Lvar002723.1
Basic Information
- Insect
- Leucophenga varia
- Gene Symbol
- -
- Assembly
- GCA_018903435.1
- Location
- JAEIFJ010002120.1:45865-50254[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 9.3 7.4e+02 1.3 5.9 3 18 133 148 131 148 0.88 2 16 0.0038 0.3 12.0 0.6 1 21 161 181 161 184 0.89 3 16 6.7 5.3e+02 1.8 0.1 1 23 198 220 198 220 0.87 4 16 0.0013 0.11 13.4 0.3 2 23 238 259 237 259 0.96 5 16 3.2e-05 0.0025 18.5 2.7 2 23 363 385 362 385 0.95 6 16 0.0029 0.23 12.3 0.3 1 19 392 410 392 410 0.97 7 16 0.0023 0.18 12.6 0.0 1 23 437 459 437 459 0.96 8 16 0.01 0.82 10.6 1.5 2 23 479 501 478 501 0.94 9 16 0.06 4.7 8.2 0.1 1 23 541 563 541 563 0.95 10 16 0.0007 0.056 14.3 1.3 1 23 580 603 580 603 0.96 11 16 5.7e-05 0.0045 17.7 0.2 2 23 627 648 626 648 0.97 12 16 4.7e-06 0.00038 21.1 1.8 1 20 654 673 654 676 0.95 13 16 2.2e-07 1.8e-05 25.3 0.9 1 23 682 704 682 704 0.98 14 16 0.00029 0.023 15.5 0.6 1 23 710 732 710 732 0.99 15 16 7.7e-08 6.1e-06 26.7 1.6 1 23 738 760 738 760 0.99 16 16 0.00021 0.017 15.9 0.3 1 23 766 788 766 788 0.98
Sequence Information
- Coding Sequence
- ATGCATAAAGAAAATGTTACAATAAAAAATGAAATAGATTATGAAACTCAAAATGATTATTACGCCATAAAAACGGAAATAGAAATAGCTGAAGATCCAATGGAATGCAATGCAATGTCAACTAAATTAGAAAATTATGAATCTGCGCCAATTGATGATGCAAACCAAACTGATTCGTTACTTTTTGCTTACTTAAACAACAATATACAAATTAAAAGTGAAGCTGAGGCTGAGTCTAAAGTTTTAAAACGTCCGTGTCCACCTTTAGTATATTATGAAACTGAAACACCAGGTACCGAGCCACATTTAAATAGCGTTTCTTCCACAGATCTTGAGGCGACAAATCTGCATAATAGTGAGTTAAAGCACAACAGCACTGAAGCCGCCCAAACATGCTGTATGTTTTGTGGCAAATTTTTTAAGGAATCATACTGTTTGAAGCGGCTTATACAAAGTGTGCATTCAGCTGTTGATCGGCCTTATGCATGCGCTAATTGTAGTTATCGTTTTAAATCGCTTAAACAACTTAAGGCACACAACTCAGCTGAACACAACATAACTATCGCACATATAGATAATAATGTTTCACAATTTACTTGCGACGAGTGCGCCTTTGTTCTACTGAACGCTGAAGCATTGGTAAAGCATAAAGATTTACATAAAACGCTAACTGCTGTACAACCGGAGTTGGCACAAAAGCTACTTGGTTTGTCTTGTGAAGTATGCGGCAATGTATTTGGAACAAGACTTAAGCTACAAAATCATAGAAAAATACATAATGACGCCAATAAAAATAATACAACGTGCGATTCTACGTCTTTGATGCCAGAAGTTGAACCTCAAAGTCCAAACAACTCAAATGCATATTCAGCGTCAATGACAAAATTGGAAGACGATACTGAATATGAAGATATTAACAAAGCAAATGATGATTCTCTCTTATTGAAACCTGATCCTGAGTTTAAAGAACTAAACAATTCTGAGTCCAATACTTTGTTGACGAACTCAGCCACTGAACATAAAAATTCAGACAATGCAAATGAAGATTCTTCCTTGTTACCAAGCAATACCTACGGCATACAAACTACATGTACGATTTGTGGCAAATATTTTGGCTCATCTTATTGTTTAAAGCGACATATGACAAGCGTGCATTCATCTATTAATCGCCCTTATGTTTGCACGAAATGTGGCTACCGTTTTAAATTGTTAATACAACTCAAAGCACACGACTCAGCTAAACATAATATATTTACAGTAGCTATAAATGATACGAATGAGGATGTTGATGCTGATTTTGTTGAGAAATTTGCATGCGATGAGTGCGGTTTTGTGCTAAATAATGCTGCAGCATTGGCTAAGCACAAAAATTTACATAAAACCCTAAATGCAACGCAACAATCTGAGGAGTTATCAACTGAAATACTCAGTTTGTCTTGTGATGAATGTGGCAATGTTTTAAGTTCAAAACAAATGTTACGAAATCATAAGAAGCATGATCATCAGGAAAGCAGCAAAAATAATCATACGACGACGGTAAAAAGAAATTTATTTGTACAGAATGTGGAACACAACAAAACCTCAACTTGTACGAATGATATGGATACATTTTTTGATGATTTTTCATGCAATGAATGTGAATTCGTTGCTAATAATGCAATAGCGTTGACAAAACACAAAGGTATACACGAAACTTTAGCAGGTACCACAGCAGACTTGGCAGTCGAGGCACTCAGTTTTTCATGCGAAGAATGTGGCAATGTATTTGGCACAGAAAATATGCTTAAAAATCATAAGCGACATCTGCATACGTATTTAAATCAGACGAAAAAACTTAAAAAACAAACTATCGTCAAAACAAAAAGTACTGAAAAAGTTATGTGTCCCGATTGTGGTAAATATTTCTCTAGCAACAGTGTGCTGGGTGAACATCGAAAGCGTCATAAGCATGGACGTCCCTATGTATGCTCCATTTGTCCAATGGCCTTTACGAATTCTAGTAATCTAAATCATCATATGATCTGTCACAGCGGCGTAAAGAAATATATCTGCGATATATGCGGCAAAGGTTTTACACAATCTTATTCGCTGAAAATTCATAAAAGACGTCACACCAATGAGAAACAATTCAAATGTGATCAGTGTGAGCTGAGCTTTGTTGTACAAGCCACTTTAGATAGTCATAAGCGTACGCATACTGGCGAGAAACCGTACAAATGTAAATATTGCGAATATGCTTTTGCTCAAAGTTACGATCTTCGAAAACATATGCGTATACATCTTGGCGAAGAAGTTTATACTTGTGATTTTTGTCCACAAGGATTTCGTTTAGCTACGGAACTGCGGAAACATTTAATGGAACATAAAAACGAGGATGCTGCGACAAAAGAAAAAAATTTTGCTGCGCGTCAAGAAAAAGAGGCGAAACTAAATTTAAAACTTTATCCTTTTCCAATGCAGAATGGTGTTATAAATGATAAGCGGCAACCAGATACCCTCAAACTTCAATCGCTCTGTGATTATGCAGATGAAGCGATTGGTGCCATGACTATTGCCGAAATATACAAAGCATCGGCAACGGCGTCGGCTTTGAAAGATATTAAAATCTATAAGAAACGTATACGTTCCGTTGCACGTGAATACAGCATTGATAAAAGTAATCTAACGCGTCGTATTGCTGCGTATACACACAATATTTCATAA
- Protein Sequence
- MHKENVTIKNEIDYETQNDYYAIKTEIEIAEDPMECNAMSTKLENYESAPIDDANQTDSLLFAYLNNNIQIKSEAEAESKVLKRPCPPLVYYETETPGTEPHLNSVSSTDLEATNLHNSELKHNSTEAAQTCCMFCGKFFKESYCLKRLIQSVHSAVDRPYACANCSYRFKSLKQLKAHNSAEHNITIAHIDNNVSQFTCDECAFVLLNAEALVKHKDLHKTLTAVQPELAQKLLGLSCEVCGNVFGTRLKLQNHRKIHNDANKNNTTCDSTSLMPEVEPQSPNNSNAYSASMTKLEDDTEYEDINKANDDSLLLKPDPEFKELNNSESNTLLTNSATEHKNSDNANEDSSLLPSNTYGIQTTCTICGKYFGSSYCLKRHMTSVHSSINRPYVCTKCGYRFKLLIQLKAHDSAKHNIFTVAINDTNEDVDADFVEKFACDECGFVLNNAAALAKHKNLHKTLNATQQSEELSTEILSLSCDECGNVLSSKQMLRNHKKHDHQESSKNNHTTTVKRNLFVQNVEHNKTSTCTNDMDTFFDDFSCNECEFVANNAIALTKHKGIHETLAGTTADLAVEALSFSCEECGNVFGTENMLKNHKRHLHTYLNQTKKLKKQTIVKTKSTEKVMCPDCGKYFSSNSVLGEHRKRHKHGRPYVCSICPMAFTNSSNLNHHMICHSGVKKYICDICGKGFTQSYSLKIHKRRHTNEKQFKCDQCELSFVVQATLDSHKRTHTGEKPYKCKYCEYAFAQSYDLRKHMRIHLGEEVYTCDFCPQGFRLATELRKHLMEHKNEDAATKEKNFAARQEKEAKLNLKLYPFPMQNGVINDKRQPDTLKLQSLCDYADEAIGAMTIAEIYKASATASALKDIKIYKKRIRSVAREYSIDKSNLTRRIAAYTHNIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00892059;
- 90% Identity
- -
- 80% Identity
- -