Lhet018262.1
Basic Information
- Insect
- Leptopilina heterotoma
- Gene Symbol
- PLAGL1
- Assembly
- GCA_015476425.1
- Location
- JABAIE010000048.1:3986719-4003986[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 2.7 5.6e+02 2.9 0.1 10 23 305 318 304 318 0.95 2 11 0.0027 0.57 12.3 1.9 1 23 326 349 326 349 0.94 3 11 0.0051 1.1 11.4 4.3 1 23 386 408 386 408 0.98 4 11 6.8e-07 0.00014 23.6 1.8 2 23 448 469 447 469 0.97 5 11 1.1e-05 0.0023 19.8 0.5 1 23 474 497 474 497 0.96 6 11 2.5e-06 0.00053 21.9 0.4 1 23 536 558 536 558 0.98 7 11 9.3e-07 0.0002 23.2 0.9 1 23 568 590 568 590 0.96 8 11 1.2e-06 0.00025 22.9 1.4 1 23 596 618 596 618 0.99 9 11 0.00066 0.14 14.2 0.3 1 19 624 642 624 645 0.94 10 11 0.54 1.1e+02 5.1 1.1 8 23 659 674 659 674 0.97 11 11 0.0022 0.47 12.6 0.2 1 21 680 700 680 701 0.94
Sequence Information
- Coding Sequence
- ATGGAACAGCAGAATAAAAGTGAAATTACAAATTTAAGAAGTGAATTAGACAATTCGCATCAACAATGCAGAATTTGCTTAAAGTCACACTCTTCTACCTGGGATTTATTTCGCGATGGAAAAAATGTTATTCGCAAGTTGACCGCTTTCGCCAATGTACAGGTGGAAGAAGGTGACGGTTTACCTTCTGTCGTCTGTCCAGATTGTCGACAACTTGTCGATATTGCCTACGATTTTAAATGCCAAGTTGAAAATTCTGATATGAAATTACGAAACACCTTTTTAACAAAAGATTCATTGTCTTTAACACATTCAATTAACAAAGTAATATCAGATGCAATAGCAGATGAATTTTCACAAAAAGTTATTTCGTGCAACGTAGAAAATCGCAGTCTACCACTTAATGATATAAGTTCAAAAATTGAACATTTCTCAGTGCATTCTAATGAGCAACTAGTTTCATCGCCTTTAAATAATTCGACAAACATAATAGCATTTAATATCGCTGGAAATTGCGCAGAGAAACACGAACCTGTCGCTGAAATAATTGAAGAAAATTTCATTTATCAAGAAAGTGAAAAGTTAAATGTTTCCGAGACATTACAGGAAGAGAATTCATCGAGAGTTGATGGAAATATTCATCAGAACGCCGAAGGACATTTAGACATTGATTTCGAAGAAGAATATGTAAAAATAGAGGAAGCACAAAATCGACTGGAATTTACAAATGATAAAATCGAAAAAATTCCATCAACATTTGAAGCCGTTAATAATGTCACAGAAAATTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTATTCTCCAGTCGTACTGCATTGGAGAAACATGTTATTGTTCACAAATCGAAAACAAAATTACGCTATGTTTGTTATTTGTGTGAAAAGCAATTTTCACACGTGGGGAAATTAAAAAGTCATTATCAAGACGTTCACGAGAAGAATAAAGACGATGAGAAAATAGAACAAAATGAAATTAACGAAACGGAAAATGTGAAAAGAATCGATAAAGAAGGACATTCATCAGAAAAGAAAGCCTTTAAATTTTCCTGCAAAGTTTGTTCAAAACAATTCACGTATCATAAATCATTTGTATCTCACGCTAAAATACATCCCGAATATAATACAGATGAATTAATTAATGAATCGTTACCAGCAAAAGATACGGAGGGCTCAACGAAATCTAAAGAGGTGGAATCAGATGACGAGGAAATGCTAACTGAAGGTTTACAGTGTACAAAATGTGGTAAACTATTTGCAACAAAGAGAAATCTCAAACGACATCTTCTGACTCATACTGGCTTGAAGTACAATTGTCCCATGTGTGGCAAGGAATTCTCCAGAGTCGATAAGCTGAAAGAACATGAACAATCGAAGCATAAGGATGAAATGTTTGGTGATCTGTCAGAAGATGGTTTCGATGATGGTACAGATAACGATAATAAATCATCAGATCTTCCAGAAAATAGAAAGAAGGAAAAATACAACAGACCGCATCAATGTAATCTTTGTCCAAAAGCTTTTGCTCAGCCACAATCTTTGGCGAACCATATGGAGCGTCACAAGCGTGTTAAAGACACGCAAAAGCGATTTTTGTGCGAGGTGTGTAGCAAATGTTTTGCACAAAGTGGTTCACTGGTAGCTCACATGCGTACACATACAGGCGTTAAACCATACGTTTGCAATGTTTGTACGAAAGCGTTTACAAAAAGTACGTATTTACAGCTACACTTACGAACTCACAGTGGAGAAAAGCCCTACATTTGTCAGTATTGCAGTAGGGCATTTGCGCGCGCCAACACTTTAGCGAGACACATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATGAAATCCTTCAGACGATTGACTTCCCTTAATGAACATACTTACACGCACACTGGTCAAAGACCTTATGCATGTAAAATATGCGCTAAACGATATAATAACGCCGGCTCGTTGTATGCCCATACGAAAAAATGTAAATCACAACAACAATCTAACATTGTCCCGACCTATCCAGTCAGTACTGAGTCGACGGAAAATAATTTACAAAATAATCTTTCCTCCCCATCGAATCAATTAATTTCATCGTCACAAGTTTACTCTCAAAAGAAATTGATAGAAACCACAACGGTAACTCAACCTATTCCTGTACCTCAATTTATGATTGCTAATGTCCACAATCAAAAATCACTGACTAGCAATATCATTCAACCGTTTCCAGTCGAAGATCCGAATCTTTATGCCATGAGTACAAAACAGTTTAAAAATCCATACTATACCATTTATCCTAATATGTAA
- Protein Sequence
- MEQQNKSEITNLRSELDNSHQQCRICLKSHSSTWDLFRDGKNVIRKLTAFANVQVEEGDGLPSVVCPDCRQLVDIAYDFKCQVENSDMKLRNTFLTKDSLSLTHSINKVISDAIADEFSQKVISCNVENRSLPLNDISSKIEHFSVHSNEQLVSSPLNNSTNIIAFNIAGNCAEKHEPVAEIIEENFIYQESEKLNVSETLQEENSSRVDGNIHQNAEGHLDIDFEEEYVKIEEAQNRLEFTNDKIEKIPSTFEAVNNVTENXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLFSSRTALEKHVIVHKSKTKLRYVCYLCEKQFSHVGKLKSHYQDVHEKNKDDEKIEQNEINETENVKRIDKEGHSSEKKAFKFSCKVCSKQFTYHKSFVSHAKIHPEYNTDELINESLPAKDTEGSTKSKEVESDDEEMLTEGLQCTKCGKLFATKRNLKRHLLTHTGLKYNCPMCGKEFSRVDKLKEHEQSKHKDEMFGDLSEDGFDDGTDNDNKSSDLPENRKKEKYNRPHQCNLCPKAFAQPQSLANHMERHKRVKDTQKRFLCEVCSKCFAQSGSLVAHMRTHTGVKPYVCNVCTKAFTKSTYLQLHLRTHSGEKPYICQYCSRAFARANTLARHXXXXXXXXXXXXXXXMKSFRRLTSLNEHTYTHTGQRPYACKICAKRYNNAGSLYAHTKKCKSQQQSNIVPTYPVSTESTENNLQNNLSSPSNQLISSSQVYSQKKLIETTTVTQPIPVPQFMIANVHNQKSLTSNIIQPFPVEDPNLYAMSTKQFKNPYYTIYPNM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00883250;
- 90% Identity
- -
- 80% Identity
- -