Basic Information

Insect: Leptidea sinapis
Gene Symbol: ZFX
Assembly: GCA_905404315.1
Location: FR990185.1:1826029-1843341[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 2.9 3.9e+02 2.9 0.3 2 23 6 27 5 27 0.95

2 13 0.00069 0.094 14.3 1.5 1 23 1033 1056 1033 1056 0.94

3 13 1.7e-06 0.00023 22.6 1.4 2 23 1156 1177 1155 1177 0.97

4 13 3.6e-05 0.0048 18.4 1.7 1 23 1183 1205 1183 1205 0.98

5 13 7.6e-05 0.01 17.4 3.0 2 23 1212 1233 1211 1234 0.95

6 13 0.0063 0.84 11.3 0.6 1 23 1244 1266 1244 1266 0.98

7 13 0.012 1.6 10.5 0.7 3 23 1273 1294 1272 1294 0.96

8 13 0.22 29 6.5 2.2 3 23 1312 1331 1310 1331 0.96

9 13 0.00019 0.026 16.1 1.0 1 20 1337 1356 1337 1359 0.89

10 13 0.00083 0.11 14.1 1.3 1 23 1367 1389 1367 1389 0.98

11 13 0.005 0.67 11.6 7.2 1 23 1395 1417 1395 1417 0.98

12 13 0.0001 0.014 17.0 1.0 1 23 1423 1447 1423 1447 0.97

13 13 0.00036 0.048 15.2 2.3 1 23 1453 1475 1453 1475 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	2.9	3.9e+02	2.9	0.3	2	23	6	27	5	27	0.95
2	13	0.00069	0.094	14.3	1.5	1	23	1033	1056	1033	1056	0.94
3	13	1.7e-06	0.00023	22.6	1.4	2	23	1156	1177	1155	1177	0.97
4	13	3.6e-05	0.0048	18.4	1.7	1	23	1183	1205	1183	1205	0.98
5	13	7.6e-05	0.01	17.4	3.0	2	23	1212	1233	1211	1234	0.95
6	13	0.0063	0.84	11.3	0.6	1	23	1244	1266	1244	1266	0.98
7	13	0.012	1.6	10.5	0.7	3	23	1273	1294	1272	1294	0.96
8	13	0.22	29	6.5	2.2	3	23	1312	1331	1310	1331	0.96
9	13	0.00019	0.026	16.1	1.0	1	20	1337	1356	1337	1359	0.89
10	13	0.00083	0.11	14.1	1.3	1	23	1367	1389	1367	1389	0.98
11	13	0.005	0.67	11.6	7.2	1	23	1395	1417	1395	1417	0.98
12	13	0.0001	0.014	17.0	1.0	1	23	1423	1447	1423	1447	0.97
13	13	0.00036	0.048	15.2	2.3	1	23	1453	1475	1453	1475	0.97

Sequence Information

Coding Sequence: atggatCAAAGGGTTCAATGCCCTGTTTGTACATTATACCTTCACAATGGGATGTCATTGGAGTCTCATTTGGATACTCACCCAAAAGATCAGGTGATAAAAGCACTTTGCAGTTTATCTGCCAAAAAATCTAATGATTCAACCGTTACACTAACACCAAGTAGCTCAGAGGGATCTTACAGAAGCAGAACACCTTTAACAGATGATAGTGTAAGATGGTCAACCTCAAGACGGAGCACAGATAGTGGATACTGGCCTAGAACCCCTAGTAGAAATAAATCAGCATCATCAAATGTCTCCAGTAACTGTAATCCTGAACTTCAAAGTGGTGCATCTCATTTtgagaataatttaataaataacagtgcTGAATTCTCAGACTGTGAGGTGAAATCTGTCAAGAGCTCAAATGCATTTACTCCAAATGTTCACCTAACAACTGATTACAACCAACAATATCCATTCTATTCTGAAACTCCCGATGAGAGTGAAGTTAAGTATTCACGAAGTACTGATTATAATGTTACTGATAATGGAAACCAAATTTTTACATATAATGTACCAATTGTAGGTAATATGAAACTACCACCCAGAATTGTACCTGCAAATGCAACAAGAGGAAACAACAACTTCattaaatttataccaaaatcAAACAATATGATGGTTAAAAACATTGGAGGTGTAAGATACATGGCACCTAGTGTAAAACCATATTCAATGATGTTTTCTGGAAATAGCATGGGATCAGATATTTTAAGTCCAAAAAACCTAAGTCAGCCAATAGATGGTCAGTTTAATCAAATGGCCCATGAAGGAATAGCACCAAATGCAACTTCTGTTACACAAAATTCACAAATTATCTACAGGGAGATGGTTCACAGTGTTGATGGCAAACCTTATATTTCTAATGTTCCACAGATGCTGAATGGTAATGATAATGCAGCACAAAACAGCTCAATGTATCAAAATATGATGGTTATTGACCAGTTTGGTAATACATCTTGTATGTACAATACACCACCATCTAATTCTATGACTAAAGCTGAGCCAGTCTCCAATGAGTCAAACAAGACCTTGATAATTGAAGTGAGCCCCATGTCAGCAACAGATGAGAAATATATAAAACCAGAAATACTTAATAACCCCACCACTACAGTATCAGATAAATTACATACTTCATTACCCAGCTCTTGTAAAGGTTTGAAAATTCTTAGTAATATTAAAGTTGAGGTTCCTGTTAAGCATCACAAATATATGGTCAACACTGTGATGGATCTCACTGAATCTGATGAGTTGAGCTATGTTCAAAGGACTCCATCACCTGAAAATAGTTTGCTAGATTTAGAAGAGAAGAAAGAAATTCCAAAACTAACTGATGATTGTGCTCAACCATGTACCTCAAGCAATGACAGTTTAATAACTAATTCATTATCAGTTATAAAAAATGTGGGAAAGTTGCATCCTGAAGATGTTTCTATTAAAGAAGATAAAATGGAAGATGAATTTTCTGACAGTTGTCCAGTACCTGATCTTATTTGTAATGAAAAACCATCTATATCTCCATGTAGTGAATTGTTGGAAAACAGTGAAAACTCTATGGATCAAATAACATCAACTAAGCCTGATCCgtcaatcaaaattgattccaaaGATGAATTGACTAGTTCACttgaaatcaaaattgattccaaaGATGAATTGACTAGTTCACttgaaatcaaaattgattccaaaGATGAATTGACTAGTTCACTTGAATTGTTAGCAGGTAACAATAAACTGGATCATTACAGTCCTGACACAAGTTCAGATTTCAAAACAAAAAGTGAAATTTATGAATCAGGGTTGGATGCAGAAGATCTAACATCCGGATCTAGTTCTCGTTTAAGTGTTTCACCAAGTCCAGACCCTTCCATACCAGAATCATCTAGACAAAATTCAACATTGAAGTCTGAGTCACCCAGATCctctattaatttaaatcttcaAGAGGAACGCAAGGTACGAAACCCACCAAAGCCTCGTAATATACCATTaagtttgaataatatatttgttaaaaagcacaaaaaaattcttaaaataaaaaataaaaaatttgcttCAAAAGTAGTCCAACCTAAACAAGAACCACAGCCATCTTCTTCAAATACTGTGCcagtagaaatattttttgattcaAGTGTTGTAAAGAAATCTGAAGATACTGAGGACAtaaaagaggatataaataaaacagaagacatttgtaataaaaatgaaGTTGATGCTGATACAGAGGAACAATCAATGGATATTGAACCTGTTGCACCCTCCACTATTAGTCATGAtgacaaatcaaataaaatggacattttacatattaaggAAGAGGTTAACACTAGTTATGAATTTAGTTGTGAAGTAGATAGATGCAATAATGATGATGCACCTTTTGATACCATACGTCCAATTAATGTAATTACATATGGGAATATTCCGGCCGACAAATTTGATGATCATTCAGACCATGAAGAACTTTTGGATTCGGAAACtacaaaaagaaataaacagtTTGTTAATATGATGAGTGAAAATTATTTTGGAGACAATATCTATGCTGACTATTTCACACCAGACCATGTAGAAGCTTTTGATGCAGACAAAGAGTCGAACGATTCAGAAAGACCGGATGATGTATGGGGGGAGCCATCTCAGAAGCGAAATGAATTTGTATTACCAAATTTAATTGACAACAGTTATAAAATTCCGTATAGCACTAAGGTACACTATGATGGGAATGAAAGTGAAAGAAAAATTGAATGTAGCGAGGAACCAGACAACAAGGATGATATTTTGAGTGAAAGCAGAAGTGAAGGAGAGCCACCCTTGAATATATGTGCTGATGAACACATGCCACCTAGAGGAGAACTTAGTGGCCAAGAGAGTAATGGGGACATGGAATCACCATGGAGTCGGATGTATAGTGAAGTGACACCCACGGAGCCTTACGACTTGATTGCTAGAGAGAGTTGGGTGTCTGATGGTTCAGATGTTGATGTAACTGAAAAGAAAGATAACTTGGATGATGATGTTCAGTACAAGTGTCGTCTTCATACGTGCACACAGTGTGGCCTCAAGTTTGCCTCGCTAAAGGAACTGCGGGCTCACAGAACGAACGAGCACGTCACGGCAACGTGCTCGGCGTACAAAACCTACAGTCGCATGATCACAGCGAGATCTATCAAGAAAGAAGAGAAGATCAATGATAATATTCTAGCAGGGAAACATCTATTTGATACGGATGTGACGGACCCCAAGGCGGCCCTACAAGAGTATGATATTCTAAGGGATTGTAAACCGGAAATTAAGAGTTTGATCAAGCAGGAGAAGAAGAGGAAAAGAAACTTCATCTGTGAGATATGCAAGATTGACCAGGGCAACGATGTGGCATTCAATGAACATCTGAAATTGCATCCGTTGGAATGTCAGACTTGTGGGAAAAGGTTCTATAGACGAGCAAACCTTTCGCTGCATATGAAGACACATCTGGGGATAAAGAACTATAAATGTGAAGTATGCCAGAAGCGGTTCATAACCCGACAGAAGTTGAATGAGCATCGCAACATCCACACGGGCCTGGCGCCCGTTAAGTGCACCGTGTGTGACGAGACCTTTAGGAGATACTCCAATATGGTGCAGCATAGAAATCGTCACCACCTCAAGAAGAAAGCGAAGGTGAAGGACTTCGTGTGCCACGCGTGCGGAGCCGTGTTCCACTCGGCGGCCAAGCTGCTGTGGCACAAGGAGACCCACGACGAGAAGCCCAAGGCGTGCCTGTACTGCAGCGACAGGTTCGTGCACGCGGCCTCGCTCACACGCCACGTGCGCCGCGTGCACAACGAGTTCTACCTGTCCGACAAGCTGCGGGGCAAGGTGGACAACGTGCACTGTCACGTGTGCAAACAGGTGTATCTACGCACAAATCTTCGAGCCCACCTCGAGATTCACAGCGGCAAGCGTCCCTACCTCTGCGTGGTGTGCAACAAATCGTTCACCACCAAATGGAACCTCAAGCTGCACAGGTGGACGCACATGAGCCGGTCCGCCAAGCCCTACAAGTGCACCCTTTGCAAGGGCGCCTTCGTCCGCCACTCCGAGTACATCTCGCACATGAATGCTCACAAGTCGGTGCGGCCATACACGTGCAACTACTGCGGGTGCCAGTTCATAAGGAAGTATAACTGCCAGCGCCACGTCAGGGAACACGAAATGGCGAAGAAGTTTGTGTGCAAAGTGCCCGAGTGTGGTAAGTCCTTCCATAGGGGTTACTACCTGTCCGAGCATATGAAGGTTCACAGTGGGGCACGGCCGTTCGCTTGCAATATATGCGGGAAGACTTCTAGTAACAAATCTAATCACAATAAACACGTTAAGATACATCAATTGAGAGAGACTGTCGCGACTGAAGCGTAA
Protein Sequence: MDQRVQCPVCTLYLHNGMSLESHLDTHPKDQVIKALCSLSAKKSNDSTVTLTPSSSEGSYRSRTPLTDDSVRWSTSRRSTDSGYWPRTPSRNKSASSNVSSNCNPELQSGASHFENNLINNSAEFSDCEVKSVKSSNAFTPNVHLTTDYNQQYPFYSETPDESEVKYSRSTDYNVTDNGNQIFTYNVPIVGNMKLPPRIVPANATRGNNNFIKFIPKSNNMMVKNIGGVRYMAPSVKPYSMMFSGNSMGSDILSPKNLSQPIDGQFNQMAHEGIAPNATSVTQNSQIIYREMVHSVDGKPYISNVPQMLNGNDNAAQNSSMYQNMMVIDQFGNTSCMYNTPPSNSMTKAEPVSNESNKTLIIEVSPMSATDEKYIKPEILNNPTTTVSDKLHTSLPSSCKGLKILSNIKVEVPVKHHKYMVNTVMDLTESDELSYVQRTPSPENSLLDLEEKKEIPKLTDDCAQPCTSSNDSLITNSLSVIKNVGKLHPEDVSIKEDKMEDEFSDSCPVPDLICNEKPSISPCSELLENSENSMDQITSTKPDPSIKIDSKDELTSSLEIKIDSKDELTSSLEIKIDSKDELTSSLELLAGNNKLDHYSPDTSSDFKTKSEIYESGLDAEDLTSGSSSRLSVSPSPDPSIPESSRQNSTLKSESPRSSINLNLQEERKVRNPPKPRNIPLSLNNIFVKKHKKILKIKNKKFASKVVQPKQEPQPSSSNTVPVEIFFDSSVVKKSEDTEDIKEDINKTEDICNKNEVDADTEEQSMDIEPVAPSTISHDDKSNKMDILHIKEEVNTSYEFSCEVDRCNNDDAPFDTIRPINVITYGNIPADKFDDHSDHEELLDSETTKRNKQFVNMMSENYFGDNIYADYFTPDHVEAFDADKESNDSERPDDVWGEPSQKRNEFVLPNLIDNSYKIPYSTKVHYDGNESERKIECSEEPDNKDDILSESRSEGEPPLNICADEHMPPRGELSGQESNGDMESPWSRMYSEVTPTEPYDLIARESWVSDGSDVDVTEKKDNLDDDVQYKCRLHTCTQCGLKFASLKELRAHRTNEHVTATCSAYKTYSRMITARSIKKEEKINDNILAGKHLFDTDVTDPKAALQEYDILRDCKPEIKSLIKQEKKRKRNFICEICKIDQGNDVAFNEHLKLHPLECQTCGKRFYRRANLSLHMKTHLGIKNYKCEVCQKRFITRQKLNEHRNIHTGLAPVKCTVCDETFRRYSNMVQHRNRHHLKKKAKVKDFVCHACGAVFHSAAKLLWHKETHDEKPKACLYCSDRFVHAASLTRHVRRVHNEFYLSDKLRGKVDNVHCHVCKQVYLRTNLRAHLEIHSGKRPYLCVVCNKSFTTKWNLKLHRWTHMSRSAKPYKCTLCKGAFVRHSEYISHMNAHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKFVCKVPECGKSFHRGYYLSEHMKVHSGARPFACNICGKTSSNKSNHNKHVKIHQLRETVATEA*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00875580;
90% Identity: iTF_00874713;
80% Identity: -