Basic Information

Insect: Leptopilina heterotoma
Gene Symbol: SPOPL
Assembly: GCA_015476425.1
Location: JABAIE010000172.1:58668-64546[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.1e-21 4.7e-19 70.2 0.1 9 109 55 151 50 152 0.89

2 6 7.8e-18 3.5e-15 57.7 0.3 28 109 197 276 186 277 0.92

3 6 1.9 8.6e+02 1.7 0.0 79 107 278 306 274 308 0.87

4 6 2.1e-21 9.3e-19 69.2 0.2 8 107 394 489 390 492 0.89

5 6 8.4e-30 3.8e-27 96.2 0.3 3 109 582 685 580 686 0.94

6 6 3.9 1.7e+03 0.7 0.0 80 108 688 716 685 717 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.1e-21	4.7e-19	70.2	0.1	9	109	55	151	50	152	0.89
2	6	7.8e-18	3.5e-15	57.7	0.3	28	109	197	276	186	277	0.92
3	6	1.9	8.6e+02	1.7	0.0	79	107	278	306	274	308	0.87
4	6	2.1e-21	9.3e-19	69.2	0.2	8	107	394	489	390	492	0.89
5	6	8.4e-30	3.8e-27	96.2	0.3	3	109	582	685	580	686	0.94
6	6	3.9	1.7e+03	0.7	0.0	80	108	688	716	685	717	0.89

Sequence Information

Coding Sequence: ATGCATTTGCATGCTATTGTAGAAACACCTTTACAACCAACTGAGTGTCAAGGTCGCGATTTTGACATTTTTCGCCTTTCGATGTCAGAACCAGATGTGGAGTGTTTGTCACCGAAAATTCAAAATGATAATGATTATCGGAAAATTTATTCGAATTTGAAATATTTAAGCGACTTTAAAATTACTAATCGAGGAAAAACATTTTCTGTTCATAAGGTTATTTTAGCGAAAGAATGGCCTTATTTTCATGAGTTATTTCAAAAGGAAAGAGAAATTAAGAAACTCAATAACCATGATTTGGATATAGATCCGGAAGCATTTAATATCATCCTTCATTACATGTACTCCAATGAATATCCAAATCGAGGTCGATACGATGTTATTCTTGCTGCAGCGGATATTTTACAAATGGAAAATTTAAAAAATCACTGTGAAAGAAAATTGGAAAAAGATCTATCTCAAAAAACTGTTTGTCAGCTTTTGACACTTGCTGTAGAAAGTTCTGCAAAGCTTCTATTCAATGCTTGCATGACTTTTATTTTAAAAAACATTCATTCAATTGATTTTCAAAGTCTAAAATCTAAGCCACTCGTTGTATTAACAAAAAGTCCTGTTTTTGATAGAATGCTTTCGAGTGAAATGAAAGAAGCTCCCACGAATGTTGTAGTGATTGAGGACATGGAACCAGAGGTTTTTTACGAAATTCTAAGGTACCTTTATACAGGAGAAGCGAATGTTGAACAATATGCTTTTGAGATTCTAAAAGCTGCCGATTTTTACAATATAGAGGATTTGAAAACGTTTACTGAAAATTATTTGGCGAAAAATTTAACTGACGTGAATGTGGTCAATGTTGTTAAAATTGCCCAAACATACAATGCATCATCTCTTTTCAAAGATTGCACTAACTATGTTGTTAAGTTAATGATTTCTAATCTGAAAATAAAGAAAAAAAATTCAATTTCTTTGAAACTCTTCGCTGATTTTCAAAATAATATTTTCTACGAATTTTTGAAAGTTTTGACCAATTCTTGTAAAATTGAGTATTTATCTGAATTTTGTTATCCTATTCCACGTTCGGTTCGTGGAATACAAGTTGAACACATGTCAGAAGCCGAGGAGAGTTTGTCATCGAAGATTAATGAAGAATATGAGAAGTCGAAAATTTATACGAACTTGGAATTTTTGAGCGACTTTAAAATTATTACTCGAGGAGAACCATTTTGTGTTCATAAGGTTATTTTAGCGAAAGAAAGTCCTTATTTTTATCAATTATTTCAAAAAGATGGAGAAATTAAGGAACTTAATATCCTTGATATTGATATAGAACCGACAGCATTTAATAACATTCTTCATTACATGTACTCTAATGAATATCCAAAGCACGGCTCATATGATGTTATTCTTGCCGCAGCGGATATTTTGAAAATGAAAAATTTAAAAAATTACTGCGAAACTCAAATAGAAAAATTGATAACTACGGAAAATGTTTGTCAATTTTTAATATTGTCGGTAGAATTTTCCGCCAAGATGCTATTCGAAGATTGTATGTCTCTTATTTTGAGAGGTATTGATGTTCTTGATTTTTGTATTCTACAATGTAAACCACTCGTTGTTTTAAGTATGTTGGAGGAAATTTTCGAACGAAGATGGATGATGGATTCTTATGTAATTACTGAATCCATTAATCTTTCATTTGAGAAAAAGATTGAAACGAATCCGAATTGTTTTCAAGGAATTGATTCATTTTTAAATAATGAAAAATATAGTGACGTAACTTTTATTGTCGGAGAAGAAACTTTTCGAGGCCATAAAATGATTTTATCAGCAAAAAGTCCTGTTTTTGATAGAATGCTTTCGAGTGAAATGAAAGAAGCTCTCACGAATGTTGTAGTGATTGAGGACATGGAACCAGAGGTTTTTTACGAAGTTCTAAGGTACATTTATACAGGAAAAGTGAAATTTCCTCAAAATGTTTTTCAAATTCTAAAAGCTGCAGATTATTACAATATAGAGGATTTAAAAAATTTTACTGAAAAATATTTGGCGGAAAAGTTAACTGACTTGAATGTAGTCGATATCGTCAAATTTGCAGACACGTACAATGCTTTTTTTCTTTTAAGACATTGTTCTCAATATATTGTTAAGAGAATGATTTTTAAACTAGAAATGGGAGAGAAAATTCCATTTTCTTTAGAAATGTTTGTTGATTGTCAAAATAATTTTTTCTACGAAATTCTAAACGTTTTGATTGAGTTTTGTGAAATTAAGTTTATTGAATTGAATGAATCAATTAGTGATTATAAAGAGCCTGAAGAAGATTGA
Protein Sequence: MHLHAIVETPLQPTECQGRDFDIFRLSMSEPDVECLSPKIQNDNDYRKIYSNLKYLSDFKITNRGKTFSVHKVILAKEWPYFHELFQKEREIKKLNNHDLDIDPEAFNIILHYMYSNEYPNRGRYDVILAAADILQMENLKNHCERKLEKDLSQKTVCQLLTLAVESSAKLLFNACMTFILKNIHSIDFQSLKSKPLVVLTKSPVFDRMLSSEMKEAPTNVVVIEDMEPEVFYEILRYLYTGEANVEQYAFEILKAADFYNIEDLKTFTENYLAKNLTDVNVVNVVKIAQTYNASSLFKDCTNYVVKLMISNLKIKKKNSISLKLFADFQNNIFYEFLKVLTNSCKIEYLSEFCYPIPRSVRGIQVEHMSEAEESLSSKINEEYEKSKIYTNLEFLSDFKIITRGEPFCVHKVILAKESPYFYQLFQKDGEIKELNILDIDIEPTAFNNILHYMYSNEYPKHGSYDVILAAADILKMKNLKNYCETQIEKLITTENVCQFLILSVEFSAKMLFEDCMSLILRGIDVLDFCILQCKPLVVLSMLEEIFERRWMMDSYVITESINLSFEKKIETNPNCFQGIDSFLNNEKYSDVTFIVGEETFRGHKMILSAKSPVFDRMLSSEMKEALTNVVVIEDMEPEVFYEVLRYIYTGKVKFPQNVFQILKAADYYNIEDLKNFTEKYLAEKLTDLNVVDIVKFADTYNAFFLLRHCSQYIVKRMIFKLEMGEKIPFSLEMFVDCQNNFFYEILNVLIEFCEIKFIELNESISDYKEPEED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -