Basic Information

Insect: Liodrosophila aerea
Gene Symbol: L
Assembly: GCA_035045005.1
Location: JAWNNL010001440.1:53746-65088[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00077 19.9 2.9 1 23 159 181 159 181 0.98

2 17 0.36 26 5.6 6.2 1 23 187 209 187 209 0.97

3 17 1.7e-07 1.3e-05 25.5 3.2 1 23 215 237 215 237 0.99

4 17 1.3e-05 0.00094 19.6 0.4 1 23 243 265 243 265 0.99

5 17 0.71 52 4.7 0.6 2 23 340 366 339 366 0.78

6 17 0.0011 0.084 13.5 0.2 2 23 400 422 399 422 0.95

7 17 0.063 4.7 8.0 0.7 1 23 499 521 499 521 0.97

8 17 0.019 1.4 9.6 0.1 2 23 529 550 528 550 0.91

9 17 0.0014 0.1 13.2 0.0 1 21 558 580 558 583 0.88

10 17 5.3 3.9e+02 2.0 1.6 2 23 619 641 618 641 0.95

11 17 0.0026 0.19 12.4 1.1 1 23 688 711 688 711 0.97

12 17 0.0017 0.12 13.0 1.8 2 23 881 903 880 903 0.96

13 17 0.12 8.7 7.2 0.1 1 23 909 931 909 931 0.92

14 17 0.55 40 5.1 0.7 2 23 939 960 938 960 0.95

15 17 0.41 30 5.4 1.2 1 23 1050 1072 1050 1072 0.94

16 17 0.032 2.4 8.9 0.0 1 23 1082 1104 1082 1104 0.96

17 17 0.00023 0.017 15.7 1.2 1 23 1109 1131 1109 1131 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00077	19.9	2.9	1	23	159	181	159	181	0.98
2	17	0.36	26	5.6	6.2	1	23	187	209	187	209	0.97
3	17	1.7e-07	1.3e-05	25.5	3.2	1	23	215	237	215	237	0.99
4	17	1.3e-05	0.00094	19.6	0.4	1	23	243	265	243	265	0.99
5	17	0.71	52	4.7	0.6	2	23	340	366	339	366	0.78
6	17	0.0011	0.084	13.5	0.2	2	23	400	422	399	422	0.95
7	17	0.063	4.7	8.0	0.7	1	23	499	521	499	521	0.97
8	17	0.019	1.4	9.6	0.1	2	23	529	550	528	550	0.91
9	17	0.0014	0.1	13.2	0.0	1	21	558	580	558	583	0.88
10	17	5.3	3.9e+02	2.0	1.6	2	23	619	641	618	641	0.95
11	17	0.0026	0.19	12.4	1.1	1	23	688	711	688	711	0.97
12	17	0.0017	0.12	13.0	1.8	2	23	881	903	880	903	0.96
13	17	0.12	8.7	7.2	0.1	1	23	909	931	909	931	0.92
14	17	0.55	40	5.1	0.7	2	23	939	960	938	960	0.95
15	17	0.41	30	5.4	1.2	1	23	1050	1072	1050	1072	0.94
16	17	0.032	2.4	8.9	0.0	1	23	1082	1104	1082	1104	0.96
17	17	0.00023	0.017	15.7	1.2	1	23	1109	1131	1109	1131	0.97

Sequence Information

Coding Sequence: ATGATGGCTCTAAAGATGTTGTATCGCGGTCCCAGTTCGCGCTTGGAGAATTTGATAGAAAAGATACAGGCCACCAAGGAGATCACAAATAACGATATGTACAGCACACACACCTCTAGCAGCTATTCGCCCAGCATCTCGGACGGCACACTGACGCCCAACTCCCAGCAGCCTCAGCACCCACAGGCAGCTGGAGAGGATGCCTCCATGGAGGAGCAGCACAAGGCGGCAAATGGCGAGGCCAATGAGCAGGATCGACTGCGGGAGAGGGCGAGAGTCAAGCGACCCGGACACTcgcatcaccatcatcatcatcattatcatcatcagcagGCGCTGAAAATTGCCAACAAATTGCGGAAAATCAATAAGGATGCCAAACAGTCGgcaggagctgctgctggcgGCAGCGGAGCAGCCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGAGGCGATGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCATGTGCAGAGCCACGCTGAGCATTTGCCTTTCAAGTGCGAGTACTGCGCCAAGCTGTTCAAGCACAAGAGATCCAGGGATCGCCACAAGAAGCTCCACACCAACGAGCGCAACTACAAGTGTCCACACTGCGAGGCCGCTTTCTCCAGAAGTGATCACCTGAAGATACACATGAAGACGCACGACATACAGAAGCCCTTCCAGTGCTCCATGTGCAATCGTGGCTATAACACGGCCGCCGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCCATCCTGGCGGCTGGGGGGAATCCCAATGCCCTCAACTACAGTCCACGCTCCACTGGGTCCGCCTCCATATCGAGCAATGGCAGTCTGCACAAGCGACGCTATGCCCTGGCCCTCGCCTCCGACAGCAGCCCGAGTCGCCTGGAGTTCCCCAAGCGAGCGAGGGGCGGAGCTGCGCTGACGACCACGCCCACTCCGACGCCAGTGCTAAGGTGCAGTTACTGTCCCAAGGGGGCGACAGGGGAGTTTGGGAGTCTGGAGCAGTTGAATGCACACATGCAGGTGGCCcatgagcagcaacagcagcaggggAGGATCAGTGTGACGCCAGGGGCTGCAGTTGCTCCGAGTGGAGGTGCAGAGGAGTCGCCGGCGAATGGCTTCCAGCTGAGTTGTGAGTACTGCACGATGAGATTCGTGAACATCGCCGGACTGTTCCAGCACATGCGAGCCACACACCTGGACAGATTGAGCAGTCCCAACTCGTACTATGAGCACTTCAATCGCCTGGCCACGGCGGGCACATTTAGTCCCCGCTTGGCACTGGAGTTGCCCAAGCTGAAGCAGGATCTGCTCAGTCCCACGGCCCAGAAGCCGGAGCAGGAGCTGCCCACGGATCTGAGCAGCAACAAGCGACGCACTCCGGGTGGAGGCACTGCATCAGCAGCGGCTGCTCCTCCTGGCGTCTTCTTCTGCAATCAGTGTAATGCCGGTCTGCCGGACTTTGAGAGCTTCCGCAATCATCTGAAGTCCCACATAGCCGAGGGCATGCAGCTCAGCTGCCCCCACTGTGGCCTCAATCTGCCCGAGCAGAGCGACTACGAGCGCCATGTGGTGGCCCACTTCCTCATCACCAGCTCGGAGTACAACTGCAGCGTCGCGAGCTGTGGCAAGTCCTTTGCCAAGGCGgaggaactgcagcagcatctggGGGCGGAGCATGTGCAGACGCTGCTCAAGTGTGGCATCTGCTCGGAGCTCTGTGAGAATCGCATGGCCATGCAGCTCCACCTGGCCTGTGCCCACAGTCAGGAGAGCAAGCTGCTCCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCAATGATACGGACTTCCATGTGCATGTCAAGACACGACATCAGCTGGCGGCACTCGCCAGTGgcgctgctcctgctcccgcGCCCACTGTGGCCAATCCCTTGCAGTGCATGTTCTGTCGCGTCATCTGCGCCTCGGAGCTGGAGATGCACTTCCATCTGGCGGCGCATGCCAGGCAGTTCCGCTGCCCCTCCTGCCCCGAGACGTTCCATGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCATGGTGGCGGCGTCAAGGAGCCCAAGGAGTCGCCCAGCATGGGTAGTCTCTATGTGAACGCCCTGCTCCCTCCCCTggctgccgcagcagcagcagcagctgccgccagcaacaacaacaacaactccagtaacaacaacaacagctccagccacaacaacaacaacaacagtagcctGCACATAGACTACAACGTGGCCTTCAAGGGACTGTTTGGAGCCGGAGCAAGTGCAGCATCAGCTGGAGGCAAGTTCTATAGTCCTCTCCAGGTGGACACGAACAGCCTGAAGTCGCCGCATCCCGCACTCATGTACGGCCTGAGCCAGCGCTATCTGATGGAGATGTATGCCGCCAAGGCCACCTCCCCGGCAGCTGAACCCACAGCTCCTCCGCCGCCGCCCAATCCTCCGCTCAGCTGTGGCATGTGCGAGCGCCAGGATCTGCGCAACGAGGCCGAGCTCCACTCGCATCGCAAGCTGGCGCATAATCTCAAGACGGGAGTCAGCCTGAGGTGCGCCTACTGCTCGGGCAACTTCAAGTCCCGGgcggagctggagcagcacaTGAAGAGCTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTTCCCTCGCCCGCCATTCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGTCAGTCCGGCAAGTGTGCCCACTGTGGCCAGCAGCTGGAGCACGTGGCCGGCTTCCGGGCCCACCTCACCGAGCATGGAGGCGATGGTAGTCTCCCGCTGGCCTGCATCTGTTGCCGGCAGACGCTACACTCGGAGTTCGAGCTGAGTCTGCATGCCAAGTTCCATACCAAATCCTCCAGCTGTGGTGGCAGTCTGCAGGAGCCGGTGTGTGCCCTCTGCCTGGAACCACTCCCAGGTGCTGGGGAGACGGCCAAGCTCTGCGAGAAGTGTTGCCGCAAGCATAATCTGAATGGGAAGCGGAGCAGCAACAAGGAGGCGGCGCCACCAGTCGCTTCCATGGAGCATCGCTGTAATCTCTGCAAGCTCATACTGCCGCACGCCCAGAAGCTGCAGGAGCACCTCGTGGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCTGCGGTCTTCACGGCTCCAGCTGGCCTCCTCACCCACATAGCGGAGCACGGAGCCCGTCCCTACGACTGCAATCTCTGCCCGGAGAAGTTCTACTTTCGCGCCGAATTGGAGCATCATCAGCGTGCCCATGAActgcgtgctgctgctgctcctcctcctccccgtCAACCCAAGCAGGAGACGCACAGCTCCACGGCCAGCTCACCCCTGGCCATGAGTCCCAGCCATGTCAAGCAGGAGCTCTATGAGGCGGATGCAGTGCCCTCGCCCAGTCAGCCGCCGGAGGAAGAGACGCCAGtccaggaggaggaggagtacaTTGAGGTGGAGCAGGTGCCGCAGGAGACACGCTCGGGTGATCTGCTGACCAACACACACGCGGAACgctccagcagcagcgcctAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQQPQHPQAAGEDASMEEQHKAANGEANEQDRLRERARVKRPGHSHHHHHHHYHHQQALKIANKLRKINKDAKQSAGAAAGGSGAATKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGGAALTTTPTPTPVLRCSYCPKGATGEFGSLEQLNAHMQVAHEQQQQQGRISVTPGAAVAPSGGAEESPANGFQLSCEYCTMRFVNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKLKQDLLSPTAQKPEQELPTDLSSNKRRTPGGGTASAAAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLSCPHCGLNLPEQSDYERHVVAHFLITSSEYNCSVASCGKSFAKAEELQQHLGAEHVQTLLKCGICSELCENRMAMQLHLACAHSQESKLLRCSACLELFRNDTDFHVHVKTRHQLAALASGAAPAPAPTVANPLQCMFCRVICASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKEPKESPSMGSLYVNALLPPLAAAAAAAAAASNNNNNSSNNNNSSSHNNNNNSSLHIDYNVAFKGLFGAGASAASAGGKFYSPLQVDTNSLKSPHPALMYGLSQRYLMEMYAAKATSPAAEPTAPPPPPNPPLSCGMCERQDLRNEAELHSHRKLAHNLKTGVSLRCAYCSGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAGFRAHLTEHGGDGSLPLACICCRQTLHSEFELSLHAKFHTKSSSCGGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRSSNKEAAPPVASMEHRCNLCKLILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRAAAAPPPPRQPKQETHSSTASSPLAMSPSHVKQELYEADAVPSPSQPPEEETPVQEEEEYIEVEQVPQETRSGDLLTNTHAERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00832364;
90% Identity: -
80% Identity: -