Lsin033090.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Leptidea sinapis
Gene Symbol
ken
Assembly
GCA_905404315.1
Location
FR990193.1:3905516-3908505[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.4e-16 1.9e-13 51.7 0.0 9 108 29 127 23 129 0.92

Sequence Information

Coding Sequence
ATGGGAGAGGGATTGCTGACTCTCACATACGGCAAGCACCACGCCTGCATCCTAAACGAAGTGGGCGCGGCGTGGCGCGGCGCCCGCTACTCCGATCTGGTGCTGATCTGCGAGGACGCCGTGCCGCTCGCAGCGCATCGGATCGTCATGGCTGCAGCCAGCCCCCTCATCAGaAAAATCCTGGATGACACCCCATCAGTTGAGAATCCGGTGACAATACACATGTCAGGAATCAATAGCACTTTGATGAAGCATCTCTTGGTGTTTCTATATAGCGGCCAGGCATACATTGAGTCGGGAGAGATCGATGATATGCAAGAGTTATTTGAACTCTTAGAAATAAAATCAGATGTTTGGAAGTCTACTAAAGAACGCCAACAAGCTGAAGAAAGGAACCGATCATGTGACAGATTAAAAGCAAAAAGGACTGATATTAACAGCAACGAGAGCAGTAAACATGATGCACCTTCAGGATCATCACATTCCGAAAGTGAAAGGGTTACGCCTAGCGCAGGCTTTAGCAGGGAGAAGGAGAGGGGAGAATCTGAATCCTTAAGTATAAAGAAAGAGAGCATGTCAACCAGCAGTACTGATGAAAGAGATGAAGATGACGCGGAAGGTGATAAGGAGTGCGGCAGATTATCATCGCGCAGACGGAGTTCCTCAAATCCTGTTAATCTGTCTCTTGGCAGAAACGCTGAAACGACTGGTAGTGAACATGATGATTCGCAAGATTTGGATGTTGAAACAGTTGCCGCAAAGAATATTGAACGAAGACGGTCTACAACGTCGAGTCAAGAGGATCCGCCCCCTGAAACTGGTTACCGGAGGCAACTACTGAATGATAGACTGGGAAGGGGCATTGAGAGAACAAAAAGAAAATCACATTACTTGGAACCACCCGAAATGGACTTACGGACCGTTAAATTAGAGGAGTATGCTCATCTAAAACCACCAGATCAAGATCTTATGTCACTCGTGCAAACATCGCCAGAAAATTATGTTGTAACACCCCATCGTAAGCGGAGACCAGGATTTCACAATTCCCCCTCACAAAACCCTCCATTCGTTTCGTTTCCTCCCAGTTATCTTGAAGAAATGGCACATTTACGGTACGCACAAGGCCCTGGCGTGGCTGCAGTAGCTCGACTTGGAGCTCTACATCCACTAAGTGCATCAGCGCCCCCATTCCTTCCAGAGAGAAGTACTACTCCTCCATTAGCAGCACATGATGACACACTTAAATATCGACCTCCAAGTGCGGGTTCTTGGGGTCCTTGGCTCTGTCAACCACAAATGGGCGGGGATGACACCCCAACTGCCGAACATGAACAAGGTTCTAGCAAACAGGCACCAGTCAGAGAATACCGATGCGAGTACTGCGGTAAACAGTTTGGAATGTCTTGGAATCTCAAAACACATCTCCGCGTGCATACAGGTGAAAAGCCATTTGCGTGTCGTCTTTGTGTAGCTATGTTTAAACAAAAGGCACATCTACTGAAACACTTATGCTCGGTCCACCGGAACGTGATATCATCGAGCGAGAATGACGGCCGAACGAATACTCCAGGTCGGTTCAATTGTTGTTTCTGCCAGTTGACTTTCGAAGCGTTGCCGGAACTAATCCGCCACCTTTCCGGGCCGCACAATAGCCTTCTACTCAGTAAAAATTTACATGAATGA
Protein Sequence
MGEGLLTLTYGKHHACILNEVGAAWRGARYSDLVLICEDAVPLAAHRIVMAAASPLIRKILDDTPSVENPVTIHMSGINSTLMKHLLVFLYSGQAYIESGEIDDMQELFELLEIKSDVWKSTKERQQAEERNRSCDRLKAKRTDINSNESSKHDAPSGSSHSESERVTPSAGFSREKERGESESLSIKKESMSTSSTDERDEDDAEGDKECGRLSSRRRSSSNPVNLSLGRNAETTGSEHDDSQDLDVETVAAKNIERRRSTTSSQEDPPPETGYRRQLLNDRLGRGIERTKRKSHYLEPPEMDLRTVKLEEYAHLKPPDQDLMSLVQTSPENYVVTPHRKRRPGFHNSPSQNPPFVSFPPSYLEEMAHLRYAQGPGVAAVARLGALHPLSASAPPFLPERSTTPPLAAHDDTLKYRPPSAGSWGPWLCQPQMGGDDTPTAEHEQGSSKQAPVREYRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNVISSSENDGRTNTPGRFNCCFCQLTFEALPELIRHLSGPHNSLLLSKNLHE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00858738;
90% Identity
iTF_00874945; iTF_00875475; iTF_00875799; iTF_00876666; iTF_00874624; iTF_00358789; iTF_00357796; iTF_01193733; iTF_00359120; iTF_00358168; iTF_01194010; iTF_00354722; iTF_00353697; iTF_00354324; iTF_00353305; iTF_01151362; iTF_01021861; iTF_01080357; iTF_01078694; iTF_01018728; iTF_00458506; iTF_01018221; iTF_01021455; iTF_00843953; iTF_01080050; iTF_01151699; iTF_01019061; iTF_01017879; iTF_00205339; iTF_00205692; iTF_00458204; iTF_01078368; iTF_01182019; iTF_00457651; iTF_00621368; iTF_00621656; iTF_00457371; iTF_01182300; iTF_01562403; iTF_01562147; iTF_00954724; iTF_00953705; iTF_00955245; iTF_00954040; iTF_01386342; iTF_01386889; iTF_01385967; iTF_01387248; iTF_01389047; iTF_01388668; iTF_01080872; iTF_01081186; iTF_00652329; iTF_00720513; iTF_01302951; iTF_00641033; iTF_00651916; iTF_01221133; iTF_00012176; iTF_00072987; iTF_00073372; iTF_00720892; iTF_00012573; iTF_01220798; iTF_01302558; iTF_00146591; iTF_00146944; iTF_00640576; iTF_00827177; iTF_00826443; iTF_00827612; iTF_00825981; iTF_01079500; iTF_01079208; iTF_01506510; iTF_00843689; iTF_01507377; iTF_01507704; iTF_01508222; iTF_01506815; iTF_01508512; iTF_00711151; iTF_00711440; iTF_00710679; iTF_00710366; iTF_00115346; iTF_00115089; iTF_00771220; iTF_00771502; iTF_00145173; iTF_00144801; iTF_00257090; iTF_00896405; iTF_00896097; iTF_00635574; iTF_00635907; iTF_00013244; iTF_00013658; iTF_01564860; iTF_01565243; iTF_00213694; iTF_00214056; iTF_01202891; iTF_01206991; iTF_01204501; iTF_01202615; iTF_01205336; iTF_01203386; iTF_01205053; iTF_01206718; iTF_01203679; iTF_01204223; iTF_00431096; iTF_00430804; iTF_01205851; iTF_01206166; iTF_00879262; iTF_00878985; iTF_01140334; iTF_01140577;
80% Identity
iTF_00874945; iTF_00875475; iTF_00875799; iTF_00876666; iTF_00874624;