Basic Information

Insect: Lissocephala sabroskyi
Gene Symbol: Hr39
Assembly: GCA_037075105.1
Location: JBAMCP010000671.1:1665-4339[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.53 3.7e+03 -2.4 3.0 119 153 226 259 120 302 0.43

2 3 5.2e-20 3.6e-16 60.2 1.1 1 151 434 581 434 591 0.69

3 3 3.5e-81 2.4e-77 261.7 0.3 184 408 580 795 576 795 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.53	3.7e+03	-2.4	3.0	119	153	226	259	120	302	0.43
2	3	5.2e-20	3.6e-16	60.2	1.1	1	151	434	581	434	591	0.69
3	3	3.5e-81	2.4e-77	261.7	0.3	184	408	580	795	576	795	0.96

Sequence Information

Coding Sequence: ATGCCCAACATGTCGCTCATAAAAGCGGAGCAGAACCCGCCGAtcccacccaccgccaccaacgGCAGCTCGCGACACAATGTCTCCGTGACGAACATCAAATGCGAACTGGACGAGCTGCCCACGCCCAACGGGAACATGGTGCCGGTGATTGCCACCTACAACGGCCTGAGGATcccgctgggcggcggcgggaaggCCGACGAGTCGGATTCCGAGGCCGAGCTGACGAACATTGAGAATTTGAAAGTGCGCCGGCGCACGGAGGTGATGGGCCCGCGGCCCATGTCCTGGGAGGGCGAGCTGAGCGAGCCTGAGGCCCACGAGGCCGAGCTCATGGACACGGACACCCTGAGCAACGGGGccgagccgccggcggccaaggACGAGCTGGCCACGCCGGCTGTCCAGCTGCAGCCCATCAAGACCGAGCTGGAGCAGATTGCCGGGGAgatgcggcagcagcagcaggcgaagGTCTACGGGCCGCCGACGGCCAGCGCGCCGGCCAAGCTCAAGCTGGCGCCGACCCAGAGTGATCCCATCAATCTCAAGTACGAAccggccgtgggcgtgggagCAGGTCCTTTGGCTGGAGACAACTCGCCTTTGTTGACGGCCCGCCACAAGTCTAGCAGTGGAGGGCatttgccgctgcccgccAATCCGAGTCCAGATTCCGCCATACATTCCGTGTACACGCACAGCTcgccgtcgcagtcgccgctgaCGTCGCGCCACGCCCCCTACACGCCCTCGTTGAGCCGGAACAACAGCGACGCCTCGCACAGCTCCTGCTACTCGTACAGCTCGGAGTTCAGTCCGACGCACTCGCCGATTCAGGCGCGGCATGCCCCGCCGGCCGGGGCTCTCTTCCCCGGCACGCCCACGGGCTATGCCACCAATGGGGGCCTGCACCACCACAGTGTCCTGTACCGGCCTTTGAATGTAGAGCCTGGTGGCGGCCAGGAGGCCCAGAACCTCAGCATGGACGCCAGCAGTGCCGGCAGTGGCCCCGGGGCGGCCTTCGATGGCAGTAACTTGCCTGCCTCGCCGGCGGGCATCTCCCGCCAGCAGCTGATCAACTCCCCCTGCCCCATATGCGGCGACAAGATCTCCGGCTTCCACTACGGCATCTTCTCCTGCGAGTCCTGCAAGGGCTTCTTTAAGCGCACCGTCCAGAACCGCAAGAACTACGTCTGCGTGCGCGGCGGGCCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGCCCGGCCTGCCGGTTCGAGAAGTGCCTCCAGAAGGGCATGAAACTGGAGGCCATCCGCGAGGATCGCACTCGTGGCGGACGCTCCACCTACCAGTGCTCCTACACGCTGCCCAACTCCATGCTCAGCCCGCTGCTCAGTCCCGACCAggcggtggccgtggctgccgctgctgcggtggtcaaccagcagcagcaccaccagcagcagcagagactCCAGCAGCATCCGCTCAATGGCTACGCCAATGGGTCGAGCTCTCTGCCCGGCAGCCCCAGCCTGGGGGCGGTGACCATCAAGACGGAGCCCGTGGAGCAGCACACGCCGCGGGCGGCCAGCATACCAGCCCTGCTCCAGGAAATCATGGACGTGGAGCATTTGTGGCAATACACTGAGGCCGAGTTGGCCCGGATCAATCAACCGCTTTCTTCCTACTCAACTTCCGGCTCGACTTCGGCGTCGTCTGGGGCGGCCAACGCTGGCCAAGGACAGCAAATGACGAACCCACTGCTGGCCAGTGCCGGTCTCTCATCCAACGGCGAGAACGCCAATCCCGACCTGATCGCCCATCTCTGCAATGTGGCCGATCACCGGCTCTACAAGATCGTCAAATGGTGCAAGAGTCTTCCCCTCTTCAAGAACATTTCGATCGATGATCAAATCTGCTTGCTCATCAATTCGTGGTgtgagttgctgttgttctccTGCTGCTTTCGCTCCATAGACACTCCCGGCGAGATCAAGATGTCCCAGGGCAAGAAGATCTCCCTCAACCAGGCCCGATCGAATGGCCTGCAGGCCTGCGTGGAGCGCATGCTGAACCTCACGGACCATCTGAGGCGCCTGCGCGTGGATCACTACGAATACGTTGCCATGAAGGTTATCGTCCTGCTGCAATCCGATACCTCGGAGCTGCAGGAGCCTGTGAAAGTGCGCGAGTGCCAGGAGAAGGCTTTGCAGAGCCTGCAGGCCTACACGCTGGCCCACTACCCCGACACACCGTCCAAGTTTGGCGAGCTGCTGCTCCGCATTCCCGACCTCCAGCGCACCTGTCAGCTCGGCCGCGAGATGCTGACGAACAAGTCCAGGGACGGCGCCGACTTCAatctgctggtggagctgctgcgcgGAGAACATTGA
Protein Sequence: MPNMSLIKAEQNPPIPPTATNGSSRHNVSVTNIKCELDELPTPNGNMVPVIATYNGLRIPLGGGGKADESDSEAELTNIENLKVRRRTEVMGPRPMSWEGELSEPEAHEAELMDTDTLSNGAEPPAAKDELATPAVQLQPIKTELEQIAGEMRQQQQAKVYGPPTASAPAKLKLAPTQSDPINLKYEPAVGVGAGPLAGDNSPLLTARHKSSSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGALFPGTPTGYATNGGLHHHSVLYRPLNVEPGGGQEAQNLSMDASSAGSGPGAAFDGSNLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAVAVAAAAAVVNQQQHHQQQQRLQQHPLNGYANGSSSLPGSPSLGAVTIKTEPVEQHTPRAASIPALLQEIMDVEHLWQYTEAELARINQPLSSYSTSGSTSASSGAANAGQGQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGKKISLNQARSNGLQACVERMLNLTDHLRRLRVDHYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGREMLTNKSRDGADFNLLVELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00904793;
90% Identity: iTF_00904793;
80% Identity: iTF_00904793;