Basic Information

Insect: Leptopterna dolabrata
Gene Symbol: ham
Assembly: GCA_954871275.1
Location: OX940983.1:6749469-6773536[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.063 20 8.0 0.0 2 23 78 100 78 100 0.95

2 9 0.027 8.7 9.1 1.8 1 23 107 130 107 130 0.97

3 9 4.2e-08 1.3e-05 27.4 0.8 1 23 136 158 136 159 0.96

4 9 4.6e-06 0.0015 21.0 2.6 1 23 165 187 165 187 0.95

5 9 2.8e-05 0.0089 18.5 5.0 1 23 193 215 193 215 0.99

6 9 0.0027 0.86 12.2 0.7 2 21 223 242 222 243 0.95

7 9 9.6e-09 3e-06 29.4 0.7 1 23 630 652 630 652 0.98

8 9 3.5e-07 0.00011 24.5 1.7 1 23 658 681 658 681 0.97

9 9 3.8e-06 0.0012 21.2 3.3 1 23 687 709 687 709 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.063	20	8.0	0.0	2	23	78	100	78	100	0.95
2	9	0.027	8.7	9.1	1.8	1	23	107	130	107	130	0.97
3	9	4.2e-08	1.3e-05	27.4	0.8	1	23	136	158	136	159	0.96
4	9	4.6e-06	0.0015	21.0	2.6	1	23	165	187	165	187	0.95
5	9	2.8e-05	0.0089	18.5	5.0	1	23	193	215	193	215	0.99
6	9	0.0027	0.86	12.2	0.7	2	21	223	242	222	243	0.95
7	9	9.6e-09	3e-06	29.4	0.7	1	23	630	652	630	652	0.98
8	9	3.5e-07	0.00011	24.5	1.7	1	23	658	681	658	681	0.97
9	9	3.8e-06	0.0012	21.2	3.3	1	23	687	709	687	709	0.98

Sequence Information

Coding Sequence: ATGTTTTCGTACGAGGCCCTGTTGCTCTCACTTGATCGAGGCTCTGATTCGATAGCGATCGCACGAAGCGGCGTCCCCTTCTTCAATAGCGTGTACATCATCCGTTTATCAGATTGTGATATCAGATCCCTGGATCACACATCATTTAAGCCGTCCCTGACGACCATCAGTATTTCCCATGTTTACCTCCAGCCCAGCGGTGGTGAAGAGGAGGACGAGGAAGATATAGCCCGGTGCCCAGTTTGTGAATCTACATTCCCTGACGTTGATCTGTTGGACGATCATTTGATCAGCGGGCACAGATACGCGGCGAACCAGTACCGCTGCGATAAGTGCAGCCGCACTTACGCTTGGCGCCCGTCCCTGCTCCATCATCAGGCCACCAAGCACGGTGAAATCCGACGCTACCCTTGCGAGAACTGTCCCAAACTCTTTTCCGACCCTTCCAACCTACAGCGTCATATCAGatcgcaccACGTAGGAGCTCGATCTCACGCTTGCACGGAGTGTGGGAAAACATTCGCGACGAGTAGCGGCCTGAAGCAACACACGCATATCCACTCGAGCGTCAAGCCCTTCCAATGTGAAGTCTGCTTCAAGGCGTATACACAGTTTTCAAACCTTTGCCGACATAAGCGGATGCACGCTGACTGCCGGATGCAAATCAAGTGCGCCAAGTGCAACCAGACGTTCTCTACTGGCACTTCACTAGCTAAACATAAAAGATTCTGTGACTCTACGAACCCGTCACCAGCTATGTCTCATTCGCACCACGGCCCCCATCCGTCGCCAAATCCATTCATGCTGTACCCCAGGCCTGGCATGCCTTTCTACCACCCGGGTCTCCTGCCGACCTATGGAGGCGCCCTGACCGCTGGCTCTCCCTTGTTCAATCCTCAGGCTTCCTTCTTTGGATCGCCCCACGTCCCCTTTCCCATCAACCCAAACCACGCTCAGCTCTCTAAAGAAGAAATGGAAGAAAAGAGATCTAGAAGCCCTTCTCCTTCAAGCAGCGCTCTTTCCCCAGTGGAGCCAGTCACTCCATCAATGAATTCTATGATTCATACAAACAAAGTCTCACCACCTGCTGCTGAAGAGGCTGCCTCTAACGAGCGTCCAAGCCCAGCTAGACCACCAACTTCGGCCAAAGTTCAACTTGATCAACCTCAGGACCTCTCGTGCAATGACGGTATGAGATCGCCATTGTCATCGAGATGTCAATCTCCGAGTGATCAACCGTTGGACTTGCGGATTGGTGGGAAGCGCAGAAGGAGCCCCAGTCCCGAGCATTCAAAGGAAGACAGATCCGAAGATTGGAGGGAGGCTGAAAATCACAGTCCGCCTTGCAAAAAAGGAAGTTTTGTGGAGAACGTGAAGAAAGAGAAGgaagaggatgatgatgatgacaaTAAGTCTGATATTAAAGTCGAAGTTGAGGAAGACGAGAAGGAAATTCGAAAAGAGCCCGCTGAAAGGGAGAGCAGCCCCAAGCTGAAGCCTGCTGATTCTCCAGCTGCCTCCTTCAACAACTCGACTGGTTCATCGAACAACTCCGTATGCTCGGACATACCATCGCCCCCCGTTTATCCCCGGCCAGTGCATCCGATGTTTCTGGAGAGCCTGTACAGCCATTCTCAGGCTTCTTCGCCTTTCCATCCTCCTCCAAATCCAGTATTCACGTCACCATCAGCCGCCTCAGCAGCCTCGAAGTTCTCCAGGAGCTTTCCGGCGTTTTTGGGAGCGATCGGCGGACCGACCTACGACCTCGCTTCGCGTGGGCTCCAAAGTCTCCATCACCACCTGAACGGTCGGGGTCCCCCTCCGAAAACGTTCCAGGAAGTCCTTGGAGGACAGAGCGCTGCCCAGGGTGCCCGAGTCAAGGACAGATACGCTTGCAAATTCTGCGGAAAAGTATTCCCAAGGAGCGCTAACCTTACTCGACATCTCAGAACACATACTGGAGAACAGCCCTACAAATGTAAATACTGCGAAAGATCATTTTCGATATCTTCCAACCTCCAAAGACACGTCAGAAACATTCACAACAAAGAAAAACCGTTTAGGTGCCCACTTTGTGACCGCTGTTTTGGACAGCAAACCAATTTGGATCGCCACCTAAAGAAGCACGAAGGAGAGGATGGTCAACCGGCCGCAGCAGACTCACCGAGCTCGGACAACGAGGACCCGGTGACGGGGACGGCGAACCGTGAGGACGCCTATTTCGACGAGATCCGCTCGTTCATGGGAAAAGTCGCCTCGTACAACAACAACCTGAGCCACCACGGTCTCGACAACAACAACTTCGGAGCCGTTCCGGATCCCAAGTACTTCGGGTTTCCTCCGCATCCGAACTTCGGCGGTCGCGACAGCTCTCCGGTCGCCTCCAGGGTGACGAGCCCTCCGACGAAGTCCAACATGTCGGAGAGAACGAAGGACCGGCCGTCGACCCCGTCCACGTCGTCTTCCCCTTCGCTGTCCCCCAGAAGAAGTCCACTGACTGCGACTCCAACGGCAGACAAACGGCAGAATCTAAACAATAACAACTCCCCAGCGTTTCAAGTAGCTTCGTAA
Protein Sequence: MFSYEALLLSLDRGSDSIAIARSGVPFFNSVYIIRLSDCDIRSLDHTSFKPSLTTISISHVYLQPSGGEEEDEEDIARCPVCESTFPDVDLLDDHLISGHRYAANQYRCDKCSRTYAWRPSLLHHQATKHGEIRRYPCENCPKLFSDPSNLQRHIRSHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCAKCNQTFSTGTSLAKHKRFCDSTNPSPAMSHSHHGPHPSPNPFMLYPRPGMPFYHPGLLPTYGGALTAGSPLFNPQASFFGSPHVPFPINPNHAQLSKEEMEEKRSRSPSPSSSALSPVEPVTPSMNSMIHTNKVSPPAAEEAASNERPSPARPPTSAKVQLDQPQDLSCNDGMRSPLSSRCQSPSDQPLDLRIGGKRRRSPSPEHSKEDRSEDWREAENHSPPCKKGSFVENVKKEKEEDDDDDNKSDIKVEVEEDEKEIRKEPAERESSPKLKPADSPAASFNNSTGSSNNSVCSDIPSPPVYPRPVHPMFLESLYSHSQASSPFHPPPNPVFTSPSAASAASKFSRSFPAFLGAIGGPTYDLASRGLQSLHHHLNGRGPPPKTFQEVLGGQSAAQGARVKDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKEKPFRCPLCDRCFGQQTNLDRHLKKHEGEDGQPAAADSPSSDNEDPVTGTANREDAYFDEIRSFMGKVASYNNNLSHHGLDNNNFGAVPDPKYFGFPPHPNFGGRDSSPVASRVTSPPTKSNMSERTKDRPSTPSTSSSPSLSPRRSPLTATPTADKRQNLNNNNSPAFQVAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00930625;
90% Identity: iTF_01365791;
80% Identity: -