Basic Information

Gene Symbol
-
Assembly
GCA_963978505.1
Location
OZ021682.1:5530987-5533539[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00047 0.034 14.5 3.9 1 23 328 350 328 350 0.98
2 15 0.0014 0.1 13.0 4.0 1 23 356 379 356 379 0.98
3 15 2.8e-05 0.002 18.4 1.6 2 23 477 498 476 498 0.97
4 15 2.3e-06 0.00016 21.8 1.6 1 23 504 526 504 526 0.98
5 15 0.0026 0.18 12.2 0.8 1 23 532 554 532 554 0.98
6 15 3.6e-06 0.00026 21.2 1.3 1 23 569 591 569 591 0.98
7 15 6.7e-06 0.00048 20.3 1.2 3 23 599 619 597 619 0.98
8 15 2.4e-05 0.0017 18.6 1.5 1 23 625 647 625 647 0.97
9 15 0.00082 0.059 13.8 0.2 1 23 653 675 653 675 0.99
10 15 6.3e-06 0.00045 20.4 0.3 1 23 681 704 681 704 0.94
11 15 1.9e-05 0.0013 18.9 1.3 1 23 710 732 710 732 0.98
12 15 0.00041 0.029 14.7 4.7 1 23 738 760 738 760 0.98
13 15 6.1e-06 0.00044 20.5 0.2 1 23 766 789 766 789 0.96
14 15 4.9e-06 0.00035 20.8 0.9 1 23 795 817 795 817 0.97
15 15 3.6e-06 0.00026 21.2 4.5 1 23 823 845 823 845 0.99

Sequence Information

Coding Sequence
ATGTCTGATGCTCCTTCTGCATCTGTGCAGCAAGGAATGTCTCATGGGATCAGAGTCGTGAACAGGCTGGGGATGATAAATAAAGAAGGACAGACCGATCCTTGCGGCAAAAGTATTTCTTGTGGTAACAAGACAGAAACTGCTAACGAAACTCACTGTCGTGTATCACCAATGGGGATAAATCATCGAACTCAAATAGACGTAATTAATATgcaagagaaaaattcaaaggtcTACAATAATCTATTGATATACGAAGAGCAATACTCGAAATTTGTAATTCTTAGGGCTCTGAGGAGCTCTGATCCTGGTGAAGTAGCCTCTGAGCTTGCTGACATAGTAACGACGATTGGTGCGCCACGAATAATTCAGAGTGGCAATGGTCGCGAGTATGCGGAGCAAGTCGTACGGGAGATTCGTAGATTACTGAGAGACTTTTGCGTCGTACATGGTGATGCCGCAAAAAACAGTGATGCACGCCGAGATTTCAGGAGGATAGTCAAATCATGGTTGGAGAAGAATCCTGGTAAATCTTGGTACGAGGGTCTGAAAACACTTCAAGTTGTTGAAAATACGTCCATCAATTTGCAAAATGGTACGATCCCAAGTCAACTCTTCTTTGGTAGAAATGTTTGCGATGATTTGCGACGAACCATTGGAGGCAAAGGATTAGTGGGTAATACAGCATCAGAGGAGGATTCGTTCTCAGCTGTCTTGAGTGCACACAATTCATATGCTTCTTTGAAAAAAGATCCATGCCAGGTTTCTATTGCCAGAGCAATGGATATCACTAAGGAAAACGACAGTCACTGCAAAAGCATAGAGTGCAGAGCACAGACcaacgataaatcgtcgtCAGCAAAAGAAAACGTTAATAGCTTCAATTTTGTGAGCATCAAGAGTGAGCTGCCAAATATAACAGACAGCGTTACAGAGGTCCATTCCGAGAAAGAGAAACGCATTgattctgaaaaatataacttCAAATGCAAAATATGTCAAAAGCAATACATGAAGCTTGGTCATCTACGAAATCACACGAGAGCCCACACAAACATTGGAAAATACGAATGCTCAATCTGCTGCAAATCATTCAGGTCATCGAGTCTCCAAGCTAAGCAtatgcagagatttcatgaAGGTGACAAAAACCTGACTGTCGGTGAGAGTACAAGGTCGGAAGACAAAAAGGGTGACCATGAAAGTAACAaaaagaggaataaaaaagatgAGAAAATTAGTCGTAAAAGAAGATTTGTGTTAGAAAAATCCAAGGGAAACAAATCTATGCCGGGTGAGGCGTGGAAAACATCACTGTCAGTACCATTATCCAGAGTTTCAACAAAAAGTCCATCTAAACGGTCAAACTGTGTTTTCAGGAGAAAAATCAGTAACTCATTAACCAAAGTTAACAGTAATCCTTTGCTCGAATGTACCTACTGCAAGCGAAAATTCAACTTCCCTAGTGTGCTGAAGAGACATGTGCGTTCTCACACGAATGAGAGACCCTACGTTTGCCAGGTGTGTGGCAAGAGTTTCAAACAGCTTGGTCATCTCAGCCAGCACTCTCTAACTCACACGGATTATCGTTCATTCCAGTGTACGATGTGCAACATACAATTCGAGTCACTAGAGGCGTTTAAGCTTCACTCCCGGTTGCACAAGAACGAAGCTTTCTTCAGGTCCAAGGAGACTTATCGGCTTTTCGAATGTGATAGTTGCAAAAAGGTATTCACCACAAAAAGTGTCCTCGAGCGTCACATATTCACTCACAGCCATGAGCGCCAGTTCGGCTGCAAGGTGTGCGGTAAAAGATTCAAACAAGCGGGTCATGTCAAGTCGCACATGCTTGTGCACACTGGTGAAAGAAAGTTCGCCTGTACCGTGTGCTCGAAGAGATTCAGCCTTTCAAATTCACTAAAGAAACACATGTACGTTCATAATGGTGAGAAACCATACCAGTGTGACGTGTGCGGTGCGAGATTTCTCGAAAAGCGTAATCTCAACGGTCACCTCATGACTCACACAAATGAGAGGCctttttcatgcaaaatttgCGGCAAGCGCTATACACTAGCGGACACTCTTCGTCGTCACATAAGTGCCGCACACGAGGATGGACGTACATATCAATGCGAAATCTGTGCGAAAATGTTCAAGCAACTAGCTCACCTATCAGTTCACAAAAAGGTCCACAACGACGAGAGACCGTTTCAATGCCATCTCTGCGAGAAGAACTTCAAGCACAAGAACGTACTCAAGTCACATCTGGCTATCCACGCCAACGTCAGGCCTTTTGAGTGCGACGTGTGCAAAGCCACCTTCGTACGTAAGACTAATCTTCAGACTCACATAGCTTCGGCTCACATGAACGAACGTCCGTACGTATGTACAATTTGCAACAAACGCTTCAAGCAAATAAGTCATCTGAACGGTCATATAGTAGTTCACAGCAACTCTATGCCTTATCAGTGCGATTTTTGCGATCGTCGATGCAACAGACTCGATAATCTAAAGAAACACATGAGATtgcatacgaaaaataaagaatag
Protein Sequence
MSDAPSASVQQGMSHGIRVVNRLGMINKEGQTDPCGKSISCGNKTETANETHCRVSPMGINHRTQIDVINMQEKNSKVYNNLLIYEEQYSKFVILRALRSSDPGEVASELADIVTTIGAPRIIQSGNGREYAEQVVREIRRLLRDFCVVHGDAAKNSDARRDFRRIVKSWLEKNPGKSWYEGLKTLQVVENTSINLQNGTIPSQLFFGRNVCDDLRRTIGGKGLVGNTASEEDSFSAVLSAHNSYASLKKDPCQVSIARAMDITKENDSHCKSIECRAQTNDKSSSAKENVNSFNFVSIKSELPNITDSVTEVHSEKEKRIDSEKYNFKCKICQKQYMKLGHLRNHTRAHTNIGKYECSICCKSFRSSSLQAKHMQRFHEGDKNLTVGESTRSEDKKGDHESNKKRNKKDEKISRKRRFVLEKSKGNKSMPGEAWKTSLSVPLSRVSTKSPSKRSNCVFRRKISNSLTKVNSNPLLECTYCKRKFNFPSVLKRHVRSHTNERPYVCQVCGKSFKQLGHLSQHSLTHTDYRSFQCTMCNIQFESLEAFKLHSRLHKNEAFFRSKETYRLFECDSCKKVFTTKSVLERHIFTHSHERQFGCKVCGKRFKQAGHVKSHMLVHTGERKFACTVCSKRFSLSNSLKKHMYVHNGEKPYQCDVCGARFLEKRNLNGHLMTHTNERPFSCKICGKRYTLADTLRRHISAAHEDGRTYQCEICAKMFKQLAHLSVHKKVHNDERPFQCHLCEKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHIASAHMNERPYVCTICNKRFKQISHLNGHIVVHSNSMPYQCDFCDRRCNRLDNLKKHMRLHTKNKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00058119;
90% Identity
-
80% Identity
-