Lhum006557.1
Basic Information
- Insect
- Linepithema humile
- Gene Symbol
- znf423
- Assembly
- GCA_000217595.1
- Location
- NW:1645883-1719445[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 2.4e-05 0.0015 18.2 1.5 1 23 144 166 144 166 0.98 2 22 0.4 25 4.9 3.9 1 23 172 194 172 194 0.97 3 22 8.7e-07 5.4e-05 22.7 4.3 1 23 200 222 200 222 0.99 4 22 0.00019 0.012 15.4 0.2 1 23 228 250 228 250 0.99 5 22 0.00078 0.049 13.4 2.3 1 23 415 438 415 438 0.97 6 22 0.18 11 6.0 0.1 2 23 449 471 448 471 0.88 7 22 0.17 11 6.1 0.1 3 23 537 557 536 557 0.97 8 22 0.00087 0.055 13.3 0.2 1 23 572 594 572 594 0.97 9 22 0.0015 0.091 12.6 0.7 1 23 603 626 603 626 0.94 10 22 3.1 2e+02 2.1 0.2 1 23 631 654 631 654 0.91 11 22 9.5 6e+02 0.6 0.1 8 23 687 703 686 703 0.92 12 22 0.99 62 3.7 2.1 2 23 734 755 734 755 0.96 13 22 0.015 0.94 9.4 0.1 1 23 760 783 760 784 0.93 14 22 2.8 1.7e+02 2.3 0.1 2 23 849 872 848 872 0.81 15 22 4.2e-05 0.0026 17.4 1.0 2 23 888 910 887 910 0.96 16 22 0.074 4.6 7.2 1.0 1 23 919 942 919 942 0.92 17 22 3.5 2.2e+02 1.9 0.2 3 23 951 971 949 971 0.95 18 22 0.0017 0.11 12.3 0.1 2 23 1137 1159 1136 1159 0.96 19 22 0.062 3.9 7.5 0.3 1 23 1174 1197 1174 1197 0.96 20 22 3.6 2.3e+02 1.9 0.2 2 23 1210 1231 1209 1231 0.92 21 22 0.011 0.66 9.9 0.1 2 23 1240 1262 1239 1262 0.94 22 22 0.016 1 9.3 3.5 1 23 1269 1292 1269 1292 0.97
Sequence Information
- Coding Sequence
- ATGTCCAGGAGGAAACAGGCGAAACCTCGATCTCTCAAGCGGGACGAAGAGTGGGACGACGGCAACGAGCAGAATGTCCTGGAGGCGGCCGAACAGGATAACGGAACGACGACGATTAAGCAGGACGatgaagaagaggaggaagaggaggagttGCAGCGGGCGTTCAGCCGTCAGTCAGAagACTATCTGCAAGATGGCAGACCAACTTCCGTCCAAGGCCCTGATCTGGAAAATCAGAACAGCCTCGACAGCGAGGCTTTAGGAACCGGAAGTTCCTCGTGGCACAGCGAGGATGGCGGTCTCAACTCGCGTCGCGGTGAGACACCGTCTTCCTGCGCAACGCCGACGTCAACCAGCTTTCCATCGGAACCCGAGGTTGACACCGACGTCGGTGTCAATGCCGATGGTAACAACCCCGCCGCTCCCTATCCCTGCCAGTTCTGCGAAAGGACGTTTCCGCGGCTTAGCTATCTGAAGAAACACGAACAGAGCCACGGGGATCAGATGCCGTATCGATGCAGTTGGTGCGCTAGATTGTTCAAGCACAAGCGTAGTCGCGATCGTCACGTAAAGCTGCACACCGGAGACAGGCGATATCGCTGCACGCATTGTGAGGCTGCCTTCTCCAGGAGCGATCACCTGAAAATTCATATGAAGACGCACGACACCCAGAAGCCTTACCAATGCACAGCTTGCTCGAGAGGCTACAACACAGCCGCAGCCCTGACGTCGCACATGCAATCGCATAAAAAGCATCACCAGTCATCTTCCCAGTCGGCCGGCGGCAAGCTTCAAGATGTTGACTACGGCAGACGAAGCGTTTCCTCGCATAGCACATCGTCGCCACCGgtgccgtcgtcgccgtcgccgtcccTGAATCTCAGTCTGAACTCGAAGAACGTCCTGAAGACGTCGCAGGGTACCGGCAGCGCTTCCACCACGCCCGTCCTCAGCTCACCTCTGAAGCTTACCTGCATGTACTGCACTCGGGACTCGTTCAACTGCATGCAGCAACTCCAGATGCACGTGCACACGATGCATCAGGCGATCCTGAGCGGCGCGGAGGGTCTGGCGCGACCCCCATCGCCGAGCAGAACGTTGAACGAGCAACAGGCGGCTGTCTGCCCACGCGACAAGCTGCTGGACCGTCAGAACGGCACGAAGGAGTCGCGGCCGGACCGGAAGTACTCCGAGGATCGAAACGGGAGACCCAGCGAACGGGACCACTACGAGAATGCGTTCACCTGCAATCAGTGCACCATGAAGTTCTCCACGCTAGCCTGCCTGCGCGATCATCTGCTCTCGATACACCGCCTCGACGCTTTCGGCGCGGCGATGATGATGTGCCCGCTGTGCGGCATTCCGTGCTCCTCGGCGCCCTCCTACGCCGAGCATTACGTTCTTCAGCACTGCGAGAATCGCCGACCGGCGCCGACGATAGATTACGGGGGGGAGGCGAAGTTGAACGGCGTTTACGACGGCACGGTGAGGGATTCCAGAGCGCCGCGGAGCAGAGACGCGCCGGAAGCGACCGATCTCACGAACAAGCATTCGACCAGGCCGACCGCGGACGTCGCTGGCGGCTACACCGCCAGTACGCTGCTGTGCGGCCAGTGCGGCGCCGCGCTCAAGGACTTCGAGTCCTTCCGCGAACATCTGGCGCGACATCTACAGGCCGATCATCGCGGACAGGAAGCGCCCAGCAGGCAGCATCCGTGTCCCAAGTGCGATGCCTTCTTCCCGGATCGCGAGGATATGTTGGCTCACCTGACCAAGCATTATCTAGGCCAGATTAGCAAAGAGTACACGTGTAACGCGTGCAAGAAGCTGTACCCGCATCCGGAGCAGCTTCAGAAGCACCTGCTGGACGTGCACGCCCATCATCTCTATCGTTGCGCCCTGTGCCGGGACACTTTCGACTCCAGGGTGGCGATACAGGTGCACTTTGCGGTGAAGCACAGCCAGGAATGCCGGGTCTATCGATGCAGCGCGTGCACCTTGTCCAACAATGAAAACTCGCCGCCGGTCTCGAATCCGGCATCCGGCGACGGCAGGACCTCCTTCAGAAGCGAAGCCGAGATGGCAGCCCACGTGCGCAATGTTCACGCACCTCCTCCCGTCGCTTCTCTAATGAACAGCAGCCCAGTGGCAGCCACGAGGAGTCCCGCCTCGACGCCTGGCGGCGGCATCGCGGCGCGCTGCGTCTTCTGCGGCTTCTGCTGCGGCTCGGAGCTCGAGCTGCAGCTTCATCTAGCGAGCCACTCGACCAATCTCTACAGGTGTCCTATCTGCAGAGAAGGCTTCCCGGTAGAGTTCCTGCTGGACCGACACGTCGCTCAGGCTCATCACGCGGTCCAGGATCATCAAGCGCCGTCCATCAGGAGCAACTCGAGGGAGAACGGCCGTCTTCATCGACCGATCAGAAATCAAGAAGAAACGAAATCTCTGAAGAGAGGTCGCTCGCCAGCATCGAGCAACAATAATTCCCTGAATCAGCGCGATAACAACAACAAGCGTCCAAGCTATGGCACTTCTGGCCAGCAGTGCGAGCTGTGCGAGCGCGGCGAATTCGCGAACGAGGCGGAATTACAGGCGCACAAAAAACTCGCTCATACGTCCTCCAAGCTGTCCAGCAAGAGTTTATCCGCTTTGAGTATGACGTGTGCTTATTGCGGCGAGGTATGTCGTTCGCGAAGCGAGCTAGAGTCGCATACAAGGATCCAGCACGCATCTAACGAACCCGGCGGACGTCACAAGTGCAACGTCTGCGACGAGGTGTGCCCATCCGGCGTGAGCCTGGCCGAGCATAAGCTTCAGAAGCACTGCAAGATCCAGCTGAGTGACATGTGTGTGGTGTGTCGCGGCTCTCTAACCTCGGAGAACCAGTTCTTGGACCACGTGCAGAGACATAGTCTGGAGAGCGTGGATCCGCAACAGCGACTGGACAATTCGCTGCCGCACCTGCCAGCCCCGTGCGTCGTCTGCCGGCAGACGCTGATCAGCGATTTGGAGTGTCGTCTGCACGCGCGGCATCATCTACGAACGTCTTCGGGATCACGTAGCGCCGGTTCTAGCCCAACTAGTCCCGGCGGCAAAAGTCAGAGTCAGAGTCAGAGTTGCTGTCTCTGCCTGCGGGACTTCGCAGCGGAAGACTTTGTCAGCTTGCCTCCTAATCCTGCCAGCACAAGCGGACAGTCGGTCAAAGTGTGCAAATCCTGCTACGTACGACATTCTCAAGGTTTGCCTATCCTGAATTCGTCGGCTTATGAGCAACGAGCTAAATACGAGGCAACCTGGCTGATGAACAAAGATGGTCAATGGGACGCTTCCAAGGACAAGTGGGAGCACGAGAGAGGACTCAAGGTGGACGATCGAATCAGGAATGAAGGAAATGCAGAGAAGAAACGCTGCGAAGAGTGCGGTGTGAAGTTTGAAGATCCTGAAGAAGCGGAAAAGCACAGAATCACTGAACACGAGAAGGctggtggtggcggcggcggcggcggctcgAATACCTATACGTGTATACAATGCCAGATGTCGTTCCCAACTGAAGCTAAGATTCAACAACATGTAAGGAAAGAGCATCTAGATGCATCTGGAAAAGCCTCCTTAGAGGCTTTACGGTGTCACTTGTGCTTATTCGAAGCAGGTAGCCCTATGCAGCTGCAAATCCACTTGATAGAGCACACTTTCGCCGGATGCGCTGCTCTTAGTTGTTACATCTGCCAGTCGCTCTTTACCACCCCTGTTGGCCTTCAGAATCATATGCTGCAAGAGCACGGCCTAGGCGCACGACCATACGATTGTTCCAAATGCACGCTCAAGTTCTTCTTCAGGGCAGAACTGGATCACCACATGCTAACTTTTCATCGTCCGGGGGAGGAGGTTCATTCTTCACTGACCGAAAACACACGTGAAACAAAGAATCACGAACTCGAAGAGCGCAACTGCGATGGCGGTGTGATAGTAAAGGAGGAAGTGATACAAGGCGgtgaggaagaagaagaggaagtgAATGTGGATGATCAGGTGGGGCAGGAGGAACAAGAGGAAGCTCGACCGGAGGAGCAGAAGCTGAAGACGGAAGTAGAAAACGAAACGGCATCCGACAAGATGCAATCGTGA
- Protein Sequence
- MSRRKQAKPRSLKRDEEWDDGNEQNVLEAAEQDNGTTTIKQDDEEEEEEEELQRAFSRQSEDYLQDGRPTSVQGPDLENQNSLDSEALGTGSSSWHSEDGGLNSRRGETPSSCATPTSTSFPSEPEVDTDVGVNADGNNPAAPYPCQFCERTFPRLSYLKKHEQSHGDQMPYRCSWCARLFKHKRSRDRHVKLHTGDRRYRCTHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSSSQSAGGKLQDVDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNSKNVLKTSQGTGSASTTPVLSSPLKLTCMYCTRDSFNCMQQLQMHVHTMHQAILSGAEGLARPPSPSRTLNEQQAAVCPRDKLLDRQNGTKESRPDRKYSEDRNGRPSERDHYENAFTCNQCTMKFSTLACLRDHLLSIHRLDAFGAAMMMCPLCGIPCSSAPSYAEHYVLQHCENRRPAPTIDYGGEAKLNGVYDGTVRDSRAPRSRDAPEATDLTNKHSTRPTADVAGGYTASTLLCGQCGAALKDFESFREHLARHLQADHRGQEAPSRQHPCPKCDAFFPDREDMLAHLTKHYLGQISKEYTCNACKKLYPHPEQLQKHLLDVHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRVYRCSACTLSNNENSPPVSNPASGDGRTSFRSEAEMAAHVRNVHAPPPVASLMNSSPVAATRSPASTPGGGIAARCVFCGFCCGSELELQLHLASHSTNLYRCPICREGFPVEFLLDRHVAQAHHAVQDHQAPSIRSNSRENGRLHRPIRNQEETKSLKRGRSPASSNNNSLNQRDNNNKRPSYGTSGQQCELCERGEFANEAELQAHKKLAHTSSKLSSKSLSALSMTCAYCGEVCRSRSELESHTRIQHASNEPGGRHKCNVCDEVCPSGVSLAEHKLQKHCKIQLSDMCVVCRGSLTSENQFLDHVQRHSLESVDPQQRLDNSLPHLPAPCVVCRQTLISDLECRLHARHHLRTSSGSRSAGSSPTSPGGKSQSQSQSCCLCLRDFAAEDFVSLPPNPASTSGQSVKVCKSCYVRHSQGLPILNSSAYEQRAKYEATWLMNKDGQWDASKDKWEHERGLKVDDRIRNEGNAEKKRCEECGVKFEDPEEAEKHRITEHEKAGGGGGGGGSNTYTCIQCQMSFPTEAKIQQHVRKEHLDASGKASLEALRCHLCLFEAGSPMQLQIHLIEHTFAGCAALSCYICQSLFTTPVGLQNHMLQEHGLGARPYDCSKCTLKFFFRAELDHHMLTFHRPGEEVHSSLTENTRETKNHELEERNCDGGVIVKEEVIQGGEEEEEEVNVDDQVGQEEQEEARPEEQKLKTEVENETASDKMQS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01406753;
- 90% Identity
- -
- 80% Identity
- -