Basic Information

Insect: Linnaemya vulpina
Gene Symbol: topi
Assembly: GCA_963675445.1
Location: OY776277.1:14729787-14733060[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 8.8 1e+03 1.7 1.1 2 19 183 199 182 201 0.78

2 11 5.6e-05 0.0067 18.0 2.6 1 23 290 312 290 312 0.97

3 11 0.012 1.5 10.7 0.3 2 23 345 366 344 366 0.96

4 11 0.056 6.7 8.6 0.1 2 19 429 446 428 448 0.94

5 11 0.39 46 6.0 1.9 1 22 497 518 497 521 0.90

6 11 4.9 5.8e+02 2.5 0.5 2 22 536 556 535 558 0.81

7 11 7e-07 8.3e-05 24.0 1.9 1 23 578 600 578 600 0.95

8 11 0.0041 0.49 12.2 1.1 1 23 606 631 606 631 0.95

9 11 0.61 73 5.3 1.7 1 23 637 659 637 659 0.88

10 11 8.8e-07 0.0001 23.7 0.3 1 23 665 687 665 687 0.98

11 11 0.028 3.3 9.6 3.3 3 23 695 716 693 716 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	8.8	1e+03	1.7	1.1	2	19	183	199	182	201	0.78
2	11	5.6e-05	0.0067	18.0	2.6	1	23	290	312	290	312	0.97
3	11	0.012	1.5	10.7	0.3	2	23	345	366	344	366	0.96
4	11	0.056	6.7	8.6	0.1	2	19	429	446	428	448	0.94
5	11	0.39	46	6.0	1.9	1	22	497	518	497	521	0.90
6	11	4.9	5.8e+02	2.5	0.5	2	22	536	556	535	558	0.81
7	11	7e-07	8.3e-05	24.0	1.9	1	23	578	600	578	600	0.95
8	11	0.0041	0.49	12.2	1.1	1	23	606	631	606	631	0.95
9	11	0.61	73	5.3	1.7	1	23	637	659	637	659	0.88
10	11	8.8e-07	0.0001	23.7	0.3	1	23	665	687	665	687	0.98
11	11	0.028	3.3	9.6	3.3	3	23	695	716	693	716	0.96

Sequence Information

Coding Sequence: ATGAATTTAAATGAAGATTTGAATACTTCTGATGCTTGGCTCTCAGAGCAATTGTTTGCTCAACTAAAAGACTTAAATGCCGAGTATAAAGACAAAAGTACCCCGGCCGATTTTTTGCTAAGTGAAGTTTTCCAAAGCTGCTCCAATAGCATGCCTTTATTGGACGATGATATTCCATGGCAAGATTTAAAACCAACGCCTTTGGATACTTTCGAATCTGTCAACACTTTGTCTAGCAATTACGATATAAATGAAGTTTTAGATTTAAGCCAGCCCCATACGAAAGAACGTCAGTTGGAATATTCGAAAGCGGAAGGCAATTTATTCGATTTAGTGGAGAACATCCCTTTAATATCGGTCCCAGAAACGTCGAAGGTAAATGAAGTTGCGATTAAGTATGTGCCACCATTATTTGATGCTACAGATGAAGAACTGCAAATACTAAAGTTTCTAGAAAATCAAGAAACTATAGATTCAAAGAATTCAGAATTTGAATCTGTGCCTGTTATACAAGCAGTACCTTTGTCAGCAACACCTAAAGTAATTAAATGCGTTAACTGTAACCTTATGTTCAATAGTGCGGAATTTGATAATCACTTTTGTGATAATAAAGAGGATGAAACAACAAAGGCTCTTACAACGAAAATTATTAGTACTTGCCATCCCATTAAGGAAGAAAGTCACTTGCCTATTGAGCCTGCGTGTATTCGTTTATTAAGAGAAAATCAAATACGCATTAGACGTTTTCtaaaagaagaattaaaatatGACGTGAACAGTAATTGCAACGCAACTGGTTCTATTTCAAATGGATGCTTAAATTCATCCAGTGGTTCTATAAATAGTTCTAAAAAACAGGACGGTCCACATGAATGTACTTTGTGTGAAAGAAAATTCGTCCATGCTTCGGGCTTGTTGCGTCATATGGAAAAACACGCCTTGGACTTAATTCCCACCCCTAATGTTGTatcttacaacaaaaacacatcACTACAAGGTGTCCAGGGCATTAGCGGATTGCGTGTTGTCATTAAATGTACACTATGTGGTCGTATTTTCTTCGATTCAAATGAAGCATTAAATCATTTATATTCACATTTTCCTGATTCAGGAAACGACGAAAAAGAAAGTGATAATTATGCCGAAATTCCTTACGATGCTTACATAGATGATGCCTACAATAATCTAAAATCTGAggctcaaaatttttataatcctATTTCAAGTTACCAGGAAGACAAATCTCCAGTATATCTTAAGATTGTAATATTAAGTTGCATTTTGCAATGCGAATTTTGTGACCTTGTGTTTTCTGAAGTGTCATATTTGTTCGTACATTCTGCATGTCATTTGCCATCGAGAAGATTTGAGTGCTTTGCTTGCGACATTCATGCAAGGACATCGAAGGAAATATGTAATCACTGGCATGCGGAATGTGTTTTTATGCGTGAAAGCTTGAAGGTCTATCAAGCAACTACACAAcgttattttgtttgtaatgtGTGTGAGAACAAATTCCAATCGATGGACTTATTGCATGAACATCGTTATACATCCTACCACTTTTTTCCACGTCTTAACAAAATCACTGGCATATTACAATTACCTTGTGAATACTGCGAAAGTGTTTTTGAAACCGCGCAAGAATGTGTGAATCATTACGAAGAGAAACATTATAAGAAGTATAAACGTGACAAAGATGGAACTACTGTATCAAGTAAGACCAGACAATACTTGTGTGATATATGTGGAAAATCATATACTCAGTCTAGTCATTTATGGCAACATTTAAGATTTCATCAGgGAGTTAAACCATTTGCATGTAAAGAACCAGGGTGTACTCGAAAATTTACAATACGTCCCGACTTAAATGATCACATACGTAAATGCCATACTGGTGAAAGGCCTTACCATTGTCTAGTATGTGGAAAACGATTTCTTACAGGTTCTGTATTTTACCAACATCGTTTGATACACCGTGGTGAACGGCGATATGAATGCGAAGCATGTGGTAAACGCTTCTATCGTGCTGATGCATTGAAGAATCATCAGCGGATTCATACGGGAGAAAAACCCTTCGGATGCCActtttgtactaaaaattttaGACAACGTGGAGATCGTGACAAGCATATTCGAGCACGACATTCTCGCCTGGATGCAAATGCTCGCCTGATGATGCAAATGCAAAAACTACAATTAGAAGCCGCAGCAGCGCAAGTTGGAGGCGATACGCAAAAATTAGCCACCACAACAAATTTTCATGATCACATGGTCGTTGGCAATGAAAATATACCGCCACCAGAGTATGACTCGTCTGAAGCTTCATATGGTAGGAATAACAGCTTCAATGAAATCTTTATGCTTGGCAATCTGgagttttccaaaaatatttttgagtcgATAATGTccgatataattaattaa
Protein Sequence: MNLNEDLNTSDAWLSEQLFAQLKDLNAEYKDKSTPADFLLSEVFQSCSNSMPLLDDDIPWQDLKPTPLDTFESVNTLSSNYDINEVLDLSQPHTKERQLEYSKAEGNLFDLVENIPLISVPETSKVNEVAIKYVPPLFDATDEELQILKFLENQETIDSKNSEFESVPVIQAVPLSATPKVIKCVNCNLMFNSAEFDNHFCDNKEDETTKALTTKIISTCHPIKEESHLPIEPACIRLLRENQIRIRRFLKEELKYDVNSNCNATGSISNGCLNSSSGSINSSKKQDGPHECTLCERKFVHASGLLRHMEKHALDLIPTPNVVSYNKNTSLQGVQGISGLRVVIKCTLCGRIFFDSNEALNHLYSHFPDSGNDEKESDNYAEIPYDAYIDDAYNNLKSEAQNFYNPISSYQEDKSPVYLKIVILSCILQCEFCDLVFSEVSYLFVHSACHLPSRRFECFACDIHARTSKEICNHWHAECVFMRESLKVYQATTQRYFVCNVCENKFQSMDLLHEHRYTSYHFFPRLNKITGILQLPCEYCESVFETAQECVNHYEEKHYKKYKRDKDGTTVSSKTRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFACKEPGCTRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECEACGKRFYRADALKNHQRIHTGEKPFGCHFCTKNFRQRGDRDKHIRARHSRLDANARLMMQMQKLQLEAAAAQVGGDTQKLATTTNFHDHMVVGNENIPPPEYDSSEASYGRNNSFNEIFMLGNLEFSKNIFESIMSDIIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01177337;
90% Identity: iTF_00900079;
80% Identity: -