Basic Information

Insect: Leptura quadrifasciata
Gene Symbol: Hr39
Assembly: GCA_963675555.1
Location: OY776681.1:18994084-19032806[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.21 8.5e+03 -2.0 4.6 52 98 202 249 99 318 0.54

2 3 3.5e-09 0.00014 23.6 0.0 1 65 388 453 388 490 0.78

3 3 4.5e-73 1.9e-68 234.0 0.2 205 408 519 717 498 717 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.21	8.5e+03	-2.0	4.6	52	98	202	249	99	318	0.54
2	3	3.5e-09	0.00014	23.6	0.0	1	65	388	453	388	490	0.78
3	3	4.5e-73	1.9e-68	234.0	0.2	205	408	519	717	498	717	0.96

Sequence Information

Coding Sequence: ATGGCCGCAGACATGAGGTCCCCCAACGTATCTGTTACTCCAATAAACATGGAGCCCTACCCACCCTCTGTCCTCTCTAACGGGGACCATCACCCCCCTAGCGAGCCACCCCAGAGAACAAGAAGCGCTCCCCATCCAGCAGCTCTAATTACAAATGGTACCACTGATATCTTGGATAGTTCCGATGCAGAAGTGGCCAGAATAGACTTTCATGCAGTAAATATGAGATCAAAGAAGAAAAGGGATGATCTACCGAGGCCTATGAGTTGGGAGGGTGAACTTTCGGATGGAGAGAGAGATGGCATGTGTGTGGATGAGGAAAATTCGGCACAGGTTCCCGAAAATCTTTCGCTATCGCAGTCCAAGCAATGCTCCCTGTCAGATTCAAAAGAGAGCCCCATTTTGCGATTGAAGCAGCCTCCCATGGGCAACTACTCCTTGCACAGCACACCGAGCAACTCACCGTTACTTAGCCAACGTCACCCTGTTACAGGTGTGCCCATCATAAGCCATAAGGATCTCATGCACAAGGCTCTGAATGTCCCTCCTACCCCTAGCCCCGATTCAGCGATCCACTCAGCGTACAGTGTTTTTAGTTCACCGAATCAAAGTCCCTTGACTCAGAGACATATTACTTTAACCCCAAATTTGAGTAGGAATAATAGTGACGCGTCGCATTCGAGCTGCTGTAGTTATAGTAGTGTCTCCGTTTCTGTGTCGCCCACGCAGCAGTTCTCCCCCACACACAGTCCCATACAGGGACGCCATATGCACAGTATTCATAGTAGCCCCTTACACCATAATATCCTTTATCGAAGCCTCCAAGAGGACCCCACCATACAGTACACCACCGAGCACGACGTTCTCGATGAACCTGAAGACAAAGCAGGTCTCCTACATACATCACTACCCGCCCAACCGGGCATATCCAGGCAGCAACTTATCAACAGCCCGTGCCCTATTTGTGGAGACAAAATATCCGGTTTCCATTATGGCATTTTCAGCTGTGAATCATGTAAAGGCTTCTTTAAGAGGACTGTGCAAAATAGGAAAAACTACGTGTGCCTGAGAGGTGCTCAGTGTCCAGTGACGGTCGCTACTAGGAAGAAGTGTCCAGCTTGTCGATTTGATAAATGTCTTCAATGCGGGATGAAACTGGAAGCAATTCGGGAAGACAGAACACGTGGGGGTCGATCAACATATCAGTGTTCATATTCGTTGCCACCGTCATTAACTAATCATGCTGAACTAAGGGCCAGCTCGACTGATTTAAGGCAAGGGATGGGAGAAACTCATCCTGGACTTACGGTAAAGTTAGAACCGCCAGATTCTGGAGTTTCACATCACAAGCGAAATACTTTACCAGGATCAAAAGGCGTCCCACCATTATTGCAAgaAATAATGGATGTGGAGCACCTATGGCACTACAACGAAATGGAGCTGAACAAATTGAGTACGGAAGGCCATTTGGGGAAAGAAGGTTCAAGCGGGGCTGTGCACAACCTCTCTACACATCCGTTACTAGCCGGTACGGCACTGGCTGGTTCGACGGATACTAACCCTGATTTTGTAGCAAATCTCTGCAATATAGCAGATCATAGACTTTATAAGATAGTGAAGTGGTGCAAGAGTCTCCCTTTGTTTAAAAACATATCGATCGATGATCAGATATGCTTGCTCATCAACTCGTGGTGCGAGCTCCTCTTATTCTCGTGTTGCTTTCGGTCCATGTCGTCTCCCGGGGAAATAAGGGTGTCGCTGGGGAAAAGCATAAACTTGGCGCAAGCCAGGGAAATGGGCATGCAAGCTTGTATAGAGAGAATGTTGAATTTCACAGAGCAGCTTAGGAGGCTTAGAGTAGATCAATACGAATACATCGCCATGAAGGTCATCGTCCTCCTTACGTCGGATACTTCAGAACTTCGGGAAGCCGAAAAAGTGAGGGTCTCGCAAGAAAAAGCTTTAAAAGCCTTACAGGATTACACCTTGTCACATTACCCCGAAAGTCCTGCCAAATTTGGGGAACTACTCCTGCGTATTCCTGAGTTACAACGAACTTGCCAGGTCGGAAAAGAGATGCTAACGATTAAATCGAAGGACGGCGACGGACCTAGCTTCAACCTCCTCATGGAGCTCCTAAGAGGGGACCACTGA
Protein Sequence: MAADMRSPNVSVTPINMEPYPPSVLSNGDHHPPSEPPQRTRSAPHPAALITNGTTDILDSSDAEVARIDFHAVNMRSKKKRDDLPRPMSWEGELSDGERDGMCVDEENSAQVPENLSLSQSKQCSLSDSKESPILRLKQPPMGNYSLHSTPSNSPLLSQRHPVTGVPIISHKDLMHKALNVPPTPSPDSAIHSAYSVFSSPNQSPLTQRHITLTPNLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHMHSIHSSPLHHNILYRSLQEDPTIQYTTEHDVLDEPEDKAGLLHTSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAQCPVTVATRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTNHAELRASSTDLRQGMGETHPGLTVKLEPPDSGVSHHKRNTLPGSKGVPPLLQEIMDVEHLWHYNEMELNKLSTEGHLGKEGSSGAVHNLSTHPLLAGTALAGSTDTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSSPGEIRVSLGKSINLAQAREMGMQACIERMLNFTEQLRRLRVDQYEYIAMKVIVLLTSDTSELREAEKVRVSQEKALKALQDYTLSHYPESPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00753059;
90% Identity: iTF_01014531;
80% Identity: iTF_00886055;