Basic Information

Insect: Leptothorax acervorum
Gene Symbol: fru
Assembly: GCA_035220615.1
Location: JASTWQ010000038.1:697805-701806[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.7e-26 2.2e-23 83.9 0.2 3 101 67 161 65 169 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.7e-26	2.2e-23	83.9	0.2	3	101	67	161	65	169	0.92

Sequence Information

Coding Sequence: ATGCACGAAGGtcaaaagtattttaaaaataaggcCGTAGGCATTGGCAGATTGGTATGGCAGTGGACGTTAAGGGTCGGGTGGCGTTGTAATGGCAAAAAGTTTGCGAGAGGGTCGGGATTGGAGATAGACAAGATGGACCAGCAGTATTGTCTACGGTGGAACAATCATCCAGCCAACCTCACAGACGTTCTCAGCTCGCTGCTCGCCAGAGAGGCACTCTGTGACGTGACCCTGGCCTGTGTCGGAGAGACCTTCAAGGCGCACCAGACCATACTCTCCGCATGTAGCCCGTATTTCGAGAGCATTTTCCTGCAGAACACCCACCCCCATCCAATCATATTCCTCAAGGATGTCAATGACACGGAAATGAAGGCGTTGCTGCACTTTATGTATAAGGGCGAAGTCAATGTTAGCCAGCATCTCCTACCGATGTTCCTTAAAACAGCGGAGGCATTGCAGATCAGAGGCCTCACCGATAATAGTGTAAATAACAAAACGGAGGACAAGTGTCCGTCACCGGATCCAGAAACGCAAACTGGAGTCAGACATAGCGACTCGCCTAACCTCCAGTCTCATCAtgagaagaggaaaagaaagaattcAGGCAGCTACGACGTTTCTCTTTCTGGCCCACCTAGCGAAAGATTCTTGTCCGATTCTCAGACATCCTCGCAGTGTAGTTACAAATCAAGTCCTCCTGTGATTCCAAAGTTAAATAATGCCCTGGGAGTAGAGATGGAAGATGGTGGTCGACCCATGTCCCCTGCTTCACAACCGCAGGCTCCTATTAAACAAGAGGTGGATCACCACTTGCCCGACTTCCATGACAATATTTCCCTCCCCACTGGTATGGAGTGGGAGGTTCAGAGAGATGGGAAGAGTGACGAAACTATGGATGTACAGAACATGACTTCAAATCGTCCAGATTCGGCTGTGGTGCAAGTTTCTCGCGAAAGTGCCATCTTGGCTGGAGGTTCTCTCTATGTCGATATGTCGGGAATTGCGTCTGAACTCCCCGGAAATTCGCGTAATCCGCTAAGTCAAGCCGTATCCATGAACTCGCACCATCCGTATAAAAGCAATAGCATTGATCAAACTCAGTCTTACGAATCGTTGTCCCAATATAATCCGAATGTTAAACCACTTGAAAGTGATATGCATAGATCGATACAAATAAATCAGGAATCAGGAATGTCCGTAATTCAGTCGACAATGTGCGCAAACTTGCAGCGTCCTACTTCGCAAAGTAGAAAGGCTGGTAGATTTAAACCCGGGTGGTTAGACACGTATCCTTGGCTACAATACGACGAACGATCGAATCTTATGTTTTGCAAATACTGTAGAAAGTGGAGCGAATCCATACCAGAAATTCGCACTTCGTTTGCTGCGGGAAACGGCAATTTTAGACTCGAAATCGTGAACCACCATGATAAATGTAAAGCACATAATCTGTGCGTGACAAAAGAAAGCGAAGCAAGAAAAAGTTACGCTTATACGACAAAAACATGCTAG
Protein Sequence: MHEGQKYFKNKAVGIGRLVWQWTLRVGWRCNGKKFARGSGLEIDKMDQQYCLRWNNHPANLTDVLSSLLAREALCDVTLACVGETFKAHQTILSACSPYFESIFLQNTHPHPIIFLKDVNDTEMKALLHFMYKGEVNVSQHLLPMFLKTAEALQIRGLTDNSVNNKTEDKCPSPDPETQTGVRHSDSPNLQSHHEKRKRKNSGSYDVSLSGPPSERFLSDSQTSSQCSYKSSPPVIPKLNNALGVEMEDGGRPMSPASQPQAPIKQEVDHHLPDFHDNISLPTGMEWEVQRDGKSDETMDVQNMTSNRPDSAVVQVSRESAILAGGSLYVDMSGIASELPGNSRNPLSQAVSMNSHHPYKSNSIDQTQSYESLSQYNPNVKPLESDMHRSIQINQESGMSVIQSTMCANLQRPTSQSRKAGRFKPGWLDTYPWLQYDERSNLMFCKYCRKWSESIPEIRTSFAAGNGNFRLEIVNHHDKCKAHNLCVTKESEARKSYAYTTKTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01409316;
90% Identity: iTF_00765772; iTF_01523489; iTF_00898887; iTF_01520391; iTF_01407509; iTF_01409316; iTF_01477720; iTF_01421659; iTF_01423772; iTF_01423029; iTF_01477020; iTF_00181405; iTF_00182709; iTF_01354718;
80% Identity: -