Basic Information

Insect: Linnaemya tessellans
Gene Symbol: topi
Assembly: GCA_951800035.1
Location: OX637532.1:152953410-152956387[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 9.9 1.8e+03 1.5 0.5 2 19 183 199 182 201 0.77

2 11 5.3e-05 0.0099 18.0 2.6 1 23 288 310 288 310 0.97

3 11 0.16 30 7.1 0.2 2 23 343 364 342 364 0.91

4 11 0.053 9.9 8.6 0.1 2 19 427 444 426 446 0.94

5 11 0.36 67 6.0 1.9 1 22 495 516 495 519 0.90

6 11 4.6 8.6e+02 2.5 0.5 2 22 534 554 533 556 0.81

7 11 6.7e-07 0.00012 24.0 1.9 1 23 576 598 576 598 0.95

8 11 0.0039 0.73 12.2 1.1 1 23 604 629 604 629 0.95

9 11 0.58 1.1e+02 5.3 1.7 1 23 635 657 635 657 0.88

10 11 8.3e-07 0.00015 23.7 0.3 1 23 663 685 663 685 0.98

11 11 0.026 4.8 9.6 3.3 3 23 693 714 691 714 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	9.9	1.8e+03	1.5	0.5	2	19	183	199	182	201	0.77
2	11	5.3e-05	0.0099	18.0	2.6	1	23	288	310	288	310	0.97
3	11	0.16	30	7.1	0.2	2	23	343	364	342	364	0.91
4	11	0.053	9.9	8.6	0.1	2	19	427	444	426	446	0.94
5	11	0.36	67	6.0	1.9	1	22	495	516	495	519	0.90
6	11	4.6	8.6e+02	2.5	0.5	2	22	534	554	533	556	0.81
7	11	6.7e-07	0.00012	24.0	1.9	1	23	576	598	576	598	0.95
8	11	0.0039	0.73	12.2	1.1	1	23	604	629	604	629	0.95
9	11	0.58	1.1e+02	5.3	1.7	1	23	635	657	635	657	0.88
10	11	8.3e-07	0.00015	23.7	0.3	1	23	663	685	663	685	0.98
11	11	0.026	4.8	9.6	3.3	3	23	693	714	691	714	0.96

Sequence Information

Coding Sequence: ATGAATTTAAATGAAGATTTAAATACATCTGATGCTTGGCTTTCGGAGCAACTATTTGCCCAGCTCAAAGATTTGAATGCTGAGTATAAAGACAAAAATACACCTACAGATTTTTTGTTAAGTGAAGTTTTCCAAAACTGCTCGAACAGCATGCCTTTATTGGATGATGATATTCCTTGGCAAGATCTAAAACCAACGCCTTTGGACACGTTCGAGTCTGTCAACACTTTGTCTACCAATTACGATATAAATGAGGTTTTGGATTTAAGCCAGCCCCACACGAAAGAACGTCAGTTGGAATCGACAAATGCTGAAGAGACCTTATTCGATTTAGTGGAAAACATTCCTTTGATATCGGTCCCAGAATCTTCGAATGTAAATGAAGTTGCGATTAAATTTGTGCCGCCTTTATTTGATGCTACCGACGAAGAACTGCAAATACTAAAATTTCTAGAAAACCAAGCGACTCCAGATTCAAAAaATGCAGAATTTGAATCTGTGCCGGTTACACAATCATTGCCTTTGTCAGCAACATCCAACGTAATTAAATGTGTTAACTGTAACCTTATGTTTAATAGTGGCGAATTTGATGGTCATATTTGTGATAATAAGGATCAAATAAAGGGTATCACAACGAAAATTGTCAGCACTTGCAATCCCATTAAAGAAGAAAGTCACTTGCCTGTTGAGCCTGCATGTATACGTTTATTGAGAGAAAATCAAATCCGCATTAGACGGTTTCTCAAAGAAGAGTTAAAGTATGACGTGAACAGTAATTGCAATGCAACTGCTTCTATTTCAAATGGATCTTTAAATTCATCCAGTAGTTCTATAAATGGTACTAAAAAACAGGACGGCCCGCATGAATGCACTTTATGTGAAAGAAAATTCGTCCACGCTTCGGGTTTGTTACGTCATATGGAAAAACACGCCTTGGATCTAATTCCCACTCCTAATGTAGTATCTTATAACAAGAACGCATCCTTACAAGGTGTCCAGGGGATTACCGGATTGCGTGTTGTCATTAAATGTACTCTTTGTGGTCGTATTTTCTTTGCTTCAAATGAAGCATTAAATCATTTATATTCACATTTTCCTGATTCAGTAAAcgaagaaaaagaaattgataATTATGCGGAAATTCCTTACGATGTCTATATAGATGATGCTTACAATAACCTAAAATCTGaggctcaaaatttttataatcctATTTCAAGCTACCAGGAGGACAAGTCTCCAATGTATCTTAAGATAGTAATACTAAGTTGCATTTTACAATGTGAATTTTGTGATCTTGTATTTTCTGAAGTGTCATATTTGTTTGTACACTCTGCATGTCATTTACCATCTAGAAGATTTGAGTGCTTTGCTTGCGACATTCATGCAAGAACATCAAAGGAAATTTGTAACCATTGGCATGCGGAATGTGTTTTTATGCGTGAAAGCTTGAAGGTCCATCAAGCAACTACGCAACGTTATTTTGTTTGTAATGTGTGTGAGAACAAATTTCAATCAATGGACTTATTGCATGAACATCGTTACACGTCGTACCATTTTTTTCCACGCCTTAACAAAATCACTGGCGTTTTACAATTACCCTGTGAATATTGCGAAAGTGTTTTTGAAACAGCTCAAGAATGCGTGAACCATTACGAAGAGAAAcattataagaaatataaacGCGATAAAGATGGAACTACTGTGTCAAGTAAAACCAGACAATACTTGTGTGATATATGTGGAAAATCATATACTCAATCCAGTCATTTATGGCAACATTTAAGATTTCATCAAGgAGTTAAGCCATTTGCATGCAAGGAACCAGGTTGTACCCGAAAATTCACAATTCGTCCTGACTTAAATGATCACATACGTAAATGCCATACTGGTGAAAGGCCTTACCATTGCCTAGTATGTGGAAAACGATTTCTCACAGGTTCGGTTTTTTACCAACATCGTCTCATACATCGTGGCGAACGACGATATGAATGCGAAGCATGTGGTAAACGATTCTATCGTGCTGATGCATTAAAGAATCATCAACGGATTCATACTGGAGAAAAACCCTTTGGATGTCACTTTTGTACTAAAAACTTTAGACAACGTGGAGATCGTGACAAGCATATACGAGCACGACATTCTCATCTGGATGCGAATGCACGACTTATGATGCAAATGCAAAAACTACAATTAGAAGCCGCTGCGGCACAGGTTGGAAGCGACCCGCAAAAACTAGCTACTACAACAAATTTTCATGATTACATGACCGTTGGTAATGAAAATATACCTCCACCAGAGTATGACTCTTCCGAAGTTTCATATGGtaagaataataatttcaatgatATTTTTATGCTTGGGAATTtggatttttccaaaaatatttttgagtccATAATGTCGGATATGACTAATTAA
Protein Sequence: MNLNEDLNTSDAWLSEQLFAQLKDLNAEYKDKNTPTDFLLSEVFQNCSNSMPLLDDDIPWQDLKPTPLDTFESVNTLSTNYDINEVLDLSQPHTKERQLESTNAEETLFDLVENIPLISVPESSNVNEVAIKFVPPLFDATDEELQILKFLENQATPDSKNAEFESVPVTQSLPLSATSNVIKCVNCNLMFNSGEFDGHICDNKDQIKGITTKIVSTCNPIKEESHLPVEPACIRLLRENQIRIRRFLKEELKYDVNSNCNATASISNGSLNSSSSSINGTKKQDGPHECTLCERKFVHASGLLRHMEKHALDLIPTPNVVSYNKNASLQGVQGITGLRVVIKCTLCGRIFFASNEALNHLYSHFPDSVNEEKEIDNYAEIPYDVYIDDAYNNLKSEAQNFYNPISSYQEDKSPMYLKIVILSCILQCEFCDLVFSEVSYLFVHSACHLPSRRFECFACDIHARTSKEICNHWHAECVFMRESLKVHQATTQRYFVCNVCENKFQSMDLLHEHRYTSYHFFPRLNKITGVLQLPCEYCESVFETAQECVNHYEEKHYKKYKRDKDGTTVSSKTRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFACKEPGCTRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECEACGKRFYRADALKNHQRIHTGEKPFGCHFCTKNFRQRGDRDKHIRARHSHLDANARLMMQMQKLQLEAAAAQVGSDPQKLATTTNFHDYMTVGNENIPPPEYDSSEVSYGKNNNFNDIFMLGNLDFSKNIFESIMSDMTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01177337;
90% Identity: iTF_00900989;
80% Identity: -