Lnig004181.1
Basic Information
- Insect
- Leuctra nigra
- Gene Symbol
- MBD4
- Assembly
- GCA_934046545.1
- Location
- CAKOHC010000311.1:262786-268443[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 8.2e-15 5.7e-11 43.1 0.0 9 70 108 167 105 171 0.94
Sequence Information
- Coding Sequence
- ATGACAGAGGACACGAAACACAAAGTAGCAAAGAGTGAAGATAAAATTACGCACCATCAACTAGGTGAGAGAGATAAAAGTTCCCCACAAAAGAAGGTGGTTAAAACGAACACGTCAAAAAGTAGTGATGCTGCGAAGAAGCAGAAGAGAAGCAAGGAGAGCAGTGAAAGTGCAAAGTCAACAGGTGAAGATTCTTCGAAAATCGTCAAGCAGAAGAGTGAGGTGAAGTCCACTGTGAAGTTAAATCCATCCTCGGGtctgaagaaaaagaagaagctGAAAACTCATAGCGGTGGCTCCCAGCAGCCTCTGCTTGTGGACGATCGACTTCCGGAGGGCTGGAAGCGCCTCGTTGTTCAGCGCCAAGGAGGAGCATCTATCGGGAAATATGACGTCTACATTATTGGACCAAATATGCACAAGTTTCGCTCTCGCAAGGAGCTTGGGACGTACATTGAGACGGAAGGAATAGACCTTCAGGCTCAAAGCTTCGACTTCTCAGTATTCGGGAAAGAGTTAGCTAATGCTGATGATTCCGCTCCCCAAAAGTCCACACATAAGCCCACTAAAAAGCCCAAGCCTGCGGATGCGATCATGGAGGATGAAAAGCCTGTGAAGCGGAGCTATAAGCAGCGTGTGAAGAAGGGGAAACTGACATACGAACAAGTTAGAGAAATGGTCACCAGCGACTTCCTGTCGACAAGGATGTCCAACCGGTCGCTAAAGTGGACTCCCCCGAGATCGCCGTACAACTTGATCCAGGAGAATCTGTTTCACAACCCCTGGCAGCTGTTGGTCGCCACCATTCTGCTCAACAAGTCTTTGGGCTCAACGGCTACTCCCATCATCTACGGAATCTTCCGCCGCTGGCCGACGCCAGAGGCGATGGGTTACGCAGATGAGAAGGAGTTGGCGGTCACCATACGTCCACTCGGGCTTCACAAAAAGAGGGCGAGTTCCATAAAGAAATTCTCAGAGGAGTTCCTGACACGCGAGTGGACGTATCCCAACGAGTTGCACGGCATCGGGAAGTACGGGAACGACAGCTATCGGATGTTCTGCGTCAACGAGTGGCGCTACGTCCAGCCCAGCGACGTCATGCTCACCATGTACAAGAACTGGCTGCAGAACAACTGGGCGGCGCTCTGCAACAACACCAACAACTGCCTCGGGTTGAACAAGTCGGAAGACGACTCTCCCCAGGACAGTGATGCGGAAGTGATTCACAGAAGTAGAACAGATGTTTCTTGA
- Protein Sequence
- MTEDTKHKVAKSEDKITHHQLGERDKSSPQKKVVKTNTSKSSDAAKKQKRSKESSESAKSTGEDSSKIVKQKSEVKSTVKLNPSSGLKKKKKLKTHSGGSQQPLLVDDRLPEGWKRLVVQRQGGASIGKYDVYIIGPNMHKFRSRKELGTYIETEGIDLQAQSFDFSVFGKELANADDSAPQKSTHKPTKKPKPADAIMEDEKPVKRSYKQRVKKGKLTYEQVREMVTSDFLSTRMSNRSLKWTPPRSPYNLIQENLFHNPWQLLVATILLNKSLGSTATPIIYGIFRRWPTPEAMGYADEKELAVTIRPLGLHKKRASSIKKFSEEFLTREWTYPNELHGIGKYGNDSYRMFCVNEWRYVQPSDVMLTMYKNWLQNNWAALCNNTNNCLGLNKSEDDSPQDSDAEVIHRSRTDVS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -