Lcap001672.1
Basic Information
- Insect
- Lochmaea capreae
- Gene Symbol
- -
- Assembly
- GCA_949126875.1
- Location
- OX421395.1:25735790-25738613[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 1.5 1.5e+04 -2.7 0.0 47 58 81 92 79 116 0.79 2 3 3.2e-15 3.1e-11 44.4 0.6 8 70 237 297 232 301 0.85 3 3 2.3 2.3e+04 -3.3 0.0 32 48 407 423 400 429 0.71
Sequence Information
- Coding Sequence
- ATGGAGAGCATTAGAAAATCACGTAGTAGTTCCAGATCCGCAGTTTCGGAGCTGGACTCAACAGAAAGAACGACAAATTTTAATGgaagtaatttaaatttaacagaattaaataatgaaaacccCATAGAAACTGCTGAAATTAACACATGTAAAAGTATAAATCAAAAAGTAGAAAATGAAAACACCGAAATTGCGGAAATAATGAGCTGCTGTGAAAATAATGAATCTGAACCTGTTAAAGATGTAACAGCATATATAAAGGAAGAAGAAAATGCAGTAATTACAGATAATCCCAAAGAAAAAGTCTCAAGAGGAAGGAAACTGAAATCACTTGAGACATTGcaaactgataatatttcatgTGAAACTAAAAAAGAATTGATGGAAGTAACTTCACCAGTAGATCCTTTAATATTAGTAAAagAAGAACCAGTTGACATGGAACTGTATTCTGTAAGCACCTCCGAAGTTCTAGGCAAAGGGAAGAGAGCTCGAATACCAAACAAAAGGTACAGTGATATTGTTCTATCACCAACACATGCTAAGAAATCCCTTTCGCTGGTGCCAGAAAATGGGGACGATACAAATACTTGCATAAAAGAAGAATTTGGATTAAGCCCTTCTTATGGTTCATCAGCATCTAGAAATTCCAGTCCTCCATTAAAGAGAACAAAATTATCAACTGACTTATCAGATCCTAAATATTTGAAACCTTTTAAATATGGATGGCGAAGAGAGCTAGTTTGGAGAGGTACTTATGATGAAAGTAAAAGTAGAGTTGGTGATATTTACTACTACTCCCCACAGGGAAAAAAAGCTAGATCTAGAAGAGAGGTTGTTGAACATTTAAGAAACAAAGAACTTACAATAGATAACTTCTCTTTTTTTAAAGAGCCAATAGGTATTGATGATCctgaaaaagaaataataagagaTGCTAAAGTGAAACAATCAGAATTTCTTACAAAACCAGTTGCCgtaaaacttttgaaaaatactgTACAGTCACCAAAATTACCTAAATTATCTAGTAGTGAACCAACTAATTCAAAATTaaccaataaaaaattgaacaatACAAAAGTTGCAAAATCAAAGTTTGGAAGTGCTAAAATGAGAGGTTCTATTTTGACAGGTCCCAAATCTAGAGGTCCTAAAGTTTCACTTACAAGACTTAAGGGTCATGGGAGAATCAAAACAAAACTTAAGTTAAGTGATGTGTCTACTAAAGCTCCTTCTAAAAGACGTGCTAGGCAGAGAAACAATACGGTAAGTTTAATATTTCCAGTTCATTGCTTGAAATACTAA
- Protein Sequence
- MESIRKSRSSSRSAVSELDSTERTTNFNGSNLNLTELNNENPIETAEINTCKSINQKVENENTEIAEIMSCCENNESEPVKDVTAYIKEEENAVITDNPKEKVSRGRKLKSLETLQTDNISCETKKELMEVTSPVDPLILVKEEPVDMELYSVSTSEVLGKGKRARIPNKRYSDIVLSPTHAKKSLSLVPENGDDTNTCIKEEFGLSPSYGSSASRNSSPPLKRTKLSTDLSDPKYLKPFKYGWRRELVWRGTYDESKSRVGDIYYYSPQGKKARSRREVVEHLRNKELTIDNFSFFKEPIGIDDPEKEIIRDAKVKQSEFLTKPVAVKLLKNTVQSPKLPKLSSSEPTNSKLTNKKLNNTKVAKSKFGSAKMRGSILTGPKSRGPKVSLTRLKGHGRIKTKLKLSDVSTKAPSKRRARQRNNTVSLIFPVHCLKY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00911950;
- 90% Identity
- -
- 80% Identity
- -