Basic Information

Insect: Leptopilina heterotoma
Gene Symbol: ZFX
Assembly: GCA_015476425.1
Location: JABAIE010000048.1:2824961-2840871[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.9 3.9e+02 3.4 0.1 3 23 12 32 11 32 0.94

2 15 0.34 72 5.7 3.6 1 23 854 877 854 877 0.95

3 15 3.5e-05 0.0074 18.2 0.6 2 23 958 980 957 980 0.96

4 15 0.0057 1.2 11.3 0.1 2 23 993 1014 993 1014 0.98

5 15 0.00012 0.025 16.6 1.9 2 23 1017 1038 1016 1038 0.96

6 15 0.0025 0.53 12.4 0.3 1 23 1044 1066 1044 1066 0.96

7 15 2.8e-05 0.0058 18.6 4.5 2 23 1073 1094 1072 1095 0.95

8 15 0.37 78 5.6 3.7 5 23 1108 1126 1107 1126 0.97

9 15 2.5e-05 0.0053 18.7 1.5 3 23 1133 1154 1132 1154 0.97

10 15 0.011 2.4 10.3 0.3 2 23 1170 1190 1169 1190 0.97

11 15 7.5e-05 0.016 17.2 0.7 1 20 1196 1215 1196 1218 0.92

12 15 3.6e-05 0.0076 18.2 2.8 1 23 1226 1248 1226 1248 0.99

13 15 0.0026 0.55 12.3 3.2 1 23 1254 1276 1254 1276 0.97

14 15 4.7e-06 0.001 21.0 3.9 1 23 1282 1304 1282 1304 0.99

15 15 0.00048 0.1 14.7 7.0 1 23 1310 1332 1310 1333 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.9	3.9e+02	3.4	0.1	3	23	12	32	11	32	0.94
2	15	0.34	72	5.7	3.6	1	23	854	877	854	877	0.95
3	15	3.5e-05	0.0074	18.2	0.6	2	23	958	980	957	980	0.96
4	15	0.0057	1.2	11.3	0.1	2	23	993	1014	993	1014	0.98
5	15	0.00012	0.025	16.6	1.9	2	23	1017	1038	1016	1038	0.96
6	15	0.0025	0.53	12.4	0.3	1	23	1044	1066	1044	1066	0.96
7	15	2.8e-05	0.0058	18.6	4.5	2	23	1073	1094	1072	1095	0.95
8	15	0.37	78	5.6	3.7	5	23	1108	1126	1107	1126	0.97
9	15	2.5e-05	0.0053	18.7	1.5	3	23	1133	1154	1132	1154	0.97
10	15	0.011	2.4	10.3	0.3	2	23	1170	1190	1169	1190	0.97
11	15	7.5e-05	0.016	17.2	0.7	1	20	1196	1215	1196	1218	0.92
12	15	3.6e-05	0.0076	18.2	2.8	1	23	1226	1248	1226	1248	0.99
13	15	0.0026	0.55	12.3	3.2	1	23	1254	1276	1254	1276	0.97
14	15	4.7e-06	0.001	21.0	3.9	1	23	1282	1304	1282	1304	0.99
15	15	0.00048	0.1	14.7	7.0	1	23	1310	1332	1310	1333	0.96

Sequence Information

Coding Sequence: ATGGATTACGGGAGCAGCATGGGGCCTGTAGCATGTCCAGTTTGTACTCTTTATCTACGAGAAGGAATCAGTTTACAAAAACATTTGGATACACATCCGAAAGAACAAGTAATTGAGGCTCTTATAAAAGCCAGTGGTGCATCCGTCCCAAATCAGATACAGGAGCCCCAAAGTCAGATATCACCATTGCCAAGTCAGATATCACCATTACCGAGTCAGATATCACCATTACCGAGTCAGATATCACCAATACCAAGTCAAATTACTTCTCCGTCACCAGTGAATTCCGCCTCTCATGTTTCGCCTCAGTCTCCTTATCCAGTAGGTCCAGTTTTTGAATGCCCATCAACTCTAAATGCAGTTATCTCGCCACCACAATTCGCTTCATTCAGTTATCAACAGTTCGTCAATAATGGAACTGTCATGATACCTCAGTACGCGATGGCACCACAGAATAATCATATGATGCAAATGCTCTATTCTCCATATGGCATGTATCATCAGCAACCAATCTCAACCATGCAAATGATTTCACCTCTTGCTCACACAACGCCCCCTGCAACTGACAGCACAACAAATTCCACCATCAGATACAAGTCTCCGAATGCTTTAGCAGGAGGTGATTCTGTCATCAAATTGACTTCACCTGAAAAATCGTACAATTGTCCTGAACCTAGACCTGTTATATCGGAAATTTTAGAGGATACTGAAGCCTTGCTGCCTAATACAGACATTGATTTATCATCCCGTTCACCTGTTAATAAAGAACGGCCGGCCAAATGTGATAGAGTAACCAACGATCAAGTCAGAGTTGAGTATCGGGAACAACAAACACAAGCTTCTAATGAAGATGATCGCAGTGAAGAATTACCAACAGAACAACAAAATTACCCGGAAACTGCAAATCTTGAAGCAGAAAATAATGAGAATAGAATATTTCCGAATTTAGAACAAAAAGAAGCAGTGACATCTGAATTAATAATCGAAGATAGTGATATGGTTGTCGATAAAACATCTGATGATGCTGATGTTGAATTACCTGCTGATCCGATGGATAAAGAGGAGACTGAAAAGGAGACCGAAAGTGAGAAAACAGACGAACAAGAACTGGAGAAGCAGACAGCGTGGAATAGTTTTAAGGAATCTTGTGAAGATGAAAATGACCAAAGTCGGAAATCACCTGAGGTGGAACAATTAGAACATCTTTTGATAACAATCATAGAATCAGACTATGATGCCAGTACTGCACGTAATACCGATGTGCAAAAAGTTCTAATTTCCACTGATACTTTAGAAAGAAGTGAAAATACAGCCGACAGTGATAGCACCGATACTTCTGATTTAAACAAATCTTCCACAACTGACAGTAATTTATCAATTAATTTACTCGAGAGTAAAACCTATCACTATAAGCACAGTTTGTCAGCGCCTTCATCGCCAATTTTCTTCAAGAAATCTCATAGAACTCATTCGCGCCTTTCATTAAGAGATGACTTCCGATCAAATGAAAACATCTCTGCGTATCCTTTGGGATTCGAAGCAACGGCTTTAGAAAATTTTGTCAATAGAAAAAATGAAGAGGATCCCGATGCCGATATGGAGGAAGTTGCTTCCACTGTGCTATTCAAAGAATATCACGAAATTGAAGATGAACCTATGAGATCATACACACCATCATCAATTGGTAGCAGCAATTCTGTCCTGCGAGTGCGAACAGATCTCAATAAATCTGGACCTCTTTTGTCGAATCATCTACTCCATCAAACCATCAATGTGGATGAAGTGATATACGAGAAAATTAATTTCCCACAAATCGAATCATCTCCCGAGGAACATTTGCCCAGTACGAATATTCAAGAGAACATAAGCAATAAAGAATCAGAATCAGAGAAGTTGAAAATAAAGGATGAGAAACGAATGACATCAAAAGAAAGTGCCACAGTTCATAATTCTCATAATCAATTGACTGATAATATAACGGAGAATACATCTCGTCACATAGTATCAAAAAATTTAGATTTCGATGAATCTAATGGAAATTCAAATTCAAAACCCGCTGAATCCAACAAAATGGTCTCTCAAAAGCCAGCACCGGAACTTTTTAATATAAATGAAGATGCTCACAGTGGTCCAATGAATGTTTTTGAATTTGATGGTTTGCAAATATTGGTACCAAGTACTTTTATAAGTGAACCCTCCGATAAAGCAATCAGCGGTACGAGTCAACAATCAATGTCCAGCAGCGAAGGAGGAACTTGCATAGATGAAGAAATTAAAAGTATCAATATGCGAGCAGATGAAAGTATGCCACCAAGAGGGGAATTGTCGGAGCAAGAAAGCAATGAATGTACTGATCAGTCTACTTGGCAGATTTATATTGGTCAAGAAGCTTCACGTATGTCAACATCATATGATCTCATGGCGCGGGAAACTTGGGAAGAATCAGAAGGTTCAGACAATGAAATTGGAGGATCTCTTCTGGATTCTAGATCACTAGCTACGCATTTTACATCGAGCTTGTTTTTAGATCGTGATCGGAAAACGCCCACACGGCGAATTTTCAAGTGTACACATTGCACAGAGGTTTTTGAATGCCCCAAGGAACGCAGGGTTCATATTACAACAGTCCACAAAAATGCCGGTGCCAGTAACAGTAGGGAACCCATTCAACAAGCCGAAATGAAGGACATTAAATTGCTGGATGGACGCATGAATATGTTTGACGACATTTTCGTAGCTGGATTACATGTACCACAAACATATCATCAACCTTTGTTGCATCAACTCCAACCACCGCAACAATTGGACGAGGGACGAGTTGAAACTGACATAAAAGTAGATAATTTGAGAGTTTCAAGCACAATTGAAATTTCATGCAATATTTGTAACCAAAGTTTCTCCGGTGAAAAGTCATTGCAAATTCATCAAAGAAGAATGCATATTAAAGAGGCCGTGAAGCGCGTTCGGGAAAATGCCAAGTGTCAAATTTGTAATCAAGAATTTCCTTCGGTTATTTTGTTCAATGCTCATTTGAAGATTCATCCCCTAGAATGCGGCCAGTGTGGTAAATATTTTTATAGGAAACAAAACTTCAAGTTGCATGTGAAGCGACATCTTGGAATAAAACCATTTCCTTGTACAGTTTGTGACAAGGCTTTTCTCACGAAACAAAAGTTGGAAGAACACACCAACGGCCATACTGGCAACGCTCCTGTCAAATGCAATCTATGTAACGAAACATTTCGACGCTATTCAAATTTAACACAACACAAGAACAGACATCATTTGCACGTGAAGAAAAAGTTGAAGGACTACATTTGCCATTGCGGGGAGATATTTCACACGAAGAAGAAACTGGCATGGCACAAGGAGACTCACGATGAAAAACCAAAAGCATGTACATACTGTAACGAGAGATTCATTCATATGGCCAGTCTAACTCGCCATATGCGTCGCGCTCACAACCGAAGGTTCGTTCCTGATGCTCAAAGAGAAAGTGAAAATGTAGAATGTCCGATATGTAAATGCATTTACTTACGATCATCATTAGCTGTACATATGAGAGTGCACAATGGAGAGCGACCTTACGAGTGTCAAGTTTGTTCTAAAGCATTTAGTACGAAGTGGAATTTGCAGCTGCACAAGTGGACGCATGCGGCAAGAAGTACTAAACCATTCAAGTGCAATCAATGCAATGCTGCTTTTTATCGACACAGTGATTACACAGCACACATGAATTCTCACAGGAATGTTCGTCCATATACGTGCAATTACTGTGGGGCTCAGTTTATTAGAAAATACAATTGCCTTAGGCATGTTAAAGAACACGAAGAAAATAAAGCTTATACATGTGATGTTTGTAATAAAACTTTTCATAGATCGTATTACCTCAAAGAACATTTACGTGTGCATTCTGGTGCAAGACCATATTCCTGTCATATTTGTGGTAAATCAAGTAGCACTAAATCCAATCACAATAAGCATGTGAGAATTCATCATGCACGTGAACCTGTAAATACCGAAAATTAA
Protein Sequence: MDYGSSMGPVACPVCTLYLREGISLQKHLDTHPKEQVIEALIKASGASVPNQIQEPQSQISPLPSQISPLPSQISPLPSQISPIPSQITSPSPVNSASHVSPQSPYPVGPVFECPSTLNAVISPPQFASFSYQQFVNNGTVMIPQYAMAPQNNHMMQMLYSPYGMYHQQPISTMQMISPLAHTTPPATDSTTNSTIRYKSPNALAGGDSVIKLTSPEKSYNCPEPRPVISEILEDTEALLPNTDIDLSSRSPVNKERPAKCDRVTNDQVRVEYREQQTQASNEDDRSEELPTEQQNYPETANLEAENNENRIFPNLEQKEAVTSELIIEDSDMVVDKTSDDADVELPADPMDKEETEKETESEKTDEQELEKQTAWNSFKESCEDENDQSRKSPEVEQLEHLLITIIESDYDASTARNTDVQKVLISTDTLERSENTADSDSTDTSDLNKSSTTDSNLSINLLESKTYHYKHSLSAPSSPIFFKKSHRTHSRLSLRDDFRSNENISAYPLGFEATALENFVNRKNEEDPDADMEEVASTVLFKEYHEIEDEPMRSYTPSSIGSSNSVLRVRTDLNKSGPLLSNHLLHQTINVDEVIYEKINFPQIESSPEEHLPSTNIQENISNKESESEKLKIKDEKRMTSKESATVHNSHNQLTDNITENTSRHIVSKNLDFDESNGNSNSKPAESNKMVSQKPAPELFNINEDAHSGPMNVFEFDGLQILVPSTFISEPSDKAISGTSQQSMSSSEGGTCIDEEIKSINMRADESMPPRGELSEQESNECTDQSTWQIYIGQEASRMSTSYDLMARETWEESEGSDNEIGGSLLDSRSLATHFTSSLFLDRDRKTPTRRIFKCTHCTEVFECPKERRVHITTVHKNAGASNSREPIQQAEMKDIKLLDGRMNMFDDIFVAGLHVPQTYHQPLLHQLQPPQQLDEGRVETDIKVDNLRVSSTIEISCNICNQSFSGEKSLQIHQRRMHIKEAVKRVRENAKCQICNQEFPSVILFNAHLKIHPLECGQCGKYFYRKQNFKLHVKRHLGIKPFPCTVCDKAFLTKQKLEEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLHVKKKLKDYICHCGEIFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCNAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYSCHICGKSSSTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00883252; iTF_00880678;
90% Identity: iTF_00883252;
80% Identity: -