Basic Information

Insect: Leptopterna dolabrata
Gene Symbol: -
Assembly: GCA_954871275.1
Location: OX940981.1:19169453-19194489[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 8.6e-12 9.9e-08 33.6 0.0 4 71 169 238 167 241 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	8.6e-12	9.9e-08	33.6	0.0	4	71	169	238	167	241	0.86

Sequence Information

Coding Sequence: ATGAGCGAAGCTTCTAGTGATCCGAAAGCTGAAGCTATGGAAGTGAATGAAGGCGACATTATCAACGGATTGAGTGATACGATGGATGTTGATGAGAGCTCTACTAACAAATCAGCGGATGAATCAATAAAGCCAGGTAAAATTACCGAAGTCAGTCGGAAATCAAGCTCTTCCGTATCTTCGGAAATATCCGCTACCAAGGATGCCGATAAACAAGCTGAGGCCAAAGATGGCAAACCCGACTCCAGCAGCGACGATGAAGATTTTTTGGGATTCTCTTTACCGGTCGATGGTTCAGCTCGAGAAAGATTCCTTCAGTTTCTGAAGAAAGAAAACGAACTTAGAACAACTTCGCAAGTTGATGACGATGTGCGAAGTCTGTCTGACATGATGAGCATTGAAAATGTGGACTCTGACTCTAACACAGATAGTATTGCTGCTTCTGGGAAGATCGCTGAAACAAAACCTGTACCTTTAAGGAAGAGTTCATTAATTGATATTAACAAAGAAGAATTTAAGAAGCCCTTCGATTTCGGTTGGGTTCGTGAAGTTGTTATTCGTCCTTCTTCGTCAAATCCTTTGGAGCGAAGGAAAGGCACTAGTGCTGATGTCTATTATATAACTCCGTCTGGGAAAAAGTTGCGGTCGATCCGAGAGGTTGCTGATCATTTATCTGGGGGAGATCTGACAATCGCGAATTTCACTTTTGCCAGAGATTCCATTGGAATTAATGATCCGAAGAAAGAAATCGTCCGGCCAGCTGCCGAAACTCGATCGCTCAGGAGTGACGACTCATCGACACCTCAAACGAAAAAAGCTACTCCAACAGTCAAGTCTAAACCTAAAGGCACTACCGAAGTCCAAGGAAAAGCCTCAACCCCTAAAGTTGCTTTCAAGTTTGCCAGTAAAAAGTTGCCTACAGGGAAGAAACCTGATAAAGCACGAAAATCGATAGGTGGTACGGAAGTTGATGATGATTCATCAGAAGACACTGACTGGGATATGGTTCAGAAAAACCCCACGCGAGAAGTGTGCTCGATCGAGTGCCGGCTGGCTATGGGACTCATCCCAACTCTCCAGTGCGTCAGCTGCCTATGCCTCTACCATCCAGAATGCGTCGGTGTTCAACAAGATAAACTCAGCTCTTCTAAACCATATAATTGCAAGAACTGTCAGGGAATAAGTGGTCAGCAGTCGAGCAATCCCAAAACCAATAACGTCCCACCACCACCCGCCCTGATTCCTCTTAGCCCTCAAAACACTTCGGGTTTCCCTAGAAAATCCATTTCAAAAACTGAACCCAAAACAAACCCTAGGCAAAACATTGTCGGCACCGTCACCACTTGGCTCCCCTCATCATCCAGCATTCAGGTCTCCCAGAGTTCCCCCACTCCCAAAACCTCCACTACGTCTACCACTATGTCTGTGACGCCCACATCCTCGACGAAATCCTCGGCGTCCGAAGGGCCTCACCAGGGACTCCTGGAAATCGGAGGCAATGCATTTGTTGTCGTACCCCGTCACAACGTCGTTAATGTTAGCAACCAGACGACGAGCGCTGCCCCAGCTGTGGCCGCTACTGCCAACAACGCCAATCCTTCTCAGACTCAAACAAATGGGATATTGTTGGTCCCTCTCTCTGTTCAACCTCCTGACTCAACATTGGCAGAAACTGCTTCCGTTTCGAACCCCATTAGGACCGTCAATCCTGGAGTTTTTGCTGCTGGTACTGCAACAAATCCCGAGACCAACGGTTTGAAACGAATTAGCGACTCATCTGTAGATGACGATGCACCTCCCGCCAAAGTCAGTGTTAAAGTGAAGGAAGTACCGCCGAACTACTTCCCCAATAACTTCTTCTCGATGTCCAATGCCGTCACGATGAGCATGCACTGTTTCTTCCAGTATTTGAAAGTCCACGAACTACTTAGAGCGACGCAAGTTAATAAAACGTGGCACTTCATCGCCACACATCAGTCCTTGTGGGAAACTGTGAGGATGAAGAACTCCAAAGTACGGGACTTCGAAGGTTTTGGCAACGCATTGCGAAAGTACAACACGAAGAGTTTAGACTTGAGGAAAATGATAACGCCGGAGTCGGCTGAAGCTACCACCGAAATGTGGTCCAGACTTGCTTCCGCCATCAGTACCCTTCCGAATTTGAGAAGAGTTGATTTTGGAAGATGCGCACCGAGTGCTATAGAAGTCGTTGCAGCTGCCTGCTCCCATCTCGAATCGATCACCTCATTATCAATTAGGGGACCCGAGCTGAACTTGACGCCTATCGCAAACTGCCACAACCTCGTCGAATTGAAACTTAAAAGTTTTGGTGGAATAGACGTCAAGCATCTTTCGTTGCTGAAACAGTTGACCAACCTTAAATCTTTGTATTTAACGTCCGTGAAAAATTTGGAAGGGATTGACCAGGCACTCTCGGAAAGCCTGGAGAACTTGGAGCTCGGGGAGTGTGTCAAACTGACAGAAAAGTTCGCTGTCAGCGCCCTCCCAAAACTGGTGAACCTCAAGAGGTTGAGGTTAGAGAGGGGCGGCACAGGTTGCCCGACGCTCCCCATCCTCCAAACCATCGCAAACCTCCCTAATCTTACGCAGCTTGAGCTCATCAACTTTGACATCAAACCCGGTTTCGACAAGGCGCTATCCAAGTGCACGAATATCAAAATCCTTTTGATAATTCCGACCTACGTGACGCAGTCTGCCACAACGAATCATGTGGTGATGGGAGGCGTGAGCAAACTTAGCGCCAGCCTGCAGTACTTCGTCTGGGGTCTCACCTTGGAGCTCCTGAGGGTCACTGACCTCTTCATAGACCAAGTTGAAGGTGGAAAGTCCAAGTCGGGTGGAGCCCCTGGGAAAAAAGTTGGGGCAGGTGACAGCATACCTATTTTAAAACCTATCAGCGACGAAGGTTTGGACTCCAGCAGGGAAGGCAGCACGTCCCAAGTCGACATCTTGGGCCTCCCCAAACTCCAGCGCGTCCTCTCCACCCTCTTGCCGCAAACTAAGATAAAGATTCTCAAGATCCCCGTCAGCGCAACATGGAGGCAAACCGTAACAGACATACCAGTTTGA
Protein Sequence: MSEASSDPKAEAMEVNEGDIINGLSDTMDVDESSTNKSADESIKPGKITEVSRKSSSSVSSEISATKDADKQAEAKDGKPDSSSDDEDFLGFSLPVDGSARERFLQFLKKENELRTTSQVDDDVRSLSDMMSIENVDSDSNTDSIAASGKIAETKPVPLRKSSLIDINKEEFKKPFDFGWVREVVIRPSSSNPLERRKGTSADVYYITPSGKKLRSIREVADHLSGGDLTIANFTFARDSIGINDPKKEIVRPAAETRSLRSDDSSTPQTKKATPTVKSKPKGTTEVQGKASTPKVAFKFASKKLPTGKKPDKARKSIGGTEVDDDSSEDTDWDMVQKNPTREVCSIECRLAMGLIPTLQCVSCLCLYHPECVGVQQDKLSSSKPYNCKNCQGISGQQSSNPKTNNVPPPPALIPLSPQNTSGFPRKSISKTEPKTNPRQNIVGTVTTWLPSSSSIQVSQSSPTPKTSTTSTTMSVTPTSSTKSSASEGPHQGLLEIGGNAFVVVPRHNVVNVSNQTTSAAPAVAATANNANPSQTQTNGILLVPLSVQPPDSTLAETASVSNPIRTVNPGVFAAGTATNPETNGLKRISDSSVDDDAPPAKVSVKVKEVPPNYFPNNFFSMSNAVTMSMHCFFQYLKVHELLRATQVNKTWHFIATHQSLWETVRMKNSKVRDFEGFGNALRKYNTKSLDLRKMITPESAEATTEMWSRLASAISTLPNLRRVDFGRCAPSAIEVVAAACSHLESITSLSIRGPELNLTPIANCHNLVELKLKSFGGIDVKHLSLLKQLTNLKSLYLTSVKNLEGIDQALSESLENLELGECVKLTEKFAVSALPKLVNLKRLRLERGGTGCPTLPILQTIANLPNLTQLELINFDIKPGFDKALSKCTNIKILLIIPTYVTQSATTNHVVMGGVSKLSASLQYFVWGLTLELLRVTDLFIDQVEGGKSKSGGAPGKKVGAGDSIPILKPISDEGLDSSREGSTSQVDILGLPKLQRVLSTLLPQTKIKILKIPVSATWRQTVTDIPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00145591;
90% Identity: -
80% Identity: -