Lnew001777.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Liometoxenus newtonarum
Gene Symbol
egg
Assembly
GCA_030264535.1
Location
JARJEB010002926.1:1793-5797[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 3.8 9.6e+03 -3.4 0.0 31 39 551 559 541 562 0.76
2 2 2.5e-10 6.3e-07 29.3 0.1 7 73 594 654 591 658 0.88

Sequence Information

Coding Sequence
ATGTCGGCATTAGTTATGAGTAGCAACGATGAAAAGTCTTCAAACGATATAATCGTCTTGGACGATGACGATAACATGGACACGATCAAACGTACCAATTGTATTAACTATTTATGCAAGAGTGGTTTGGAGCTTATGAAACCTCCAGTATTCTGTTCGTCATATTTCCGGATTAAAGGCAAAGCGAACGGCCAGCAGGTATGCAAAGCTTGCTTTGAGATTGCAGCCAACCATTTTGAACTTTTAAGCGACGCGCTGAAAGATGGCAAAGATCTTCTATCCATCTCACTGCCAAAAATACACGAAACAGTTGCCTTGGACTCGGACTCCGACGATGAAGATGACGAAGGTGAAGGCTTGCTTGATGAAACCACGAGGGAGTTCTTGGCGGAACACTTGAACGAAGTCCTTGAGGACTGCAACATGAAGTACGACTGTGCGAATATAATGGAAAACACCTTGAAGGAGCTTAATCAGCGAGTGAACGCAACTAGTGATTCCCTTTTGGAAGTGAAAACAATGAGCGACAGCGTCCGCAAAGAATTCGACTTAATGCTCTATACACTTTCGAACGCTTTGCGCGTTGACAACCGAGAACAGCCGGAATTAATGGTGTACGACGAAGCGGATGCGATACCTTCACCTCCTCAGCAACAAAACGTGCCGGCGATGCCGTTGTCGCAGCCACCAACAAACCTCCCGAAACGTGCCCCATTGATACGTCCATTGCTACGCATCAATCAGTTCTACTATGCCCGGAAAACGGATGCCGGCCTTGCCTCCTGGGTGAAAGTGAAGCTGGAGAATATCATCCCGCCCGGATCGAAAATCAACGACATACTTCTACGAGTAACAATGTACCAGGTGTATCGAGAGGTCGGCGGTCGTGAGACACGTCGTTTCGTCGACGGTAGATCCATCGCGTACAGCGCCCCGCTTTCGACTATGCTGGAAATCGGAACACGTGTCATTGCGCTGTTCCACGACACGCAAACGAAGAAGGGCGACAGTTACTATCCGGGTATCGTCGGGGAATTCCCGTCCGCGTTCAACAACTTTCGTTATTTGATCTTCTTCGATGACGGCTACGCGTTCTACGTGGATCACAATGATGTCTTCATGATTTACGAATGTTCGAAGGATGTCTGGGATGATGTGTACTTCGAATCGCGAGCGTTTATCAAAAAGTATCTCACCGAGTATCCGAACAGGTCCATGGTGAAGTTGCTTAAGAACCAAACAGTTCGGACGGAGTATAAAGGCAAATGGTACATGACCACTGTCCTCCAGGTCGATTGCTCACTGGTGCAAATGTATTTCGGTATGATCCATCGCACCGAATGGATTTACCGCGGGTCGAGGCGGTTGAACACGATGTATCAAGAGGAACAAGCCGCAAGCAACCGATTGCAACATAAACAGAGGAATGCTAGGGCTAGGAATCGACCCGCCAATGTTACAGGAGCTCCGTACGTTCAATACAGTTCAGTCCGCGATGATTCAGATGTGGTTTTCGTGTCGCAAGGTCCTCTCGAAAAGCCCGAACAACGTGCGGTGGCGAAAAAAAGCACTCGCCCTCCGCTTCCTTCATCAATCGACTCTTCATCGGAAAGATCTGCAAATAGTGTTCAACGTGAAGAGACAACGCCTGGAAAAATTGTCTACTACACTCCACGCAAACAGTGCCCCACGAAGAAAATCTACGTGCCGCACAAATGCAGCCCGCTGTGCCAGCAACAATTGCAAGCAACTTTGAGTCGACTCAAGGGCTACGGCCCACTGGCGAAACCGCTACTGTGCGGCTACCATCGCATTCACTACAAGGCCAAGTCGCGACGACCTTTCATCATCTACAAAACGCCGTGTGGCCGCACGACGCGCAATATAGGCGAACTCCATCAATATCTGGAAATGACCAAAAGCGATTTCAGTGTggatttgttcaatttcgagcCATGGGTACGCTGCCTCGCCGAATTCATACTTGAACCGAACGCGATTTTGAACAAGGATCTTTCCGACGGACAGGAGCAGATACAAGTACCGGTGGTTAATTACATCGATGGCCGGACGAATGATTTCGTCAATTATTCCACGCGGCGGATGCCGATGGAGGGTGTCAACTTGAATCTCGATCCGGAGTTTTTGTGTGGCTGCGACTGCGAAGACGATTGCGCcgataaaacaaaatgtgCATGTTGGCAGCTGACCCTCGAAGGATCCAAGTATCTGTATAAGGATGGTGATCTTAAAGATCCACTCGATGTAGGGTATGAGTATCGACGGCTCATGGAGCCGCTGATTACAGGCATCTACGAATGCAATTCGCGCTGTAAATGTTCCAAGACTTGCTTGAATCGCGTGGTGCAAAACCCGCTACAGCACAAACTGCAAATATTCATGACGAGTAACCGTGGCTGGGGGATACGGTGCATTAACGATATACCGAAAGGCGCTTTCATTTGTATTTACGCCGGCTCGTTGTTAACCGACGAGGCGGCAAACGAGGGGGGACAAAATGTTAGCGATGAATACTACGCCGAATTGGATTTCATTGAGTCCGCAGAACTGATTAAGCAAGATTACGAAGAGGAGGCGTATAAAAGTGAGGATGAGAGTACGCCGACGGCGCCTACAAATCGAATATTTGATAATGGCAATAGTGCCGGCAAAAAGGTTCTGATTACCAGTGCTGGTAGTAAAAGTAATACTGGTTCAACCACAAGTCTCACTGACAATACTCAAATTCAAACATCGAGTGTTGGAGATGCTGTGGAGATGGGTGCTGCCCAAGAAGAGGAATCTATTAGAAGCCGTTTGAGAAAGAGGGacgttgaaattaattataagaaaatgcaGGATGATGCTGTTAATATAAGTGATGAAGAAGATGTCCGTGAACCGTCAAGTTTCAACCCGAAAGAAAGCGATATTGGAGCAGCAGCGGTAAGTCGCTATCCTTCGGTTCGCACCATGTTTGGCAAGAACGAAAGCGTTTACATTATGGATGCCAAATGTACTGGTAATTTGGGACGATTTTTAAATCACTCATGTTCGCCGAATGTATTCGTACAAAACGTGTTTGTCGACACGCATGACTTGCGATTTCCATGGGTATCGTTCTTCGCGATGCAATTCATCCGTGCCGGCACTGAACTCACATGGAATTACAACTATGACGTTGGGAGCGTTGAAGATAAAGTGCTTTATTGCAACTGTGGCAGTCCGGATTGCAAAGGGCGTTTACTCTAA
Protein Sequence
MSALVMSSNDEKSSNDIIVLDDDDNMDTIKRTNCINYLCKSGLELMKPPVFCSSYFRIKGKANGQQVCKACFEIAANHFELLSDALKDGKDLLSISLPKIHETVALDSDSDDEDDEGEGLLDETTREFLAEHLNEVLEDCNMKYDCANIMENTLKELNQRVNATSDSLLEVKTMSDSVRKEFDLMLYTLSNALRVDNREQPELMVYDEADAIPSPPQQQNVPAMPLSQPPTNLPKRAPLIRPLLRINQFYYARKTDAGLASWVKVKLENIIPPGSKINDILLRVTMYQVYREVGGRETRRFVDGRSIAYSAPLSTMLEIGTRVIALFHDTQTKKGDSYYPGIVGEFPSAFNNFRYLIFFDDGYAFYVDHNDVFMIYECSKDVWDDVYFESRAFIKKYLTEYPNRSMVKLLKNQTVRTEYKGKWYMTTVLQVDCSLVQMYFGMIHRTEWIYRGSRRLNTMYQEEQAASNRLQHKQRNARARNRPANVTGAPYVQYSSVRDDSDVVFVSQGPLEKPEQRAVAKKSTRPPLPSSIDSSSERSANSVQREETTPGKIVYYTPRKQCPTKKIYVPHKCSPLCQQQLQATLSRLKGYGPLAKPLLCGYHRIHYKAKSRRPFIIYKTPCGRTTRNIGELHQYLEMTKSDFSVDLFNFEPWVRCLAEFILEPNAILNKDLSDGQEQIQVPVVNYIDGRTNDFVNYSTRRMPMEGVNLNLDPEFLCGCDCEDDCADKTKCACWQLTLEGSKYLYKDGDLKDPLDVGYEYRRLMEPLITGIYECNSRCKCSKTCLNRVVQNPLQHKLQIFMTSNRGWGIRCINDIPKGAFICIYAGSLLTDEAANEGGQNVSDEYYAELDFIESAELIKQDYEEEAYKSEDESTPTAPTNRIFDNGNSAGKKVLITSAGSKSNTGSTTSLTDNTQIQTSSVGDAVEMGAAQEEESIRSRLRKRDVEINYKKMQDDAVNISDEEDVREPSSFNPKESDIGAAAVSRYPSVRTMFGKNESVYIMDAKCTGNLGRFLNHSCSPNVFVQNVFVDTHDLRFPWVSFFAMQFIRAGTELTWNYNYDVGSVEDKVLYCNCGSPDCKGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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