Basic Information

Insect: Lithophane leautieri
Gene Symbol: RREB1
Assembly: GCA_949152455.1
Location: OX424480.1:8038843-8043430[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.078 6 8.2 0.5 1 23 81 104 81 104 0.94

2 11 0.023 1.8 9.9 0.1 1 23 295 317 295 317 0.97

3 11 0.0013 0.097 13.9 0.4 1 23 326 348 326 348 0.99

4 11 0.00078 0.06 14.5 2.0 1 23 354 377 354 377 0.97

5 11 0.0031 0.24 12.6 1.6 1 23 731 754 731 754 0.96

6 11 0.00026 0.02 16.0 1.3 2 23 949 970 948 970 0.97

7 11 0.12 9.1 7.7 6.5 1 23 976 999 976 999 0.97

8 11 0.086 6.7 8.1 1.3 1 23 1032 1056 1032 1056 0.91

9 11 0.066 5.2 8.4 0.2 1 23 1080 1103 1080 1103 0.97

10 11 0.024 1.9 9.8 0.3 2 23 1143 1164 1142 1164 0.92

11 11 0.03 2.3 9.5 5.3 1 23 1170 1192 1170 1192 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.078	6	8.2	0.5	1	23	81	104	81	104	0.94
2	11	0.023	1.8	9.9	0.1	1	23	295	317	295	317	0.97
3	11	0.0013	0.097	13.9	0.4	1	23	326	348	326	348	0.99
4	11	0.00078	0.06	14.5	2.0	1	23	354	377	354	377	0.97
5	11	0.0031	0.24	12.6	1.6	1	23	731	754	731	754	0.96
6	11	0.00026	0.02	16.0	1.3	2	23	949	970	948	970	0.97
7	11	0.12	9.1	7.7	6.5	1	23	976	999	976	999	0.97
8	11	0.086	6.7	8.1	1.3	1	23	1032	1056	1032	1056	0.91
9	11	0.066	5.2	8.4	0.2	1	23	1080	1103	1080	1103	0.97
10	11	0.024	1.9	9.8	0.3	2	23	1143	1164	1142	1164	0.92
11	11	0.03	2.3	9.5	5.3	1	23	1170	1192	1170	1192	0.97

Sequence Information

Coding Sequence: ATGTACTCTTTTGTTACAGAAATCAAAACAGAGGAGGTCATCAGTGAAGCTAAAATCGAGGCCGACGCAGAAATGGACGGCGTTCAAATTGAAAAGCAAGAGCTCCGCGTCACTAGGACGACGAGCATCGACAGTGACAACCGATCTGACAGGAGCGAGGAGGAAGATTTGAGGAGAGCGCGCAAACGTGCCGCGTCCCAGTCACCATCACCCATCCCGATGGACAAAAGAACAGCAAAATTCGAGTGCCCCAAGTGCCGGCAGCGATTCGACTCGGTCAACGCTTTCGACATCCATCGATTCACTGCGCACAGTGACGACACCAAGACTGGCTTCGACGATCTTACCTTCGTCGATTTCTCAAGCAAGAAGTTCCCTGAAATTGCCAGAGGAGTCTGCGAGAAAAACCCTCATGTGTCAGTGACAGATCAACGTTATAGATGTGACATGTGCTTTAGAGACTTCCCTTGTGGGCAAGCTTTGGACATTCATAGGAAATCGTGCCTTTCTACCACCCGCATTCCTGTCAGTCCTGAAAGAGATCGCAGGGAGGATTTCTTTGCCAAATTAGATCTCAGAAACAGGTCTTTTGGCATTCCCGGTACGTTGACTCCACCAATGGACAGATTCACACCAAAATTCGATGATAATCATCTCACCAACGGCATAAGGCACATCGATGCCGCTCGCGATTTGGCAGATATTCAATCGATATTAAACGTCACGTCAGCTGGCGGCCTTTTAGAGAGGCTCACTGGCACCAGAGTGTCTTTAGAAAGTTCGGTTCTAACCCCTCCTGACACGATTATCAAGGATAGAGATCAAGAGGAAACCCAGGACAATTTTGCAGCAGAGTTCAGACGAATGAAGCTACGTGGAGAGTTCCCCTGTAGGTTGTGCCCTGCCAAGTTCCCTAACCTAAGAGCTTTGAAGGGACACAATAGAGTGCACTTGAGCGGAACAGGCCCGGGACCTTATCAGTGTAACATGTGCCCTCATGCGTCTTTAGATAAGGCTGCGTTAGTTCGTCACATGCGTACACATAACGGGGACAGGCCGTATGAATGTGCCGTCTGTAATTACGCTTTTACTACTAAAGCCAACTGTGAGCGACACTTGAGGAATAGACATGCTAAAGTCACACGAGAAGATGTGAAACGCTCAATAATTTACCATCCGTCTGAAGATCCTAATAATGATGAAGTGAACTCAAAACTTGCAAGGGATGAAGTAAAAAGATCACTCGCTTTCCACACCCCTGACATTGATAGGCGAAATGAAAGTTCGGGACGTGATACGCCGCTAACGCACTTTACTCCAAGTTTCATTACTGACAGACATCCAGTCACTAACTTAACAACCAAACCGTTATCATTGCCATTACCTGAGTCGCCTCTACCTCTGCCCATGCCAAGAGACGTAGAGCAAACTCAACCTCGAATTAAAGTGAAGGGTATTGGTCAGCTGACGCAAATACCTGAGTTCAGGCCACCAGAAATCACATACAAGCAAAATGACATCTCACACGATTCGTACGATGAAGAAGCTCCCGTAGATTTGAGCACAAGTGACAATAATAGTTGCGACGTTCTTGATCTCAGTAAGAAGAAACGTGACACCGATTCTGAGGAGCCTAAAGCACCACCACGTCCTTCCTTCGAGCCTGACCCAGCGAGTGTCGCTGCTTCAGCATACGAAAAGACAAGATTCCTCTTAGCTTCGCAAAGACTTTTTGAAAATTCTCTTCCTAAAATCGATCCATCTTACTATGCCACCCAGCTTTCACAGCTGTACGCCGGCACAGTTCCCGGAATCCCTGGTTTACCTTTGCCACCATCCTTTCCTATAGCCCCTTACTTACTTCAACCTTCGTTTTTTCCTCACCCAACTGATTCTCAGGAACTTGCCGAAATAAAACAGCATATACAGAAAGAAATCATTCGAGGCTTGAGCATGTCTGGTGGTAGACTCGTTCCTAATGACCAGGACAGTCAGCCTAAGATTGAGCCTGAAGAAGAGGAATTGAAACCACCGCCATCGATCTCTCCGATACCTTCGCCACACCCTGAATCTCCACGCCCACCTATGAATAACACTCTCGTCCCGCAAACGGACTCCGTGAAGATGGTAATAAAAAACGGTGTTTTGATGCCCAAGCAGAAACAACGGAGGTACAGAACTGAAAGACCTTTTTCCTGCTCTCAGTGTTCAGCAAGATTTACTCTCCGATCTAACATGGAACGTCATGTAAAGCAACAGCATCCTCAGCACTGGAGTGTAAGAAGACCAGCTCCGAGGGCGCCTCCACCGTACCCAACCCCCGATTCTTTGACTGATCGCATGAAATTTGCCTTATTAGCTCGCCATCTTGAAAGGCCCTTGCAACAATCTGAACGCTCGCCCGTTCGACGAGACTCAGATGAAGTAGCAGACaatgaggaagatgaagaagaTACCTTAGTAATAGATGAGGAGCCTGACCAGGAAAACAAGTCAGAAGATCATACTGCGGCGCGCCGTGCGGCAGCTGAAATCCTTATGGCTACATGCCAACAGGAAATGACTAAGGATTTCGACCTTAAAATCGCTGGGAACTTAATCAATAAACCTGTTCCTATTACCAATGATAAGACTGACTCTGGAACTAATTCAGTCTCGCCGACTCAGGAGTCACTGCCTATGCCTGTGGTGCCTACACGCAGCGATGAGGAAGAAGATGAAGAGGGTCTAGTCGCCTCCACAAGCGAGGGAAATAACTCTGGCAGTGATGAAAATAAaTCGGAAACGGACACAGCTCTTCCACCAAAAAAGAAGTCGGCTTACAGCCTAGCACCTAACCGTGTCTCATGTCCCTACTGCCACCGCAAGTTCCCCTGGTCATCATCCCTCCGTCGCCACGTCCTCACACACACTGGACAGAAACCTTTCAAGTGTCCACACTGCACACTTCTCTTCACCACCAAGTCGAACTGCGACCGCCATCTATTGAGAAAGCATGGAGGTTCCGCCAGAGCTATCCTGGCTGAGCCGATCCCTGATACCGTATCCCCACCACAGCCAATAAACGACACTAGAGCAGTGCCAGAAAGGCCTTACAAATGCGTTTCTTGTCCAACAAGTACGTTCTCATCGCTCGAAACATTGAAAAAACACATGTCTTCAAGACACGGGGCGGATTCTCAACCAGGCTCTCCAAACCCTGAAATTGTGgaagaaacaaatgaaggtGGTCTAGTCTTCAAATGCCATCTGTGCGAGGCGTCGTATGGAGACAGGAGTGGAGCCCTATCGCACTTGGCGACGGGACATACGGTAGAGTATGAACAGCTGGTCAGTAAGGGAGCCTTGGATGCAGCCAGTGACCGGAGCGAAAGCGCTGATGATGACGAAAGGGGGAAGTTTCCTGATCATGCTAACAGAAAGGTGGTCTGTGCCTTCTGTATCCGTCGATTCTGGTCTGCCGAAGACCTTCGTCGTCACATGAGGACTCATTCAGGAGAGAGGCCGTTTGCTTGCGACCTGTGCCGACGTCGCTTTACCCTGAAGCACAGCATGCTGCGACATCGCAAGAAGCACAGGGAAGAAATCACTGATGATGAGGAGGCTTCCCCACCTAACACGCCGCTTGAAGATGTTGTGACTAATGGATATCGCTACCAAGACGACGACGGCTCAGGCAACGAAATCCCGAGCAACGTCAATAACAACAACTCTCCTCCCTCCGCTCCGTACGAAAAAAAGCTCAAACTGGACATGACATCGCGCAAATACTCCTCAGAGGCCGAAAATGACCCGGAGAACAGCGACCTCATTGGTAAACTGCTCGGAATTCCCGACAAAACAATTAATAAGCTACTCTCCTCTGCAGACGAGGCTGCGAAAATTCTTGGCGTGAATAAATGA
Protein Sequence: MYSFVTEIKTEEVISEAKIEADAEMDGVQIEKQELRVTRTTSIDSDNRSDRSEEEDLRRARKRAASQSPSPIPMDKRTAKFECPKCRQRFDSVNAFDIHRFTAHSDDTKTGFDDLTFVDFSSKKFPEIARGVCEKNPHVSVTDQRYRCDMCFRDFPCGQALDIHRKSCLSTTRIPVSPERDRREDFFAKLDLRNRSFGIPGTLTPPMDRFTPKFDDNHLTNGIRHIDAARDLADIQSILNVTSAGGLLERLTGTRVSLESSVLTPPDTIIKDRDQEETQDNFAAEFRRMKLRGEFPCRLCPAKFPNLRALKGHNRVHLSGTGPGPYQCNMCPHASLDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHAKVTREDVKRSIIYHPSEDPNNDEVNSKLARDEVKRSLAFHTPDIDRRNESSGRDTPLTHFTPSFITDRHPVTNLTTKPLSLPLPESPLPLPMPRDVEQTQPRIKVKGIGQLTQIPEFRPPEITYKQNDISHDSYDEEAPVDLSTSDNNSCDVLDLSKKKRDTDSEEPKAPPRPSFEPDPASVAASAYEKTRFLLASQRLFENSLPKIDPSYYATQLSQLYAGTVPGIPGLPLPPSFPIAPYLLQPSFFPHPTDSQELAEIKQHIQKEIIRGLSMSGGRLVPNDQDSQPKIEPEEEELKPPPSISPIPSPHPESPRPPMNNTLVPQTDSVKMVIKNGVLMPKQKQRRYRTERPFSCSQCSARFTLRSNMERHVKQQHPQHWSVRRPAPRAPPPYPTPDSLTDRMKFALLARHLERPLQQSERSPVRRDSDEVADNEEDEEDTLVIDEEPDQENKSEDHTAARRAAAEILMATCQQEMTKDFDLKIAGNLINKPVPITNDKTDSGTNSVSPTQESLPMPVVPTRSDEEEDEEGLVASTSEGNNSGSDENKSETDTALPPKKKSAYSLAPNRVSCPYCHRKFPWSSSLRRHVLTHTGQKPFKCPHCTLLFTTKSNCDRHLLRKHGGSARAILAEPIPDTVSPPQPINDTRAVPERPYKCVSCPTSTFSSLETLKKHMSSRHGADSQPGSPNPEIVEETNEGGLVFKCHLCEASYGDRSGALSHLATGHTVEYEQLVSKGALDAASDRSESADDDERGKFPDHANRKVVCAFCIRRFWSAEDLRRHMRTHSGERPFACDLCRRRFTLKHSMLRHRKKHREEITDDEEASPPNTPLEDVVTNGYRYQDDDGSGNEIPSNVNNNNSPPSAPYEKKLKLDMTSRKYSSEAENDPENSDLIGKLLGIPDKTINKLLSSADEAAKILGVNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00961349;
90% Identity: iTF_01533483;
80% Identity: -