Basic Information

Transcription Factor Domain

TF Family: CBF
Domain: CBF_beta domain
PFAM: PF02312
TF Group: Beta-Scaffold Factors
Description: Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00063 8.1 6.6 0.2 17 43 60 87 54 95 0.84

2 5 0.00064 8.1 6.6 0.2 17 43 96 123 90 131 0.84

3 5 0.00066 8.4 6.5 0.2 17 43 132 159 126 166 0.84

4 5 0.0004 5.1 7.2 0.2 17 43 168 195 162 201 0.84

5 5 2.4e-05 0.3 11.2 0.4 17 74 204 261 197 283 0.78

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00063	8.1	6.6	0.2	17	43	60	87	54	95	0.84
2	5	0.00064	8.1	6.6	0.2	17	43	96	123	90	131	0.84
3	5	0.00066	8.4	6.5	0.2	17	43	132	159	126	166	0.84
4	5	0.0004	5.1	7.2	0.2	17	43	168	195	162	201	0.84
5	5	2.4e-05	0.3	11.2	0.4	17	74	204	261	197	283	0.78

Coding Sequence: atgTTGTTTGGTGTCAATGAAAGAGACCACAACGCCATACCTCCTATTTTTCTTGATGGCGCACCTCTCAATAGGGTtagacaatttaaatatttaggacATATCTTAACTGACGACTTGAAAGACAATGCAGATATTGAACGTGAACGTAGGGCGCTGTCTGTCCGCGGTAACATGTTGGCACGCAGGTTTGCTCGTTGTTCGACTGAGGTCAAACTTACAGTATTTAAAGACAATGCAGATATTGAACGTGAACGTAGGGCGCTGTCTGTCCGTGGTAACATGTTGGCACGCAGGTTTGCTCGTTGTTCGACTGAGGTCAAACTTACAGTATTTAAAGACAATGCAGATATTGAACGTGAACGTAGGGCGCTGTCTGTCCGTGGTAACATGTTGGCACGCAGGTTTGCTCGTTGTTCGACTGAGGTCAAACTTACAGTATTTAAAGACAATGCAGATATTGAACGTGAACGTAGGGCGCTGTCTGTCCGCGGTAACATGTTGGCACGCAGGTTTGCTCGTTGTTCGACTGAGGTCaaacttacattatttaaagaCAATGCAGATATTGAACGTGAACGTAGGGCGCTGTCTGTCCGCGGTAACATGTTGGCACGCAGGTTTGCTCGTTGTTCGACTGAGGTCaaacttacattatttaaagaCAATGCAGATATTGAACGTGAACGTAGGGCGCTGTCTGTCCGCGGTAACATGTTGGCACGCAGGTTTGCTCGTTGTTCGACTGAGGTCaaacttacattatttaaagcATACTGCCAATCTTTTCACACGAGCAGCCTATGGGTTAATTATACGCAGAGGGCATACAGTGCCCTACgagttcaatataataatgtgttcAGGGTGCTGTTGCGGTTGCCGCGCTTCTGTAGCGCATCGACGATGTTTGCCGAAGCACGTACTGATGATTTCTATGCCATCAGACGCAAACGTATAtcgtcattgatatgcagactGCGTGGCAGCAGTAACATCATTCTGAGCAcattaatagataaatatgaCTGCCCTATCCAGGCATACTGGGTAAAATTTGCTATTGGGGCTATTAAGTGa
Protein Sequence: MLFGVNERDHNAIPPIFLDGAPLNRVRQFKYLGHILTDDLKDNADIERERRALSVRGNMLARRFARCSTEVKLTVFKDNADIERERRALSVRGNMLARRFARCSTEVKLTVFKDNADIERERRALSVRGNMLARRFARCSTEVKLTVFKDNADIERERRALSVRGNMLARRFARCSTEVKLTLFKDNADIERERRALSVRGNMLARRFARCSTEVKLTLFKDNADIERERRALSVRGNMLARRFARCSTEVKLTLFKAYCQSFHTSSLWVNYTQRAYSALRVQYNNVFRVLLRLPRFCSASTMFAEARTDDFYAIRRKRISSLICRLRGSSNIILSTLIDKYDCPIQAYWVKFAIGAIK

Sequence clustering based on sequence similarity using MMseqs2