKRFKHKKTKEKHMRIGKHQHVSEEHDCDFCDENFSTRDLLLDHFAAVHHNENVVNECEKDIEEDEDNKELDNVANGDEVAKMEVDKSKSDLLFVCTVCS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00736022;
90% Identity: iTF_00736022;
80% Identity: -