Lcom035968.1
Basic Information
- Insect
- Leucania comma
- Gene Symbol
- egg
- Assembly
- GCA_958295575.1
- Location
- OY282491.1:4441556-4485724[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 5.2 2.1e+04 -3.7 0.1 29 38 2029 2038 2001 2039 0.67 2 2 4.9e-13 2e-09 38.1 0.0 4 73 2070 2132 2067 2136 0.88
Sequence Information
- Coding Sequence
- atgaGTGATCAAGAAGGAATGGATACTAATACTGAAGATAAAGGcaacgaaatctcagaaataaTAACTCAGGGTCTTGTTAAAACTAACGAATCTCCAAGTTCAGGTGTTCAGGTGTGTGGGAGTTCTTCAGGTGTAGAAGATTGTGGAGACGGTATAAGTCGCATTTCACGAGAAAACTTGATAAAATCTGATATTACTGAatcagatttgaaaaaaaatgctcaGAAATTGATAAACACTGATGCAGGCAAAAGTACTGGTGATTATACAGCCACAGAAAAGGTCATTGACATGgatgataaaaatattgtagacaTAAATATTGATAGTGGTGCAAAAACATCTGAATGTAATATTACTGAGAAAGCTGAAAGCAGCATCAGTATTCTTGCCAAACATGACATACTTGAGCTCAAAAAGGCTGATGATCTTGACGAAATTGAAGATGAAGATATAGCACTTAGAtgggatgatgatgatgatgacggtaGTAATCTAGCTGTTAGGCATGGAGATGGTAAGGCTGATGCTGGAAATGAGGATATTCTGTCAGAAGAACAACTTTTAGAAGAACCTTGGCAAGTTGTAACTGAAGAAATATCTAAGAGTTCTGAAGACATGTTAAAAGGTAAGGCTGAAGAAAATATTGTAAGTAAAAACAAATCTGAAAAAGAAATTGACACTACAAATGAATTTAAAGTTCATCCAAAACTGGACATTCCTCCAGAAAAGGTTGAAGATGAAGAAAGCTTAGAAGACGAACTTCTAAAAGAACCGGACTTAAATACAGAATCAATAAATAGCTCAGAAATGGATTTTGATGTTTTGCAAGAACATGAGGACATAAATACTGAAATGATAAATAGCCCAGAGATGGACTTTGAGGTTTTGCAAGAAACTGATTTGAATGCTGAAGAAATAAATAGTCCTGAAAATTCTCAAAATTTCATAGAAGAAAATGTGGTTCTGGTTGATAATGAAGATAAATCGGTAGAAGAATCTGAAATGGAAGTAATACCTCAGGCTAAAGAAATTCTTGGAGAGAAGAGTGTGGTTGAAAAACAAGAAATATGTGATAAAGACAAGACAATGAAAGTAATAGCTGAGTCTAAATCTCTTCCTGAAGAGGAAAGTATGGTTGAAGAAGTAATTGCCTGCACAAAACAAGTATTAGCTGAAACTAAAGAGATTCTTGGGGAGGAATGTGTTGAGAAAGAAGTACAGGAAACTGAAAATAACAATGCAAATCAACTCATAACTGAAGATAAATCCCTTCTTAAAGAACAAAGTATGGTTAAAGGAGGAGATAAATCTGAAATAGATAGTGCAAAACAAGTAATGGTTGAAGCTAAAGAGACTCTTGAAGGAAAAAGTATAGTTGAACAAATAAAAGAGACAGAATCTGTAGAAATTAAACATGCAGAAGAAGTTCCAGAAGGTAGAATAGAAGATCAGCTTTTAGCAGAATCTGACAATACTGCTGAAAAAGTGATTAGAACTTTCAAAATGTCATCTTTGACAGATGTCgtcttacaaaacaaaaatgatgatgttatgttgaaagaaaaacttttaaaagaaGTTGACTCTAATATTGAACATTCTGAAGTAGGTGAAAAAGAACTACCACTGAATAAAGAAGATGATGTTCATTTAGAACGTAAAGTATTAGAAGAAACTGAAACAGTTGCATTAATTCCTGAAAGTGACGTAACAATGGATGTGGATGATGACAATGAAGGAGAATTACTGAAAGACAATGACTGTCAAGACTACAAGGGTACTGCTATGGATATTGACATTTCTGATCAGTCTATTGAAGACCAAGATAAGTTGGAAGATAAGATTTTAGATCAGCCAATGGGTGACCAATCTGAAATGACAAATAAAGATATTTGCATAGTTAATGAAACTAATATAGAAAAGGTTCATTTAGATGAaccagaaaataaaattaaaagtaaggAACAATCTGATGACCAAGCCAAAACGGTTGATATTACTGAACTCCCGATTGACGAAACAACTGAAACAGTAGAAGCAATTAAAGAGACACCTGAAGctaaaattgaagaaaaagtTATAGTTACAACTAAATCTAAAACTGAAAATGTTGATCAACCAATGaatgatgaaaataaaattgaagacaACAATCAAGAAGTATTAACTCTTGACACTAATATTACAGAACAGTCAGTTAGAAGTCCTGAGCTGACAGCTGAAACCACTGTTTCTAGGTCTCCTAATGTTATAACTGAAGATCTAGAAAAATCAATGCCAGAAAATACTACACTTGTAACAGaaacaaatgataaaataaaggCCAAAAAACCTGAAGAAACAGAAAGTGCATATAATGTCTCTGATTTAAACAAAcccaaagaaataaaagaaaatgtagacacagtcacaaacttaaataaaaataatgaagattCACCTAAAAACTCTTCAACATTTTTCGAAGATTCACCATTGCCTATCAAAACCAACCATGGTTTACACAAACCAGATGTAATGCTAGAAATACCAACACAAGAACTTATAGACATAGATGATACAGACTTTTCTATGAATTTAGATCAATCTGACATTATGGTTGATCTGAATGATGTTTATGAAGAGACAGAATTTGAGggaaaaatagataaaattgtCTCTGATAATGATAAATCAGAAGACCAAGTCATAAATGAAAATGACACAGCAAATGAAAAACCAGCAGATCAAAAAGCTTCAGTAGATAAAATTATAGCTGATAATGACACTGTGaaagaaaaatcaataaatcagACAACTGAAGTTACTGAAACAACAACTTCCACTGAAGATGACACACAAAATGACGAATCAGTAAAACAGAAAGCTGAAGCAGCAATTGTCACTGATGATGCCACAGTAAAAGAGAAATCAGTAGATCAAGATGCCACAGTGAGTGAGTCTACAGCACGTGAACTCAAAAAAGACAGCGAAATTGTGAAAAATAATGAGAAAGTTGAATGTGCTGCTGTACCAACAACTATTGAAGAAAATATGCAGAAAATTTTTGCAGATGGCGAGCCTGATGTTGCTAAAGAAGTTCCAGAATGTATTGCAACCACAAGCCAAGCTCACCTCCCCGCTGAACATCCACCAACATCCACTCAGATGACACCTGACACATCAGATGAAGTACCAGAGATATCTGACAGTCTTGGCCTGCTAGCCGAGTCGGCCGGACGCATGATGGAGGACGATGAGGAGCccgaagatgatgatgacggcgatgatgatgatgattttgataATGATGAAAGCAGCAACCAAATCTCAGCGGAACAGTCAGAAGACTCGAACCCTGCAGCTTTAGACGCTGAACCGGCAGTGGAACAAGAAGACAAGGACTTGGAGACTCCGGACCCTAATGATGAGGAGGGTCCGTACATGATGTGTGACAGCACGTCTCAGGATAAGACGGAGAAGATGGATGTTGAAGAAGAGTTTGGGACGGTGGAATTACAAGCAGAAACTGTGAATGAGATGAATGAAGAGGCGAAGTCTGCGCAGGAAGATGCGTTGTTGGACGGTGATATTTCGGCCAATGAAAAAGCTGAggaAAAACAAGAACTTAGCGAGCAGATGGACATAGAGACGGTGAAACTGTCTGATACATCTGACAATGAAGTTGATGTTGAACCTACCAAAGTTCAGGCCGTGGCTGGTCCCAGCGGAGAGGGTGAAGACCAAACGTCAAAGCTATCTCAATCTAAACCGCCGTCCAGCCAACACACATCTCCGAAGCAATCACCAAGCAAGCAGGCGCCGTCTCCCAGCAAGCAATCACCAAGCAAAATAAAGAACTTGGCTATAAGTACTCAGGTAGCTAGCTCCGTCGTCAATATCGTGGACCTGGAGGAGAGCAGCTCTTCTGAAGATGACATACAAGAAGTACAGAAACAACCGGAAACTGACACGACGTCAGACGCAAACGAAAAGCCGCCTTCTACAGACCCAGATGTTACCAACGTCAACATACCGCCGGGCATAGAGATTACAAGTATGAGTTCTGGAGGCAACACTTCCGAGATAACGACTAAAGAGGGGGAGGTTGTGATCAGTGGAGTGCCGAAACCTCCGCCCCATAAGCCTGCTAGATTAAATACAAGCGAAGTTTCGATCAAAACTGTTAGCGTCGAACCTATGATTATACCCGCAGCAAAGATAAATGATCAGGCTCAAACTCCAACACATTCTAAGCCTAAACTGAGCCTAGAAATATTCAGCCTAGATTCTGATGACGAAGATAGTTCAGCTCATAAagATCCACAAAAAGTAACGGACCTAGATTTGGAAATGGTCCGGGACATGTCGAAATGCGTCAACTACTGTTGTACGAGCGACGGTAAAGGGCCTTACATAGTGGCGGACGCGTCGGTGGTAGCTTACTACGACGCCGGCAGGAAGAGACGCTCCATGGTGTGTCTGCCGTGTGCCGAGGTGGTCGCTAATAGGACtaagAATCTAATCCAAGGTATAAAAGATTTGACTCCTCTACTGGATCTAGAAATGAGCAAGTTGTCACAAGACTTGGTGGAGATATCGGATTCGGAGTCCGAAGACGAAGATACGACTACAGATGAACCCAAGGAGACTATCGGAGAAAAGGGAGCTTTATTCATAGAAGACAATCTAGCCAAGTTTTTGAACGAAACTTGGGAAAAATACGAAATGGATGTCAGACTTAAAGAGACGCAAATCATGCTGGACGATGAGATTGAAAAACTTGAACaggaCAGCAAGGAAATAGACGCTATGCTAAACGAGTGTCAAGTAGCGACGGACAAGCTTCGCAATGAATTATACGCGACGTTTGAGTGCCGAAGACAACAACTACCCGCCATAGTTATTTGTGATACACCTGAATCTAAATTTATCGGACCAGAAGAGCAGGAATTTACTGTCGTTGAATCAATTGAGACTCGCCAGAACAAGCGTCGTTTGTCTTCGACCACTGAGTCGCCAGCAAAACGTCCGGCCATACCGCTCGGGTATGCACCTTTAGATGGCGGAGATAGtaagGAGAAAGCAGCTGTTCCCGGACCGGATGCCAAAATAGATGATGACAAAGACATATCGGTAGTAAAGCTATCAGCCGAAGCCGCCCCGGCCGAGCTACCGCCCCCGGGCGAGATCTCCCGCCCCCCTCTACGCGTGGGGATGCCCGTCTACTCTATGAAGAACGCTTTCGGACCCTGGCTGAAAGGCCGCGTGCTGGAGATACAGCCTAGGAATCCTGCTGGGggcaACCCGTTCACTCTGTGTCGTATAAAATTCGACCATAAAACGAAGACCAACGGGAAGGTTTTGCCTGCGAGATGCATAGCATATTCAGAGCCCGCTGACGTTAGAATGACTATTGGTACTCGGCTCATAGCCTTGTTCAAGGACACAAACAAGCGCGAATCATACTACTCGGGCGTTGTAGCTGAAATACCAAATCCGGTCAACAATTACAGATACCTAGTGTTTTTCGATGATGGCTATGCCCAATACGTCCAGCATCAATACACTCGTCTGGTCTGCGAGAGTTCACCCCTCGTATGGGAGGAGGTACATCCATTCTCGAGGGAGTTCGTGAAGGAGTACCTGCTGGCGTACCCAGAGAGGCCCATGGTGAGGCTGCACGAGGGCCAGCACCTGAAGACTGAGTGGAACGGAAAATGGTGGTCATCCCGGGTGACCCGAGTGGACGCATCACTAGCTCAAGTGATGTTCGTGGGCGACGGGCGGCGCGAGTGGATCTACCGCGGCTCCACGCGCCTGGCGCCGCTCTACCTGGAGCTGCGCGCCGCCGAGCGCCACCGGCCCAGGCCCATGCCTAGGAGCAAGGTTCAACCCAGACTCAACATGCCTTACGTGGAGTACACGAGGTCTGAGGAGCAGTCGAACAAACAAGACTCGGCTCAGGTTCAGCGGGAGCAACAGCAGCAGATACAAAACGAGGAAATCCGGCGGCAGCGCGCCGTGGCCAAGAAGTCGACGTCGGCGccggccgcgcccgcgccgcccgcgccgccgcccgccacCAACACGGACCCCGTCACCAGCAGAGTTGTGTATTATACTCCAAAGAACGCGGTGAAGCCATTGAAGATGGTCCCACACAGATGTGGGCCAAAATGCAAGCGAAGCGACGTGCTATCCCTAAAAGATTTAAGAACCTATAATCCTCTAGCGAAACCTCTGCTCAGTGGATGGGAAAGACAAATAGTCCGGTTCAAAGGCCACAAGGAAGTGATGTACCGCGCGCCGTGCGGGCGGCGCCTGCGCAACATGCGCGAGCTGCACCAGTACCTGCGCGCCATCGACAGCGACCTGCCCGTCGATCTCTTCGACTTCCACTACTCCACGCACTGCCTGGCGGAGTTCGTGCTCAACAAGTGTCTGGTGGGGAAGAAGGACCTGTCCCACGGCAAAGAGAACGTCCCGGTCCCCTGCGTGAACTACTACGATGACTCGTTACCGGAGTTCTGTTCGTACAACACCGAGAGGACTCCCACCGCCGGCGTGCCACTCAACCTGGAGCCCGAGTTCCTTTGCGGCTGCGACTGCACCGACGACTGCCAGGATAAATCAAAATGCGCTTGTTGGAAGATGACGTTAGAGGGCGCTCGGACCATCGGTCTGGATGGACCTAATGTGGGCTACGTGTACAAGCGGTTGCCTGAACCACTACCTTCTGGAATCTACGAGTGTAATTCTAGGTGTAAATGCAAGCATACTTGTCTAAACCGCGTGGCGCAACATCCACTACAATTGAAGTTGCAGGTATTTAAAACTCCGAACCGCGGCTGGGGTATCCGCGCGCTGAACGACGTGCCCAAAGGTTCCTTCCTCTGCGTGTATGCTGGTAACCTATTGACTGATGCCACGGCTAACTTGGACGGCTTGAACGAGGGCGACGAATATTTAGCAGAATTAGATTATATAGAAGTAGTGGAACAGATGAAAGAGGGATATGAAGAAGACATTCCTGAGGCCGACAAGAAATTAGACAAGAAAGAACGAGGCAAAGCTGACAATGATAGCGAAGAAGATGAACCTTCATCGTCAGAAGAAGAGGACAACGCCTCAAAGACCGACAAAGAAGATGACGACTTTCGACCCGGATACATTGGACTTGGCGTTGCGGAGTTCAGcaAACGCCTCCGCAAACGTGAAAGATCAAAGAAAGGTAAAGCGGCGACTGAcgaaaaagaaaaggaaaaagatACAGCTAAAGACACAAAAGATAATGCTGAAGAGGATTGTATCACTATTAGTGATGATGAAGAAGtAAGAGAACCTTCAAGATTCATGGCGCAAACGAACATGGGAACTAAcgattatatttctaaatacaaATCTGTTCGCACATTATTTGGCAAAGACGAGGCGTGCTACATCATGGACGCTAAGGTTCAAGGCAATATTGGCAGATATCTCAATCACTCGTGCTGCCCGAACGTGTTCGTGCAGAACGTGTTCGTGGACACGCACGACCCGCGCTTCCCGTGGGTCGCGTTCTTCGCGCTGTCGCACATCAAGGCGGGCACCGAGCTCACCTGGAACTACAACTACGACGTGGGCTCCGTGCCCGGCAAGATCCTCTACTGCTACTGCGGCGCGCCCAACTGTAGGGGCAGACTTTTGTAA
- Protein Sequence
- MSDQEGMDTNTEDKGNEISEIITQGLVKTNESPSSGVQVCGSSSGVEDCGDGISRISRENLIKSDITESDLKKNAQKLINTDAGKSTGDYTATEKVIDMDDKNIVDINIDSGAKTSECNITEKAESSISILAKHDILELKKADDLDEIEDEDIALRWDDDDDDGSNLAVRHGDGKADAGNEDILSEEQLLEEPWQVVTEEISKSSEDMLKGKAEENIVSKNKSEKEIDTTNEFKVHPKLDIPPEKVEDEESLEDELLKEPDLNTESINSSEMDFDVLQEHEDINTEMINSPEMDFEVLQETDLNAEEINSPENSQNFIEENVVLVDNEDKSVEESEMEVIPQAKEILGEKSVVEKQEICDKDKTMKVIAESKSLPEEESMVEEVIACTKQVLAETKEILGEECVEKEVQETENNNANQLITEDKSLLKEQSMVKGGDKSEIDSAKQVMVEAKETLEGKSIVEQIKETESVEIKHAEEVPEGRIEDQLLAESDNTAEKVIRTFKMSSLTDVVLQNKNDDVMLKEKLLKEVDSNIEHSEVGEKELPLNKEDDVHLERKVLEETETVALIPESDVTMDVDDDNEGELLKDNDCQDYKGTAMDIDISDQSIEDQDKLEDKILDQPMGDQSEMTNKDICIVNETNIEKVHLDEPENKIKSKEQSDDQAKTVDITELPIDETTETVEAIKETPEAKIEEKVIVTTKSKTENVDQPMNDENKIEDNNQEVLTLDTNITEQSVRSPELTAETTVSRSPNVITEDLEKSMPENTTLVTETNDKIKAKKPEETESAYNVSDLNKPKEIKENVDTVTNLNKNNEDSPKNSSTFFEDSPLPIKTNHGLHKPDVMLEIPTQELIDIDDTDFSMNLDQSDIMVDLNDVYEETEFEGKIDKIVSDNDKSEDQVINENDTANEKPADQKASVDKIIADNDTVKEKSINQTTEVTETTTSTEDDTQNDESVKQKAEAAIVTDDATVKEKSVDQDATVSESTARELKKDSEIVKNNEKVECAAVPTTIEENMQKIFADGEPDVAKEVPECIATTSQAHLPAEHPPTSTQMTPDTSDEVPEISDSLGLLAESAGRMMEDDEEPEDDDDGDDDDDFDNDESSNQISAEQSEDSNPAALDAEPAVEQEDKDLETPDPNDEEGPYMMCDSTSQDKTEKMDVEEEFGTVELQAETVNEMNEEAKSAQEDALLDGDISANEKAEEKQELSEQMDIETVKLSDTSDNEVDVEPTKVQAVAGPSGEGEDQTSKLSQSKPPSSQHTSPKQSPSKQAPSPSKQSPSKIKNLAISTQVASSVVNIVDLEESSSSEDDIQEVQKQPETDTTSDANEKPPSTDPDVTNVNIPPGIEITSMSSGGNTSEITTKEGEVVISGVPKPPPHKPARLNTSEVSIKTVSVEPMIIPAAKINDQAQTPTHSKPKLSLEIFSLDSDDEDSSAHKDPQKVTDLDLEMVRDMSKCVNYCCTSDGKGPYIVADASVVAYYDAGRKRRSMVCLPCAEVVANRTKNLIQGIKDLTPLLDLEMSKLSQDLVEISDSESEDEDTTTDEPKETIGEKGALFIEDNLAKFLNETWEKYEMDVRLKETQIMLDDEIEKLEQDSKEIDAMLNECQVATDKLRNELYATFECRRQQLPAIVICDTPESKFIGPEEQEFTVVESIETRQNKRRLSSTTESPAKRPAIPLGYAPLDGGDSKEKAAVPGPDAKIDDDKDISVVKLSAEAAPAELPPPGEISRPPLRVGMPVYSMKNAFGPWLKGRVLEIQPRNPAGGNPFTLCRIKFDHKTKTNGKVLPARCIAYSEPADVRMTIGTRLIALFKDTNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQYTRLVCESSPLVWEEVHPFSREFVKEYLLAYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKVQPRLNMPYVEYTRSEEQSNKQDSAQVQREQQQQIQNEEIRRQRAVAKKSTSAPAAPAPPAPPPATNTDPVTSRVVYYTPKNAVKPLKMVPHRCGPKCKRSDVLSLKDLRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHQYLRAIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLDGPNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKERGKADNDSEEDEPSSSEEEDNASKTDKEDDDFRPGYIGLGVAEFSKRLRKRERSKKGKAATDEKEKEKDTAKDTKDNAEEDCITISDDEEVREPSRFMAQTNMGTNDYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAPNCRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01031169;
- 90% Identity
- -
- 80% Identity
- -