Ldro010299.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Leptopilina drosophilae
Gene Symbol
BAZ2B
Assembly
GCA_032873175.1
Location
CM065480.1:4400052-4442262[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.9e-21 3.8e-17 63.0 0.0 5 76 594 665 592 666 0.94

Sequence Information

Coding Sequence
ATGGAGAAGGAGAACTCCGCGTCGGGTGGCAGCGGAGGCGGCGGGGGCGGTAGCGAGGCAACGGCGACGCCGGGCGCCACCTCTGCCTCCGAGAAACTCCAGGCGGACCAAGCCAACCCCTTGCTCGATCCTGCCGCCCTTTTTGGTGcaTATTGGCCGAGAGGTGACAGCACAGCGTCATCACTCTTTGGAGGAATGCCGGGAGGATATGGTTTGGGGGCACATCATTTGCCCTCGGCTTATGCCATTTTGGGTCGAGGTGGTTCTGCTCCTGGTTTTGGTGGTCATACACCAGCTTCCGCACCACCTCCGCCACCCTATTCACACAGCAGTCTTGGGACCCTCAGTGTTGCTGCCAGTCAAGCAGCGAGCTTAGGTATTAATCCGGCGAGCGCAGCTTGGTGGACAATGGCTTCGCACTTGGCTGCGCAGGACTACCTCGCGAGGTTACAAGGAGCCGCAGGACTTTCAGGGTTTCCACCAAGTGCAGAAAGCCTTCTACCTCCTTATCCCACTTCCTTACTTAATCCATCGTCCCTTTCCTCTCACAAGTCCAGTAAGTCTAAGTCAAGCAAGAGTCACAAGACTCCAACGAGCAGTAGCAGTTCAACAACTCATAGTCTGACAAATACTCTGACAGTAACAAGTCAGGCTCCAGTAACGACTACTCATCACAGTACTTCTTCAACGAGTAGTACAACCAATTCGCAACCGAATGTCGTTAGTGATCCTAGCAGTATACTGGGGGGCGTTCGTTTGCCACCAGACACGGAAATTATCAAATATACGTCAAGTATTGTTGGTCCAAAAATCCCCGGAACAACGAATCGAGGCAGGAAGAAGACGATATCGCTCGATTCGCCGAGTGTCAGTGTTCATACTCCATCTGGTCCAGGATTATCTGGTCATCAAACTAATACTCCACCTTCTTTGATGATTGAGGCGCGAAAATTCAATCGCACTCCGaatGAATCGAGCGAGTACAGAGATAACGCGGACAGGGTCGAAGTGATTAAATTGCCGGCGCATTCGACTAACGGTTCTATTCTTTCGGCTCCTACATACACGACCAGCAATACAAGCAGTGCAAATGACGCGGACACACCTTTAAATCTTTCTTTGAAACCTTCCTCGACGAGTAGCAGTTCACCAACCGCTAGTAGTCAACCCCTCACCCAACTCAGTAATCTGAGTCAATCGCTACTCGCATCTGATCGAACATCGCGGCGAAAACCGGGACCGAAGCCGAGAAGAGTGCCACAGAATTCAATGCCGGTACCGCCATCGCCGTCGCCATCGTTGGCGCAATTATTTGCAGCCGCTGATTCGCCATCGCGACCAAGCAGCGGCAGCGAGGAAAGCGAGAGTCCAAGTGCAACGCATCATAAAGATGGAAGACCAAGGAATCTCGGTCGCGGTGTATCGAAACCAAAAAAGAATACAGTCGCGTCACTTTTGGCGCAAAGTAGAGCCCTAGGTATTAAACCAACGCCAGGTTCACTTGATCCAAATGTTCCTTTGTCGCACCAAGTCTCATTACTCAGGTCGAATATACTCGCTGCTCAACAATTCAACGCGTCTCTCTTTCAAGGCGACGATAAAAATCAAAAATCTTTACAGGAGAAGATGAAAAATAGACTGTTGGAAGTCTCGGGCGAGGAAAGTAATATGGACGTGACcagtgagagtgaaagtaatACTGACGCGATTACGGACACTGATGACGATAATCCTGAGGGCATACCGAGCGCAAAAAAGAGGAAGCTTAATTACAGTGAGAAAGATCTTCAAATTCCTCTCGAGCGCGGATGGAAGAGAGAAACGATCATCAAGGGTCTTGGGAAAACCGGAGTCATCAAAGGCGACGTTTCTTATCACAGTCCTTGCGGTAAAACATTTAGGAGTAGCCCTGAACTTCTcaagtttCTCGAGCATCAAAGTCCGGTTGAATTGACACCGATGAATTTCTCGTTTTCATCAAAGCCACTTGTTGGCGAATTCCTTCAGCCGACGATGGGTTTGGCCGAGGCCGAATTCGTGCGACTCAGCTCTCAAGAAGTTGCGAGAAGACTAGAAGAATTAAAAGCCGCTGGCGGCTTCAGGGACGGTAGGGTCAATAATCAATACGAAAAGGACAAATTGGCATATGCCAAAAAACTCGCCAAAGAAGAAGCGCAACGTCACAAGGAGCAAGCCAGGTTACTGAAGGAGCAGGAAAAGAATGAGCGCCAGGAAGCCGTTAGACGAGAGCGTGAGATCAGGAATCAGCAGCTTTTAGAGGGTCGAAAGCGGCTCGCGTTCACGATCAAACAGAAAATGAAGATCATCCAAGAGATTGAGAGGGGAAAGAGTAAGAGCGATGTGGCCCGGGAACTTGGATTGGCGAGCAGCACTGTGGCGACAATATGGAAAAATCGTGAGAGCATCGCCGAGAGCTGGAGGAATCGTGACGTTATGCAGTCGGACATGGACATCGAGTCGGCAAAGAAAATCAGCGCCAACGTTGTTGTCAATCTTGGATCATCGCCATTGCTGTCAACATCATTGCTGTCAACGCCACTATCAACAGCGTCGACAACGACAACGCCACTCATCACAAATGTGACGACATCATCGACATCACCCTCATCACAATTGGACAACATGCACCAGATCCACACTCTAACGCAAAATCAGGAACTTCTGCAGGAGGTAAGAAGCTCTccctga
Protein Sequence
MEKENSASGGSGGGGGGSEATATPGATSASEKLQADQANPLLDPAALFGAYWPRGDSTASSLFGGMPGGYGLGAHHLPSAYAILGRGGSAPGFGGHTPASAPPPPPYSHSSLGTLSVAASQAASLGINPASAAWWTMASHLAAQDYLARLQGAAGLSGFPPSAESLLPPYPTSLLNPSSLSSHKSSKSKSSKSHKTPTSSSSSTTHSLTNTLTVTSQAPVTTTHHSTSSTSSTTNSQPNVVSDPSSILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDSPSVSVHTPSGPGLSGHQTNTPPSLMIEARKFNRTPNESSEYRDNADRVEVIKLPAHSTNGSILSAPTYTTSNTSSANDADTPLNLSLKPSSTSSSSPTASSQPLTQLSNLSQSLLASDRTSRRKPGPKPRRVPQNSMPVPPSPSPSLAQLFAAADSPSRPSSGSEESESPSATHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPGSLDPNVPLSHQVSLLRSNILAAQQFNASLFQGDDKNQKSLQEKMKNRLLEVSGEESNMDVTSESESNTDAITDTDDDNPEGIPSAKKRKLNYSEKDLQIPLERGWKRETIIKGLGKTGVIKGDVSYHSPCGKTFRSSPELLKFLEHQSPVELTPMNFSFSSKPLVGEFLQPTMGLAEAEFVRLSSQEVARRLEELKAAGGFRDGRVNNQYEKDKLAYAKKLAKEEAQRHKEQARLLKEQEKNERQEAVRREREIRNQQLLEGRKRLAFTIKQKMKIIQEIERGKSKSDVARELGLASSTVATIWKNRESIAESWRNRDVMQSDMDIESAKKISANVVVNLGSSPLLSTSLLSTPLSTASTTTTPLITNVTTSSTSPSSQLDNMHQIHTLTQNQELLQEVRSSP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00882026; iTF_00676722; iTF_00460520; iTF_01393519; iTF_01392769; iTF_01390214; iTF_01391974; iTF_01389427; iTF_00980119; iTF_01391103; iTF_00011095; iTF_00089543;
90% Identity
-
80% Identity
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