Basic Information

Gene Symbol
Zfpm1
Assembly
GCA_963675555.1
Location
OY776675.1:78114742-78117834[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 7.8 1.4e+03 2.1 0.1 3 23 8 28 6 28 0.91
2 15 0.065 12 8.7 0.4 1 23 549 572 549 572 0.90
3 15 0.022 4.1 10.2 0.1 2 23 650 672 649 672 0.92
4 15 0.00075 0.14 14.8 1.1 1 23 680 702 680 702 0.98
5 15 0.0076 1.4 11.6 3.1 2 23 705 726 704 726 0.97
6 15 0.031 5.8 9.7 2.8 1 23 732 754 732 754 0.82
7 15 4.2e-05 0.0078 18.7 5.2 2 23 761 782 760 783 0.95
8 15 0.56 1e+02 5.7 1.1 5 23 796 814 795 814 0.95
9 15 9.4e-05 0.017 17.6 2.3 3 23 821 842 820 842 0.97
10 15 0.045 8.4 9.2 0.1 2 23 858 878 857 878 0.96
11 15 0.00027 0.049 16.2 1.4 1 20 884 903 884 906 0.92
12 15 0.00037 0.068 15.8 0.2 1 23 914 936 914 936 0.99
13 15 0.0033 0.61 12.8 3.2 1 23 942 964 942 964 0.97
14 15 9.8e-07 0.00018 23.9 3.5 1 23 970 992 970 992 0.98
15 15 0.0022 0.4 13.3 7.0 1 23 998 1020 998 1021 0.96

Sequence Information

Coding Sequence
ATGGATTCAACAAACATAATTTGCCCTGTTTGTACTTTATATCTGAGGCCTGGTATTACTTTGAAGCAACATTTATCTTCACATCCCAAACAAAAAGTAATAGAAGCCCTGGTAAAGTTATCTGGAGGTGAAGAAACACAAAAGGTGCAAAATGTAGCTCCTCAGTCAGATCTAAGTGCTGCTGGCAGCTCGCAAGTTAATACAGCAATAGTTAATCAATCATGGAACCAAGCACCACATGGTCAACTAGGACCCCCACCTCCCATAAACCCTATACATGGAAACCATGTATTTATTTATCAACAAAGTATGAGTACAACCTCACCTCAACCGAATGTGCTAAATGTAAACCCATTGTCACAGCAATACGTTTATCCGACGGTTTTCAATCCTCAAATGATGCCATATGTTTATCAACAACAGCAAGTAATAATGTCCAGTAATTCTTTACCTCCACATATTAGAGCACTTCCTTTTGAATTACCTAGTACATCTCAATCAAATGCACCAGAGGAGACAGTTCAAAATGAGAGCGAAAATAATGAGCTGGAAGACAGCAGGATTGTCGAAGTTCAAGATAATAATGGAGAGTCTGGCCAACATGAAGGACCACTTATTAAAGATAGCGAATGTTTTGCTATCAAATCTTCTGATGAACCACCAACAATTAAAAAACAGGAAATTCTGGATGTGTCCAATGATGTGAAAACTAtggaagattttgaaaatgaacAACTGATTCTTAATGAAATACCATCTGAAGGATATAACAATGAAAACAATGGGGATTATGATCATGTCGATCATGAAGAGTGTATTGGGTCACCACAGTCTCGGTCAAATTCTGATTGGGGATTTCATTCAGATTTAAACAAGGCATGTCAAACTCAAATTACAACTAATACCTCACCTAGATCTCAGATTTTAGAAGATGAAGAAATTTTAAGGGAAAATCAAGATAATCATGAAGATCAGCCCGAGTATTTCTATATTAACCAACAGAATCAGGGATATATGAAGCAACAGAATGAAGAACAACAAAATATTATACCATATACTACAGTTAAGGTAAATGCAGACAACTATGAGCAATCTGAACCAATCTATACCTCGGCAAATATACTACATGGTGGTGATCAGTTAGATTTTGTTAATATGGATGATATTGTTATTATAAGTGATTTTTCTACCAACCAAGTTATTTCACAAGTGGAGAATTTTGATAATACTTCCCCAGATAGACCAGGAGTTTTAATGACTATCGGAGATATTTCAGATCAgccaaaaaatgattttattgaaCAGAGAGATCTGGAAGAAAGCATGTCAAGGGAAAGTTCACATGTGAACATAAGATCGGATGAAAGAATGCCAGCATGTGGTGAATTGTCTGGACAGGAGAGCATTGGAGGTGCTAGTGATATAACGTGGAATCGAATGCAGTACCAAGAAGGTAGTTCAGGAATGTCCCATTCTTATGATTTAATTGGTAGAGAAACTTGGGAAGCCTCAGATAGTGATAGTGTAGAAGTACCAACATTGCAAAGACGACTTCCAATGCAGTTGGATTACCAACAAAATGAATTTAACGATAACGAAAATGACACGCCTACCATTGTTAGCTACTCTGGGCCACCTTTAAATTTCAAATGCCCAACTTGTGGAGATGGTTTTTCTAGCTCAAAGGAAAGAAAAGAACATGAGATTGAAAAGCACCCAGAGAAAACCATTAAAACTAATATAATAGGGTCTGAGATTGGAAAAAGGAAAGTTAAAAAACTTGTGGTGAAGTTGAAATCAGACAAGACTGAGAGCGAAAATAATTTCGATAATGTATTTACTAATAAGTTAAAGTTGGAGAGTACAACCGAAGCACAAGTAAATGTGGTTGTTGACAATCAGATTAAAATGGatgaaattaatttagaattaaaagATTTGAAAACAGTCTGTCCAATTTGCGATTGTGTTGTTGAAAATGCTAAGGCTTTAAAAGTACATAAATTGGAGGTTCATAAGGAAAGTGCGGATGTACGCCATAAATGTTTGACATGTGGTGAAGCTTTTCCAAATGAGTATAAATACACAGAGCACCTTAAAATACATCCTCTGGAATGTAGGTTGTGTGGTAAGTTATTTTATAGACGTCAAAATATTCACTTACATATGAAAAGGCATCTTGGGCTGAAGCCTTATAAGTGTGAAATCTGTCAAAAATCTTTTGTAACTAAACAAAAACATGATGAACATAAAAATATTCACACAGGTGAGGCCCCTATTAAATGTAACTTGTGTGATGAAACATTTAGAAGACATTCAAATTTAGTACAGCACCGTAACCGACATCACTTTCAAATGAAAAAGAAAGTCAAAGATTATATCTGCCAATGTGGGGAAATTTTTCATTCTAAAAAAAAACTAGCATGGcataaagaaattcatgattcTAAACCGAAGGCCTGTACCCAATGCAGTGAAAAATTTGTCCATATGTCAAGTTTAACAAGGCATATGCGTCGTGCTCATAATGAAAAGTTTTTGCCACAGGTAGATAGAGACAATGAAAATGTGGAGTGTCCCATATGCAAAGGAACTTACTTAAGGTCTTCGCTTGAAGTACATATTCGAAATCATAGTGGACAGAGACCGTTCACTTGTTTGATTTGCAACAAAGATTTTACGACCAAATGGAATCTAAAATTACACAAGTGGACACATGCCAGTCGTACTTCAAAACCCTTCAAATGCACTCAGTGTAAGGGTGCATTCATTAGGGAAGCTGATTTTATAGCCCACATGAACTCTCATAAAAGTGTGCGTCCTTATACATGTAATTATTGTGGAGCTCAGTTTATTCGAAAGTATAACTGCTTAAGACATGTTAAAGAGCacgaaaataataaaacattcaGTTGTCAGGTTTGTGGAAAGTCTTTCCATAGATCATATTACTTAAAAGATCACATGCGAGTCCATAGTGGCATTCGGCCCTATTCGTGTCATATTTGTGGGAAAACCTCCACAACTAAATCTAATCACAATAAACATGTACAAATTCATCATGCTAGAGAACCAGTCagtacagaaaattaa
Protein Sequence
MDSTNIICPVCTLYLRPGITLKQHLSSHPKQKVIEALVKLSGGEETQKVQNVAPQSDLSAAGSSQVNTAIVNQSWNQAPHGQLGPPPPINPIHGNHVFIYQQSMSTTSPQPNVLNVNPLSQQYVYPTVFNPQMMPYVYQQQQVIMSSNSLPPHIRALPFELPSTSQSNAPEETVQNESENNELEDSRIVEVQDNNGESGQHEGPLIKDSECFAIKSSDEPPTIKKQEILDVSNDVKTMEDFENEQLILNEIPSEGYNNENNGDYDHVDHEECIGSPQSRSNSDWGFHSDLNKACQTQITTNTSPRSQILEDEEILRENQDNHEDQPEYFYINQQNQGYMKQQNEEQQNIIPYTTVKVNADNYEQSEPIYTSANILHGGDQLDFVNMDDIVIISDFSTNQVISQVENFDNTSPDRPGVLMTIGDISDQPKNDFIEQRDLEESMSRESSHVNIRSDERMPACGELSGQESIGGASDITWNRMQYQEGSSGMSHSYDLIGRETWEASDSDSVEVPTLQRRLPMQLDYQQNEFNDNENDTPTIVSYSGPPLNFKCPTCGDGFSSSKERKEHEIEKHPEKTIKTNIIGSEIGKRKVKKLVVKLKSDKTESENNFDNVFTNKLKLESTTEAQVNVVVDNQIKMDEINLELKDLKTVCPICDCVVENAKALKVHKLEVHKESADVRHKCLTCGEAFPNEYKYTEHLKIHPLECRLCGKLFYRRQNIHLHMKRHLGLKPYKCEICQKSFVTKQKHDEHKNIHTGEAPIKCNLCDETFRRHSNLVQHRNRHHFQMKKKVKDYICQCGEIFHSKKKLAWHKEIHDSKPKACTQCSEKFVHMSSLTRHMRRAHNEKFLPQVDRDNENVECPICKGTYLRSSLEVHIRNHSGQRPFTCLICNKDFTTKWNLKLHKWTHASRTSKPFKCTQCKGAFIREADFIAHMNSHKSVRPYTCNYCGAQFIRKYNCLRHVKEHENNKTFSCQVCGKSFHRSYYLKDHMRVHSGIRPYSCHICGKTSTTKSNHNKHVQIHHAREPVSTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01370122;
90% Identity
iTF_01370122;
80% Identity
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