Basic Information

Insect: Leptopterna dolabrata
Gene Symbol: Baz2b_1
Assembly: GCA_954871275.1
Location: OX940983.1:5884234-5945420[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.3e-20 1.5e-16 61.8 0.0 7 74 499 564 495 567 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.3e-20	1.5e-16	61.8	0.0	7	74	499	564	495	567	0.93

Sequence Information

Coding Sequence: ATGGAGAAAGAGAATGCATCGGCGGCTTCAGAAAGGGAGAAAGACCGACAAGCGCCGAGCCTTCTCGACCCAGCCGCCCTATTCGGAGCGTTCTGGCCACGTCCTGACGGAAGTAATGCCTCCGCTGCCAATGCCAACCCGTTGTTCAGTGCCTACACGGGAGCCTATGGTGGGCTACTGGGCCGGGCGGGGACCCCTGGGGCCGGGTTTCCCGCCGGAGCCAACCCCTACGGGACACTGTCCGTAGCCGCGTCCCAGGCGTCCGCTCTTGGAATCAACCCCGCCAGTATGGGAGCGTGGTGGAGCATGGCTCAACAACTAGCTGCTCAGGACTATCTTGCTCAGCTGCAATTCGCAAACATGTTACCACCTTACCCAATGATTCCCACGCCCCCACACTTGAGTTCCAACAAGACCAGCCATTCCAAGAACTCATCGTCCTCTTCTTCTTCCACAACGCCCTCTGCTACCGTATCTGTGCCTACGACCTCTCAACCAACGTCAACCAGTGACAGTTTGGTGGGTGTTAGATTGCCCCCGGACACGGAGATCATCAAGTACACGTCGTCGATGGTGGGACCCAAGATACCTGGGACGACCAACAGAGGGCGGAAGAAGACCATCTCGCTGGACCACCCTCACCTGAACTCCCTCAAACACAGGAGCCATAGCAACGAGCTTCCCAAAACACCCTATGTTGGTCTGGACCTAAGTGGCAAGAGCAAAGATGCGGCATCCGTCGAAGATTCTTTCTATCGCTATGGTTCGGATAAATCGGATAGGCTGGATGCTGTCAAGTCGGGCCAAACGAACGGAAGAACTTCGCCACCTGGTCCTGCCGATGATGGTCCGTTGAATCTGTCCCTGAAACCCGACGTTTCGACTAACCACAATAACAACAATTCTGCGCTCCAGTCCTTATCAGCCCTCTCCCAGACTCTCGGTCAATCCGAAAGAGTGGACCGAAGGAAACCTGGTCCTAAACCAAGAAGAGTGCCTCCATTCGCGCCATCAGATTCTTCACATCCATCGAGTGGTAGTGAAGAAAATGATTCAGTAATACTCCCCCACAAGGATGGTAGGCCGAGAAATCTTGGGAGGGGGATCTCCAAACCAAAGAAAAACACCGTAGCCTCACTTCTAGCGCAGAGCAGGGCGCTGGGTATCAAACCTGGCCTCGAGGTGAGCCAGCTAGCAGCATTGGCCCGGGCTACCTCCAACTTCGAGAAGGACAAAGAGGAGAGTAGTATATCCAGCTCACCCAACTCTCTGCATGATCAGCTCCAACCACTGCCACTGAACCTGAATCGTAGCTTCGATGACCACAAGCACACTAGTTACGACGGTATATCCGAAGACAGCCACTCGGATATGACGGACTCCAGTTCTGACAGCGATGGCGACAGCCATAGCAGGAAGAGGGACCGTGACTCCATGTCGAATGATGGTGGACCTGGAGGTAAAAGGCGAAAAGTGGTGATAGACGAAGGGAAGCTGAGGGAGGCTTTAGCCAAAGGATGGAAGCGGGAAACGTACATCACGAGCGTGGGCAGAGCAGGCGTCAAGGGCGAGGTCGTTTACACGTCGCCCTGCGGCCGGACCTTTCGACATTTCAGCGACCTAGTCAGATTTTTAGATAAGCAAGGATCAGATCTCACGAGAGAGTATTTTTCGTTCAGTTGTCGTATTCTACTGGGCGATTACATCGAATCGGAACAGGGTAAAGAACCAATTAGACTGAGTGAAGGGACGCTAGCACTTAAACTCCAAGAAATGGTGGCCCAACACAgGGCTGCTCTGGATCTCAACAAGCAGGAAAGAGATAGGATGGCTCTGGCTGCTAAAGAGGCGAAGAGGTTGGCACGTGAGGAGGCGGCTAAACAGAAAGAACAATTAAGGCTCCTAAAAGAACAAGAGCGAAATGAGAGGCAGGAACAAGCCCGGAAAGAACGGGAACAACGAAACCAACAACTCCTCGAGGGTCGAAAGCGGCTTGCTTTCACAAGTGaagaaaaatggagaataaTTAGGGAGATCGAATCGGGGAAAAGCAAATCCGACGTTAGCCGAGAATTGGGTCTAGCTAATTCAACAGTGGCGACAATTTGGAAACAAAGGGGCAACGTCATGCCGACCCCTGGAGCTAGCTCGGCTCGGAAGAAAAAGCAAGAGGAGTTGGAGCGTCAACGGATAGAAGGCCAACAACGTAAACAGCAGGAGAGAGAAATGAAAAGACAGCAAGCAGCCATAATCAAAGAACAGGAGCGGGAAAGGCGCCGCCAGCATATGGCTCTAGTCAAAGCGCTTGAGGTCCGTAAGCGAatggaagagagagagaagaaacGACTGGAACAGCGAGCAGAGAAATTGGCGACGAGAGAGAAGAGGATAGAGCAACGAAAAGTGGAAGTTGAACTCCTCCGGGAACTGAGGAAGCCCGTCGAAGACATGGAGCTATCAGACCCGAAACCTTTACCAGAGTTACCTcggataccaggcctgaaactCACAGGTCAAGCTTTTGCTGACACCCTCATGGTTCATGAATTCCTCAGAAACTTCGGTGAAACCTTAGGCTTCGACATGGAATCTCTCCCCACTCTGAATTCGCTTCAAGAGGCTCTGCTGAACGAGAGTGAAGAAGCGGAAGAGGAGCTTCTGTCTGTGATAACTCAGCTTGTGATCTGCGGGATTGAAGACCCCGGTATCCCCCAACCCGCCCGACACACGACTCTCCTCAACCACAGCTTGAGGGCAGCTGACATAACTCACAGCAGCCTAAGTGAAATCCTTCGGATATACCTATACGCCAATGCTACAGGCGAGGTCAAAGCAACTACAGGCGTGCATTTCGAAAGAGAAAAAGAGAAGAAGGTGACTGAACACCATAACAAcatggatgacacggcggacgaaACGACGGGTAAAAACTCCGCGTTTTTCTCGCTTCTCAAGGAGAACCAAACGTATAAAATGTCCGAGTGGTTGAAGAAGAGGCCATTCCTTTCCCTCAACCCAACGAAGAAAGCCGCCATTCTGGCCTTCCTGTGCCACGAGCTTCTCCAGAACAAAGCGGTCATCCGGCAGATCGACTCGGCCATCGATACGGTTGCCCAACTCAAAAGGGAGCGGTGGCCGCTCGAAGCCAACTTGAGAAAGTTAAAGCACATCCAGGCCAGGAGAAACAAGGCCATGGGCGTCCAGTGCACAAAGGACGGCGAGGCGCAGGCGGACGATGAAGCGGAAGTTGAAAGTTGCAATGAAAGCGACATCACCCAGCCGGAAGAGGACGAGTTGGCAAAGATCAATATTGGTGAGACGCTGGCAGTCGTGAGCAAGCAGGCCGAAGTTAATACCAAAGCATTAGCAGATTACTCCGGTCAGCTGAGGGCAACCTGTCTTGGTCAAGATCGTTACTGTCGCCGATATTGGTGCCTAAGTACAGGAATCTACGTCGAAGGGGTGGAGTCTGCTGATCCTGAGATCTTCGCTGCCCCTGATCCCGAGCCCGTGGAAGAGGAACAGCTTCCGAGGAAGGTCGAGGTGAAGGATGAAGGTACCAGCGTCATGGAAATCGAAGAACAGCCTCATCTGCCGCCTCCTGCGAAAACTCCGGAGACCAACGGAACGCTGGACAGCCCTGAGCCTCCTGTCATTAAAGCTGAGATGCGGGATAGCTACGTCCAAGTCAAAGATGACGGTCAACAAACCGAACTTCCACTGAAGGATGACAGCCAACAGACGGAACTGATGCTGAAAGATTTCTCCACGCCTATCAAAGAGGAAGACAGCAAGGACGCCATGTCTGAGAAGTCTCTCACCCCCAAGTCCCTCCAGTTCGAGAGATTAGGAGAGTGTATGGAGAAAGAGTCGAATGCGGTGAACGGTTGTATTTCCTTGAACAGCAGCCACCATGAAGAGCATGTTCAGTGGTTCAGCATTCTGCCCAAAGATCCTTGCGATTCCACAAGTATCACCAATTCCCAGCCTGGCTACCGATGCTGGGCGGAGACAGCCGGAGAATTAAGGATCCCACAGCCCGGCATGTACTCAGGGTCTCCTTCCCCCTGCCCATCACCTCTACCGCTTCCCCTGTCGGCTGAAGAGGCTGCACTTCTCGAGCAGTGCAGGTTGCACGGATTGCCCAAGCCCGGAAGGCCGAAACCCATACCTGCTGATTTCAAGAAAAGTTGGTGGAAGATAACCGAAGACACCATGAAAATCATCCTTTCCAAGTTAGAGCCCAGAGGTGTGAGGGAACGAGAGTTCTTGGCCAACATCACCCGGTTACGAACTGACCACACTTGGGAATCGACGTTGAAGGCCAGCACGAGCGGGGACCCTAACAAAGCCCGATTCAAGACGATTGAGGGTGAAGAGGAGATTGTAGTCCCGTCGCCTGACGGTCCTCTAGATTGGGACGAGGAAACTGCTCTGAGGATAGATCTAGCTGCACTCGTAGCCGTTGAAGCGCTCGAAGAAAAGGTTGCTTCTGCAAGTATGCAGCTCAAGGGTTGGAAAATGCCGAGCAAGGTTACTACCTGTGATATCCCATTTAAACCTGCTTGCGTGGCCTCTGACCCTTCAGTGAACCCAATCGCAGTTGCTAAAGAAAGGCTAAGTAACCTTTTTGAAAACATCGAGAAGAGATACCTCAAACCACCACTTGGCACTAACATGGGCGATCTGAAACTGAACCAAGCTGCCAACAACACTGCCTCGACCGACGACTCCGACGGCGGCAACCGCGAGTGCAAAGGTCTCGTCGTCTGGAAAGAAGCTCTCCACAAGTCCCAAACGGCTGCCCAACTCTCGATGGTTCAACAGGCCCTCGAAGCCTCTATCGCCTGGGACAAATCCATTATGAAAGCTGTGAGTCCTCTTCAGTCTAATGTCCTGACTAGTTGTTTCCAAAATGAGGCGTCCATTTCACAGAAAGTGTCTTTGCAGAACTGCCAGTTCTGTCATTCTGGAGACAACGAGGACAAACTGCTGTTGTGCGATGGCTGTGACAAGGGTTACCACACGTATTGCTTCAGACCCAAAATGGATAACATTCCCGATGGAGATTGGTATTGCCACCAATGTCTAAACAAAGCGAAGGGGGAAAAGAATTGTATAGTTTGTGGAAAGAAAATCGGTAGGAATCTCCTGGTTTGTGAAGCCTGCCCTGTCGCTTACCACACAGACTGTATGACACCACCTCTTACTAAAGTGCCTAGAGGCAAGTGGTACTGTTCCAACTGTGCTTCGAAACATGTCAAAAAGAAGACCACCCGACGTTCTCAGCCGATTAGCTCGCCAACGCCCATAAAATCAGACGAAGTCAACAACTCTATTGAAAATCTGAATGCGGGCGGCGGAGGGACCGGGGAGGAGGAGAGCGCGGGACCAGCCGCTTCTGTGCCGCCACCGCCAGCTCCCAAACCTCGGGAGAAGTCTGGAAAGCGATTCGGCAAAGAAATGGCGGCCTGCAAGCAGATATTGGATGATCTTGAGAGTCACGATGAAGCCTGGCCCTTTCTCCTTGCCGTTAACACCAAACAGTTCCCCACGTACAAGAAAATCATCCGAAGTCCGATGGACCTCCAGACCATCGGAAAAAGGCTTTCCCACAACGAATACAAATCTCGTGAGGATTTCGTCTCAGACGTCCGGCTCATATTCGACAACTGCGAAACCTTCAACGAGGACAACTCCCCAGTCGGAAAGGCCGGCCACACCCTGCGACTCTTTTTCGAAACTCGGTGGGCGGAGCTGACCAGTGCCAAACCGTCAGCCGTCTAA
Protein Sequence: MEKENASAASEREKDRQAPSLLDPAALFGAFWPRPDGSNASAANANPLFSAYTGAYGGLLGRAGTPGAGFPAGANPYGTLSVAASQASALGINPASMGAWWSMAQQLAAQDYLAQLQFANMLPPYPMIPTPPHLSSNKTSHSKNSSSSSSSTTPSATVSVPTTSQPTSTSDSLVGVRLPPDTEIIKYTSSMVGPKIPGTTNRGRKKTISLDHPHLNSLKHRSHSNELPKTPYVGLDLSGKSKDAASVEDSFYRYGSDKSDRLDAVKSGQTNGRTSPPGPADDGPLNLSLKPDVSTNHNNNNSALQSLSALSQTLGQSERVDRRKPGPKPRRVPPFAPSDSSHPSSGSEENDSVILPHKDGRPRNLGRGISKPKKNTVASLLAQSRALGIKPGLEVSQLAALARATSNFEKDKEESSISSSPNSLHDQLQPLPLNLNRSFDDHKHTSYDGISEDSHSDMTDSSSDSDGDSHSRKRDRDSMSNDGGPGGKRRKVVIDEGKLREALAKGWKRETYITSVGRAGVKGEVVYTSPCGRTFRHFSDLVRFLDKQGSDLTREYFSFSCRILLGDYIESEQGKEPIRLSEGTLALKLQEMVAQHRAALDLNKQERDRMALAAKEAKRLAREEAAKQKEQLRLLKEQERNERQEQARKEREQRNQQLLEGRKRLAFTSEEKWRIIREIESGKSKSDVSRELGLANSTVATIWKQRGNVMPTPGASSARKKKQEELERQRIEGQQRKQQEREMKRQQAAIIKEQERERRRQHMALVKALEVRKRMEEREKKRLEQRAEKLATREKRIEQRKVEVELLRELRKPVEDMELSDPKPLPELPRIPGLKLTGQAFADTLMVHEFLRNFGETLGFDMESLPTLNSLQEALLNESEEAEEELLSVITQLVICGIEDPGIPQPARHTTLLNHSLRAADITHSSLSEILRIYLYANATGEVKATTGVHFEREKEKKVTEHHNNMDDTADETTGKNSAFFSLLKENQTYKMSEWLKKRPFLSLNPTKKAAILAFLCHELLQNKAVIRQIDSAIDTVAQLKRERWPLEANLRKLKHIQARRNKAMGVQCTKDGEAQADDEAEVESCNESDITQPEEDELAKINIGETLAVVSKQAEVNTKALADYSGQLRATCLGQDRYCRRYWCLSTGIYVEGVESADPEIFAAPDPEPVEEEQLPRKVEVKDEGTSVMEIEEQPHLPPPAKTPETNGTLDSPEPPVIKAEMRDSYVQVKDDGQQTELPLKDDSQQTELMLKDFSTPIKEEDSKDAMSEKSLTPKSLQFERLGECMEKESNAVNGCISLNSSHHEEHVQWFSILPKDPCDSTSITNSQPGYRCWAETAGELRIPQPGMYSGSPSPCPSPLPLPLSAEEAALLEQCRLHGLPKPGRPKPIPADFKKSWWKITEDTMKIILSKLEPRGVREREFLANITRLRTDHTWESTLKASTSGDPNKARFKTIEGEEEIVVPSPDGPLDWDEETALRIDLAALVAVEALEEKVASASMQLKGWKMPSKVTTCDIPFKPACVASDPSVNPIAVAKERLSNLFENIEKRYLKPPLGTNMGDLKLNQAANNTASTDDSDGGNRECKGLVVWKEALHKSQTAAQLSMVQQALEASIAWDKSIMKAVSPLQSNVLTSCFQNEASISQKVSLQNCQFCHSGDNEDKLLLCDGCDKGYHTYCFRPKMDNIPDGDWYCHQCLNKAKGEKNCIVCGKKIGRNLLVCEACPVAYHTDCMTPPLTKVPRGKWYCSNCASKHVKKKTTRRSQPISSPTPIKSDEVNNSIENLNAGGGGTGEEESAGPAASVPPPPAPKPREKSGKRFGKEMAACKQILDDLESHDEAWPFLLAVNTKQFPTYKKIIRSPMDLQTIGKRLSHNEYKSREDFVSDVRLIFDNCETFNEDNSPVGKAGHTLRLFFETRWAELTSAKPSAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00145587;
90% Identity: iTF_00386352;
80% Identity: -