Lorn019661.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lithophane ornitopus
Gene Symbol
fru
Assembly
GCA_948473465.1
Location
OX419623.1:9727299-9738692[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.7e-27 7.2e-25 87.6 0.1 3 101 22 116 20 121 0.92

Sequence Information

Coding Sequence
ATGGACCAGCAATTCTGCTTGCGCTGGAACAACCACCCGAACAACCTGACTGATGTGCTAGCGAGCCTGCTACAAAGAGAGGCTTTGTGCGATGTCACCCTTGCATGTGATGGGGAACAAGTCAAGGCTCACCAGACGATACTCTCCGCATGTTCCCCATATTTTGAAAGTATATTCCTACAGAACCATCATCCACATCCGATAATATTCCTCAAAGATGTACGATTCTCAGAAATGAAATCACTTTTGGATTTCATGTACAAGGGTGAAGTGAATGTTGGCCAAAATATGCTACCGATGTTCCTAAAAACTGCTGAAAGTTTACAAGTTAGAGGTTTGACAGAAAATAATACATTGAATCCTAAGTCGGAGGATCGGTCAACTCCGTCAGTGAGTGCGGAGAACCTTTCCCGTTCGGAGTCGTTCGCCACGCCTCCGGCCGCACACTGCGCGCCGCCCGCGCCTCACACGCCGCTATCGGCCGCGCCGCCCGCGCACCCCTCACATCCCTCGCATGCAATCCCGCCGGAGAAGAGACGCAGAAAGAACTCAACAGTACCCCGAGACGATGTCGACCTTTCGTACAGGCACTATGAGGGTCACGTGAAGTCGGCGAAGTGCGGGTCGACGGGGTCGGGCTCGGAGCCGTCCACGCCGCCGCCGGCGCACACGCCGCACCGCGCGGTGGCGCGCTCGCCCGCGCACACGCCGGCGCCGCACGTGAAGCAGGAGCCCGACTCGCCCTACCCGCACGCGCCGCACGTGCCGCACGCGCAGCACGTGCCCAACCTCCACCCGCCGCCGCCCTTCGACCAGACGCACCTCCAGGGTATGGGAGTAACGGAAATGGCATCAATACTGACCCAGCAGAGCCTTAGTAATGAGTGCAACGACAACGAACCGATGTTGCAACCTCACCCAGACCAGACAGACACCATAGATGGTGAAAATAATGGCGTTGATGAAAATAAAAAACCATGGGAACCGTTTACAAATAAACTAGCGAGTGTTGAAAACATTGTCAAGTCTTTTGGTTTGGCACTAAGCAACAAACCACTCAGTGCTCCCGAGTCTTGTAACATTTGCGGAAAACTAGTTAATAATTTAAAAAAGCATATGAAGTCGCACAATCCTGAGCAGCACAAGTGCCCCATGTGCCCTATCACGCTCACTCGAGCCGATAACCTAAAGAGACACCTTCGCATGAAGCATTGTTCTGTTTTAAGCTCTGATAACTTGTCTAATATACAGAAGAAATGCCAACTTAGTTAA
Protein Sequence
MDQQFCLRWNNHPNNLTDVLASLLQREALCDVTLACDGEQVKAHQTILSACSPYFESIFLQNHHPHPIIFLKDVRFSEMKSLLDFMYKGEVNVGQNMLPMFLKTAESLQVRGLTENNTLNPKSEDRSTPSVSAENLSRSESFATPPAAHCAPPAPHTPLSAAPPAHPSHPSHAIPPEKRRRKNSTVPRDDVDLSYRHYEGHVKSAKCGSTGSGSEPSTPPPAHTPHRAVARSPAHTPAPHVKQEPDSPYPHAPHVPHAQHVPNLHPPPPFDQTHLQGMGVTEMASILTQQSLSNECNDNEPMLQPHPDQTDTIDGENNGVDENKKPWEPFTNKLASVENIVKSFGLALSNKPLSAPESCNICGKLVNNLKKHMKSHNPEQHKCPMCPITLTRADNLKRHLRMKHCSVLSSDNLSNIQKKCQLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00282560;
90% Identity
iTF_00907521; iTF_00726593; iTF_00850913; iTF_01028449; iTF_00364547; iTF_01117485; iTF_00364175; iTF_01119509; iTF_00111798; iTF_00301334; iTF_00446359; iTF_01085531; iTF_00302272; iTF_01118464; iTF_01363586; iTF_01363245; iTF_01362517; iTF_00449765; iTF_01526658; iTF_01340355; iTF_01526231; iTF_00449306; iTF_00186407; iTF_00037416; iTF_00036963; iTF_00785328; iTF_01192849; iTF_00039412; iTF_00038978; iTF_00888404; iTF_00038327; iTF_00037953; iTF_00274552; iTF_01084408; iTF_00148122; iTF_00147657; iTF_01285690; iTF_01361784; iTF_00622972; iTF_00623654; iTF_00300381; iTF_01538909; iTF_00447390; iTF_01026462; iTF_01029401; iTF_01031259; iTF_00445344; iTF_00237893; iTF_00017474; iTF_00177314; iTF_00906306; iTF_00951970; iTF_01030375; iTF_01094183; iTF_01095084; iTF_01093262; iTF_01094550; iTF_00374345; iTF_00745929; iTF_00831370; iTF_00071627; iTF_00071939; iTF_01441229; iTF_01230767; iTF_01247247; iTF_01247683; iTF_00425584; iTF_00001297; iTF_00001647; iTF_00924913; iTF_00758802; iTF_00758402; iTF_00851954; iTF_01532242; iTF_01534437; iTF_01534082; iTF_00185447; iTF_01533204; iTF_00928838; iTF_01065197; iTF_01063886; iTF_01062960; iTF_01064273; iTF_00685976; iTF_01062392; iTF_00685594; iTF_01062012; iTF_00712062; iTF_00929214; iTF_01064798; iTF_00120659; iTF_00121040; iTF_00273748; iTF_00072213; iTF_00122549; iTF_01527468; iTF_01527915; iTF_00908053; iTF_01027477; iTF_00121590; iTF_01425238; iTF_00040023; iTF_00042792; iTF_00041932; iTF_00043702; iTF_00043128; iTF_00123512; iTF_00772152; iTF_00809304; iTF_00810245; iTF_00173209; iTF_00375449; iTF_01440218; iTF_00327195; iTF_01221730; iTF_00450299; iTF_00383836; iTF_00973916; iTF_00974277; iTF_00018655; iTF_00018298; iTF_00050080; iTF_01342344; iTF_00124416;
80% Identity
iTF_00907521;