Lvar002721.1
Basic Information
- Insect
- Leucophenga varia
- Gene Symbol
- -
- Assembly
- GCA_018903435.1
- Location
- JAEIFJ010002120.1:37978-41032[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 2.3e-05 0.0018 18.9 2.0 2 23 132 154 131 154 0.95 2 17 0.0034 0.27 12.1 0.6 1 21 161 181 161 184 0.89 3 17 6 4.8e+02 1.9 0.1 1 23 198 220 198 220 0.87 4 17 0.0012 0.095 13.5 0.3 2 23 238 259 237 259 0.96 5 17 2.9e-05 0.0023 18.6 2.7 2 23 325 347 324 347 0.95 6 17 0.0026 0.21 12.5 0.3 1 19 354 372 354 372 0.97 7 17 0.0065 0.51 11.2 0.0 1 23 399 421 399 421 0.94 8 17 0.057 4.6 8.3 1.0 2 23 441 463 440 463 0.94 9 17 0.0031 0.25 12.2 2.2 1 23 479 502 479 502 0.97 10 17 0.026 2.1 9.3 0.1 1 23 524 546 524 546 0.96 11 17 0.032 2.5 9.0 1.0 1 23 563 586 563 586 0.95 12 17 3.8e-05 0.003 18.2 0.3 2 23 610 631 609 631 0.97 13 17 1.1e-05 0.00085 20.0 1.8 1 20 637 656 637 659 0.95 14 17 4.7e-06 0.00037 21.1 0.6 1 23 665 687 665 687 0.98 15 17 3.6e-06 0.00028 21.5 2.0 1 23 693 715 693 715 0.99 16 17 1.5e-05 0.0012 19.5 1.3 1 23 721 743 721 743 0.98 17 17 0.00035 0.028 15.2 0.2 1 23 749 771 749 771 0.97
Sequence Information
- Coding Sequence
- ATGCATAAAGAAAATGTTACAATAAAAAATGAGATAGATTATGAAACTCAAAATGATTATTACGCCATAAAATCGGAAATAGAAATAGCTGAAGATCCAATGGAATGCAATGCAATGACAACTAAATTAGAAAATAATGACACTGCGCCAATTGATGATGCAAACCAAACTGATTCGTTACTTTTTGCTTACTTAAACAACAATATACAAATTAAAAGTGAAGCTGAGGCTGAGTCTAAAGTTTTAAAACGTCCGTGTCCACCTTTAGTATATTATGAAACTGAAACACCAGGTACCGAGCCACATTTGAATAGCGTTTCTTCTACAGATCTTGAGGCGACAAATCTGCACAATAGTGAGTTAACGCACAACAGCACTGAAGCCGCCCAAACAAGCTGTATGTTTTGTGGCAAATTTTTTAAGCAAACATACAGTTTGAAGCGGCATATTCAAAGTGTGCATTCAGCTGTTGATCGGCCTTATGCATGCGCTAATTGTAGTTATCGTTTTAAATCGCTAAAACAACTTAAGGCACACAACTCAGCTGAACACAACATAACTATCGCACATATAGATGATAATGATTCACAATTTACTTGCGACGAGTGCGCCTTTGTTCTACTGAACGCTGAAGCATTGGTAAAGCATAAAGATTTACATAAAACGCTAACTGCTATACAACCGGAGTTGGCACAAAAGCTACTTGGTTTGTCTTGTGAAGTATGCGGCAATGTATTTGGAACAAGACTTAAGCTACAAAATCATAGAAAAATACATAATGACGCCAATAAAAATAATACAACGTGCGATTCTACGTCTTTGATGCCAGAAGTTGAACCTCAAAGTCCAAACAACTCAAATGCATATTCAGCGTCAATGACAAAATTGGAAGACGATACTGAATATGAAGATATTAACAAAGCAAATGAATATTCTTCCTTGTTACCAAGCAATAACTACGGCATACAAACTACATGTACGATTTGTGGCAAATATTTTGGCTCATCTTATTGTTTAAAGCGACATATGACAAGCGTGCATTCATCTATTAATCGCCCTTATGTTTGCACGAAATGTGGCTACCGTTTTAAATTGTTAATACAACTCAAAGCACACGACTCAGCTAAACATAATATATTTACAGTAGCTACAAATGATACGAATGATAATGTTGATGCAGATTTTGTTAAGAAATTTGCTTGCGATGAGTGCGGTTTTGTGCTAAATAATGCTGCAGCATTGGCTAAGCACAAAGATTTACATAATACGCTGAGTGCAACGCATCAACTTGAGGAGTTATCAACTGAAATACTCAATTTGTCTTGTGAAGAATGTGGCAATGTTTTGGGTTCAAAACAAATGTTACGAAATCATAAGAAACATGAACATCAGGAAAGCAGCAAAAATAATCATACGACGACGGAAAAAAAGAAATTTATTTGTACAGAATGTGGTAAACAACTTTCATGCAAACGTTCGCTGAGAGATCATATGCTGACGTTACACAAATTAAAGGAGCACAACAAAACCACAACTTGTACGAATGATATGGATACATTTTTTGATGATTTTTCATGCAATGAATGTGAATTCGTTGCTAATAATGCAATAGCGTTGACAAAACACAAAGCTATACACGAAACTTTAGCAGGTACCACAGCAGACTTGGCAGTCGAGGCACTCAGTTTTTCATGCGAAGAATGTGGCAATGTATTTGGCACAGAAAATATACTTAAAAATCATAAGCGACATCTGCATACGTATTTAAATCAGACGAAAGAACTTAAAAACAAAACTATCGTCAAAACAAAAAGTACTGAAAAAGTTATGTGCCCCGATTGTGGTAAATATTTCTCTAACAACAGTGTGCTGGGTGAACATCGAAAGCGTCATAAGCATGGACGTCCCTATGTATGTTCCATTTGTCCAATGGCCTTTACGAATTCTAGTAATCTAAGTCATCATATGATATGTCATAGAGCTATAAAAAAATATGTATGTGATATATGCGAAAAAGGATTTACACAAGCTTACTCATTAAAAGTTCATAAAAAGCAACACACTAATGATAAAACATATAAATGTGATCAGTGCGATAAGAGTTTTTTTGTGCAAACTACATTGGATAGTCATATGCGTACGCACACCGGAGAGAAACCGTACATTTGTAAATATTGCGCTTTTGCTTCCACACAAAGTTATAATCTTCGAAAACATATGCGTATACATCTTGGCGAAGAAGTTTATACTTGTGATTTTTGTCCGCAAGGATTTCGTTTAGCTACTGAACTGCGCAAACATTTAATCGAACATAAAAATGAAGATGTTGCAACAAAAGAAAGAAATTTAGCGGCACGTCAAGAAAAAGAAGCCAAACTGAATTTAAAACTGTATCCGTATGCATTGCAGAATGGAGTTATCAATGATAAAAGGCGTATAGAAAAAATAACGAAATAG
- Protein Sequence
- MHKENVTIKNEIDYETQNDYYAIKSEIEIAEDPMECNAMTTKLENNDTAPIDDANQTDSLLFAYLNNNIQIKSEAEAESKVLKRPCPPLVYYETETPGTEPHLNSVSSTDLEATNLHNSELTHNSTEAAQTSCMFCGKFFKQTYSLKRHIQSVHSAVDRPYACANCSYRFKSLKQLKAHNSAEHNITIAHIDDNDSQFTCDECAFVLLNAEALVKHKDLHKTLTAIQPELAQKLLGLSCEVCGNVFGTRLKLQNHRKIHNDANKNNTTCDSTSLMPEVEPQSPNNSNAYSASMTKLEDDTEYEDINKANEYSSLLPSNNYGIQTTCTICGKYFGSSYCLKRHMTSVHSSINRPYVCTKCGYRFKLLIQLKAHDSAKHNIFTVATNDTNDNVDADFVKKFACDECGFVLNNAAALAKHKDLHNTLSATHQLEELSTEILNLSCEECGNVLGSKQMLRNHKKHEHQESSKNNHTTTEKKKFICTECGKQLSCKRSLRDHMLTLHKLKEHNKTTTCTNDMDTFFDDFSCNECEFVANNAIALTKHKAIHETLAGTTADLAVEALSFSCEECGNVFGTENILKNHKRHLHTYLNQTKELKNKTIVKTKSTEKVMCPDCGKYFSNNSVLGEHRKRHKHGRPYVCSICPMAFTNSSNLSHHMICHRAIKKYVCDICEKGFTQAYSLKVHKKQHTNDKTYKCDQCDKSFFVQTTLDSHMRTHTGEKPYICKYCAFASTQSYNLRKHMRIHLGEEVYTCDFCPQGFRLATELRKHLIEHKNEDVATKERNLAARQEKEAKLNLKLYPYALQNGVINDKRRIEKITK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00892061;
- 90% Identity
- -
- 80% Identity
- -