Lqua022917.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lithosia quadra
Gene Symbol
egg
Assembly
GCA_963576445.1
Location
OY754903.1:3745400-3778551[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 3.7 1.3e+04 -3.7 0.0 28 38 1805 1815 1798 1816 0.77
2 2 2.8e-13 1e-09 38.3 0.0 4 73 1847 1909 1844 1913 0.86

Sequence Information

Coding Sequence
ATGAGTTCCACAGACGATGTAAGCAGCAGTAAAGATGAAGAAGACTTATTGAACAAAGATTCAATCCGTAGTGCACTGGAAACTAGAGATATATCTGATATAAATACATCGAGCAAAAACTCCTCAGCTACGACAGATAATCCAGAAAATAGAGCTAAGATGACTGACAGTGCTGCTACAGGACTCTCAGAAACCTCTAACAATGAATCTGGCGATAAAAAAACGATTACTCTTGAAGATACGGCTAAAATGATCGATGAAGTCACTTTGGGAGTCTCAGATAACAGTAATATTGAACCTGGTGATAATATTATGAGTACTGTTGAAGATACAGGTAAGATAACTAACTTAGCCACTACAGGACTCTCAGAAAACACTAATACGGAGTCTGGTGATATCATTACAAGTATTTTAGATACAAGCTCTATATCGGTATCTGAATCTATAGTCATACCTTTGGAGACAGGTGAAACCAGTGCTGAAAATGCAACTATAAGTGAGACTGCTGATAGTACACAGGATCTTCATGAAGCAGCTGTTGAGGAAGCTAGCGTAGAAGAAGGAAAAGTTGCTcttacaaatgtagaaaaagtTGAAATTGAGACTGAAAACGTTAGAGGTGATTTAGAGGAAGAAGAGGATATAGAGTTACGATGGGAAGATGAAGATGGAGCCGGTTTAATCACTGGTGATACAACTAATGATACTAAAAAGGATGATTTAGAAAATGTACCTCCTGATGATGTAGAACAAAATGTTGAAGCGATTACAGATAAACCGTCTACAATTGAAACTAAATCTATCTCAGAGGGTAACGCTCAAGTAACTGAAACAGCTGAATCTGAAGAAACAATTAACAAAGATACTGAACTGGTCGTAGAGGAAAATCTTTTAAAAGAAGCTGTTACTACATCGGAAAATCCCTCGTCACATGTTTCTATGGAGTATACTGAAGATGAATTACTCAAGGATGAACAGCCTGAAGACTCAGAAATGATGGAGGTGGACACTATTGATAAAAACTTGGTAGTTCCTGAAACTATTGAAGGAATCGTTGAAACATCCGATGATGATActaaaatacaagaaaaaattagtaaacatgatgaaattaaaataattgataaacCTAACAGTTGTATAGAAACTAATACGGTATTAGTTAAAGATAATATCGATAaaaataacactaaagaaaTAACGGAATCTACCGCAGTGCAAATAACCGCTGATGAACCTAATTCAAGTAACAACGATAGACAAGAACTTAGTCTATCAATGGACGTAGATTCTGGCAATACATCCGTAGAAAGTTCTGGAATTCAATTTAAAACCCATGGTCTTCATAAACCGGATGTTATGTTAGAAATACCAACACAACCGGCGATATATATACATGATGCGTTAGATAGTCCAAATTATGGCTTAAATGATGATGGTGTTACAATGGCTGAGAAAAATAATATGGAGGACTATGGTCTATCAGTCAATGAAGACGTAAGTATGGAAGTTGAGACAGCCGTAGTTGAAGGTGCCGTAGAAAGTATTCGTGACATGCCTGATGCACCTGCTGGAAAGAAAGTAGAGGATTCTCAGGTTAATGCAGAAGTTATTGCTACGGGAGcTTCCGTAATTGATGAAGTCCAACCATCCACATCAACAGTCTTTCCAAAGATGACTCCAGACACATCAGATGAAGTCCCAGAGATGACTGACAGTCTTGGTCTGCTGGCCGAGTCTTCTAGAGTGATGgacgatgatgatgaccaaGACGATGATGATGGAGAtgcagatgatgatgatgattctgaCCAGGATGATAGCAGCAATCACATGACTGCCGAACATTCAGAAGACTCCAACGCACCACATTCTGAGAATGAGCATGAACACATGAAAACTGATATTGATATGGAATCTGAAGATATGGGAGACAATATCGAAGAGACGGAGACCAACCAATGTGAAGAGGATTTTAATGGTGATGAGTGTGATATAGACGAAGAGGATGGTGATGGAATTAGCAATTATGACCATAACGGTGATGAAGATGATcagGAAATGCCAGCAATTATAGGCGTGAGTTCTGAAGCTATGATAAAGATAGAAAAAGGTACTGAAAAGATAAATGAAGAAGATAATATAGATGTTAATATAAAGCAGGAAGACAGTACGCAATCACCAGTTGATAAAATACACGAAGATGTAAGCCAATCGAAAGAAACAGTCCACAGTCTAGAAGATACTGTTCAGTCGATAGACGTAGTAAAGGAAGAAAAAGAAGACTCGGTTCAACCAAAAGATGCAgtacataaagaaaaagaagTCATAGTTCAACCGAAAGATGcagtaaataaagaaaaacaaggCACGGTTCAACCGAAAGATGcagtaaataaagaaaaacaaggCACAGTTCAACCGAAAGATGcagtaaataaagaaaaagaaggtTCGATTAAACCGAAAGACGTAATAAAGATAGAGAAAGAAGACTCCGTTCAACCGAAAGACACGAAAAAGGAAAAAGATTTTGATTTGAAACCAAAAGAAAGCGTTACTGCCAAAGAAGTGGCTGAAAAGGTAGCTAAAGATGCACGTCCGATATCACGCGCTGAATCTGAAAATTCTAATGATGATTGCATCGAACAACCTATCGAAATAGAGACTGTCAAGGTAtctgatgacgatgatgatgatgatattgagCTTCCGAAGGTACAGGACGATAAAATTATGCCCCAGCAGGTAATTCCATTAGAGAAAATAACGTTGAAAGACAGTACGACAGTTGAGAAGACGGCTGAATCAGAAAAGACTTTAGAATCAGAAAAGACGTTAGAATCAGAAAAGGCATTAGAATCAGAAAAGATGTTAGAATCAGAAAAGACGTCAGAATCAGAAAAGTCGTTAGAATCAGAAAAGGCGTTAGAATCAGAAAAGTTGGTAGAATCAGAAAAGACGTTAGAATCAGAGAAGGCAACAACATCAGAAAAAGAGTCAGAGTCGAGAGCAGGAGTAGAGAATGCAACTATAGATCTTTCACCATCGAACAAGGCTAACATTGAAGGGCCACAAACAGATGGACCAACTCCCAAGTCCTCTCCGAACAAGTTGAAGAACTTATCTGTGTCATCCATACTTAACACAAATGTACTCAGTTTTGTGGAACTGGGGGGATCCTCAGATGATTCAGATGTCCAAGAAGTTGAAAAAGAACCAGAGCATACACTATCACACCTCCAGAAACTTCTAGAAACGAAGTCCGTGCCGCCAAAAATCAAAGAGCCATCACTCAAAACCGTGGAGTCATCACCCAACCCTCCATCTAACGACGTCACATCTGTCAACATACCTACTGGAATTGATATCATGTCAACATCTGGTGTTGGCGGCAATAGGTCACAAATTGTTACTAAGGAAGGAGAAGTGGTCATAAGTGGTGTGGCGAAACCTCCCCCTCATAAACCTGCGAGATTGAATACTAGCGAAGTGACCATCAAGACTGCAAGCTGTTCAGAGCAGACGTTGGTCATACCAGAAgctaagACAAAAGAACAGGCTAAACCTGCAGCCACAAAACCTAAACTCAGCTTAGAAATATTCAGCCTAGACTCTGATGAGGAGGAGACTCCTgctaaagTAGTAGAAAAACCAACTTCCAAGACTGATGCCAAGTGCGTGGCGCCAAAGAAGAAACAAAGGAAGTGCATGAACAGCTCTTGCTCTAGCGGCTTGACAGTCCTGCAAGCCGCTGACAACGCCACAGTGGCTTACTACGACGCTTCGAGGAAAAAAAAGCCGGTTGTATGCCAGGCTTGCGCTCAAGCCGTACTCGACAGGAAACAGAATCTAGTGGATGGTATCAAGAACTTCACCCCACTGTTGGAACTGGACATGACAGTAGCTCAGGACCTGGTCGAGATTCTGGACTCGGAGTCGGAAGACGAGGAAACGGTGCCAAAGGATCAGCAACCCAGGGAAACCATTGGAGAGGAGACGGCCAAATTCTTAGAAGACAACCTGACGGACCTTCTGAACGACGCGTGGAAGAAATACAAACTGGATGACAGACTGAAAGAGACGCAAGATGAACTCAACGCTGAGATGTTGAAATTGGAGGAGGATAGCAAGGAGATAAACCAGATGTTGGTGGACTGCCAGCGCGCTACGGACAAGCTGCGCTCGGACCTGTACGCTACCTTCGAGTACCGCGTACAGGAGCTACAACCGCTGCTCATATTTAACACGCCTGaattctatTACATTGGACCGGAAGCAGAAAACGTTATACCAGCTAATGTAGTTACTGAATCCCGATTGAGTGCCAAGAGGAAAATGATATCCAATAATGAGCCTCAAGCCAAGAGACCAGCCATCCCACTGGGATACGCGCCGTTGGATGACTCCAAATTGAAAGTACAGAAAGATATCTCCGTTGTCAAGTTGTCAGCGGAGGCAGCACCGGCGGACCTGCCGCCCCCCGGGGAGCTGACCCGGCCCGGCCTGCGCGTGGGGCTGGCGGTCTACGCCATGAAGAACGCCTTCGGACCCTGGTTCAGAGGCAGGATACTGGAGATCATGCCGAAAAGCAGTATCCCTACAAATTTCATGATGTGCCGCATAAAATTCGACCATAAAGTGAAGAATAACGGCAAGGTTCTGCCCGCGAGGTGCATAGCATATGCAGAGCCGGCTGACGTGAGAATGACCATAGGCACACGCCTCATAGCGTTATTCAAAGACTCTAACAAACGCGAGTCTTACTACTCCGGAGTGGTCGCCGAGATACCCAACCCAGTCAACAACTATAGATACCTAGTATTCTTCGACGACGGGTACGCTCAGTATGTGAGCCATTCCTTCACGAGGCTGGTGTGCGAGAGTTCCCCGCTGGTGTGGGAGGAGGTCCACCCCCTCTCGCGGGAGTTCGTGCGCGAGTACCTCATGGCCTACCCCGAGAGGCCCATGGTTCGCCTGCATGAGGGACAGCATCTCAAGACTGAGTGGGACGGAAAATGGTGGTCGTCTCGTGTGAATAAAGTAGACGCATCTCTCGCACAAGTGGTGTTCATCGGCGATGGCCGCAGGGAGTGGATCTACAGGGGCTCCACCCGCCTGGCGCCGCTGTATCTGGAGCTGCGGGCTGCGGAAAGGCACAGGCCTAGGCCTATGCCCCGCAGCAAGCAGCCACGGTCCCATATGATGCCGTACGTGGAGTACACCCGTTCTGATGAACAAGCGAACAAGTCCCAAGAGTCACACCCCATTCCTGTGGCTTTGACTGCACAGCAACATAACGAGGAGATGCGTCGACAACGCGCGGTGGCCAAGAAGTCCACAAGCCTAGCGGCCGCGTCTTCTGTCCCGCCCGGGCCGCTCCCCGCACCCCCCCGGACCGGGAACCTGGATGCCGTCACCAGCAGGGTTGTGTACTACACGCCAAAGCACTCAATCCGCCCTCACAAGTTGGTGCCTCACACGTGCTCGCCCAAGTGCAAGCGGAGTGACCTGCTGTCCCTCAAGGAACTCCGGACTTACAACCCTCTGGCGAAACCGTTGCTTAGCGGCTGGGAGAGACAAATAGTGAAGTACAAGGGCCAGAAGGGAGTGATGTACCGCGCGCCGTGCGGCCGGCGCCTGCGCAGCCTGGCCGAGCTGCACCGCTACCTGCGCGCCACCGACAGCGAGCTGCCCGTGGACCTGTTCGACTTCTTCCACGGCACGCACTGCCTTGCCGAGTTCGTGCTCAACAAGTGCCTCGTGGGGAAGAAGGACTTATCTCATGGCAAGGAGAACGTGCCGGTGCCCTGCATCAATTACTACGACGACACTCTGCCGGAGTTCTGTTCGTACAACACCGAGCGGACCCCCACTTCCGGGGTCCCACTCAACTTGGACCCCGAGTTCCTGTGCGGCTGCGACTGCACCGATGACTGTGAGGACAAGAGCAAATGCGCATGTTGGAAGATGACGCTAGAGGGCGCGCGCACCATCGGCCTCGACGTCAATAGCGTCGGCTACGAGTACAAGCGCCTGCCTGAACCGCTGCCCTCGGGCATTTACGAGTGCAACTCTAGaTGTAAATGCAAGCAGACCTGCCTTAACCGCGTCGCACAGCATCCGTTACAATTGAAACTACAgGTGTTTAAAACGCTGAATCGCGGTTGGGGTATCCGCGCGCTAAACGACGTACCAAAGGGCGCGTTCTTATGCGTATACGCAGGGAACTTGCTGACCGACGCCACCGCTAACCTGGATGGTTTAAATGAGGGGGATGAATACCTCGCGGAGCTGGACTATATCGAGGTGGTGGAACAGATGAAGGAGGGGTACGAGGAGGAAGTAGCTGAGCCTGACAAGAAACAAGACAAGGAAGGTGCGAAGCAAGAAGACTCCGAAGAAGAACCTTCTTCATCGtcggaagaagaagaagacgcGTCGAAGACTGACGAGAAAGATGACGACTTCAGGCCAGGGTTCATTTCTCTCGGACTGGCGGACTTCAATAAACGCCTCCGCAAGCGGTCCAAGAACAAAAAAGAACAGAGCGAAGGCAAAGAAGAGAAAGACAAAGAGAGCAAGCCTACAGAACGGAACCCTGACGAAGACTGCATCACCAtcagtgatgatgatgaagttCGTGAGCCGTCCAGGTTTACTGCGAAGCCTGGAATGGGCGGGAATGACTTCATATCTAAGTACAGGTCCGTCCGTACGTTGTTCGGCGAGGATGAGGCGTGTTACATCATGGACGCCAAGGTTCAAGGCAACATTGGACGATATCTCAATCATTCGTGTTCCCCCAACGTGTTTGTCCAAAACGTGTTCGTGGACACCCACGACCCACGCTTCCCCTGGGTGGCGTTCTTCGCGCTGTCCCACATCAAGGCCGGGGTGGAACTCACCTGGAACTATAATTATGACATCGGTTCCGTGCCGGGGAAAACTTTGTATTGTTACTGCGAAGCGCCTAATTGTAGGGGGCGACTATTGTAA
Protein Sequence
MSSTDDVSSSKDEEDLLNKDSIRSALETRDISDINTSSKNSSATTDNPENRAKMTDSAATGLSETSNNESGDKKTITLEDTAKMIDEVTLGVSDNSNIEPGDNIMSTVEDTGKITNLATTGLSENTNTESGDIITSILDTSSISVSESIVIPLETGETSAENATISETADSTQDLHEAAVEEASVEEGKVALTNVEKVEIETENVRGDLEEEEDIELRWEDEDGAGLITGDTTNDTKKDDLENVPPDDVEQNVEAITDKPSTIETKSISEGNAQVTETAESEETINKDTELVVEENLLKEAVTTSENPSSHVSMEYTEDELLKDEQPEDSEMMEVDTIDKNLVVPETIEGIVETSDDDTKIQEKISKHDEIKIIDKPNSCIETNTVLVKDNIDKNNTKEITESTAVQITADEPNSSNNDRQELSLSMDVDSGNTSVESSGIQFKTHGLHKPDVMLEIPTQPAIYIHDALDSPNYGLNDDGVTMAEKNNMEDYGLSVNEDVSMEVETAVVEGAVESIRDMPDAPAGKKVEDSQVNAEVIATGASVIDEVQPSTSTVFPKMTPDTSDEVPEMTDSLGLLAESSRVMDDDDDQDDDDGDADDDDDSDQDDSSNHMTAEHSEDSNAPHSENEHEHMKTDIDMESEDMGDNIEETETNQCEEDFNGDECDIDEEDGDGISNYDHNGDEDDQEMPAIIGVSSEAMIKIEKGTEKINEEDNIDVNIKQEDSTQSPVDKIHEDVSQSKETVHSLEDTVQSIDVVKEEKEDSVQPKDAVHKEKEVIVQPKDAVNKEKQGTVQPKDAVNKEKQGTVQPKDAVNKEKEGSIKPKDVIKIEKEDSVQPKDTKKEKDFDLKPKESVTAKEVAEKVAKDARPISRAESENSNDDCIEQPIEIETVKVSDDDDDDDIELPKVQDDKIMPQQVIPLEKITLKDSTTVEKTAESEKTLESEKTLESEKALESEKMLESEKTSESEKSLESEKALESEKLVESEKTLESEKATTSEKESESRAGVENATIDLSPSNKANIEGPQTDGPTPKSSPNKLKNLSVSSILNTNVLSFVELGGSSDDSDVQEVEKEPEHTLSHLQKLLETKSVPPKIKEPSLKTVESSPNPPSNDVTSVNIPTGIDIMSTSGVGGNRSQIVTKEGEVVISGVAKPPPHKPARLNTSEVTIKTASCSEQTLVIPEAKTKEQAKPAATKPKLSLEIFSLDSDEEETPAKVVEKPTSKTDAKCVAPKKKQRKCMNSSCSSGLTVLQAADNATVAYYDASRKKKPVVCQACAQAVLDRKQNLVDGIKNFTPLLELDMTVAQDLVEILDSESEDEETVPKDQQPRETIGEETAKFLEDNLTDLLNDAWKKYKLDDRLKETQDELNAEMLKLEEDSKEINQMLVDCQRATDKLRSDLYATFEYRVQELQPLLIFNTPEFYYIGPEAENVIPANVVTESRLSAKRKMISNNEPQAKRPAIPLGYAPLDDSKLKVQKDISVVKLSAEAAPADLPPPGELTRPGLRVGLAVYAMKNAFGPWFRGRILEIMPKSSIPTNFMMCRIKFDHKVKNNGKVLPARCIAYAEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVSHSFTRLVCESSPLVWEEVHPLSREFVREYLMAYPERPMVRLHEGQHLKTEWDGKWWSSRVNKVDASLAQVVFIGDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKQPRSHMMPYVEYTRSDEQANKSQESHPIPVALTAQQHNEEMRRQRAVAKKSTSLAAASSVPPGPLPAPPRTGNLDAVTSRVVYYTPKHSIRPHKLVPHTCSPKCKRSDLLSLKELRTYNPLAKPLLSGWERQIVKYKGQKGVMYRAPCGRRLRSLAELHRYLRATDSELPVDLFDFFHGTHCLAEFVLNKCLVGKKDLSHGKENVPVPCINYYDDTLPEFCSYNTERTPTSGVPLNLDPEFLCGCDCTDDCEDKSKCACWKMTLEGARTIGLDVNSVGYEYKRLPEPLPSGIYECNSRCKCKQTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEEVAEPDKKQDKEGAKQEDSEEEPSSSSEEEEDASKTDEKDDDFRPGFISLGLADFNKRLRKRSKNKKEQSEGKEEKDKESKPTERNPDEDCITISDDDEVREPSRFTAKPGMGGNDFISKYRSVRTLFGEDEACYIMDAKVQGNIGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGVELTWNYNYDIGSVPGKTLYCYCEAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-