Basic Information

Insect: Lithophane ornitopus
Gene Symbol: Zfa
Assembly: GCA_948473465.1
Location: OX419638.1:10963273-10975270[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0046 0.32 11.8 1.4 1 23 258 280 258 280 0.98

2 10 0.036 2.5 9.0 0.3 1 23 287 309 287 309 0.98

3 10 4.5e-05 0.0032 18.1 3.7 2 23 342 364 341 364 0.94

4 10 9.9e-05 0.0069 17.1 0.5 2 23 371 393 370 393 0.96

5 10 2.8e-05 0.002 18.8 0.2 1 23 406 428 406 428 0.96

6 10 1e-05 0.00073 20.1 0.3 1 22 434 455 434 459 0.94

7 10 0.00023 0.016 15.9 1.1 2 23 468 490 467 490 0.95

8 10 2.1e-05 0.0015 19.2 0.7 1 23 496 519 496 519 0.97

9 10 1.7e-05 0.0012 19.5 0.2 1 23 528 550 528 550 0.98

10 10 0.0022 0.16 12.8 0.4 1 19 556 574 556 579 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0046	0.32	11.8	1.4	1	23	258	280	258	280	0.98
2	10	0.036	2.5	9.0	0.3	1	23	287	309	287	309	0.98
3	10	4.5e-05	0.0032	18.1	3.7	2	23	342	364	341	364	0.94
4	10	9.9e-05	0.0069	17.1	0.5	2	23	371	393	370	393	0.96
5	10	2.8e-05	0.002	18.8	0.2	1	23	406	428	406	428	0.96
6	10	1e-05	0.00073	20.1	0.3	1	22	434	455	434	459	0.94
7	10	0.00023	0.016	15.9	1.1	2	23	468	490	467	490	0.95
8	10	2.1e-05	0.0015	19.2	0.7	1	23	496	519	496	519	0.97
9	10	1.7e-05	0.0012	19.5	0.2	1	23	528	550	528	550	0.98
10	10	0.0022	0.16	12.8	0.4	1	19	556	574	556	579	0.90

Sequence Information

Coding Sequence: ATGGATGAAAGTACTACTCGAAACCACAGTTACGAGGATGAAAAACCCGAATCGGCAAAGAAGTATTGCTTTGGGTGTTTGTGTTTAAATGAAGATAAAAATGTACAAAAATATGCATTTCAATGCGGCCCTCTCAAGAATATATTACAGATGGACCGCATATTCCTATGTTACCTGTGCAAGAGGATGGCTCGGCACACTGAACAATTCATACAAAATGTGCAAAGTAATCAAATACTATTGGAAAACTTTCAGAATGTAATGGATGAGACGCTAAAGTCAGTGTGCTCACAGATCCAACCGCTAGTCAATTTAACACAAGTGCCATTTGATGTGATAGAGTTGTCTGAGAGAGATGGCCATAGTTCTGAGGAGACCTTCTCTGTCGTATGCTCTAGGAGCAGGAGTAAGGATGTCCAGATCAAGATTGAGATGAAAGAGGAGGAGTATATGGATCATCTTGACGGAGAGTTTATTAATGGTGGTGATGAGTTCCCAGAGTCATACGTAAAAGATGAAGAAGATACATTCCCTTTAAAAGCATTACTGAAAGAAGAATTGCAACTAGAGGACATTGATGGCCTGGATCTCATGAGTCTTAGTGCGACGCTTAAGAAGAACAAACATAAGAAGAAAAGTAAAATCAAGCAGGAGAGCTTGACACAGATAAAGAGAGACATTCCTAAAATAAAGACGATATACATCACTAGGGAACAATGTATGGAAGAACGTGCGCGTATGGAGCAGGATCAGAAATATGTGGACTTTGCCTACAAATGTGGGAACTGCATCAAAGGGTTCAGCTTTAAAGGCAGCTATGATAAGCATATGGAGAAACATAATCAGTGTATGGGGGACTATGAGTGTGATATTTGTAAACAAAGAATGGATACAGAAGACAGACTGGTTGGCCATATGAGGTATCATTTAATTCGCTACAAATGTGCAGAATGTGGTTTAATAAGAAACTGTCGCATGACGATACAAGATCACTACAATGCTTATCACAGTCAGGGTTTTCAAACGTGTCCATTTTGCAGCAAAAATTTCAAACGTCAGACGTCACTACGCAAGCACATACACTACGCACACACGCACAAGGGCCGCGTACAGTGCGCATACTGCCACAAAACATACGCCGACAAAGGCGTACTGCGCTCTCACATGATCATTAAACATTCCAAAGAAGTATCAGCGGTTCCGATAAGCAAGAAGTTTGTGTGCCAAGAGTGTGGCATGGCCTTCAAGGCACCTTCTCAGCTGAGGAACCACAGCATCAAGCATTCCGACAGCCGGGACTACTACTGTGTGGAGTGTGATAAGAGTTTCAAATCAGATGCCGCATTGAAAAAGCATTTGAAGACTGCAGCCATGCACGTCAGTTATTTAGAATTAccATTGCCCTGCCTTCACTGTGACAAGCGTTTCGCGATACGTCGGGATCTAGAGAGACATACCAACAGAGTTCACCTAAATATCAAACCGTTTACTTGTGATAGATGTGATAAGAATTACGTGAACAACTGGTCTTTGAAGGAACATCAGCGGTTGGTGCACGAAGGGTACAAAAGACCGCTACAGTTCCCATGCCCTATGTGTGACAAGGTTTTTGATCGCAACCAGATACTGAAAGGCCACATCCGCACCCACACCGGGGAGCGTCCATACCAGTGCAGCAAATGTCCAGCTTCATTCAGCCAATCCAGCATACTTCGCACCCACGACAGACTTATACACCTCAAACTGACCAGGGATGGACGGCCTAAGGTCAAATAG
Protein Sequence: MDESTTRNHSYEDEKPESAKKYCFGCLCLNEDKNVQKYAFQCGPLKNILQMDRIFLCYLCKRMARHTEQFIQNVQSNQILLENFQNVMDETLKSVCSQIQPLVNLTQVPFDVIELSERDGHSSEETFSVVCSRSRSKDVQIKIEMKEEEYMDHLDGEFINGGDEFPESYVKDEEDTFPLKALLKEELQLEDIDGLDLMSLSATLKKNKHKKKSKIKQESLTQIKRDIPKIKTIYITREQCMEERARMEQDQKYVDFAYKCGNCIKGFSFKGSYDKHMEKHNQCMGDYECDICKQRMDTEDRLVGHMRYHLIRYKCAECGLIRNCRMTIQDHYNAYHSQGFQTCPFCSKNFKRQTSLRKHIHYAHTHKGRVQCAYCHKTYADKGVLRSHMIIKHSKEVSAVPISKKFVCQECGMAFKAPSQLRNHSIKHSDSRDYYCVECDKSFKSDAALKKHLKTAAMHVSYLELPLPCLHCDKRFAIRRDLERHTNRVHLNIKPFTCDRCDKNYVNNWSLKEHQRLVHEGYKRPLQFPCPMCDKVFDRNQILKGHIRTHTGERPYQCSKCPASFSQSSILRTHDRLIHLKLTRDGRPKVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01093377;
90% Identity: iTF_00906413;
80% Identity: -