Lacc014412.1
Basic Information
- Insect
- Lerema accius
- Gene Symbol
- L
- Assembly
- None
- Location
- scaffold580:675192-691818[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.3e-06 7.8e-05 22.9 1.7 1 23 89 111 89 111 0.99 2 17 1.2 76 4.0 4.8 1 23 117 139 117 139 0.97 3 17 7.2e-06 0.00044 20.5 4.1 1 23 145 167 145 167 0.99 4 17 1.5e-05 0.00093 19.5 0.1 1 23 173 195 173 195 0.98 5 17 0.001 0.065 13.7 0.1 2 23 211 233 210 233 0.93 6 17 5.1 3.2e+02 2.1 0.1 9 23 264 279 260 279 0.93 7 17 0.26 16 6.2 0.0 3 23 335 355 334 355 0.97 8 17 0.1 6.2 7.4 0.1 2 23 369 390 368 390 0.91 9 17 0.0017 0.1 13.0 0.7 1 23 398 421 398 421 0.91 10 17 0.028 1.7 9.2 0.1 1 23 426 449 426 449 0.92 11 17 0.0034 0.21 12.1 0.1 1 23 509 534 509 534 0.96 12 17 0.00017 0.01 16.2 0.1 2 23 590 611 589 611 0.96 13 17 0.049 3 8.4 0.0 1 23 619 641 619 641 0.97 14 17 4.5 2.8e+02 2.2 0.7 2 23 649 670 648 671 0.91 15 17 0.1 6.4 7.4 0.2 1 23 745 767 745 767 0.94 16 17 0.002 0.13 12.8 0.1 1 20 775 794 775 797 0.95 17 17 0.12 7.5 7.2 0.3 1 23 804 826 804 826 0.94
Sequence Information
- Coding Sequence
- ATGATCATGCTATTCAAAGGCAACAGCAGCAGGTTGGAACACTTGATAGAGAAAATACAAGCGAATAAAGAAAATCACGACGTCACTACAGAAGATATAAAAGAGGCGCTGGGTAGCGTGGGCAGCACCGCGGCGAGCTCGTGGCCGTCGTCGACGCCGGAGCCGTCGCCATCACCGTCGTCCACGCCGACGTCGGCCGACGCCGCGGACGCCGACGCCGACGCCGAGCCCCCCTTCACACACGGCGCCACCGAACACACCCCCTACCAGTGCCAGTTCTGCGATAAGGCCTTCCCGAGACTCTCCTACCTTAAGAAACATGAACAGACACACACAGATGAGATGCCGTTTCGTTGCGAGTTTTGTGCGCGCCTGTTCAAGCACAAGCGATCGCGGGACAGACATGTCAAGCTGCATACCGGCGACAGGAAGTATCGCTGCGCACACTGCGAATCAGCCTTCTCCAGGAGCGATCACCTGAAGATTCACATGAAAACGCACGATAACCAGAAACCCTTTCAATGCACGGTGTGTAACCGAGGGTATAATACTGCGGCTGCGCTCACGGCTCATATGCAGGGGCACAAACGTGACCGCGAGGGGCGGGAAGCTGAAAGGAGACGAGCACTTCGATGCCTGCGATGTGGAGACGCTTTCAGACGACCCGACATGCTGCAGGCTCATATGGCAAATGCACATGGCGCTGACACAAGCGCAATGACCCCACCTCGAAGAGTAGCTTCACAACCTCCACCAACACTTTTGGCTTGCATCTATTGCACTCGTGACACTTTCACGAGTATGGAACAACTACAACTGCATGTGCGCGCAGCTCACTCTGCGCTTCTGAATGGGGAAACCCCCGTACAGACATCGGTAGAACAACCCGCGCCTACCGATTTAAGTCGAAGAGGGTCGGAAGATGCTCCTACCATTAAGCGTCCACGATTAAGTTCTGGAGGAAACACACCCCAGACGGCCCTATCCCCTAGTACCCTATTATGCAATCAGTGCGATGCTGCCCTGCCTGATTTTGAAGCATTTCGGGCTCATTTAAAAGGTCACCTTGAAGAGGGGGGTGAGTTGAATCGCTCAAGTCCCACGCCGTGTCTGCACTGTGGAGCAACTTTCGCAGATGCAGCGACCTCAGAGCGCCACCTTGCCGCGCATTACCTCGCCGCATCCTGTGAATACACTTGTCACAGTTGTGCGCGCACATTTGCTGCTCCCGATGACTTGCAAAAGCACCTGTTTGATCTGCACGCTCATCATCTCTATCGATGTTCACTTTGCAAGGAGATTTTTGACTCAAAAGTGGCTATTCAGGTCCATTTTGCAGTTGCTCATAGCGGCGAGAGTAAAGTATGGGTGTGTCGTTCCTGTGGGACAAGTGGAGGAGCGCTTCGCTCTGAAGCAGAGGGGGCGGCGCACGTCCGCGCGCGGCATGCTGCGGCGAGGTGCGCGTGCGGCGCGGTGTTGCCCGGCGCGCGCGCACTCCGGGCCCACGCAGCATCGCACCACGCCTACCGTTGCCCCGTCCCAAATTGCACCGATACTTTTGCCGTCCAGTACTTGCTTGAGAGACATATGCAAGCTAATCATACTATTGGTCAACAGCCTCTTAATGGTGAGATGGTCCGAGCGAAAAGAACAGAAAACAATAACGCTGTTGAAGGAGATGGAGCATGTTCACCTTGTATCACCGGTACCGAGGGCAACGGTGTTGGTGTAGAAGAAAGACGACGGAAGAACGGGGCAGTGGCCCTCCAATGTGCGTACTGCGGCGAGCGCACGCGCAGCCGCGCCGAACTCGAAGCTCACACTCGCGCGCACTCCGGCGCGGCCGCTGCGCGTCACAAGTGCCTCATTTGCGATGAAGTGCTACCATCTGCGGCTGTTCTTGCTGAACATAAATTAACCCATTGCAAGGTTGTAGCAGGAGATACTTGTGCGAGATGCAGATCTAGGCTACCATCAGAAGAAGCTTTTCTGAATCATATGGCAAGGCATCATCCCACTCTTCCTGCGCCATGTGTCGTTTGTCGTCAAACTCTTGCCTCAGAGGCCGAGGCACGTCTTCACGCACGTTTCCATCTCCGACCGACAGAAGATGAACAAAGATGTGCGATATGTCTTAGAACTCTGTCGGAGAATGAAGCGGGAGAGGGTGCTAGGGCTTGCTCTTCTTGCTACGCTCGCCACGCAGCACCGAGACCGCCACCATCAAATGAACATGACTGTCGACTTTGCCGAAGAGCTCTCGGTTCACCGACCAGTCTCCAAGCTCATCTTATCGAGCACACGTTTGCTGGTATAGGCGCATTCACCTGTTACTTGTGCCAAGCCGTCTTCACGAGCGCTGCCGGCTTGCAACGGCATTTACCAGAACATGCAGCGGCACCCAGACCGTATGACTGCGGCAGGTGTGGAGTGAAATTCTTTTTCCGTGCCGAATTAGATAACCATGCATTTGTTCATCTGGAGGAAGCTGAGTTGGCACAGCGAGCGTTCTACGAAGCCTACGCTAGGGGCGCCGCCTCGGCTTGGGCTGCTTTGGCTCCTCCCGAGCCAGCTTCTCAAAACTTGGTGTCTACGCCTACTCCAGCTATTACTGATATCCCAGTTAAACGCGAGCCTGAAATTAAAGAAGAACGCAATACAGATGAATATATTGAGGTGTCTTCGCCTCCTCCGCCCCCTCCGCCGGCGGCCCCCTCCCCGCCCCGCGTGGTGGTGAAGCAGGAGAAGCCCGAAGCCGAGTAA
- Protein Sequence
- MIMLFKGNSSRLEHLIEKIQANKENHDVTTEDIKEALGSVGSTAASSWPSSTPEPSPSPSSTPTSADAADADADAEPPFTHGATEHTPYQCQFCDKAFPRLSYLKKHEQTHTDEMPFRCEFCARLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTAHMQGHKRDREGREAERRRALRCLRCGDAFRRPDMLQAHMANAHGADTSAMTPPRRVASQPPPTLLACIYCTRDTFTSMEQLQLHVRAAHSALLNGETPVQTSVEQPAPTDLSRRGSEDAPTIKRPRLSSGGNTPQTALSPSTLLCNQCDAALPDFEAFRAHLKGHLEEGGELNRSSPTPCLHCGATFADAATSERHLAAHYLAASCEYTCHSCARTFAAPDDLQKHLFDLHAHHLYRCSLCKEIFDSKVAIQVHFAVAHSGESKVWVCRSCGTSGGALRSEAEGAAHVRARHAAARCACGAVLPGARALRAHAASHHAYRCPVPNCTDTFAVQYLLERHMQANHTIGQQPLNGEMVRAKRTENNNAVEGDGACSPCITGTEGNGVGVEERRRKNGAVALQCAYCGERTRSRAELEAHTRAHSGAAAARHKCLICDEVLPSAAVLAEHKLTHCKVVAGDTCARCRSRLPSEEAFLNHMARHHPTLPAPCVVCRQTLASEAEARLHARFHLRPTEDEQRCAICLRTLSENEAGEGARACSSCYARHAAPRPPPSNEHDCRLCRRALGSPTSLQAHLIEHTFAGIGAFTCYLCQAVFTSAAGLQRHLPEHAAAPRPYDCGRCGVKFFFRAELDNHAFVHLEEAELAQRAFYEAYARGAASAWAALAPPEPASQNLVSTPTPAITDIPVKREPEIKEERNTDEYIEVSSPPPPPPPAAPSPPRVVVKQEKPEAE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00842895;
- 90% Identity
- iTF_01438254;
- 80% Identity
- -