Basic Information

Insect: Leptidea juvernica
Gene Symbol: ZFX
Assembly: GCA_949711685.1
Location: CATIXL010000023.1:3884634-3902428[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 3 4.2e+02 3.0 0.3 2 23 6 27 5 27 0.95

2 13 0.00072 0.1 14.4 1.5 1 23 1019 1042 1019 1042 0.94

3 13 1.7e-06 0.00025 22.6 1.4 2 23 1142 1163 1141 1163 0.97

4 13 3.7e-05 0.0052 18.4 1.7 1 23 1169 1191 1169 1191 0.98

5 13 7.9e-05 0.011 17.4 3.0 2 23 1198 1219 1197 1220 0.95

6 13 0.0065 0.92 11.4 0.6 1 23 1230 1252 1230 1252 0.98

7 13 0.012 1.7 10.5 0.7 3 23 1259 1280 1258 1280 0.96

8 13 0.22 32 6.5 2.2 3 23 1298 1317 1296 1317 0.96

9 13 0.0002 0.028 16.1 1.0 1 20 1323 1342 1323 1345 0.89

10 13 0.00086 0.12 14.1 1.3 1 23 1353 1375 1353 1375 0.98

11 13 0.0052 0.73 11.7 7.2 1 23 1381 1403 1381 1403 0.98

12 13 0.00011 0.015 17.0 1.0 1 23 1409 1433 1409 1433 0.97

13 13 0.00037 0.052 15.3 2.3 1 23 1439 1461 1439 1461 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	3	4.2e+02	3.0	0.3	2	23	6	27	5	27	0.95
2	13	0.00072	0.1	14.4	1.5	1	23	1019	1042	1019	1042	0.94
3	13	1.7e-06	0.00025	22.6	1.4	2	23	1142	1163	1141	1163	0.97
4	13	3.7e-05	0.0052	18.4	1.7	1	23	1169	1191	1169	1191	0.98
5	13	7.9e-05	0.011	17.4	3.0	2	23	1198	1219	1197	1220	0.95
6	13	0.0065	0.92	11.4	0.6	1	23	1230	1252	1230	1252	0.98
7	13	0.012	1.7	10.5	0.7	3	23	1259	1280	1258	1280	0.96
8	13	0.22	32	6.5	2.2	3	23	1298	1317	1296	1317	0.96
9	13	0.0002	0.028	16.1	1.0	1	20	1323	1342	1323	1345	0.89
10	13	0.00086	0.12	14.1	1.3	1	23	1353	1375	1353	1375	0.98
11	13	0.0052	0.73	11.7	7.2	1	23	1381	1403	1381	1403	0.98
12	13	0.00011	0.015	17.0	1.0	1	23	1409	1433	1409	1433	0.97
13	13	0.00037	0.052	15.3	2.3	1	23	1439	1461	1439	1461	0.97

Sequence Information

Coding Sequence: atggatCAAAGGGTTCAATGCCCTGTTTGTACATTATACCTTCACAATGGGATGTCATTGGAGTCTCATTTGGATACTCACCCAAAAGATCAGGTGATAAAAGCACTTTGCAGTTTATCTGCCAAAAAATCTAATGATTCAACAGTTACACTAACACCAAGTAGCTCAGAGGGATCTTACAGAAGCAGAACACCTTTAACAGATGATAGTGTAAGATGGTCAACCTCCAGACGGAGCACAGATAGTGGATACTGGCCTAGAACCCCTAGTAGAAATAAATCAGCATCATCAAATGTCTCCAGTAACTGTAATCCTGAACTTCAAAGTGGTGCATCTCATTTtgagaataatttaataaataacagtgcTGAATTCTCAGACTGTGAGGTGAAATCTGTCAAGAGCTCAAATGCATTTACTCCAAATGTTCACCTAACAACTGATTACAACCAACAATATCCATTCTATTCTGAAAATCCCGATGAGAGTGAAGTTAAGTATTCACGAAGTACTGATTATAATGTTACTGATAATGGAAACCAAATTTTTACATATAATGTACCAATTGTAGGTAATATGAAACTACCACCCAGAATTGTACCTGCAAATGCAACAAGAGGaaacaacaatttcattaaatttataccaaaatcAAACAATATGATGGTTAAAAACATTGGAGGTGTAAGATACATGGCACCTAGTGTAAAACCATATTCGATGATGTTTTCTGGAAATAGCATGGGATCAGATATTTTAAGTCCAAAAAACCTAAGTCAGCCAATAGATGGTCAGTTTAATCAAATGGCCCATGAAGGAATAGCACCAAATGCAACTTCTGTTACACAAAATTCACAAATTATCTACAGGGAGATGGTTCACAGTGTTGATGGCAAACCTTATATTTCTAATGTTCCACAGATGCTGAATGGTAATGATAATGCAGCACAAAACAGCTCAATGTATCAAAATATGATGGTTATTGACCAGTTTGGTAATACATCTTGTATGTACAATACACCACCATCTAATTCTATGACTAAAGCTGAGCCAGTCTCCAATGAGTCAAACAAGACCTTGATAATTGAAGTGAGCCCCATGTCAGCAACGGATGAGAAATATATAAAACCAGAAATACTTAATAACCCCACCACTACAGTATCAGATAAATTACATACTTCATTACCCAGCTCTTGTAAAGGTTTGAAAATTCTTAGTAATATTAAAGTTGAGGTTCCTGTTAAGCATCACAAATATATGGTCAACACTGTGATGGATCTCACTGAATCTGATGAGTTGAGCTATGTTCAAAGGACTCCATCACCTGAAAATAGTTTGCTAGATTTAGAAGAGAAGAAAGAAATTCCAAAACTAACTGATGATTGTGCTCAGCCATGTACCTCAAGCAATGACAGTTTAATAACTAATTCATTATCAGTTATAAAAAATGTGGGAAAGTTGCATCCTGAAGATGTTTCTATTAAAGAAGATAAAATGGAAGATGAATTTTCTGACAGTTGTCCAGTACCTGATCTTATTTGTAATGAAAAACCATCTATATCTCCATGTAGTGAATTGTTGGAAAACAGTGAAAACTCTATGGATCAAATAACATCAACTAAGCCTGATCCgtcaatcaaaattgattccaaaGATGAATTGACTAGTTCACttgaaatcaaaattgattccaaaGATGAATTGACTAGTTCACTTGAATTGTTAGCTGGTAACAATAAACTGGATCATTACAGTCCTGACACAAGTTCAGATTTCAAAACAAAAAGTGAAATTTATAAATCAGGGTTGGATGCAGAAGATCTAACATCCGGATCTAGTTCTCGATTAAGTGTTTCACCAAGTCCAGACCCTTCCATACCAGAATCATCTAGACAAGATTCAACATTGAAGTCTGAGTCACCCAGATCctctattaatttaaatcttcaAGAGGAACGCAAGGTACGAAACCCACCAAAGCCTCGTAATATACCATTaagtttgaataatatatttgttaaaaagcacaaaaaaattcttaaaataaaaaataaaaaatttgcttCAAAAGTAGTCCAACCTAAACAAGAACCACAGCCATCTTCTTCAAATACTGTGCcagtagaaatattttttgattcaaGTGTTGTAAAGAAATCTGAAGATACTGAAGACTtaaaagaggatataaataaaacagaagacatttgtaataaaaatgaagTTGATGCTGATACAGAGGAACAATCAATGGATATTGAACCTGTTGCACCCTCCACTATTAGTCATGAtgacaaatcaaataaaatggacattttacatattaaggAAGAGGTTAACACTAGTTATGAATTTAGTTGTGAAGTAGATAGATGCAATAATGATGATGCACCTTTTGATACCATACGTCCAATTAATGTAATTACATATGGGAATATTCCGGCTGACAACTTTGATGATCATTCAGACCATGAAGAACTTTTGGATTCGGAAACtacaaaaagaaataaacagtTTGTTAATATGATGAGTGAAAATTATTTTGGAGACAATATCTATGCTGACTATTTCACACCAGACCATGTAGAAGCTTTTGATGCAGACAAAGAGTCGAAAGATTCAGAAAGACCGGATGATGTATGGGGGGAGCCATCTCAGAAGCGAAATGAATTTGTATTACCAAATTTAATTGACAACAGTTATAAAATTCCGTATAGCACTAAGGTACACTATGATGGGAATGAAAGTGAAAGAAAAATTGAATGTAGGGAGGAACCAGACACCAAGGATGATATTTTGAGTGAAAGCAGAAGTGAAGGAGAGCCACCCTTGAATATATGTGCTGATGAACACATGCCACCTAGAGGAGAACTCAGTGGCCAAGAGAGTAATGGGGACATGGAATCACCATGGAGTCGGATGTATAGTGAAGTGACACCCACGGAGCCTTACGACTTGATTGCTAGAGAGAGTTGGGTGTCTGATGGTTCAGATATTGATGTAACTGAAAAGAAAGATAACTTgGATGATGATGTTCAGTACAAGTGTCGTCTTCATACGTGCACACAGTGTGGCCTCAAGTTTGCCTCGCTAAAGGAACTGCGGGCTCACAGAACGAACGAGCACGTCACGGCAACGTGCTCGGCGTACAAAACCTACAGTCGCATGATCACAGCGAGATCTATCAAGAAAGAAGAGAAGATCAATGATAATATTCTAGCAGGGAAACATCTATTTGATACGGATGTGAAGGACCCCAAGGCGGCCCTACAAGAGTATGATATTCTAAGGGATTGTAAACCGGAAATTAAGAGTTTGATCAAGCAGGAGAAGAAGAGGAAAAGAAACTTCATCTGTGAGATATGCAAGATTGACCAGGGCAACGATGTGGCATTCAATGAACATCTGAAATTGCATCCGTTGGAATGTCAGACTTGTGGGAAAAGGTTCTATAGACGGGCAAACCTTTCGCTGCATATGAAGACACATCTGGGGATAAAGAACTATAAATGTGAAGTATGCCAGAAGCGGTTCATAACCCGACAGAAGTTGAATGAGCATCGCAACATCCACACGGGCCTGGCGCCCGTTAAGTGCACCGTGTGTGACGAGACCTTTAGGAGATATTCCAATATGGTGCAGCATAGAAATCGTCACCACCTCAAGAAGAAAGCGAAGGTGAAGGACTTCGTGTGCCACGCGTGCGGCGCCGTCTTCCACTCGGCGGCCAAGCTGCTGTGGCACAAGGAGACCCATGACGAGAAGCCCAAGGCGTGCCTGTACTGCAGCGACAGGTTCGTGCACGCGGCCTCGCTCACCCGCCACGTGCGCCGCGTGCACAACGAGTTCTACCTGTCCGACAAGCTGCGGGGCAAGGTGGACAACGTGCACTGTCACGTGTGCAAACAGGTGTATCTACGCACAAATCTTCGAGCCCACCTCGAGATTCACAGCGGCAAGCGTCCCTACCTCTGCGTGGTGTGCAACAAATCGTTCACCACCAAATGGAACCTCAAGCTGCACAGGTGGACGCACATGAGCCGGTCCGCCAAGCCCTACAAGTGCACCCTTTGCAAGGGCGCCTTCGTCCGCCACTCCGAGTACATCTCGCACATGAATGCTCACAAGTCGGTGCGGCCATACACGTGCAACTACTGCGGGTGCCAGTTCATAAGGAAGTATAACTGCCAGCGCCACGTCAGGGAACACGAAATGGCGAAGAAGTTTGTGTGCAAAGTGCCTGAGTGTGGTAAGTCCTTCCATAGGGGTTACTACCTGTCCGAGCATATGAAGGTTCACAGTGGGGCACGGCCGTTCGCTTGCAATATATGCGGGAAGACTTCTAGTAACAAATCTAATCACAATAAACACGTTAAGATACATCAATTGAGAGAGACTGTCGCGACTGAAGCGTAA
Protein Sequence: MDQRVQCPVCTLYLHNGMSLESHLDTHPKDQVIKALCSLSAKKSNDSTVTLTPSSSEGSYRSRTPLTDDSVRWSTSRRSTDSGYWPRTPSRNKSASSNVSSNCNPELQSGASHFENNLINNSAEFSDCEVKSVKSSNAFTPNVHLTTDYNQQYPFYSENPDESEVKYSRSTDYNVTDNGNQIFTYNVPIVGNMKLPPRIVPANATRGNNNFIKFIPKSNNMMVKNIGGVRYMAPSVKPYSMMFSGNSMGSDILSPKNLSQPIDGQFNQMAHEGIAPNATSVTQNSQIIYREMVHSVDGKPYISNVPQMLNGNDNAAQNSSMYQNMMVIDQFGNTSCMYNTPPSNSMTKAEPVSNESNKTLIIEVSPMSATDEKYIKPEILNNPTTTVSDKLHTSLPSSCKGLKILSNIKVEVPVKHHKYMVNTVMDLTESDELSYVQRTPSPENSLLDLEEKKEIPKLTDDCAQPCTSSNDSLITNSLSVIKNVGKLHPEDVSIKEDKMEDEFSDSCPVPDLICNEKPSISPCSELLENSENSMDQITSTKPDPSIKIDSKDELTSSLEIKIDSKDELTSSLELLAGNNKLDHYSPDTSSDFKTKSEIYKSGLDAEDLTSGSSSRLSVSPSPDPSIPESSRQDSTLKSESPRSSINLNLQEERKVRNPPKPRNIPLSLNNIFVKKHKKILKIKNKKFASKVVQPKQEPQPSSSNTVPVEIFFDSSVVKKSEDTEDLKEDINKTEDICNKNEVDADTEEQSMDIEPVAPSTISHDDKSNKMDILHIKEEVNTSYEFSCEVDRCNNDDAPFDTIRPINVITYGNIPADNFDDHSDHEELLDSETTKRNKQFVNMMSENYFGDNIYADYFTPDHVEAFDADKESKDSERPDDVWGEPSQKRNEFVLPNLIDNSYKIPYSTKVHYDGNESERKIECREEPDTKDDILSESRSEGEPPLNICADEHMPPRGELSGQESNGDMESPWSRMYSEVTPTEPYDLIARESWVSDGSDIDVTEKKDNLDDDVQYKCRLHTCTQCGLKFASLKELRAHRTNEHVTATCSAYKTYSRMITARSIKKEEKINDNILAGKHLFDTDVKDPKAALQEYDILRDCKPEIKSLIKQEKKRKRNFICEICKIDQGNDVAFNEHLKLHPLECQTCGKRFYRRANLSLHMKTHLGIKNYKCEVCQKRFITRQKLNEHRNIHTGLAPVKCTVCDETFRRYSNMVQHRNRHHLKKKAKVKDFVCHACGAVFHSAAKLLWHKETHDEKPKACLYCSDRFVHAASLTRHVRRVHNEFYLSDKLRGKVDNVHCHVCKQVYLRTNLRAHLEIHSGKRPYLCVVCNKSFTTKWNLKLHRWTHMSRSAKPYKCTLCKGAFVRHSEYISHMNAHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKFVCKVPECGKSFHRGYYLSEHMKVHSGARPFACNICGKTSSNKSNHNKHVKIHQLRETVATEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00875580;
90% Identity: iTF_00875580; iTF_00876455;
80% Identity: -