Llea025497.1
Basic Information
- Insect
- Lithophane leautieri
- Gene Symbol
- -
- Assembly
- GCA_949152455.1
- Location
- OX424487.1:5122870-5126575[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.0014 0.11 13.7 0.4 2 23 31 53 30 53 0.96 2 19 0.038 3 9.2 0.1 3 23 80 101 78 101 0.94 3 19 0.09 7 8.0 1.2 2 23 124 145 123 145 0.96 4 19 7.5e-07 5.8e-05 24.0 3.7 1 23 149 172 149 172 0.96 5 19 0.38 30 6.0 0.5 3 20 179 196 178 198 0.89 6 19 0.14 11 7.4 0.1 1 23 205 228 205 228 0.95 7 19 0.0023 0.18 13.0 1.8 1 23 235 258 235 258 0.97 8 19 2.4e-06 0.00019 22.4 1.1 1 23 263 285 263 285 0.98 9 19 3.3e-05 0.0026 18.8 2.6 1 23 291 313 291 313 0.92 10 19 0.00091 0.071 14.3 4.1 1 23 319 342 319 342 0.96 11 19 4.9 3.8e+02 2.5 4.0 2 23 369 390 368 391 0.92 12 19 1.3 98 4.4 6.7 1 23 465 487 465 487 0.95 13 19 0.44 35 5.8 3.2 1 21 491 511 491 514 0.94 14 19 0.61 47 5.4 0.2 1 21 519 539 519 540 0.94 15 19 2.6 2e+02 3.4 2.5 3 23 548 570 547 570 0.86 16 19 0.00069 0.054 14.7 2.7 1 23 577 600 577 600 0.96 17 19 0.67 52 5.3 2.5 1 23 605 627 605 627 0.95 18 19 4e-05 0.0031 18.6 0.8 1 20 633 652 633 655 0.94 19 19 0.00021 0.017 16.3 0.9 1 23 661 684 661 684 0.94
Sequence Information
- Coding Sequence
- ATGCGTCCGTTATCCATCGCGCGACGGAATGCAGAGACTATCGTCCTGAACGCCACGGTATACCCCTTCCGACTGCCGGACACAGCCCTCATGTGCGTATATTGCGGTGACAGCTACACCGACGCCACACTGTTTCGACAGCACATGAAGAAAGAACATTTCTCCTTCAAAGTCCGAACGGCTTTCGCTCATATTGCTTACGAGTGCTACCTCAAAATCGATTGCACAGAAATGGCGTGCAGAATCTGCTTTGAATCCTTCGCAAGAATTGACGATATTGCACGACATTTAAATGAGAGACATGACGCCAAAATCAACTTTGATTTCCAATTAGGACTACATCCCTACAGATTCTTACAAGACAGACTCATGTGCGGGATATGTGATCTAAACTTCCCCTGTATGCGACAGCTAAGTCGTCACATGTCTTCCCACTTCCAGAACTTCACGTGCGACACTTGTGGGAAGTCTTACACGACGAACAGCTCCTTGCAGCACCATATACGATTCACGCACATAGCAGCCGAGAGAATATGCAGAAAATGCAAACAGACGTTCAGTTCGTTAGAAGCTAAGAGAGAGCATACACTCAATTCTCCCAGCTGTTGGATGTATCAGTGTCTAGTGTGCCTAGAGCGATTCATGACATGGCCTGCCAAAGAACGACATTTAGTAATGGCTCATGGGCAATCCAGAAAGTCCTATTCTTGTTCCGAATGTAGTCTAACCTTTACAACTAGAAATGCCTATAGAGGGCATTTTAATACGACCCACGCTGAAGTGAACTTCCCTTGCGCGCACTGCGGACGGAAATTCGCCTCCAAAAGATATTTGGAACAGCACATGCTGGTCCACACAGGCATAAAAACGTTTCATTGCAATGTGTGCTCTAAATCTTTTCCGAGAAAGAAGAATCTTGTTCAGCACATGTGGACTCATAGTGATTCTAAGAGGTTTGAGTGCAGGTCTTGTAAAAAGCAGTTCAATCAAAGACATAGTTATAAGGCGCATATGAAAGAACCACATTTATGGGCGAAAGAGAACGCGGAGATTGTATTGCAATATTCAACCCTGTACCCATTCAGATTGCGAGGGAAAGCTATCACTTGCGTCTACTGCTGCGAAGGCTATGAGGACCCCACGCATTTCAGAAGACACTTCGACATCCACCACCAAGAGTTCACCATCGGCACGGCATTCCACCACATGAGTAGCTTAAAAGAATACCTCAAAGTCGATATCTGCAACCTAAAATGCAGACTGTGTTTCCAACCTTGTGAGAAAATCAATGATGTCGCTCAGCACTTGAAGGAGTCACATTCAGATGTTGCAAAGAAATTAAACCTCGAATTCGATATAGGTTTGCAGCCTTACAAACTGGTGAATAACAATTACTGCTGCTATCACTGCGGCAAGAAAATGCCCACTCTAATCAAGTTGTGCCGTCACACGATCTTGCATTACCAGCGGTTCACTTGCGACACTTGCGGTCGTAACTACCTCTCACACGAGGCTTTAAAGTACCATATTAAATGCATCCATGCAGTTACGAAACACGTGTGTAGGAAGTGCTGGACAGAATATCCCACCCTGGAGCAAAAGAAGGCACATGTTAGGGCATCAAAACCATGCTGGACTTTCTGCTGCATAGTCTGCGGGGACAGATTCCAATCCTGGGAACATAAGCAGAAGCATTTACAAGCAGAACATGGATACGAAAAGATAGTCTATAACTGTCCTGATTGTGAAGAAAAATTCACATCGAGAAAGTATTTTTATACACACTACAAGCTCTCACATACTGATGAAGGATTCCAATGCGCTTGCTGTGGACTCAAGTTTAATACGCAGAAACGATTAGATGACCACTCTCGCGGACATACTGGAGAGAAACAATTTATGTGCACCATTTGCTCCAAAAGTTTCATGAGACAGAACAGTCTGACGCAGCATATGTGGATCCACAGTGAAACCAAGAGATTCGTCTGTATTTTGTGTGAAAAGCAGTTTGCGCAAAAAGTTAGCTTGAAGACTCATATGAAGACCACGCATCCTGATGTTACTATTGATATTTAA
- Protein Sequence
- MRPLSIARRNAETIVLNATVYPFRLPDTALMCVYCGDSYTDATLFRQHMKKEHFSFKVRTAFAHIAYECYLKIDCTEMACRICFESFARIDDIARHLNERHDAKINFDFQLGLHPYRFLQDRLMCGICDLNFPCMRQLSRHMSSHFQNFTCDTCGKSYTTNSSLQHHIRFTHIAAERICRKCKQTFSSLEAKREHTLNSPSCWMYQCLVCLERFMTWPAKERHLVMAHGQSRKSYSCSECSLTFTTRNAYRGHFNTTHAEVNFPCAHCGRKFASKRYLEQHMLVHTGIKTFHCNVCSKSFPRKKNLVQHMWTHSDSKRFECRSCKKQFNQRHSYKAHMKEPHLWAKENAEIVLQYSTLYPFRLRGKAITCVYCCEGYEDPTHFRRHFDIHHQEFTIGTAFHHMSSLKEYLKVDICNLKCRLCFQPCEKINDVAQHLKESHSDVAKKLNLEFDIGLQPYKLVNNNYCCYHCGKKMPTLIKLCRHTILHYQRFTCDTCGRNYLSHEALKYHIKCIHAVTKHVCRKCWTEYPTLEQKKAHVRASKPCWTFCCIVCGDRFQSWEHKQKHLQAEHGYEKIVYNCPDCEEKFTSRKYFYTHYKLSHTDEGFQCACCGLKFNTQKRLDDHSRGHTGEKQFMCTICSKSFMRQNSLTQHMWIHSETKRFVCILCEKQFAQKVSLKTHMKTTHPDVTIDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00445450;
- 90% Identity
- iTF_00173464;
- 80% Identity
- -