Basic Information

Insect: Lithophane leautieri
Gene Symbol: ibtk
Assembly: GCA_949152455.1
Location: OX424475.1:5595269-5614829[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 4.9e-16 1.9e-13 51.3 0.0 7 80 486 558 480 566 0.91

2 3 3.8 1.4e+03 0.1 0.0 85 108 627 651 622 655 0.81

3 3 9e-14 3.4e-11 44.0 0.0 9 107 680 782 673 785 0.85

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	4.9e-16	1.9e-13	51.3	7	80	486	558	480	566	0.91
2	3	3.8	1.4e+03	0.1	85	108	627	651	622	655	0.81
3	3	9e-14	3.4e-11	44.0	9	107	680	782	673	785	0.85

Sequence Information

Coding Sequence: atgacggaCCAATACTCCAATGTAGAGTTGGCGGAGATGGTCTTGTATGCCATCAGTGGAGACAATGTATCTCGAGCCATCGAAATGTTCGCGGAGTTATTCCCCAATCGGCAACGTCCCTCACACAGGGTAATACTGACTGCTACGCAGAGACTGCGCGATCATCGGCAGTTCGACGTTCCCCAGCATGCTGAAGGTCGCGGCAACGAAGGCCTGCCTGTCGCCTTGCAGGAAGATATCCTGGAATTCTTCCGGCGAGAGCCACGGGCAAGCACGCGGGAGGCTGGTCGACGGTTTGGAGTGCACCACTCCACAGTGTGGCGGCtactgcacaaagaaatgcagcatccttttcattaccgcaagGTGTGCCTGGGCAAGTTCCACAGCGTGTGGCTGTGCGCGGGCGCGGCGTGGTGCTGCGGGCAGCAGGCGCGCGCGGGCGGCCCGCACGCCACGGCGCTGCGGCCCGCGCCGCTGCGGCTCAGCGAGCCGTGTGTCGCTGTCGCTATCACGTTGAATTCGACGGTGTTTCTGCTAGAAAGTGGAATgGTCCTCCAATACGCCCTCAACAGTACCGACAACATAACAAGCCAGTCCACCACTAAAACGCCATCGTCTATCAAGCTGGCCTCCATCAAGCCACTGATCAAGCTGTCAGAACCACTCGGCGTAAAAGGTGCGCGTGCGCACTGCGTCGTGTGGAACGTGCGTGCCGTGTACACGTGGGGAACAAACAATGGGCAGCTGGGGCATTCGAATGAGGATAAGTTTGTTGCTACGCCGAAGCGGGTGGCAATATCGATGAACAACAAGGAAGAAGCCGGTATTCAGCTGGTGGACGCGGCTGACGCGGCCACAGTGATCACGACGAGTCGCGGCGACGTGTACCTGCTGCACAAGTACATCTGCAAGAAGATTGCTATCAAACAAATAAACCTGCGTCAAGTGTGCGTAGAGGCTAAAGTCAACGATCAGGGCGTGTACTCACGAGTGACAGTACTGCTGCTCACCAACGTAGGACAGCTGTTCATATGGCAGGACACTACCAACAAACTTActagATGCGTATTCGGCCTCGTCCAccaaacaataataacaaacgTGGCACTCACCCATGACGCTCTCTACTTCACAACTAAATACGGCGAAGCCTTCATTGGCACGATCTCGCGCAAAACCACGCCCACCGCGCCGCCGCAGCCAATCAAGAAAGAGAAGGAAAGAGACAACAAGTCCTCCCTCGTCAAGTTTTTAGAAAAGGACGACTGTACGTCTGTCAGGATTGTGAAAATACCGAATGTTTATAGAGCGGTTTCTATTGCTGTGGATAGTGAAGGACTTAATTTTGCGTGTTTGCAGATAAAACCAACTTGCGGTCTGAAGTCACTACCACAGTTGTCGCCGACAAGTATGTCCAAACATATGGAATCTCTGCGTGAGTGCGCCTCCGAAGATGATCTGCTACATGATGTAGTGTTCAAGGTCGGCACAAAACTCTTCCCCGCGCACATTTTCATCGTAGCCTCTAGCAGCGAACTGCTTTACAAACTCTACCAGGACAACGTAACAGCCGCGGGCGATAAACCCGAGGTCACACTGGACAACGTGCACCCTGAAGCGTTCGAGAGAATCATGAAGTTCATGTACACTGGCACTTGCGATGTCACGGAGTTGGGACCTTGTGGACTTAAGATTACGAAGGAAGAATTGGTGAAGAAGGAGAAGGATTGTGATGAGGAAGAAGAGTTGGTTGAAAACCCATCGGAAATATCAGCCTTCGAAGTATACAACAAACCTCTGGACAAGTCCAAGCGTCATCGCAACCGACGCAACACGGACACTCCGCCACGCACCCATCTTTATTGTGACCCCGTCAAACTTCTGCAAGCCTCGGCTAAGCGACTGCAGGTCATGAGTCTTCACAAACTGCTTGAGAAGTTCTACTACAAGAACGGCTCAATATGTCTGAAAGAGAGCGCGAGCACGAGTTACACCCGCAACCCGTGCCCTCTCTGGGAGCGCGAGTCGTTTCCCGAGCTAGTCGACACGAGTGTCGTGTCTAAGGACGGCGCGAGAGTGCCCGCGCACAAGTGTGTACTCGCGGCCAGGCTTGAGTACTTCCAGGGAATGTTTATGCATTCTTGGACAGAGaGCAAGATGTTGTCAACAGTAACTCTTCCTATAAACTACGGCATCCTACTGCCGGTCATCAACTTTCTATACACCGACTCTTGCCCTGAACTAGAAAACTGTGACAGCATCGACTTCATATGCAACCTCCTTATAGTCGCCGATCAGCTGTTCATATCACGACTGAGAGAAATGTGTGAGATCGCACTAGCAAACTTAATTAACCTGAAAAACTGCACAGAACTCTGCCAGTTCGGACACACGTACAACGCAACACAGCTCAAACAATGCTGCATGGAATTCATCGCACTAAATCTCAACAGTGTCTTGGAAAACAGATCTTTAGATCTACTAGAAGAAACTTTACTGAATGATATAACTCAGTATTATTGCAAGTTCAACCCAATCATGTCTTCCAGAATAATCACTCCATTCTACAACGCTCCAACCGATGAAGTTATTGAGGAATTCGCCAAAACACATCCAGTAAACTTGGAGGTAACGGATGAAGATATTAAGAAAGATGATAGTATAACAGaaatagtaaagaagaaaaagGGAAGGAAAATCGAATACACTGACAATGAGAAGGAGAGAATGAGGTACGAATCTGTGAGCTCGGTGACGTCATTGGACCTGTCTAATGATACCTCCGGTGATATAACGCTATCTTTGAGTAAGATATCTAAGGAATCTGAGAAGGAAACGCGGGATAAGAAGGAAAAGTGGACCGAAGTACCATCCTCGCAGCAGAAACAACTGAAGGTCGTCCAAGCAAGACTGAAAGCCATAAACATTGCGAAAGATTTACTGAGTGAAGCGCCCACCGAATCATTTACTAAACTCACGAAAAGTAGTTCTTCGAGTGCCGTGACAATACAAGAAAAAATGCCTAGTTTACCTACCTCATCACGAATGTCAGTCTCACCGAAAGATTCTCCTATCAATGAATCTGCTTGGAGTCCAAAACAGGGTAACGTAGTTATAAGTCATGTGGGACCAAAACTATCTCAGAAGCAAAGAAAAAAGTTAGCATTACAAGGAAATGAAACAGCATCACAAAGCATTGATGATTACTTTACTAAGATAAATGTGGGTAGTCCTCCTGAAAAGCCGAAGAATCCATGGAAGATCTGTGGGCCACCGGTTGCTAGCAGTAGCCCTAAATCGAAAGTTATAGAGTTTAATAAGATATTGACTGACCAAAGGAAACAGAAGGAAGATCACTCGAGAATCATGACCAAGCCACTCCTTATGACACAGCTTGAAGACAAAGCTATAGAGCAATTGGAGAGATTCTACAACATCCATGAAATAGATGATGAGTTGATTACGGTGCGACGTATAGAGCTGCAAGTGTCTTCTCCACAATGGTTACACACTGCCCCTAAGTGA
Protein Sequence: MTDQYSNVELAEMVLYAISGDNVSRAIEMFAELFPNRQRPSHRVILTATQRLRDHRQFDVPQHAEGRGNEGLPVALQEDILEFFRREPRASTREAGRRFGVHHSTVWRLLHKEMQHPFHYRKVCLGKFHSVWLCAGAAWCCGQQARAGGPHATALRPAPLRLSEPCVAVAITLNSTVFLLESGMVLQYALNSTDNITSQSTTKTPSSIKLASIKPLIKLSEPLGVKGARAHCVVWNVRAVYTWGTNNGQLGHSNEDKFVATPKRVAISMNNKEEAGIQLVDAADAATVITTSRGDVYLLHKYICKKIAIKQINLRQVCVEAKVNDQGVYSRVTVLLLTNVGQLFIWQDTTNKLTRCVFGLVHQTIITNVALTHDALYFTTKYGEAFIGTISRKTTPTAPPQPIKKEKERDNKSSLVKFLEKDDCTSVRIVKIPNVYRAVSIAVDSEGLNFACLQIKPTCGLKSLPQLSPTSMSKHMESLRECASEDDLLHDVVFKVGTKLFPAHIFIVASSSELLYKLYQDNVTAAGDKPEVTLDNVHPEAFERIMKFMYTGTCDVTELGPCGLKITKEELVKKEKDCDEEEELVENPSEISAFEVYNKPLDKSKRHRNRRNTDTPPRTHLYCDPVKLLQASAKRLQVMSLHKLLEKFYYKNGSICLKESASTSYTRNPCPLWERESFPELVDTSVVSKDGARVPAHKCVLAARLEYFQGMFMHSWTESKMLSTVTLPINYGILLPVINFLYTDSCPELENCDSIDFICNLLIVADQLFISRLREMCEIALANLINLKNCTELCQFGHTYNATQLKQCCMEFIALNLNSVLENRSLDLLEETLLNDITQYYCKFNPIMSSRIITPFYNAPTDEVIEEFAKTHPVNLEVTDEDIKKDDSITEIVKKKKGRKIEYTDNEKERMRYESVSSVTSLDLSNDTSGDITLSLSKISKESEKETRDKKEKWTEVPSSQQKQLKVVQARLKAINIAKDLLSEAPTESFTKLTKSSSSSAVTIQEKMPSLPTSSRMSVSPKDSPINESAWSPKQGNVVISHVGPKLSQKQRKKLALQGNETASQSIDDYFTKINVGSPPEKPKNPWKICGPPVASSSPKSKVIEFNKILTDQRKQKEDHSRIMTKPLLMTQLEDKAIEQLERFYNIHEIDDELITVRRIELQVSSPQWLHTAPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042779;
90% Identity: iTF_00851943;
80% Identity: -