Basic Information

Gene Symbol
-
Assembly
GCA_035044805.1
Location
JAWNNP010002837.1:918320-921484[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.00017 0.011 16.5 4.2 1 23 227 249 227 249 0.98
2 17 0.00025 0.016 16.0 3.4 1 23 257 280 257 280 0.98
3 17 0.47 29 5.7 0.9 2 23 317 338 316 338 0.94
4 17 9.7 6e+02 1.6 1.5 1 23 420 444 420 444 0.82
5 17 8.9 5.5e+02 1.7 1.4 1 20 451 470 451 472 0.89
6 17 0.068 4.2 8.3 3.7 1 23 481 503 481 503 0.95
7 17 0.00014 0.0088 16.8 1.4 2 23 511 533 510 533 0.95
8 17 0.00064 0.04 14.7 1.6 2 23 540 561 539 561 0.96
9 17 0.014 0.84 10.5 0.1 2 21 588 607 587 608 0.93
10 17 0.0048 0.29 12.0 3.3 1 23 658 681 658 681 0.97
11 17 0.0091 0.56 11.1 1.4 2 23 719 741 718 741 0.96
12 17 2.8e-05 0.0017 19.0 2.2 2 23 780 802 779 802 0.94
13 17 0.0003 0.019 15.7 0.1 1 23 817 839 817 839 0.95
14 17 0.00036 0.022 15.5 2.2 1 23 845 867 845 867 0.99
15 17 4.5e-06 0.00028 21.5 2.0 1 23 873 895 873 895 0.97
16 17 0.0002 0.013 16.3 3.3 1 23 901 923 901 923 0.98
17 17 0.00013 0.0082 16.9 0.2 1 22 929 950 929 953 0.90

Sequence Information

Coding Sequence
ATGTCTTTGTGCCGCACTTGTGATACAAGTTCGGCCACTGAGCTGTACGAGCTCAAATCGCCGTATAACGTTAAATATCCCGGAAAGCAGCTATTAGACTTATTAACGGAATTAGTTGAGATTAATCAAAATATGGCATACGAATCGCAATTGCCGCAACAAATTTGTGGCAACTGCACACAGAAACTAAACAACGCGTACGATTTTATGTTGCAAGCGCGTGAGGCAAATCAGCGACTGCTGGACGGTCTCAAACCGGACGTAAAGTTAAACACGAACGAATGCTGTTTAGAAGAACTGCCGCTGGAGCAGTTTGTTGCTGTAAAATTAGAGCCCGCTGGCGAAGAGGCAACACCCATGGAATTCGCTGAAACACTTATGGAGAGTCATGACTCAGATCAGGACgacaatgacgatgatgatgtgcGGAACGACTTTGATATGCTTGATGAAGCACGTAGTGAGAGCAGTGCCGATGAAAAAGATGAAGAGGGTGATGATCCCTTAACACTaatgaaacaaagaaaagtTAAAGCACAGCCAAAAACGAAAGACTTgcatgttgatgatgatgaaggcGACGATGATGCCAGCTCCAGTGATGATGATGCGCCACTGCTCCAacgcaaacaaaaaatgcaaaaagctaAGCTGAAGCAAGTGAAGAAAGAGAAACCATTTACCTGCGAAGAATGCGGCAAATCTTTCCGGTTGGAACGCAGCCTGAAAACACATAAGCACAAACATGTGCCGAAAAGCAAAGAGAGCCATCAATGTACACAATGTGCACGTAAATTCAGTCGTCTGCAAACGTTGCAGCAGCATTTGAAGACAGCACATTCGTCGGCCGATGGAGCGCCACAACAAAAAAGCGCAACACTTTCCGCACGCAAGTTGGCTAAAGGACTCGACATGAATCTTTGCAAGCCACACGGCTGCAAGGTGATACAATGCATGATTTGTATGCaacattatacaaaaatttccgAATTGCGTAATCATTTAACTGCACATCCCGAAATTGACACGTTCTCGCGACGCACAGAAACGCTACAAGAGATTAAAGAATCATTCTATCCTGATCTGAAAGAAGAAATTACCGAGGCAGCATTAGTGGCACGCATTAACAAAGATTTAAAAGAgggcaaatatgtatatttctatTCGATAACCAATCAAGCGGGTTACGAGTTACGCTTAGAAAGTTCAGACTCGGATAGTGATGAAGATGGTGAAGTGGTGCCGAAAAAGCATTCCTATGCATGCGAGTTGTGCGCGAACATAAAATATCATCGCAAATACCAACTATTCGAACATCAGTTGGAGAAACATTCCTGGGAGGAGGCACAACATGTCTGCCGGCGTTGTGATGCGCGTTTCCTTAGCAAGCAAGTATTGCAGCATCATTACGAGTCACAATGCCGTAATTCGCAAAAACGTTTTCTTTGCAATCGTTGTCCGCTACGTTTTCGCTGGCGACACAATCTTAAATCACATTATAGAGATCACAGATCTAAGccGACCGCACTTATGTGCGAGCACTGTGATCGAAGCTACGACGACAAGAAATCATTAACAATACACAAGCTAACAGTTCACACCGCATCGACGTTAATGCCCTGCCTCTGGTGCAATCGTAAGTTCTATCGACGCGACTACTTTGTTAAACATCTTAAGCGTCATGGACTGAAGGAACACGATCTGCCACTAGCTGAGACGCTAATTAAAGCTACAGCACAGCCCAATGGCGCTAAGCGCATCAGTTGCAAGGTCTGTCATCTGCAATTCGAACGTATTGTGGATCTACGAGCACATATTTTAATGGAGCTCAAGTTGAATTTAAGCGCACATCAGAGTTACGACTCCTTGACCAACTACTCCATAACAAACGAGTCTGGCTTTGAGTTGCATCTGGATGACTCGGAAACGGATAACGATGATTCGGCAGCCAGTACAATGCACTCCATACCATACAAATGTGAAATTTGTCAAGTGCAATGCCGCCGGCGCTACGAAATGTTTCAGCATCAACGTGCAATGCACTGCCGTGATCCAATGCCGCATACATGCgacaaatgcatatttaaatgtgTAAACAAGCGCATACTCGAGCATCATCTGCAGACACAATGTCAGAACCCATTTAAGCAGCTAAGCTGCGAGCACTGTAACTATAAATTTATGTGGCCCGAAAACTTGGAACAACATCGTCAAACGCAACATGCTGGCGCATTTGAGAACAAGAGTGCTGTTGCGGCAAGCATTTCTGTAGTAAGTGGTGATTCGCCAACCAAGACAGCGCAAACTGAGACAAAAGCAGCACCAGTAGCTCTATTAAACTGTCCACATTGTGATCGTACCTACATGCATCAATCGTGGCTTAGAAATCACATACGCGATGTACATAGCGAAGctggcaaaaagaagaaaaaagagtCTGAAGTCAAATTTCTTTGTTCACTATGTGGCAAAGAGGCATCATCGGCTGCTGCCTTGGTCACGCACATGCGTCGTCATACTGGCGAAAGACCGTACAAATGTGACATGTGTGAAATGGGCTTCCCAAGGCATAGTGAGATGCTGCAGCATCGCCGAAAGCACACTGGGGAAAAGCCATACCATTGTACCGTTTGCGGTAAAGATTTTGCGCGTTCCGACAAATTGAAGCGGCATACGCTTATACACAGCGGTCTTAAACCGTACAAATGCACATTCTGCGAGAAAAGCTATCGCCAGACTAAGGATCTTAAGCTACACTTACAACAACATACCGGAGAAACGCCATTCGAATGCTCCACATGCGGTGAGCGTTTCATACAGCGTGTTGCACTGGAGAAACATCGTATTATGCGTGGACACTTCGAAGAGATACAGTAG
Protein Sequence
MSLCRTCDTSSATELYELKSPYNVKYPGKQLLDLLTELVEINQNMAYESQLPQQICGNCTQKLNNAYDFMLQAREANQRLLDGLKPDVKLNTNECCLEELPLEQFVAVKLEPAGEEATPMEFAETLMESHDSDQDDNDDDDVRNDFDMLDEARSESSADEKDEEGDDPLTLMKQRKVKAQPKTKDLHVDDDEGDDDASSSDDDAPLLQRKQKMQKAKLKQVKKEKPFTCEECGKSFRLERSLKTHKHKHVPKSKESHQCTQCARKFSRLQTLQQHLKTAHSSADGAPQQKSATLSARKLAKGLDMNLCKPHGCKVIQCMICMQHYTKISELRNHLTAHPEIDTFSRRTETLQEIKESFYPDLKEEITEAALVARINKDLKEGKYVYFYSITNQAGYELRLESSDSDSDEDGEVVPKKHSYACELCANIKYHRKYQLFEHQLEKHSWEEAQHVCRRCDARFLSKQVLQHHYESQCRNSQKRFLCNRCPLRFRWRHNLKSHYRDHRSKPTALMCEHCDRSYDDKKSLTIHKLTVHTASTLMPCLWCNRKFYRRDYFVKHLKRHGLKEHDLPLAETLIKATAQPNGAKRISCKVCHLQFERIVDLRAHILMELKLNLSAHQSYDSLTNYSITNESGFELHLDDSETDNDDSAASTMHSIPYKCEICQVQCRRRYEMFQHQRAMHCRDPMPHTCDKCIFKCVNKRILEHHLQTQCQNPFKQLSCEHCNYKFMWPENLEQHRQTQHAGAFENKSAVAASISVVSGDSPTKTAQTETKAAPVALLNCPHCDRTYMHQSWLRNHIRDVHSEAGKKKKKESEVKFLCSLCGKEASSAAALVTHMRRHTGERPYKCDMCEMGFPRHSEMLQHRRKHTGEKPYHCTVCGKDFARSDKLKRHTLIHSGLKPYKCTFCEKSYRQTKDLKLHLQQHTGETPFECSTCGERFIQRVALEKHRIMRGHFEEIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00891171;
90% Identity
iTF_00891171;
80% Identity
-