Basic Information

Insect: Limnephilus auricula
Gene Symbol: Hr39
Assembly: GCA_951813805.1
Location: OX638413.1:3754501-3788091[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.29 4.1e+03 -2.5 0.2 59 113 95 124 44 215 0.48

2 4 0.24 3.5e+03 -2.3 7.6 30 159 256 338 189 384 0.49

3 4 5.4e-10 7.6e-06 26.2 1.8 1 131 494 614 494 630 0.61

4 4 3.7e-69 5.3e-65 221.1 0.0 205 408 640 841 634 841 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.29	4.1e+03	-2.5	0.2	59	113	95	124	44	215	0.48
2	4	0.24	3.5e+03	-2.3	7.6	30	159	256	338	189	384	0.49
3	4	5.4e-10	7.6e-06	26.2	1.8	1	131	494	614	494	630	0.61
4	4	3.7e-69	5.3e-65	221.1	0.0	205	408	640	841	634	841	0.96

Sequence Information

Coding Sequence: ATGGCTAGCACCATCACCGGATCGCCGCTGAGCGAGATCGGAGTTAAAGTGGAAAATTGTAGCCGAAACGTATCTGTTACTCCTATCAACATGTCAGATTCGCAGGTGGCCAATGGCCAGTTCTCATACAGCTCCCAGGGTGTGAGGATTAGCGTTCCTTCGCAGGAGCGCCAGCCGTCGGGGCTGGACGAAGACTCCAACGATGCCGAGGTCTCCAGCATTGACTTCTCGCAGCATCACTACCAGGTGAACATGAGAACGAAGAAGAAGCGTCCGTCTTCCAGTTCTATGACCCCCTCCAACGAGATACTGAGGGAGCCGTCGCCCCTGGACAGCCGGGAGCGCCCCATGTCGTGGGAGGGGGAACTTTCCGACTCGGAGATGATGGTGGACTCCTCTCAGGAGCGGCAGCACGACACCGGATACTCTCAGAGcCCCCGTGACAGCGGGATCTGCGAGCGGGAGCAGGGCACCCTGGGGCCCTCCAGCCGCCAGAGCTCCATCTCCTTCCAGAGTCTGCGGGACCAGGACGCCCTCAACCTCAAGTTCCACCGGCCCACCCTGCAGCATCACCAGCGGAGCCACAGCATGAATAGGATGTCGGTTCTGGCCAGCGACCTGACGGACGTGCGCAGCCCCCCCTCCCCCCTGCCGCCCCCCAAGCCGGCGCCGCCCCCTCCCGCCTCCGGTGACCAGGGCGACGCGCGGCCCGAGCAGAGCATCAAGAACATGCCCGTCAACATCATCCCGCAGTCCCTGTCCAACAAGATGGCGGCCGATGCGCAGGCGTACGCGTGCAAGCGCGAACAACACCAGCAGCTCACTGTCACACCTGATATAAAGCCGGAGCTGCCCCTCCTGGTGGACAAGCTGTTGGGCGGGTACTCTCTGCACAGCACCCCCAGCAACTCTCCGCTGCTGAACCGGCACCACAAGATCGTGTCCAACTCCAGTACGGATTCTGCCGTTCACTCTGCTTACACTCACAGTGTGTACAGTAGTCCGTCTGCTAGTCCGGGAGCCACACGGCACGCCCCCTACACCCCCTCCCTCTCCAGGAACAACAGCGACGCCTCCCACTCCTCCTGCTACTCCTACAGCTCCGAGTTCAGCCCCACGCATTCTCCCGTGCAGGGTCGCCACCTGCCTTCCCATGCGGCGCTTTTCCGCTCGGAACACAGCGGGGTGGTGAGGCAAGGCGGTGTGGAGGGACCCGACAGTGGCAGCCCTGACCACCAGGGCGTCAGCAGGCAGCAACTCATCAACAGCCCGTGCCCCATCTGCGGCGACAAGATCTCGGGATTCCACTATGGCATCTTCTCGTGCGAATCGTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACCGCAAGAACTACGTTTGCTTGCGCGGCGCCAACTGCCCCGTGACCGTGGCCACGCGCAAGAAGTGCCCCGCGTGCCGCTTCGACAAGTGCCTGCACTGCGGCATGAAACTCGAagCTATCCGAGAAGACCGTACGCGAGGTGGGCGCTCCACCTACCAGTGCTCCTACAGTCTCAGTGGGGCCGCCTCCACCAGCTCGCTGCTGGGCGCGGGCCTGCCTTCGGGGCCCCTGCGTCACGCTACCAGCCTCACTTCCGTAAACGGACCGTCTAACCACCTGTCATACCGATCGCACCACGATCTTCACTCGGCCTCCATGGGCAGCCACATGCAGAAGTCGGAGCAGGGCCAGGGTCACATGATGCACCATGACCCCATGGGGGTTCCGCAGCTGCTGCAGGAAATAATGGACGTGGAGCACCTGTGGCAGTACAATGAGAGCGAACTAAGCCGCATCAACAAGGGGCAGCCCCCCTCGGGCTCCGCCCCTCCCCCCTCCACCCCACCCTCGCTGGACAACCCCCTGCTGCGGGGCGCTCGCCTGCCCCCCGACAGCAGCCCCGACTTCCTGGCCAACCTGTGCAACATCGCCGACCACCGCCTCTACAAGATAGTCAAGTGGTGCAAGAGTCTGCCGCTCTTCAAGAACATCTCCATCGATGACCAGATCTGCCTCCTCATCAACAGCTGGTGCGAGCTGCTGATGCTGTCCTGCTGCTACCGGGGGGTCAGCACTCCCGGAGAGGTCAGGGTCAGCGGGGGCAGTCGGGGCATCACGCTGCAGCAGAGTAGCAAGATGGGACTGACACCGTGCATCGAGCGCATGCTGCACTTCACGGACCACCTGCGCCGGCTGAAGGTGGACCGCTACGAGTACGTGGCCATGAAGGTCATAGTCCTGCTCACTTCAGACACGTCTGAGTTGCGTGAGCCGGAGAAGGTGCGAGCGTCGCAGGAGAAGGCTCTGCAGGCGCTACAGGCGTACACGCTGGCACACTATCCCGATACCCCTGCCAAATTCGGGGAACTGCTGCTCAGGATACCGGAACTGCAGAGAACTTGCCAGGTCGGCAAAGAAATGCTCAACCCCTCAAACAAATCCAAGGACGGAGAAGCGCCGAGCTTCAACCTCCTCATGGAGCTGCTGCGGGGTGACCACTGA
Protein Sequence: MASTITGSPLSEIGVKVENCSRNVSVTPINMSDSQVANGQFSYSSQGVRISVPSQERQPSGLDEDSNDAEVSSIDFSQHHYQVNMRTKKKRPSSSSMTPSNEILREPSPLDSRERPMSWEGELSDSEMMVDSSQERQHDTGYSQSPRDSGICEREQGTLGPSSRQSSISFQSLRDQDALNLKFHRPTLQHHQRSHSMNRMSVLASDLTDVRSPPSPLPPPKPAPPPPASGDQGDARPEQSIKNMPVNIIPQSLSNKMAADAQAYACKREQHQQLTVTPDIKPELPLLVDKLLGGYSLHSTPSNSPLLNRHHKIVSNSSTDSAVHSAYTHSVYSSPSASPGATRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHLPSHAALFRSEHSGVVRQGGVEGPDSGSPDHQGVSRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGANCPVTVATRKKCPACRFDKCLHCGMKLEAIREDRTRGGRSTYQCSYSLSGAASTSSLLGAGLPSGPLRHATSLTSVNGPSNHLSYRSHHDLHSASMGSHMQKSEQGQGHMMHHDPMGVPQLLQEIMDVEHLWQYNESELSRINKGQPPSGSAPPPSTPPSLDNPLLRGARLPPDSSPDFLANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLMLSCCYRGVSTPGEVRVSGGSRGITLQQSSKMGLTPCIERMLHFTDHLRRLKVDRYEYVAMKVIVLLTSDTSELREPEKVRASQEKALQALQAYTLAHYPDTPAKFGELLLRIPELQRTCQVGKEMLNPSNKSKDGEAPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00897899; iTF_01086362; iTF_01086344; iTF_00675197; iTF_00675181;
90% Identity: iTF_00897899; iTF_00675197; iTF_00675181;
80% Identity: iTF_00897899;