Basic Information

Gene Symbol
Aef1
Assembly
GCA_018903435.1
Location
JAEIFJ010003025.1:3399838-3400629[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0012 8.9 6.9 0.1 21 49 21 49 9 52 0.83
2 4 2.2e-05 0.17 12.4 0.0 21 52 49 80 45 81 0.88
3 4 0.0023 18 5.9 0.1 21 51 77 107 75 108 0.87
4 4 7.2e-05 0.55 10.7 0.1 21 47 105 131 101 138 0.88

Sequence Information

Coding Sequence
ATGCACCTTGCGTCGTCTGGAGGTAGTGGTGGCGGCGGCAGTAGAGATCCTAGTGGTAATCCTGAAAAACCATTTCAGTGCAATGTCTGCGATCGAAGGTTTCGACAGCTAAGCACGCTTACAAATCATGTTAAAATACATACAGGCGAGAAGCCTTACAAATGCAACGTTTGTGATAAAACCTTCCGTCAATCGTCAACGCTGACGAATCACATGAAGATACATACCGGTGAAAAACCGTACAATTGCACCTATTGCCCTAAGCATTTCCGTCAGTTAAGCACGTTAGCCAATCATCTCAAGATACATACGGGTGAAAAACCATTTGAATGCGTCGTTTGTAAAAAACAATTCCGCCAGTCTAGCACGCTCAATAATCATATAAAAATACACGTTATGGATAAGGTCTACGTGCCTGTTAAGATAAAAACGGAGGAGGAGGAAGGGTGA
Protein Sequence
MHLASSGGSGGGGSRDPSGNPEKPFQCNVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHMKIHTGEKPYNCTYCPKHFRQLSTLANHLKIHTGEKPFECVVCKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEEEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00892129;
90% Identity
iTF_00892129;
80% Identity
iTF_00892129;