Lorn017022.2
Basic Information
- Insect
- Lithophane ornitopus
- Gene Symbol
- gprs
- Assembly
- GCA_948473465.1
- Location
- OX419625.1:10989815-10999439[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.2e-09 3.2e-07 30.8 0.0 9 45 51 88 43 106 0.84 2 2 6.9e-06 0.0019 18.7 0.0 43 80 134 171 122 178 0.71
Sequence Information
- Coding Sequence
- ATGGATATCACTATCACCAGACATTTCAGTTTGGATGAATCGTCAATGCGAAGCGGGGCGCTAGCGGCAATGGAGGCAGAGCCTGACCTCAGCACCTTCGAGAACAAGTCAGGCTTGGCTGAGGACATGAAGTTCCTCGCCTCTATGCCCGAGCTGTGTGACGTCACGTTTCTGGTGGGAGATACCAGGGAGCCGGTGTGCGCTGTCAAGGCCGTGCTGGCAGCGAGGAGCAGAGTATTTCAAAAGATGCTCTACCAAGCTCCCAGTCCTCAACGAAAGAAGGAACCAGCACCCAGGGAGAACAAACTACGATTATTCTTGAAAAGATCTTCGGAACCCCTGCTCAACCTTCAGAACGCCGCACAGCAGAGATCGACATTCGCGCAGCAATTGGCACCAATACAAGAGCCTTCTTCACAGCAGCATCAGACATTGATAATTGAAGAGTTCGAACCTGATGTCTTTCGCCAACTGATTGAATACATTCACACTGGATGCGTGACTCTGCAACCCAGGACATTGCTCGGTAAGTTGTCCTAA
- Protein Sequence
- MDITITRHFSLDESSMRSGALAAMEAEPDLSTFENKSGLAEDMKFLASMPELCDVTFLVGDTREPVCAVKAVLAARSRVFQKMLYQAPSPQRKKEPAPRENKLRLFLKRSSEPLLNLQNAAQQRSTFAQQLAPIQEPSSQQHQTLIIEEFEPDVFRQLIEYIHTGCVTLQPRTLLGKLS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01440252;
- 90% Identity
- iTF_00637858; iTF_01360866; iTF_00688003; iTF_00357797; iTF_00256103; iTF_01094217; iTF_00406058; iTF_01217653; iTF_00745962; iTF_00942988; iTF_00773037; iTF_00273781; iTF_00674453; iTF_00994511; iTF_00913786; iTF_00021499; iTF_00074715; iTF_00726622; iTF_01146526; iTF_00420684;
- 80% Identity
- iTF_00177347;