Laer013143.1
Basic Information
- Insect
- Liodrosophila aerea
- Gene Symbol
- Dis3
- Assembly
- GCA_035045005.1
- Location
- JAWNNL010001092.1:109564-112732[-]
Transcription Factor Domain
- TF Family
- CSD
- Domain
- CSD domain
- PFAM
- PF00313
- TF Group
- Beta-Scaffold Factors
- Description
- In molecular biology, the cold-shock domain (CSD) is a protein domain of about 70 amino acids which has been found in prokaryotic and eukaryotic DNA-binding proteins. When Escherichia coli is exposed to a temperature drop from 37 to 10 degrees Celsius, a 4–5 hour lag phase occurs, after which growth is resumed at a reduced rate.During the lag phase, the expression of around 13 proteins, which contain cold shock domains is increased 2–10 fold. These so-called 'cold shock' proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature, by contrast with heat shock proteins, which help the cell to survive in temperatures greater than the optimum, possibly by condensation of the chromosome and organisation of the prokaryotic nucleoid.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 0.0025 48 4.2 0.0 12 34 274 297 267 305 0.82 2 3 0.16 3.1e+03 -1.6 0.1 34 49 337 353 320 357 0.74 3 3 3.4e-11 6.7e-07 29.4 0.0 3 71 379 446 377 449 0.88
Sequence Information
- Coding Sequence
- ATGCAAACTTTACGCGAATTTACGCGTAAAACAAAGCGCGGTAATATATTAAAGATCGTCCGAGAGCATTATCTCCGAGATGATATTGTATGCGGGTCAGATTTGTGCCAAGTATGTTTCCAAAACGAATACCACTTGACATCGCAGCACACTATAAAAAGTAGCCATTTCAAATTCCCGCATTATATTGTTTTGGACACCAATATTGTGCTGGACCAAATCGATGTGCTCGAGGAGAATGTTTTGTGTAATGTAGTAGTGCTTACTACGGTTTTAAACGAGGTAAAGCACAAGAGTTCGTCCATCTACAAGCGTCTCAACGAAATAATTCATGATCGCACGCGCAGTTTCTACGTCTTTGTTAATGAACATCACAAAGATACCTATGTGGAACGGGAGCCCGATGAGACCGCCAACGATCGGAATGATCGTGCGATTCGTATGGGCGCCAAATGGTACGACTCACATATACAATCCTCGCAAGATTCTAAAACTTTTCAAAGGAGCGGTCGACCAGTCACTCGGGTGGTGCTGATTACTGACGATGTGGGGAACCGTACCAAGGCAGAAGCCGAGGGTATTTTGGTTGCCTCAGCTGCTGAGTACGTTAAATCGCTGGAAGATTTCCCCTTATTGTTAGATAAGTTATCCCAGAAGACATATGAAAGTGAGAAACAGGCAAAGCCCCAATATCCACCTCACTTAAGCATGAAGGAGCTGTTAGAAGGTCTGCGACAAAAAAAAGTGTTACAAGGCTCCTTTCACGCATCAAGGGAAAACTATCTTGAGGGGAATGTTAATGTGGAGAATTACGAAAACGGCATTTTAATCCAAGGACGTGAGGCACTTAATCGTGCCGTAGACGGAGATATTGTGGCTGTAGAGCTGTTACCCGAATGCGATTGGTCAGCGCCCAGTGAAATTGTGCTCGAAGAGAAAAACGTTTATGCTGATGATGTGCCCAGTGAGGACCGAATTGAACAGGAGAAGGAAATGCTAAAGCAAGTACAGACAACACCGGCCACTGAACGGACACCCACCGGACGTATTGTGGGCATTGTGCGTCGCAAGTGGCGACAGTATTGTGGCATTCTTCAGCCCAGTTTGATTGAGGACACCACACGACATATATTTGTGCCTGCAGATCGAAAGATTCCGCGCATACGCATTGAGACACGCCAAGCAGACAAGCTGAAGAATCAACGAATAGTGGTAACCATCGACACCTGGCCAAGAAACTCACGGTATCCGCATGGACACTTTGTACGTTCACTTGGATCTTTGGGTGATATGGCCACCGAGAATGAAGTCATATTACTGGAACATGATGTGCCACATTGCAGATTCTCCGAAGAAGTTCTAAGTTGCTTGCCTAAAATGCCTTGGACCGTTTCAGATGTGGAATTAACCAAACGTGTGGATTTACGAGATCTATATATTTGCTCGGTAGATCCACCAGGTTGTACGGATATCGATGATGCGTTGCATTGCCGCGAGTTGCCTAATGGGCATCTTGAAGTGGGCGTTCACATAGCCGATGTTAGTCACTTCATACGTCCAGGAAATGCTTTGGACAAGGAGGCAGCTGCACGTGGTACAACGGTTTACTTGGTAGGCAAGCGCATTGATATGGTGCCCGAATTGCTTAGCTCCAATCTATGCTCGCTGGTTGGCGGTGCCGAGCGTTATGCCTTTTCCTGTGTATGGGAAATGGATCGGGAGGCGAATATTGTGTCCAAGCGATTTCACAAGAGCGTTATTCAGTCCAAACGTGCCATGACCTATGAGGAGGCCCAGGTTCTTATCGATGATGTCTCACAAACAGGTGAAATTGCGAAATCATTGCGGCATCTCAATCGTCTCGCCAAGGTCTTAAAAAAACGTCGCATGGACAATGGAGCCTTAGTGTTGGCCTCGCCAGAAATACGTTTTCAGGTAGACAGCGAAACACACGAGCCGCTTGAGGTGGAGGCAAAACAGATGCGAGATACCAATTCAATGGTCGAGGAGTTCATGTTGTTAGCCAATATATCGGTTGCTGAACACATTGCAGCTGAGTTTACTGAATGCGCTGTCCTGCGCCGCCATCCAAAACCTCCACCCACGAACTTTGATCCGCTGGTAAAGGCGGCCCGTTACCAAGGGTTTGAAGTAGCCACGGATACTGGATTAGAACTGTCACATTCATTAGATAAATGCGTAAAACCGGATAATCCCTACTTTAATATGATGATACGTATTCTAACCACACGCTGCATGATGCAAGCCGTCTATTTTATCAGTGGTAGCCTACAGAAGGCGGAATTCTTTCATTACGGCTTGGCAGCTCCAATTTATACGCATTTCACTTCCCCTATTCGTCGCTATTCAGACATTATGGTTCATCGCCTGCTGGCAGCCTCGATTGGTGCAGATAGTACCTACGCTCAACTGCTAGAGCGTAAGTCCAATGAAGAGATTTGTAACAATTTGAATTACAGACACAAAATGGCACAATACGCCGGACGCGCATCTGTCGCTCTCAATACACATCTGTTTTTCCGCGGCAAAGAAGAGGATGAAAATGGatatattttgtttgtacGCAAGAATGCACTGCAGGTGCTGATACCCAAGTATGGATTAGAGGGAacattatatttgaaaaacgAAAAGGATTGCAAGGATGGTAAGGAACGTACTAAACCCGACGTAATTTTCACATTCAATGAGGAGGATCACACTCAGAGATGTGGAAATGTGATATTCCATTCCTTCGATCCTGTCACGGTGCGATTAAGCCTGGACTCGAGCAATGTACAGCATGAAAAGTTGGTCTTTAGATTGGTGAAGCCTTATATTAAGGATTTCAGTGTGGAGGCGAAAATACCAATAAATGACAAGGAGACTGCCAATCAGCCACCTGCCAAAAAGAGGAAagataagaaaatataa
- Protein Sequence
- MQTLREFTRKTKRGNILKIVREHYLRDDIVCGSDLCQVCFQNEYHLTSQHTIKSSHFKFPHYIVLDTNIVLDQIDVLEENVLCNVVVLTTVLNEVKHKSSSIYKRLNEIIHDRTRSFYVFVNEHHKDTYVEREPDETANDRNDRAIRMGAKWYDSHIQSSQDSKTFQRSGRPVTRVVLITDDVGNRTKAEAEGILVASAAEYVKSLEDFPLLLDKLSQKTYESEKQAKPQYPPHLSMKELLEGLRQKKVLQGSFHASRENYLEGNVNVENYENGILIQGREALNRAVDGDIVAVELLPECDWSAPSEIVLEEKNVYADDVPSEDRIEQEKEMLKQVQTTPATERTPTGRIVGIVRRKWRQYCGILQPSLIEDTTRHIFVPADRKIPRIRIETRQADKLKNQRIVVTIDTWPRNSRYPHGHFVRSLGSLGDMATENEVILLEHDVPHCRFSEEVLSCLPKMPWTVSDVELTKRVDLRDLYICSVDPPGCTDIDDALHCRELPNGHLEVGVHIADVSHFIRPGNALDKEAAARGTTVYLVGKRIDMVPELLSSNLCSLVGGAERYAFSCVWEMDREANIVSKRFHKSVIQSKRAMTYEEAQVLIDDVSQTGEIAKSLRHLNRLAKVLKKRRMDNGALVLASPEIRFQVDSETHEPLEVEAKQMRDTNSMVEEFMLLANISVAEHIAAEFTECAVLRRHPKPPPTNFDPLVKAARYQGFEVATDTGLELSHSLDKCVKPDNPYFNMMIRILTTRCMMQAVYFISGSLQKAEFFHYGLAAPIYTHFTSPIRRYSDIMVHRLLAASIGADSTYAQLLERKSNEEICNNLNYRHKMAQYAGRASVALNTHLFFRGKEEDENGYILFVRKNALQVLIPKYGLEGTLYLKNEKDCKDGKERTKPDVIFTFNEEDHTQRCGNVIFHSFDPVTVRLSLDSSNVQHEKLVFRLVKPYIKDFSVEAKIPINDKETANQPPAKKRKDKKI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01363704;
- 90% Identity
- iTF_00831911;
- 80% Identity
- -